United States Biotechnology & Medical Research

Regulus Therapeutics Inc (RGLS)

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Ticker: RGLS Exchange: NAS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Regulus Therapeutics Inc. Upgrade to see score, net flow, insiders and the full signal context.

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Top insiders
Trades
Buy 3 Jun 2025
Value US$4,210,030.47 | Price 117.54 | Shares 19,421 (+36.5%)
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2025-06-04 2025-06-03 B Purchase
Klassen Preston

President & Head of R & D

Executive Director
19,421 +36.5%
117.54
US$4,210,030 		19,421 +36.5% 117.54 US$4,210,030
2025-01-31 2025-01-30 B Purchase
3.9
Hagan Joseph P

Chief Executive Officer

Executive Director
40,582 -47.2%
80.58
US$1,923,818 		40,582 -47.2% 80.58 US$1,923,818
2025-01-31 2025-01-30 B Purchase
3.4
BALTIMORE DAVID
Non-Executive Director
29,681 -36.5%
307.29
US$1,140,054 		29,681 -36.5% 307.29 US$1,140,054
2025-01-15 2025-01-14 PlS Planned sale
0.5
CALSADA CRISPINA

Chief Financial Officer

Officer
5,088 -10.1%
1.26
US$6,427 		5,088 -10.1% 1.26 US$6,427
2025-01-15 2025-01-14 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel

Officer
5,088 -9.3%
1.26
US$6,427 		5,088 -9.3% 1.26 US$6,427
2025-01-15 2025-01-14 PlS Planned sale
3.9
Hagan Joseph P

Chief Executive Officer

Executive Director
11,764 -5.3%
1.26
US$14,860 		11,764 -5.3% 1.26 US$14,860
2025-01-15 2025-01-13 PlS Planned sale
0.5
CALSADA CRISPINA

Chief Financial Officer

Officer
38,716 -43.4%
1.26
US$48,906 		38,716 -43.4% 1.26 US$48,906
2025-01-15 2025-01-13 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel

Officer
38,547 -41.4%
1.26
US$48,693 		38,547 -41.4% 1.26 US$48,693
2025-01-15 2025-01-13 PlS Planned sale
Klassen Preston

President & Head of R & D

Executive Director
31,445 -46.6%
1.26
US$39,721 		31,445 -46.6% 1.26 US$39,721
2025-01-15 2025-01-13 PlS Planned sale
3.9
Hagan Joseph P

Chief Executive Officer

Executive Director
115,290 -34.1%
1.26
US$145,634 		115,290 -34.1% 1.26 US$145,634
2024-07-29 2024-07-25 B Purchase
1.3
Collier Kathryn J
Non-Executive Director
4,000 +146.0%
1.82
US$7,280 		4,000 +146.0% 1.82 US$7,280
2024-01-18 2024-01-18 S Sale
0.5
CALSADA CRISPINA

Chief Financial Officer

Officer
5,468 -48.6%
1.19
US$6,510 		5,468 -48.6% 1.19 US$6,510
2024-01-18 2024-01-18 PlS Planned sale
3.9
Hagan Joseph P

Chief Executive Officer

Executive Director
14,580 -20.3%
1.19
US$17,359 		14,580 -20.3% 1.19 US$17,359
2024-01-18 2024-01-18 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel

Officer
5,468 -35.2%
1.19
US$6,510 		5,468 -35.2% 1.19 US$6,510
2022-03-01 2022-03-01 B Purchase
2.9
Drygin Denis

Chief Scientific Officer

Officer
76,686 +328.9%
0.23
US$17,638 		76,686 +328.9% 0.23 US$17,638
2022-02-07 2022-02-04 B Purchase
2.9
Drygin Denis

Chief Scientific Officer

Officer
23,314 +inf%
0.23
US$5,362 		23,314 +inf% 0.23 US$5,362
2022-01-26 2022-01-26 B Purchase
3.9
Hagan Joseph P

