United States Pharmaceuticals

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Avidity Biosciences Inc (RNA)

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Ticker: RNA Exchange: NMS

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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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McCarthy Teresa

Chief Human Resources Officer

2 sales — total 212,206 USD

Planned sale 21 Jan 2026

Value US$4,079,749.45 | Price 155.99 | Shares 11,755

Planned sale 21 Jan 2026

Value US$4,800,404.57 | Price 218.47 | Shares 7,909

Hughes Steven George

Chief Medical Officer

2 sales — total 354,643 USD

Planned sale 21 Jan 2026

Value US$4,685,826.98 | Price 82.20 | Shares 56,108

Planned sale 21 Jan 2026

Value US$717,614.00 | Price 396.77 | Shares 98,955

MacLean Michael F

Chief Financial Officer

2 sales — total 329,068 USD

Planned sale 21 Jan 2026

Value US$198,150.75 | Price 72.45 | Shares 2,735

Planned sale 21 Jan 2026

Value US$130,917.15 | Price 72.45 | Shares 1,807

Flanagan W. Michael

Chief Scientific Officer

2 sales — total 473,388 USD

Planned sale 21 Jan 2026

Value US$185,327.10 | Price 72.45 | Shares 2,558

Planned sale 21 Jan 2026

Value US$288,061.20 | Price 72.45 | Shares 3,976

Boyce Sarah

President and CEO

2 sales — total 1,042,338 USD

Planned sale 21 Jan 2026

Value US$579,092.85 | Price 72.45 | Shares 7,993

Planned sale 21 Jan 2026

Value US$463,245.30 | Price 72.45 | Shares 6,394

LEVIN ARTHUR A

1 sale — total 127,367 USD

Planned sale 21 Jan 2026

Value US$127,367.10 | Price 72.45 | Shares 1,758

Calderaro Charles III

Chief Technical Officer

1 sale — total 269,201 USD

Planned sale 7 Jan 2026

Value US$269,201.21 | Price 72.23 | Shares 3,727

Boyce Sarah

President and CEO

1 sale — total 619,444 USD

Planned sale 7 Jan 2026

Value US$619,444.48 | Price 72.23 | Shares 8,576

Flanagan W. Michael

Chief Scientific Officer

1 sale — total 171,402 USD

Planned sale 7 Jan 2026

Value US$171,401.79 | Price 72.23 | Shares 2,373

Hughes Steven George

Chief Medical Officer

1 sale — total 171,402 USD

Planned sale 7 Jan 2026

Value US$171,401.79 | Price 72.23 | Shares 2,373

Moriarty John B

Chief Legal Officer

1 sale — total 171,474 USD

Planned sale 7 Jan 2026

Value US$171,474.02 | Price 72.23 | Shares 2,374

MacLean Michael F

Chief Financial Officer

1 sale — total 142,582 USD

Planned sale 7 Jan 2026

Value US$142,582.02 | Price 72.23 | Shares 1,974

McCarthy Teresa

Chief Human Resources Officer

1 sale — total 141,932 USD

Planned sale 7 Jan 2026

Value US$141,931.95 | Price 72.23 | Shares 1,965

Hughes Steven George

Chief Medical Officer

1 sale — total 105,015 USD

Planned sale 22 Oct 2025

Value US$105,014.53 | Price 47.54 | Shares 2,209

McCarthy Teresa

Chief Human Resources Officer

1 sale — total 1,003,058 USD

Planned sale 15 Oct 2025

Value US$1,003,058.00 | Price 50.15 | Shares 20,000

Mosbrooker Eric

Chief Commercial Officer

1 sale — total 297,771 USD

Planned sale 3 Oct 2025

Value US$297,771.09 | Price 45.38 | Shares 6,562

Hughes Steven George

Chief Medical Officer

1 sale — total 89,601 USD

Planned sale 22 Sep 2025

Value US$89,600.64 | Price 40.58 | Shares 2,208

McCarthy Teresa

Chief Human Resources Officer

1 sale — total 621,143 USD

Planned sale 15 Sep 2025

Value US$621,142.50 | Price 41.41 | Shares 15,000

Hughes Steven George

Chief Medical Officer

1 sale — total 70,022 USD

Planned sale 15 Sep 2025

Value US$70,022.22 | Price 45.41 | Shares 1,542

Flanagan W. Michael

Chief Scientific Officer

1 sale — total 778,702 USD

Planned sale 11 Sep 2025

Value US$778,702.00 | Price 38.94 | Shares 20,000

WILLIAM MICHAEL FLANAGAN

Officer

1 sale — total 928,000 USD

Proposed sale 11 Sep 2025

Value US$928,000.00 | Price 46.40 | Shares 20,000

WILSON TROY EDWARD

3 sales — total 6,227,600 USD

Planned sale 5 Sep 2025

Value US$750,000.00 | Price 50.00 | Shares 15,000

Planned sale 5 Sep 2025

Value US$725,000.00 | Price 50.00 | Shares 14,500

Proposed sale 5 Sep 2025

Value US$4,752,600.00 | Price 50.00 | Shares 95,052

SARAH BOYCE

Director; Officer

1 sale — total 2,423,500 USD

Proposed sale 5 Sep 2025

Value US$2,423,500.00 | Price 48.47 | Shares 50,000

Boyce Sarah

President and CEO

1 sale — total 2,497,435 USD

Planned sale 5 Sep 2025

Value US$2,497,435.00 | Price 49.95 | Shares 50,000

Mosbrooker Eric

Chief Commercial Officer

1 sale — total 308,936 USD

Planned sale 3 Sep 2025

Value US$308,935.50 | Price 47.07 | Shares 6,563

ERIC MOSBROOKER

Officer

1 sale — total 929,864 USD

Proposed sale 3 Sep 2025

Value US$929,864.24 | Price 47.23 | Shares 19,688

Gallagher Kathleen P.

