United States Biotechnology & Medical Research

Edgewise Therapeutics Inc (EWTX)

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Edgewise Therapeutics Inc. experienced significant selling activity recently, with executives offloading over $7.8 million in net value. These transactions occurred amid a 30.5% stock price increase over the last quarter. Despite the latest earnings report showing a slight miss, shares remain near their 52-week highs, reflecting strong market performance during this period of divestment.
Ticker: EWTX Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
3.8
Donovan Joanne M. CMO Officer
Transaction date
Planned sale
Price
69.83
Quantity 83,914 +28.2%
Value US$3,602,937
3.8
JOANNE DONOVAN Officer Officer
Transaction date
Proposed sale
Price
272.94
Quantity 25,565
Value US$3,185,451
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
443.05
Quantity 45,372 -13.4%
Value US$1,438,078
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
43.68
Quantity 1,000 -6.7%
Value US$100,000
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
43.68
Quantity 1,000 -8.7%
Value US$100,000
2.3
MOORE JOHN R General Counsel Officer
Transaction date
Sale
Price
43.80
Quantity 1,000 -12.0%
Value US$100,000
2.3
MOORE JOHN R General Counsel Officer
Transaction date
Sale
Price
44.50
Quantity 1,000 -0.5%
Value US$100,000
2.3
MOORE JOHN R General Counsel Officer
Transaction date
Sale
Price
44.41
Quantity 1,000 -0.3%
Value US$100,000
2.3
MOORE JOHN R General Counsel Officer
Transaction date
Sale
Price
43.81
Quantity 1,000 -10.7%
Value US$100,000
3.8
Donovan Joanne M. CMO Officer
Transaction date
Sale
Price
44.52
Quantity 1,000 -6.5%
Value US$100,000
3.8
Donovan Joanne M. CMO Officer
Transaction date
Sale
Price
44.43
Quantity 1,000 -0.8%
Value US$100,000
3.8
Donovan Joanne M. CMO Officer
Transaction date
Sale
Price
43.71
Quantity 1,000 -18.3%
Value US$100,000
3.8
Donovan Joanne M. CMO Officer
Transaction date
Sale
Price
43.78
Quantity 1,000 -15.7%
Value US$100,000
2.7
Derakhshan Behrad Chief Business Officer Officer
Transaction date
Sale
Price
43.70
Quantity 1,000 -7.2%
Value US$100,000
2.7
Derakhshan Behrad Chief Business Officer Officer
Transaction date
Sale
Price
44.44
Quantity 1,000 -0.4%
Value US$100,000
2.7
Derakhshan Behrad Chief Business Officer Officer
Transaction date
Sale
Price
44.50
Quantity 1,000 -0.9%
Value US$100,000
2.7
Derakhshan Behrad Chief Business Officer Officer
Transaction date
Sale
Price
43.79
Quantity 1,000 -5.9%
Value US$100,000
2.5
KOCH KEVIN President and CEO Executive Director
Transaction date
Sale
Price
44.33
Quantity 1,000 -1.7%
Value US$100,000
2.5
KOCH KEVIN President and CEO Executive Director
Transaction date
Sale
Price
43.66
Quantity 1,000 -13.4%
Value US$100,000
2.5
KOCH KEVIN President and CEO Executive Director
Transaction date
Sale
Price
43.64
Quantity 1,000 -12.5%
Value US$100,000
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
39.41
Quantity 69,648 -73.9%
Value US$2,744,751
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
39.41
Quantity 130,352 -58.0%
Value US$5,136,651
2.7
ALAN J RUSSELL Director; Officer Executive Director
Transaction date
Proposed sale
Price
40.63
Quantity 200,000
Value US$8,126,000
3.8
JOANNE DONOVAN Officer Officer
Transaction date
Proposed sale
Price
31.45
Quantity 50,000
Value US$1,572,500
3.8
Donovan Joanne M. CMO Officer
Transaction date
Planned sale
Price
38.57
Quantity 50,000 -92.0%
Value US$1,928,400
3.8
Donovan Joanne M. CMO Officer
Transaction date
Planned sale
Price
31.29
Quantity 5,230 -54.5%
Value US$163,663
3.8
Donovan Joanne M. CMO Officer
Transaction date
Planned sale
Price
32.31
Quantity 28,662 -74.9%
Value US$926,095
3.8
Donovan Joanne M. CMO Officer
Transaction date
Planned sale
Price
32.12
Quantity 21,338 -69.0%
Value US$685,308
3.8
Donovan Joanne M. CMO Officer
Transaction date
Sale
Price
30.98
Quantity 6,735 -41.2%
Value US$208,635
3.8
Donovan Joanne M. CMO Officer
Transaction date
Planned sale
Price
30.98
Quantity 9,623 -37.1%
Value US$298,099
3.8
JOANNE DONOVAN Officer Officer
Transaction date
Proposed sale
Price
31.65
Quantity 71,588
Value US$2,265,760
Edris Badreddin Non-Executive Director
Transaction date
Planned sale
Price
29.44
Quantity 66,477 -77.0%
Value US$1,957,083
Edris Badreddin Non-Executive Director
Transaction date
Planned sale
Price
29.44
Quantity 10,463 -10.8%
Value US$308,031
Edris Badreddin Non-Executive Director
Transaction date
Planned sale
Price
29.44
Quantity 7,605 -7.3%
Value US$223,891
Edris Badreddin Non-Executive Director
Transaction date
Planned sale
Price
29.44
Quantity 17,236 -14.2%
Value US$507,428
Edris Badreddin Non-Executive Director
Transaction date
Planned sale
Price
29.44
Quantity 13,690 -10.1%
Value US$403,034