President and CEO

Executive Director
100,000 +31.5%
0.22
US$21,520 		100,000 +31.5% 0.22 US$21,520
2021-05-17 2021-05-17 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel

Officer
860 -2.0%
0.89
US$765 		860 -2.0% 0.89 US$765
2021-05-17 2021-05-17 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
4,186 -1.3%
0.89
US$3,726 		4,186 -1.3% 0.89 US$3,726
2021-02-17 2021-02-16 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel

Officer
828 -1.9%
1.72
US$1,424 		828 -1.9% 1.72 US$1,424
2021-02-17 2021-02-16 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
4,144 -0.8%
1.72
US$7,128 		4,144 -0.8% 1.72 US$7,128
2020-12-07 2020-12-04 B Purchase
2.1
MAKOWER JOSHUA
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-12-07 2020-12-04 B Purchase
2.1
Sonsini Peter W.
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-12-07 2020-12-04 B Purchase
1.5
Behbahani Ali
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-12-07 2020-12-04 B Purchase
3.9
Walker Paul Edward
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-12-07 2020-12-04 B Purchase
2.7
Florence Anthony A. Jr.
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-12-07 2020-12-04 B Purchase
2.5
BASKETT FOREST
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-12-07 2020-12-04 B Purchase
Growth Equity Opportunities V, LLC
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-12-07 2020-12-04 B Purchase
3.6
Chang Carmen
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-12-07 2020-12-04 B Purchase
2.4
SANDELL SCOTT D
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-12-07 2020-12-04 B Purchase
2.9
Makhzoumi Mohamad
Large shareholder
4,398,602 +214.3%
0.62
US$2,735,930 		4,398,602 +214.3% 0.62 US$2,735,930
2020-11-18 2020-11-16 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
6,094 -2.7%
0.52
US$3,176 		6,094 -2.7% 0.52 US$3,176
2020-11-18 2020-11-16 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel

Officer
876 -3.3%
0.52
US$456 		876 -3.3% 0.52 US$456
2020-08-17 2020-08-14 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel

Officer
872 -3.2%
0.61
US$528 		872 -3.2% 0.61 US$528
2020-08-17 2020-08-14 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
4,245 -1.9%
0.60
US$2,568 		4,245 -1.9% 0.60 US$2,568
2020-05-18 2020-05-15 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
4,426 -1.9%
0.63
US$2,774 		4,426 -1.9% 0.63 US$2,774
2020-05-18 2020-05-15 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel

Officer
909 -3.2%
0.63
US$570 		909 -3.2% 0.63 US$570
2020-02-19 2020-02-18 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel

Officer
888 -3.0%
0.83
US$737 		888 -3.0% 0.83 US$737
2020-02-19 2020-02-18 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
4,324 -1.8%
0.83
US$3,591 		4,324 -1.8% 0.83 US$3,591
2020-01-03 2020-01-02 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel
2,239 -7.1%
0.97
US$2,164 		2,239 -7.1% 0.97 US$2,164
2020-01-03 2020-01-02 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
8,345 -3.4%
0.97
US$8,067 		8,345 -3.4% 0.97 US$8,067
2019-11-15 2019-11-14 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
5,838 -2.3%
0.64
US$3,736 		5,838 -2.3% 0.64 US$3,736
2019-11-15 2019-11-14 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel
833 -2.6%
0.64
US$533 		833 -2.6% 0.64 US$533
2019-10-02 2019-10-01 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel
2,346 -6.8%
0.68
US$1,602 		2,346 -6.8% 0.68 US$1,602
2019-10-02 2019-10-01 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
8,743 -3.4%
0.68
US$5,969 		8,743 -3.4% 0.68 US$5,969
2019-08-16 2019-08-15 PlS Planned sale Aker Christopher Ray

Sr. VP & General Counsel

Officer
899 -2.5%
0.55
US$495 		899 -2.5% 0.55 US$495
2019-08-16 2019-08-15 PlS Planned sale Hagan Joseph P

President and CEO

Executive Director
4,375 -1.7%
0.55
US$2,409 		4,375 -1.7% 0.55 US$2,409
2019-07-02 2019-07-01 PlS Planned sale
3.0
Chevallard Daniel R.