Chief Program Officer

1 sale — total 8,915 USD

Planned sale 2 Sep 2025

Value US$8,914.96 | Price 47.42 | Shares 188

Boyce Sarah

President and CEO

1 sale — total 1,234,700 USD

Planned sale 28 Aug 2025

Value US$1,234,700.00 | Price 49.39 | Shares 25,000

SARAH BOYCE

Director; Officer

1 sale — total 1,195,500 USD

Proposed sale 28 Aug 2025

Value US$1,195,500.00 | Price 47.82 | Shares 25,000

Hughes Steven George

Chief Medical Officer

1 sale — total 102,462 USD

Planned sale 22 Aug 2025

Value US$102,461.58 | Price 46.40 | Shares 2,208

TERESA MCCARTHY

Officer

1 sale — total 2,073,150 USD

Proposed sale 15 Aug 2025

Value US$2,073,150.00 | Price 46.07 | Shares 45,000

McCarthy Teresa

Chief Human Resources Officer

1 sale — total 465,632 USD

Planned sale 15 Aug 2025

Value US$465,632.00 | Price 46.56 | Shares 10,000

Hughes Steven George

Chief Medical Officer

1 sale — total 71,950 USD

Planned sale 13 Aug 2025

Value US$71,949.72 | Price 46.66 | Shares 1,542

STEVEN GEORGE HUGHES

Officer

1 sale — total 448,847 USD

Proposed sale 13 Aug 2025

Value US$448,847.07 | Price 46.23 | Shares 9,709

MacLean Michael F

Chief Financial Officer

1 sale — total 1,320,844 USD

Planned sale 6 Aug 2025

Value US$1,320,843.93 | Price 42.73 | Shares 30,914

Mosbrooker Eric

Chief Commercial Officer

2 sales — total 5,763,697 USD

Planned sale 6 Aug 2025

Value US$269,663.11 | Price 44.06 | Shares 6,120

Planned sale 6 Aug 2025

Value US$5,494,033.41 | Price 44.06 | Shares 124,687

LEVIN ARTHUR A

1 sale — total 5,118,881 USD

Planned sale 6 Aug 2025

Value US$5,118,881.25 | Price 47.62 | Shares 107,500

WILSON TROY EDWARD

7 sales — total 8,554,860 USD

Planned sale 6 Aug 2025

Value US$799,965.00 | Price 45.00 | Shares 17,777

Planned sale 6 Aug 2025

Value US$799,965.00 | Price 45.00 | Shares 17,777

Planned sale 6 Aug 2025

Value US$675,000.00 | Price 45.00 | Shares 15,000

Planned sale 6 Aug 2025

Value US$675,000.00 | Price 45.00 | Shares 15,000

Planned sale 6 Aug 2025

Value US$337,500.00 | Price 45.00 | Shares 7,500

Planned sale 6 Aug 2025

Value US$990,000.00 | Price 45.00 | Shares 22,000

Proposed sale 6 Aug 2025

Value US$4,277,430.00 | Price 45.00 | Shares 95,054

Hughes Steven George

Chief Medical Officer