Badreddin Edris Director Non-Executive Director
Transaction date
Proposed sale
Price
29.04
Quantity 115,471
Value US$3,353,279
2.5
ROBERT MICHAEL CARRUTHERS Officer Officer
Transaction date
Proposed sale
Price
28.11
Quantity 183,867
Value US$5,168,722
2.5
ROBERT MICHAEL CARRUTHERS Officer Officer
Transaction date
Proposed sale
Price
26.56
Quantity 180,872
Value US$4,804,322
2.5
ROBERT MICHAEL CARRUTHERS Officer Officer
Transaction date
Proposed sale
Price
22.38
Quantity 70,000
Value US$1,566,586
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
21.12
Quantity 100,000 -81.0%
Value US$2,112,450
2.7
ALAN J RUSSELL Officer; Director Executive Director
Transaction date
Proposed sale
Price
21.12
Quantity 100,000
Value US$2,112,450
3.9
Fox Jonathan C Non-Executive Director
Transaction date
Purchase
Price
18.64
Quantity 10,700 +82.3%
Value US$199,403
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
14.60
Quantity 100,000 -81.0%
Value US$1,459,760
2.7
ALAN J RUSSELL Officer; Director Executive Director
Transaction date
Proposed sale
Price
14.60
Quantity 100,000
Value US$1,459,760
2.5
Carruthers R Michael Chief Financial Officer Officer
Transaction date
Sale
Price
13.39
Quantity 1,428 -1.6%
Value US$19,124
2.5
KOCH KEVIN President and CEO Executive Director
Transaction date
Sale
Price
13.39
Quantity 7,972 -20.7%
Value US$106,764
2.3
MOORE JOHN R General Counsel Officer
Transaction date
Sale
Price
13.39
Quantity 2,098 -17.0%
Value US$28,097
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
13.39
Quantity 1,907 -7.5%
Value US$25,539
3.8
Donovan Joanne M. CMO Officer
Transaction date
Sale
Price
13.39
Quantity 2,862 -10.1%
Value US$38,329
2.7
Derakhshan Behrad Chief Business Officer Officer
Transaction date
Sale
Price
13.39
Quantity 2,491 -9.5%
Value US$33,360
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
16.45
Quantity 1,551 -7.7%
Value US$25,520
2.3
MOORE JOHN R General Counsel Officer
Transaction date
Sale
Price
16.45
Quantity 1,930 -22.8%
Value US$31,757
3.8
Donovan Joanne M. CMO Officer
Transaction date
Sale
Price
16.45
Quantity 5,187 -19.4%
Value US$85,348
2.5
KOCH KEVIN President and CEO Executive Director
Transaction date
Sale
Price
16.45
Quantity 4,276 -17.2%
Value US$70,358
2.7
Derakhshan Behrad Chief Business Officer Officer
Transaction date
Sale
Price
16.45
Quantity 1,691 -7.7%
Value US$27,824
2.5
Carruthers R Michael Chief Financial Officer Officer
Transaction date
Sale
Price
16.45
Quantity 1,314 -1.6%
Value US$21,621
3.0
Thompson Peter A. Non-Executive Director Large shareholder
Transaction date
Purchase
Price
20.13
Quantity 124,193 +38.9%
Value US$2,500,005
3.0
Thompson Peter A. Non-Executive Director Large shareholder
Transaction date
Purchase
Price
20.13
Quantity 372,578 +2.6%
Value US$7,499,995
2.6
ORBIMED ADVISORS LLC Non-Executive Director Large shareholder
Transaction date
Purchase
Price
20.13
Quantity 124,193 +38.9%
Value US$2,500,005
2.6
ORBIMED ADVISORS LLC Non-Executive Director Large shareholder
Transaction date
Purchase
Price
20.13
Quantity 372,578 +2.6%
Value US$7,499,995
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Planned sale
Price
30.02
Quantity 200 -1.3%
Value US$6,004
2.5
KOCH KEVIN President and CEO Executive Director
Transaction date
Planned sale
Price
30.00
Quantity 100 -0.7%
Value US$3,000
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Planned sale
Price
30.13
Quantity 1,200 -7.5%
Value US$36,153
2.5
KOCH KEVIN President and CEO Executive Director
Transaction date
Planned sale
Price
31.13
Quantity 900 -5.9%
Value US$28,018
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Planned sale
Price
30.02
Quantity 8,015 -35.0%
Value US$240,623
2.7
Derakhshan Behrad Chief Business Officer Officer
Transaction date
Planned sale
Price
30.03
Quantity 10,000 -37.3%
Value US$300,300
2.5
KOCH KEVIN President and CEO Executive Director
Transaction date
Planned sale
Price
30.03
Quantity 8,636 -37.4%
Value US$259,298
2.7
Behrad Derakhshan Officer Officer
Transaction date
Proposed sale
Price
29.80
Quantity 40,000
Value US$1,192,000
2.5
KEVIN KOCH Director; Officer Executive Director
Transaction date
Proposed sale
Price
29.50
Quantity 51,181
Value US$1,509,840
2.7
ALAN J RUSSELL Director; Officer Executive Director
Transaction date
Proposed sale
Price
29.50
Quantity 100,000
Value US$2,950,000
3.8
Donovan Joanne M. CMO Officer
Transaction date
Sale
Price
27.63
Quantity 25,000 -60.4%
Value US$690,658
3.8
JOANNE DONOVAN Officer Officer
Transaction date
Proposed sale
Price
27.85
Quantity 25,000
Value US$696,250
2.7
Russell Alan J Chief Scientific Officer Executive Director
Transaction date
Sale
Price
27.37
Quantity 100,000 -87.1%
Value US$2,737,470
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-08-14 2026-08-13 PlS Planned sale
3.8
Donovan Joanne M.

