ORBIMED ADVISORS LLC

Track

Insider profile

Performance

Overall performance
2.6
Performance over holding periods
4.2
30 days 90 days 120 days
Average return 2% 8.2% 15.1%
Success rate 50% 68% 82%
Transactions
318 27% Buy
34 71% Buy
47 69% Buy
Ranking by holding-period performance
Performance for realised trades
4.4
Average return -30%
Success rate 73%
Average holding period 220
Transactions 28
Ranking by realised performance
ORBIMED ADVISORS LLC's trades of Sionna Therapeutics Inc's stock


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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date Company B/S Transaction type Nb. shares
Price
Value 		Number of shares Price Value Details
2026-06-01 2026-05-29
PrS Proposed sale
92,661
155.91
US$3,721,397 		92,661 155.91 US$3,721,397
2026-05-29 2026-05-29
PrS Proposed sale
68,021
346.03
US$3,797,232 		68,021 346.03 US$3,797,232
2026-06-01 2026-05-28
US Q32 Bio Inc (QTTB)
B Purchase
7,673 +40.5%
152.25
US$1,393,884 		7,673 +40.5% 152.25 US$1,393,884
2026-06-01 2026-05-28
US Q32 Bio Inc (QTTB)
B Purchase
1,250,000 +55.5%
8.00
US$10,000,000 		1,250,000 +55.5% 8.00 US$10,000,000
2026-05-29 2026-05-27
PlS Planned sale
101 -0.0%
44.49
US$4,493 		101 -0.0% 44.49 US$4,493
2026-05-11 2026-05-11
PlS Planned sale
184,639 -6.5%
46.22
US$8,534,015 		184,639 -6.5% 46.22 US$8,534,015
2026-05-11 2026-05-08
PlS Planned sale
59,767 -2.0%
44.58
US$2,664,413 		59,767 -2.0% 44.58 US$2,664,413
2026-05-11 2026-05-07
PlS Planned sale
48,546 -1.6%
44.61
US$2,165,637 		48,546 -1.6% 44.61 US$2,165,637
2026-04-23 2026-04-21
B Purchase
1,126,126 +inf%
4.44
US$4,999,999 		1,126,126 +inf% 4.44 US$4,999,999
2026-04-23 2026-04-21
B Purchase
1,689,189 +16.7%
4.44
US$7,499,999 		1,689,189 +16.7% 4.44 US$7,499,999
2026-04-21 2026-04-18
PlS Planned sale
2,948 -0.1%
44.52
US$131,245 		2,948 -0.1% 44.52 US$131,245
2026-04-21 2026-04-17
PlS Planned sale
52,397 -1.7%
44.68
US$2,341,098 		52,397 -1.7% 44.68 US$2,341,098
2026-04-28 2026-04-16
B Purchase
597,729 +98.7%
1.67
US$998,207 		597,729 +98.7% 1.67 US$998,207
2026-04-16 2026-04-16
PlS Planned sale
226,906 -7.0%
45.34
US$10,287,918 		226,906 -7.0% 45.34 US$10,287,918
2026-04-16 2026-04-15
PlS Planned sale
235,863 -6.8%
44.64
US$10,528,924 		235,863 -6.8% 44.64 US$10,528,924
2026-04-16 2026-04-14
PlS Planned sale
47,814 -1.4%
44.51
US$2,128,201 		47,814 -1.4% 44.51 US$2,128,201
2026-04-09 2026-04-09
PrS Proposed sale
78,499
6.55
US$514,168 		78,499 6.55 US$514,168
2026-04-09 2026-04-08
S Sale
40,416 -100.0%
6.52
US$263,512 		40,416 -100.0% 6.52 US$263,512