5 sales — total 3,480,269 USD

Planned sale 6 Aug 2025

Value US$1,452,341.67 | Price 42.74 | Shares 33,983

Planned sale 6 Aug 2025

Value US$755,039.88 | Price 42.74 | Shares 17,667

Planned sale 6 Aug 2025

Value US$263,560.93 | Price 42.74 | Shares 6,167

Planned sale 6 Aug 2025

Value US$527,121.86 | Price 42.74 | Shares 12,334

Planned sale 6 Aug 2025

Value US$482,204.96 | Price 42.74 | Shares 11,283

ERIC MOSBROOKER

Officer

1 sale — total 5,004,676 USD

Proposed sale 6 Aug 2025

Value US$5,004,675.82 | Price 38.26 | Shares 130,807

STEVEN GEORGE HUGHES

Officer

1 sale — total 3,115,665 USD

Proposed sale 6 Aug 2025

Value US$3,115,664.84 | Price 38.26 | Shares 81,434

ARTHUR LEVIN

Director

1 sale — total 4,112,950 USD

Proposed sale 6 Aug 2025

Value US$4,112,950.00 | Price 38.26 | Shares 107,500

MICHAEL MACLEAN

Officer

1 sale — total 1,182,770 USD

Proposed sale 6 Aug 2025

Value US$1,182,769.64 | Price 38.26 | Shares 30,914

Moriarty John B

Chief Legal Officer

1 sale — total 81,291 USD

Planned sale 4 Aug 2025

Value US$81,291.45 | Price 36.21 | Shares 2,245

Gallagher Kathleen P.

Chief Program Officer

1 sale — total 27,549 USD

Planned sale 17 Jun 2025

Value US$27,548.64 | Price 30.24 | Shares 911

KATHLEEN GALLAGHER

Officer

1 sale — total 27,148 USD

Proposed sale 17 Jun 2025

Value US$27,147.80 | Price 29.80 | Shares 911

Flanagan W. Michael

Chief Scientific Officer

1 sale — total 657,694 USD

Planned sale 11 Jun 2025

Value US$657,694.00 | Price 32.88 | Shares 20,000

WILLIAM MICHAEL FLANAGAN

Officer

1 sale — total 672,400 USD

Proposed sale 11 Jun 2025

Value US$672,400.00 | Price 33.62 | Shares 20,000

Gallagher Kathleen P.

Chief Program Officer

1 sale — total 190,833 USD

Planned sale 2 Jun 2025

Value US$190,832.92 | Price 32.48 | Shares 5,875

KATHLEEN GALLAGHER

Officer

1 sale — total 182,008 USD

Proposed sale 2 Jun 2025

Value US$182,007.50 | Price 30.98 | Shares 5,875

Gallagher Kathleen P.

Chief Program Officer

1 sale — total 190,324 USD

Planned sale 1 May 2025

Value US$190,324.15 | Price 32.40 | Shares 5,875

KATHLEEN GALLAGHER

Officer

1 sale — total 191,819 USD

Proposed sale 1 May 2025

Value US$191,818.75 | Price 32.65 | Shares 5,875

Gallagher Kathleen P.