CMO

Officer
83,914 +28.2%
69.83
US$3,602,937 		83,914 +28.2% 69.83 US$3,602,937
2026-08-13 2026-08-13 PrS Proposed sale
3.8
JOANNE DONOVAN

Officer

Officer
25,565
272.94
US$3,185,451 		25,565 272.94 US$3,185,451
2026-08-14 2026-08-12 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
45,372 -13.4%
443.05
US$1,438,078 		45,372 -13.4% 443.05 US$1,438,078
2026-08-14 2026-08-12 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
1,000 -6.7%
43.68
US$100,000 		1,000 -6.7% 43.68 US$100,000
2026-08-14 2026-08-12 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
1,000 -8.7%
43.68
US$100,000 		1,000 -8.7% 43.68 US$100,000
2026-08-14 2026-08-12 S Sale
2.3
MOORE JOHN R

General Counsel

Officer
1,000 -12.0%
43.80
US$100,000 		1,000 -12.0% 43.80 US$100,000
2026-08-14 2026-08-12 S Sale
2.3
MOORE JOHN R

General Counsel

Officer
1,000 -0.5%
44.50
US$100,000 		1,000 -0.5% 44.50 US$100,000
2026-08-14 2026-08-12 S Sale
2.3
MOORE JOHN R

General Counsel

Officer
1,000 -0.3%
44.41
US$100,000 		1,000 -0.3% 44.41 US$100,000
2026-08-14 2026-08-12 S Sale
2.3
MOORE JOHN R

General Counsel

Officer
1,000 -10.7%
43.81
US$100,000 		1,000 -10.7% 43.81 US$100,000
2026-08-14 2026-08-12 S Sale
3.8
Donovan Joanne M.

CMO

Officer
1,000 -6.5%
44.52
US$100,000 		1,000 -6.5% 44.52 US$100,000
2026-08-14 2026-08-12 S Sale
3.8
Donovan Joanne M.