Chief Financial Officer
2,669 -3.3%
1.31
US$3,500 		2,669 -3.3% 1.31 US$3,500
2019-07-02 2019-07-01 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
5,783 -2.2%
1.31
US$7,584 		5,783 -2.2% 1.31 US$7,584
2019-07-02 2019-07-01 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel
2,225 -5.9%
1.31
US$2,918 		2,225 -5.9% 1.31 US$2,918
2019-05-16 2019-05-16 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
39,352 -12.8%
1.22
US$47,966 		39,352 -12.8% 1.22 US$47,966
2019-05-16 2019-05-15 PlS Planned sale
3.0
Chevallard Daniel R.

Chief Financial Officer
10,000 -11.0%
1.41
US$14,089 		10,000 -11.0% 1.41 US$14,089
2019-05-16 2019-05-15 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel
6,950 -10.5%
1.41
US$9,796 		6,950 -10.5% 1.41 US$9,796
2019-05-09 2019-05-07 B Purchase
2.7
Florence Anthony A. Jr.
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
Growth Equity Opportunities V, LLC
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
2.1
Sonsini Peter W.
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
3.6
Chang Carmen
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
2.9
Makhzoumi Mohamad
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
3.9
Walker Paul Edward
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
1.5
Behbahani Ali
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
2.5
BASKETT FOREST
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
2.4
SANDELL SCOTT D
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
2.1
MAKOWER JOSHUA
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
4.0
MOTT DAVID M
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-09 2019-05-07 B Purchase
0.5
BARRIS PETER J
Large shareholder
1,136,704 +124.1%
1.08
US$1,227,640 		1,136,704 +124.1% 1.08 US$1,227,640
2019-05-08 2019-05-07 B Purchase
Witz Pascale
29,630 +360.5%
1.08
US$32,000 		29,630 +360.5% 1.08 US$32,000
2019-05-08 2019-05-07 B Purchase
3.9
Hagan Joseph P

President and CEO

Executive Director
33,194 +105.9%
1.08
US$35,850 		33,194 +105.9% 1.08 US$35,850
2019-05-08 2019-05-07 B Purchase
3.7
PAPADOPOULOS STELIOS
Non-Executive Director
370,370 +45.2%
1.08
US$400,000 		370,370 +45.2% 1.08 US$400,000
2019-05-08 2019-05-07 B Purchase
3.0
RASTETTER WILLIAM H
Non-Executive Director
92,889 +151.4%
1.08
US$100,320 		92,889 +151.4% 1.08 US$100,320
2019-04-03 2019-04-01 PlS Planned sale
3.9
Hagan Joseph P

President and CEO

Executive Director
5,842 -15.7%
0.98
US$5,731 		5,842 -15.7% 0.98 US$5,731
2019-04-03 2019-04-01 PlS Planned sale
3.0
Chevallard Daniel R.

Chief Financial Officer
3,253 -25.8%
0.98
US$3,192 		3,253 -25.8% 0.98 US$3,192
2019-04-03 2019-04-01 PlS Planned sale
Aker Christopher Ray

Sr. VP & General Counsel
2,710 -30.1%
0.98
US$2,659 		2,710 -30.1% 0.98 US$2,659
2019-01-02 2018-12-28 B Purchase
3.7
PAPADOPOULOS STELIOS
Non-Executive Director
50,000 +6.4%
1.09
US$54,570 		50,000 +6.4% 1.09 US$54,570
2018-12-28 2018-12-27 B Purchase PAPADOPOULOS STELIOS Non-Executive Director
26,401 +3.5%
1.04
US$27,460 		26,401 +3.5% 1.04 US$27,460
2018-12-28 2018-12-26 B Purchase
3.7
PAPADOPOULOS STELIOS
Non-Executive Director
90,000 +13.5%
0.95
US$85,878 		90,000 +13.5% 0.95 US$85,878
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