Chief Program Officer

2 sales — total 163,486 USD

Planned sale 1 Apr 2025

Value US$9,155.21 | Price 27.83 | Shares 329

Planned sale 1 Apr 2025

Value US$154,330.76 | Price 27.83 | Shares 5,546

Boyce Sarah

President and CEO

1 sale — total 979,563 USD

Planned sale 20 Mar 2025

Value US$979,563.01 | Price 31.06 | Shares 31,540

Flanagan W. Michael

Chief Scientific Officer

1 sale — total 365,868 USD

Planned sale 20 Mar 2025

Value US$365,867.95 | Price 31.06 | Shares 11,780

Hughes Steven George

Chief Medical Officer

1 sale — total 297,491 USD

Planned sale 20 Mar 2025

Value US$297,490.76 | Price 31.06 | Shares 9,578

Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Insider and/or position	Nb. shares Price Value	Number of shares	Price	Value
2026-01-23	2026-01-21	PlS Planned sale	McCarthy Teresa Chief Human Resources Officer Officer	11,755 -12.8% 155.99 US$4,079,749	11,755 -12.8%	155.99	US$4,079,749
2026-01-23	2026-01-21	PlS Planned sale	McCarthy Teresa Chief Human Resources Officer Officer	7,909 -46.6% 218.47 US$4,800,405	7,909 -46.6%	218.47	US$4,800,405
2026-01-23	2026-01-21	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	56,108 +28.7% 82.20 US$4,685,827	56,108 +28.7%	82.20	US$4,685,827
2026-01-23	2026-01-21	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	2,017 -5.5% 72.45 US$146,132	2,017 -5.5%	72.45	US$146,132
2026-01-23	2026-01-21	PlS Planned sale	MacLean Michael F Chief Financial Officer Officer	2,735 -4.4% 72.45 US$198,151	2,735 -4.4%	72.45	US$198,151
2026-01-23	2026-01-21	PlS Planned sale	MacLean Michael F Chief Financial Officer Officer	1,807 -2.8% 72.45 US$130,917	1,807 -2.8%	72.45	US$130,917
2026-01-23	2026-01-21	PlS Planned sale	Flanagan W. Michael Chief Scientific Officer Officer	2,558 -2.9% 72.45 US$185,327	2,558 -2.9%	72.45	US$185,327
2026-01-23	2026-01-21	PlS Planned sale	Flanagan W. Michael Chief Scientific Officer Officer	3,976 -4.3% 72.45 US$288,061	3,976 -4.3%	72.45	US$288,061
2026-01-23	2026-01-21	PlS Planned sale	3.5 Boyce Sarah President and CEO Executive Director	7,993 -2.9% 72.45 US$579,093	7,993 -2.9%	72.45	US$579,093
2026-01-23	2026-01-21	PlS Planned sale	3.5 Boyce Sarah President and CEO Executive Director	6,394 -2.3% 72.45 US$463,245	6,394 -2.3%	72.45	US$463,245
2026-01-23	2026-01-21	PlS Planned sale	1.2 LEVIN ARTHUR A Non-Executive Director	1,758 -9.6% 72.45 US$127,367	1,758 -9.6%	72.45	US$127,367
2026-01-09	2026-01-07	PlS Planned sale	Calderaro Charles III Chief Technical Officer Officer	3,727 -7.0% 72.23 US$269,201	3,727 -7.0%	72.23	US$269,201
2026-01-09	2026-01-07	PlS Planned sale	3.5 Boyce Sarah President and CEO Executive Director	8,576 -2.9% 72.23 US$619,444	8,576 -2.9%	72.23	US$619,444
2026-01-09	2026-01-07	PlS Planned sale	Flanagan W. Michael Chief Scientific Officer Officer	2,373 -2.5% 72.23 US$171,402	2,373 -2.5%	72.23	US$171,402