CMO

Officer
1,000 -0.8%
44.43
US$100,000 		1,000 -0.8% 44.43 US$100,000
2026-08-14 2026-08-12 S Sale
3.8
Donovan Joanne M.

CMO

Officer
1,000 -18.3%
43.71
US$100,000 		1,000 -18.3% 43.71 US$100,000
2026-08-14 2026-08-12 S Sale
3.8
Donovan Joanne M.

CMO

Officer
1,000 -15.7%
43.78
US$100,000 		1,000 -15.7% 43.78 US$100,000
2026-08-14 2026-08-12 S Sale
2.7
Derakhshan Behrad

Chief Business Officer

Officer
1,000 -7.2%
43.70
US$100,000 		1,000 -7.2% 43.70 US$100,000
2026-08-14 2026-08-12 S Sale
2.7
Derakhshan Behrad

Chief Business Officer

Officer
1,000 -0.4%
44.44
US$100,000 		1,000 -0.4% 44.44 US$100,000
2026-08-14 2026-08-12 S Sale
2.7
Derakhshan Behrad

Chief Business Officer

Officer
1,000 -0.9%
44.50
US$100,000 		1,000 -0.9% 44.50 US$100,000
2026-08-14 2026-08-12 S Sale
2.7
Derakhshan Behrad

Chief Business Officer

Officer
1,000 -5.9%
43.79
US$100,000 		1,000 -5.9% 43.79 US$100,000
2026-08-14 2026-08-12 S Sale
2.5
KOCH KEVIN

President and CEO

Executive Director
1,000 -1.7%
44.33
US$100,000 		1,000 -1.7% 44.33 US$100,000
2026-08-14 2026-08-12 S Sale
2.5
KOCH KEVIN

President and CEO

Executive Director
1,000 -13.4%
43.66
US$100,000 		1,000 -13.4% 43.66 US$100,000
2026-08-14 2026-08-12 S Sale
2.5
KOCH KEVIN

President and CEO

Executive Director
1,000 -12.5%
43.64
US$100,000 		1,000 -12.5% 43.64 US$100,000
2026-07-02 2026-07-01 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
69,648 -73.9%
39.41
US$2,744,751 		69,648 -73.9% 39.41 US$2,744,751
2026-07-02 2026-07-01 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
130,352 -58.0%
39.41
US$5,136,651 		130,352 -58.0% 39.41 US$5,136,651
2026-07-01 2026-07-01 PrS Proposed sale
2.7
ALAN J RUSSELL

Director; Officer

Executive Director
200,000
40.63
US$8,126,000 		200,000 40.63 US$8,126,000
2026-05-05 2026-05-05 PrS Proposed sale
3.8
JOANNE DONOVAN

Officer

Officer
50,000
31.45
US$1,572,500 		50,000 31.45 US$1,572,500
2026-05-05 2026-05-05 PlS Planned sale
3.8
Donovan Joanne M.

CMO

Officer
50,000 -92.0%
38.57
US$1,928,400 		50,000 -92.0% 38.57 US$1,928,400
2026-05-05 2026-05-04 PlS Planned sale
3.8
Donovan Joanne M.

CMO

Officer
5,230 -54.5%
31.29
US$163,663 		5,230 -54.5% 31.29 US$163,663
2026-04-02 2026-04-01 PlS Planned sale
3.8
Donovan Joanne M.

CMO

Officer
28,662 -74.9%
32.31
US$926,095 		28,662 -74.9% 32.31 US$926,095
2026-03-31 2026-03-31 PlS Planned sale
3.8
Donovan Joanne M.

CMO

Officer
21,338 -69.0%
32.12
US$685,308 		21,338 -69.0% 32.12 US$685,308
2026-03-30 2026-03-27 S Sale
3.8
Donovan Joanne M.

CMO

Officer
6,735 -41.2%
30.98
US$208,635 		6,735 -41.2% 30.98 US$208,635
2026-03-30 2026-03-27 PlS Planned sale
3.8
Donovan Joanne M.