2026-04-09 2026-04-08
S Sale
32,523 -100.0%
6.29
US$204,570 		32,523 -100.0% 6.29 US$204,570
2026-04-09 2026-04-07
S Sale
2,400 -6.9%
6.38
US$15,312 		2,400 -6.9% 6.38 US$15,312
2026-04-09 2026-04-07
S Sale
29,319 -45.6%
6.53
US$191,453 		29,319 -45.6% 6.53 US$191,453
2026-03-31 2026-03-31
PrS Proposed sale
45,057
11.04
US$497,429 		45,057 11.04 US$497,429
2026-02-04 2026-02-03
S Sale
29,063 -0.8%
44.58
US$1,295,629 		29,063 -0.8% 44.58 US$1,295,629
2026-02-04 2026-02-03
S Sale
29,063 -0.8%
44.58
US$1,295,629 		29,063 -0.8% 44.58 US$1,295,629
2026-02-04 2026-02-02
S Sale
1,890 -0.1%
44.57
US$84,237 		1,890 -0.1% 44.57 US$84,237
2025-12-29 2025-12-24
S Sale
33,356 -0.9%
44.55
US$1,486,010 		33,356 -0.9% 44.55 US$1,486,010
2025-12-19 2025-12-19
S Sale
875 -0.0%
44.49
US$38,929 		875 -0.0% 44.49 US$38,929
2025-12-19 2025-12-18
S Sale
100 -0.0%
44.49
US$4,449 		100 -0.0% 44.49 US$4,449
2025-12-19 2025-12-17
S Sale
900 -0.0%
44.50
US$40,050 		900 -0.0% 44.50 US$40,050
2025-11-26 2025-11-26
S Sale
1,600 -0.0%
44.49
US$71,184 		1,600 -0.0% 44.49 US$71,184
2025-11-26 2025-11-25
S Sale
11,890 -0.3%
44.60
US$530,294 		11,890 -0.3% 44.60 US$530,294
2025-11-26 2025-11-24
S Sale
94,583 -2.6%
44.54
US$4,212,727 		94,583 -2.6% 44.54 US$4,212,727
2025-11-24 2025-11-24
PrS Proposed sale
1,047,770
44.38
US$46,500,033 		1,047,770 44.38 US$46,500,033
2025-10-27 2025-10-23
S Sale
1,000,000 -16.7%
1.52
US$1,520,000 		1,000,000 -16.7% 1.52 US$1,520,000
2025-10-23 2025-10-23
PrS Proposed sale
1,000,000
1.52
US$1,520,000 		1,000,000 1.52 US$1,520,000
2025-10-20 2025-10-20
PrS Proposed sale
482,308
89.94
US$43,378,782 		482,308 89.94 US$43,378,782
2025-10-20 2025-10-20
PrS Proposed sale
186,541
89.94
US$16,777,498 		186,541 89.94 US$16,777,498
2025-10-20 2025-10-20
PrS Proposed sale
746,171
89.94
US$67,110,620 		746,171 89.94 US$67,110,620
2025-10-10 2025-10-08
B Purchase
3,500,000 +353.4%
1.00
US$3,500,000 		3,500,000 +353.4% 1.00 US$3,500,000
2025-10-10 2025-10-08
B Purchase
1,500,000 +19.9%
1.00
US$1,500,000 		1,500,000 +19.9% 1.00 US$1,500,000
2025-09-12 2025-09-10
S Sale
500,000 -7.7%
1.80
US$900,000 		500,000 -7.7% 1.80 US$900,000
2025-09-10 2025-09-10
PrS Proposed sale
2,283,654
1.60
US$3,653,846 		2,283,654 1.60 US$3,653,846
2025-09-02 2025-08-25
B Purchase
1,051,021 +inf%
0.87
US$911,971 		1,051,021 +inf% 0.87 US$911,971
2025-09-02 2025-08-25
B Purchase
5,255,106 +inf%
0.87
US$4,559,855 		5,255,106 +inf% 0.87 US$4,559,855
2025-07-21 2025-07-21
PrS Proposed sale
132,645
5.56
US$737,506 		132,645 5.56 US$737,506