2026-01-09	2026-01-07	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	2,373 -6.1% 72.23 US$171,402	2,373 -6.1%	72.23	US$171,402
2026-01-09	2026-01-07	PlS Planned sale	Moriarty John B Chief Legal Officer Officer	2,374 -3.1% 72.23 US$171,474	2,374 -3.1%	72.23	US$171,474
2026-01-09	2026-01-07	PlS Planned sale	MacLean Michael F Chief Financial Officer Officer	1,974 -3.0% 72.23 US$142,582	1,974 -3.0%	72.23	US$142,582
2026-01-09	2026-01-07	PlS Planned sale	McCarthy Teresa Chief Human Resources Officer Officer	1,965 -1.7% 72.23 US$141,932	1,965 -1.7%	72.23	US$141,932
2025-10-24	2025-10-22	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	2,209 -5.4% 47.54 US$105,015	2,209 -5.4%	47.54	US$105,015
2025-10-17	2025-10-15	PlS Planned sale	McCarthy Teresa Chief Human Resources Officer Officer	20,000 -17.1% 50.15 US$1,003,058	20,000 -17.1%	50.15	US$1,003,058
2025-10-07	2025-10-03	PlS Planned sale	Mosbrooker Eric Chief Commercial Officer Officer	6,562 -10.7% 45.38 US$297,771	6,562 -10.7%	45.38	US$297,771
2025-09-23	2025-09-22	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	2,208 -5.4% 40.58 US$89,601	2,208 -5.4%	40.58	US$89,601
2025-09-17	2025-09-15	PlS Planned sale	McCarthy Teresa Chief Human Resources Officer Officer	15,000 -13.4% 41.41 US$621,142	15,000 -13.4%	41.41	US$621,142
2025-09-17	2025-09-15	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	1,542 -3.8% 45.41 US$70,022	1,542 -3.8%	45.41	US$70,022
2025-09-12	2025-09-11	PlS Planned sale	Flanagan W. Michael Chief Scientific Officer Officer	20,000 -20.0% 38.94 US$778,702	20,000 -20.0%	38.94	US$778,702
2025-09-11	2025-09-11	PrS Proposed sale	WILLIAM MICHAEL FLANAGAN Officer Officer	20,000 46.40 US$928,000	20,000	46.40	US$928,000
2025-09-09	2025-09-05	PlS Planned sale	3.0 WILSON TROY EDWARD Non-Executive Director	15,000 -21.6% 50.00 US$750,000	15,000 -21.6%	50.00	US$750,000
2025-09-09	2025-09-05	PlS Planned sale	3.0 WILSON TROY EDWARD Non-Executive Director	14,500 -17.3% 50.00 US$725,000	14,500 -17.3%	50.00	US$725,000
2025-09-05	2025-09-05	PrS Proposed sale	3.0 WILSON TROY EDWARD Chairman	95,052 50.00 US$4,752,600	95,052	50.00	US$4,752,600
2025-09-05	2025-09-05	PrS Proposed sale	3.5 SARAH BOYCE Director; Officer Executive Director	50,000 48.47 US$2,423,500	50,000	48.47	US$2,423,500
2025-09-05	2025-09-05	PlS Planned sale	3.5 Boyce Sarah President and CEO Executive Director	50,000 -14.1% 49.95 US$2,497,435	50,000 -14.1%	49.95	US$2,497,435
2025-09-05	2025-09-03	PlS Planned sale	Mosbrooker Eric Chief Commercial Officer Officer	6,563 -10.7% 47.07 US$308,936	6,563 -10.7%	47.07	US$308,936
2025-09-03	2025-09-03	PrS Proposed sale	ERIC MOSBROOKER Officer Officer	19,688 47.23 US$929,864	19,688	47.23	US$929,864
2025-09-02	2025-09-02	PlS Planned sale	Gallagher Kathleen P. Chief Program Officer Officer	188 -0.4% 47.42 US$8,915	188 -0.4%	47.42	US$8,915