CMO

Officer
9,623 -37.1%
30.98
US$298,099 		9,623 -37.1% 30.98 US$298,099
2026-03-27 2026-03-27 PrS Proposed sale
3.8
JOANNE DONOVAN

Officer

Officer
71,588
31.65
US$2,265,760 		71,588 31.65 US$2,265,760
2026-01-23 2026-01-21 PlS Planned sale
Edris Badreddin
Non-Executive Director
66,477 -77.0%
29.44
US$1,957,083 		66,477 -77.0% 29.44 US$1,957,083
2026-01-23 2026-01-21 PlS Planned sale
Edris Badreddin
Non-Executive Director
10,463 -10.8%
29.44
US$308,031 		10,463 -10.8% 29.44 US$308,031
2026-01-23 2026-01-21 PlS Planned sale
Edris Badreddin
Non-Executive Director
7,605 -7.3%
29.44
US$223,891 		7,605 -7.3% 29.44 US$223,891
2026-01-23 2026-01-21 PlS Planned sale
Edris Badreddin
Non-Executive Director
17,236 -14.2%
29.44
US$507,428 		17,236 -14.2% 29.44 US$507,428
2026-01-23 2026-01-21 PlS Planned sale
Edris Badreddin
Non-Executive Director
13,690 -10.1%
29.44
US$403,034 		13,690 -10.1% 29.44 US$403,034
2026-01-21 2026-01-21 PrS Proposed sale
Badreddin Edris

Director

Non-Executive Director
115,471
29.04
US$3,353,279 		115,471 29.04 US$3,353,279
2026-01-20 2026-01-20 PrS Proposed sale
2.5
ROBERT MICHAEL CARRUTHERS

Officer

Officer
183,867
28.11
US$5,168,722 		183,867 28.11 US$5,168,722
2026-01-15 2026-01-15 PrS Proposed sale
2.5
ROBERT MICHAEL CARRUTHERS

Officer

Officer
180,872
26.56
US$4,804,322 		180,872 26.56 US$4,804,322
2025-12-29 2025-12-26 PrS Proposed sale
2.5
ROBERT MICHAEL CARRUTHERS

Officer

Officer
116,665
26.06
US$3,039,812 		116,665 26.06 US$3,039,812
2025-11-17 2025-11-17 PrS Proposed sale
2.5
ROBERT MICHAEL CARRUTHERS

Officer

Officer
70,000
22.38
US$1,566,586 		70,000 22.38 US$1,566,586
2025-11-13 2025-11-12 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
100,000 -81.0%
21.12
US$2,112,450 		100,000 -81.0% 21.12 US$2,112,450
2025-11-12 2025-11-12 PrS Proposed sale
2.7
ALAN J RUSSELL

Officer; Director

Executive Director
100,000
21.12
US$2,112,450 		100,000 21.12 US$2,112,450
2025-11-13 2025-11-11 B Purchase
3.9
Fox Jonathan C
Non-Executive Director
10,700 +82.3%
18.64
US$199,403 		10,700 +82.3% 18.64 US$199,403
2025-08-28 2025-08-26 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
100,000 -81.0%
14.60
US$1,459,760 		100,000 -81.0% 14.60 US$1,459,760
2025-08-26 2025-08-26 PrS Proposed sale
2.7
ALAN J RUSSELL

Officer; Director

Executive Director
100,000
14.60
US$1,459,760 		100,000 14.60 US$1,459,760
2025-08-14 2025-08-12 S Sale
2.5
Carruthers R Michael

Chief Financial Officer

Officer
1,428 -1.6%
13.39
US$19,124 		1,428 -1.6% 13.39 US$19,124
2025-08-14 2025-08-12 S Sale
2.5
KOCH KEVIN

President and CEO

Executive Director
7,972 -20.7%
13.39
US$106,764 		7,972 -20.7% 13.39 US$106,764
2025-08-14 2025-08-12 S Sale
2.3
MOORE JOHN R

General Counsel

Officer
2,098 -17.0%
13.39
US$28,097 		2,098 -17.0% 13.39 US$28,097
2025-08-14 2025-08-12 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
1,907 -7.5%
13.39
US$25,539 		1,907 -7.5% 13.39 US$25,539
2025-08-14 2025-08-12 S Sale
3.8
Donovan Joanne M.

CMO

Officer
2,862 -10.1%
13.39
US$38,329 		2,862 -10.1% 13.39 US$38,329
2025-08-14 2025-08-12 S Sale
2.7
Derakhshan Behrad

Chief Business Officer

Officer
2,491 -9.5%
13.39
US$33,360 		2,491 -9.5% 13.39 US$33,360
2025-05-07 2025-05-02 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
1,551 -7.7%
16.45
US$25,520 		1,551 -7.7% 16.45 US$25,520
2025-05-07 2025-05-02 S Sale
2.3
MOORE JOHN R

General Counsel

Officer
1,930 -22.8%
16.45
US$31,757 		1,930 -22.8% 16.45 US$31,757
2025-05-07 2025-05-02 S Sale
3.8
Donovan Joanne M.