2025-08-29	2025-08-28	PlS Planned sale	3.5 Boyce Sarah President and CEO Executive Director	25,000 -7.6% 49.39 US$1,234,700	25,000 -7.6%	49.39	US$1,234,700
2025-08-28	2025-08-28	PrS Proposed sale	3.5 SARAH BOYCE Director; Officer Executive Director	25,000 47.82 US$1,195,500	25,000	47.82	US$1,195,500
2025-08-22	2025-08-22	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	2,208 -5.4% 46.40 US$102,462	2,208 -5.4%	46.40	US$102,462
2025-08-15	2025-08-15	PrS Proposed sale	TERESA MCCARTHY Officer Officer	45,000 46.07 US$2,073,150	45,000	46.07	US$2,073,150
2025-08-15	2025-08-15	PlS Planned sale	McCarthy Teresa Chief Human Resources Officer Officer	10,000 -9.3% 46.56 US$465,632	10,000 -9.3%	46.56	US$465,632
2025-08-15	2025-08-13	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	1,542 -3.8% 46.66 US$71,950	1,542 -3.8%	46.66	US$71,950
2025-08-13	2025-08-13	PrS Proposed sale	STEVEN GEORGE HUGHES Officer Officer	9,709 46.23 US$448,847	9,709	46.23	US$448,847
2025-08-15	2025-08-06	PlS Planned sale	MacLean Michael F Chief Financial Officer Officer	30,914 -32.0% 42.73 US$1,320,844	30,914 -32.0%	42.73	US$1,320,844
2025-08-08	2025-08-06	PlS Planned sale	Mosbrooker Eric Chief Commercial Officer Officer	6,120 -10.0% 44.06 US$269,663	6,120 -10.0%	44.06	US$269,663
2025-08-08	2025-08-06	PlS Planned sale	Mosbrooker Eric Chief Commercial Officer Officer	124,687 -67.1% 44.06 US$5,494,033	124,687 -67.1%	44.06	US$5,494,033
2025-08-08	2025-08-06	PlS Planned sale	1.2 LEVIN ARTHUR A Non-Executive Director	107,500 -84.5% 47.62 US$5,118,881	107,500 -84.5%	47.62	US$5,118,881
2025-08-08	2025-08-06	PlS Planned sale	3.0 WILSON TROY EDWARD Non-Executive Director	17,777 -50.0% 45.00 US$799,965	17,777 -50.0%	45.00	US$799,965
2025-08-08	2025-08-06	PlS Planned sale	3.0 WILSON TROY EDWARD Non-Executive Director	17,777 -50.0% 45.00 US$799,965	17,777 -50.0%	45.00	US$799,965
2025-08-08	2025-08-06	PlS Planned sale	3.0 WILSON TROY EDWARD Non-Executive Director	15,000 -5.0% 45.00 US$675,000	15,000 -5.0%	45.00	US$675,000
2025-08-08	2025-08-06	PlS Planned sale	3.0 WILSON TROY EDWARD Non-Executive Director	15,000 -5.0% 45.00 US$675,000	15,000 -5.0%	45.00	US$675,000
2025-08-08	2025-08-06	PlS Planned sale	3.0 WILSON TROY EDWARD Non-Executive Director	7,500 -9.7% 45.00 US$337,500	7,500 -9.7%	45.00	US$337,500
2025-08-08	2025-08-06	PlS Planned sale	3.0 WILSON TROY EDWARD Non-Executive Director	22,000 -24.1% 45.00 US$990,000	22,000 -24.1%	45.00	US$990,000
2025-08-08	2025-08-06	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	33,983 -46.6% 42.74 US$1,452,342	33,983 -46.6%	42.74	US$1,452,342
2025-08-08	2025-08-06	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	17,667 -19.5% 42.74 US$755,040	17,667 -19.5%	42.74	US$755,040
2025-08-08	2025-08-06	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	6,167 -7.8% 42.74 US$263,561	6,167 -7.8%	42.74	US$263,561
2025-08-08	2025-08-06	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	12,334 -14.5% 42.74 US$527,122	12,334 -14.5%	42.74	US$527,122
2025-08-08	2025-08-06	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	11,283 -13.4% 42.74 US$482,205	11,283 -13.4%	42.74	US$482,205
2025-08-06	2025-08-06	PrS Proposed sale	3.0 WILSON TROY EDWARD Chairman	95,054 45.00 US$4,277,430	95,054	45.00	US$4,277,430
2025-08-06	2025-08-06	PrS Proposed sale	ERIC MOSBROOKER Officer Officer	130,807 38.26 US$5,004,676	130,807	38.26	US$5,004,676
2025-08-06	2025-08-06	PrS Proposed sale	STEVEN GEORGE HUGHES Officer Officer	81,434 38.26 US$3,115,665	81,434	38.26	US$3,115,665
2025-08-06	2025-08-06	PrS Proposed sale	1.2 ARTHUR LEVIN Director Non-Executive Director	107,500 38.26 US$4,112,950	107,500	38.26	US$4,112,950
2025-08-06	2025-08-06	PrS Proposed sale	MICHAEL MACLEAN Officer Officer	30,914 38.26 US$1,182,770	30,914	38.26	US$1,182,770
2025-08-05	2025-08-04	PlS Planned sale	Moriarty John B Chief Legal Officer Officer	2,245 -4.5% 36.21 US$81,291	2,245 -4.5%	36.21	US$81,291
2025-06-18	2025-06-17	PlS Planned sale	Gallagher Kathleen P. Chief Program Officer Officer	911 -1.8% 30.24 US$27,549	911 -1.8%	30.24	US$27,549
2025-06-17	2025-06-17	PrS Proposed sale	KATHLEEN GALLAGHER Officer Officer	911 29.80 US$27,148	911	29.80	US$27,148
2025-06-12	2025-06-11	PlS Planned sale	Flanagan W. Michael Chief Scientific Officer Officer	20,000 -20.0% 32.88 US$657,694	20,000 -20.0%	32.88	US$657,694
2025-06-11	2025-06-11	PrS Proposed sale	WILLIAM MICHAEL FLANAGAN Officer Officer	20,000 33.62 US$672,400	20,000	33.62	US$672,400
2025-06-04	2025-06-02	PlS Planned sale	Gallagher Kathleen P. Chief Program Officer Officer	5,875 -10.4% 32.48 US$190,833	5,875 -10.4%	32.48	US$190,833
2025-06-02	2025-06-02	PrS Proposed sale	KATHLEEN GALLAGHER Officer Officer	5,875 30.98 US$182,008	5,875	30.98	US$182,008
2025-05-02	2025-05-01	PlS Planned sale	Gallagher Kathleen P. Chief Program Officer Officer	5,875 -10.4% 32.40 US$190,324	5,875 -10.4%	32.40	US$190,324
2025-05-01	2025-05-01	PrS Proposed sale	KATHLEEN GALLAGHER Officer Officer	5,875 32.65 US$191,819	5,875	32.65	US$191,819
2025-04-03	2025-04-01	PlS Planned sale	Gallagher Kathleen P. Chief Program Officer Officer	329 -0.6% 27.83 US$9,155	329 -0.6%	27.83	US$9,155
2025-04-03	2025-04-01	PlS Planned sale	Gallagher Kathleen P. Chief Program Officer Officer	5,546 -9.9% 27.83 US$154,331	5,546 -9.9%	27.83	US$154,331
2025-03-21	2025-03-20	PlS Planned sale	3.5 Boyce Sarah President and CEO Executive Director	31,540 -9.3% 31.06 US$979,563	31,540 -9.3%	31.06	US$979,563
2025-03-21	2025-03-20	PlS Planned sale	Flanagan W. Michael Chief Scientific Officer Officer	11,780 -12.8% 31.06 US$365,868	11,780 -12.8%	31.06	US$365,868
2025-03-21	2025-03-20	PlS Planned sale	Hughes Steven George Chief Medical Officer Officer	9,578 -11.6% 31.06 US$297,491	9,578 -11.6%	31.06	US$297,491