CMO

Officer
5,187 -19.4%
16.45
US$85,348 		5,187 -19.4% 16.45 US$85,348
2025-05-07 2025-05-02 S Sale
2.5
KOCH KEVIN

President and CEO

Executive Director
4,276 -17.2%
16.45
US$70,358 		4,276 -17.2% 16.45 US$70,358
2025-05-07 2025-05-02 S Sale
2.7
Derakhshan Behrad

Chief Business Officer

Officer
1,691 -7.7%
16.45
US$27,824 		1,691 -7.7% 16.45 US$27,824
2025-05-07 2025-05-02 S Sale
2.5
Carruthers R Michael

Chief Financial Officer

Officer
1,314 -1.6%
16.45
US$21,621 		1,314 -1.6% 16.45 US$21,621
2025-04-04 2025-04-03 B Purchase
3.0
Thompson Peter A.
Non-Executive Director Large shareholder
124,193 +38.9%
20.13
US$2,500,005 		124,193 +38.9% 20.13 US$2,500,005
2025-04-04 2025-04-03 B Purchase
3.0
Thompson Peter A.
Non-Executive Director Large shareholder
372,578 +2.6%
20.13
US$7,499,995 		372,578 +2.6% 20.13 US$7,499,995
2025-04-04 2025-04-03 B Purchase
2.6
ORBIMED ADVISORS LLC
Non-Executive Director Large shareholder
124,193 +38.9%
20.13
US$2,500,005 		124,193 +38.9% 20.13 US$2,500,005
2025-04-04 2025-04-03 B Purchase
2.6
ORBIMED ADVISORS LLC
Non-Executive Director Large shareholder
372,578 +2.6%
20.13
US$7,499,995 		372,578 +2.6% 20.13 US$7,499,995
2025-03-11 2025-03-07 PlS Planned sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
200 -1.3%
30.02
US$6,004 		200 -1.3% 30.02 US$6,004
2025-03-11 2025-03-07 PlS Planned sale
2.5
KOCH KEVIN

President and CEO

Executive Director
100 -0.7%
30.00
US$3,000 		100 -0.7% 30.00 US$3,000
2025-02-07 2025-02-06 PlS Planned sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
1,200 -7.5%
30.13
US$36,153 		1,200 -7.5% 30.13 US$36,153
2025-02-07 2025-02-06 PlS Planned sale
2.5
KOCH KEVIN

President and CEO

Executive Director
900 -5.9%
31.13
US$28,018 		900 -5.9% 31.13 US$28,018
2025-02-07 2025-02-05 PlS Planned sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
8,015 -35.0%
30.02
US$240,623 		8,015 -35.0% 30.02 US$240,623
2025-02-07 2025-02-05 PlS Planned sale
2.7
Derakhshan Behrad

Chief Business Officer

Officer
10,000 -37.3%
30.03
US$300,300 		10,000 -37.3% 30.03 US$300,300
2025-02-07 2025-02-05 PlS Planned sale
2.5
KOCH KEVIN

President and CEO

Executive Director
8,636 -37.4%
30.03
US$259,298 		8,636 -37.4% 30.03 US$259,298
2025-02-05 2025-02-05 PrS Proposed sale
2.7
Behrad Derakhshan

Officer

Officer
40,000
29.80
US$1,192,000 		40,000 29.80 US$1,192,000
2025-02-05 2025-02-05 PrS Proposed sale
2.5
KEVIN KOCH

Director; Officer

Executive Director
51,181
29.50
US$1,509,840 		51,181 29.50 US$1,509,840
2025-02-05 2025-02-05 PrS Proposed sale
2.7
ALAN J RUSSELL

Director; Officer

Executive Director
100,000
29.50
US$2,950,000 		100,000 29.50 US$2,950,000
2025-01-30 2025-01-28 S Sale
3.8
Donovan Joanne M.

CMO

Officer
25,000 -60.4%
27.63
US$690,658 		25,000 -60.4% 27.63 US$690,658
2025-01-28 2025-01-28 PrS Proposed sale
3.8
JOANNE DONOVAN

Officer

Officer
25,000
27.85
US$696,250 		25,000 27.85 US$696,250
2024-12-31 2024-12-30 S Sale
2.7
Russell Alan J

Chief Scientific Officer

Executive Director
100,000 -87.1%
27.37
US$2,737,470 		100,000 -87.1% 27.37 US$2,737,470
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