|
2023-12-06 |
2023-12-06 |
B
Purchase
|
Non-Executive Director
|
25,679
+46.6%
286.05
US$815,730
|
25,679
+46.6%
|
286.05
|
US$815,730
|
|
|
2023-12-06 |
2023-12-05 |
B
Purchase
|
Non-Executive Director
|
68,440
-23.2%
204.04
US$2,908,354
|
68,440
-23.2%
|
204.04
|
US$2,908,354
|
|
|
2023-12-06 |
2023-12-04 |
B
Purchase
|
Non-Executive Director
|
52,605
+4.5%
483.70
US$1,245,481
|
52,605
+4.5%
|
483.70
|
US$1,245,481
|
|
|
2023-11-30 |
2023-11-29 |
B
Purchase
|
Chief Executive Officer
Executive Director
|
4,100
+0.6%
3.51
US$14,403
|
4,100
+0.6%
|
3.51
|
US$14,403
|
|
|
2023-11-30 |
2023-11-28 |
B
Purchase
|
President
Officer
|
3,000
+5.2%
3.27
US$9,812
|
3,000
+5.2%
|
3.27
|
US$9,812
|
|
|
2023-11-30 |
2023-11-28 |
B
Purchase
|
Chief Executive Officer
Executive Director
|
900
+0.1%
3.33
US$2,995
|
900
+0.1%
|
3.33
|
US$2,995
|
|
|
2023-09-21 |
2023-09-21 |
B
Purchase
|
President
Officer
|
2,900
+5.3%
2.40
US$6,970
|
2,900
+5.3%
|
2.40
|
US$6,970
|
|
|
2023-09-21 |
2023-09-20 |
B
Purchase
|
President
Officer
|
600
+1.1%
2.54
US$1,525
|
600
+1.1%
|
2.54
|
US$1,525
|
|
|
2023-09-21 |
2023-09-20 |
B
Purchase
|
General Counsel & Secretary
Officer
|
1,500
+8.9%
2.58
US$3,870
|
1,500
+8.9%
|
2.58
|
US$3,870
|
|
|
2023-09-21 |
2023-09-20 |
B
Purchase
|
Chief Executive Officer
Executive Director
|
10,000
+1.5%
2.50
US$25,042
|
10,000
+1.5%
|
2.50
|
US$25,042
|
|
|
2023-09-21 |
2023-09-19 |
B
Purchase
|
Non-Executive Director
|
2,000
+15.4%
2.37
US$4,745
|
2,000
+15.4%
|
2.37
|
US$4,745
|
|
|
2023-09-19 |
2023-09-18 |
B
Purchase
|
Non-Executive Director
|
2,500
+23.9%
2.08
US$5,200
|
2,500
+23.9%
|
2.08
|
US$5,200
|
|
|
2023-09-19 |
2023-09-18 |
B
Purchase
|
Chief Financial Officer
Officer
|
5,000
+42.1%
2.13
US$10,672
|
5,000
+42.1%
|
2.13
|
US$10,672
|
|
|
2023-09-19 |
2023-09-15 |
B
Purchase
|
Non-Executive Director
|
500
+5.0%
2.18
US$1,090
|
500
+5.0%
|
2.18
|
US$1,090
|
|
|
2023-09-15 |
2023-09-14 |
B
Purchase
|
Chief Scientific Officer
Officer
|
10,000
+85.5%
2.00
US$20,000
|
10,000
+85.5%
|
2.00
|
US$20,000
|
|
|
2023-06-16 |
2023-06-16 |
B
Purchase
|
Chief Financial Officer
Officer
|
5,000
+72.7%
2.92
US$14,600
|
5,000
+72.7%
|
2.92
|
US$14,600
|
|
|
2023-03-21 |
2023-03-20 |
S
Sale
|
General Counsel & Secretary
Officer
|
544
-3.0%
3.29
US$1,788
|
544
-3.0%
|
3.29
|
US$1,788
|
|
|
2023-03-21 |
2023-03-20 |
S
Sale
|
Chief Executive Officer
Executive Director
|
1,119
-0.2%
3.29
US$3,678
|
1,119
-0.2%
|
3.29
|
US$3,678
|
|
|
2023-03-21 |
2023-03-20 |
S
Sale
|
President
Officer
|
872
-1.3%
3.29
US$2,866
|
872
-1.3%
|
3.29
|
US$2,866
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
General Counsel & Secretary
Officer
|
22
-0.1%
5.23
US$115
|
22
-0.1%
|
5.23
|
US$115
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
General Counsel & Secretary
Officer
|
745
-3.9%
4.94
US$3,677
|
745
-3.9%
|
4.94
|
US$3,677
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
Chief Executive Officer
Executive Director
|
44
-0.0%
5.23
US$230
|
44
-0.0%
|
5.23
|
US$230
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
Chief Executive Officer
Executive Director
|
1,536
-0.2%
4.93
US$7,578
|
1,536
-0.2%
|
4.93
|
US$7,578
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
President
Officer
|
1
-0.0%
5.25
US$5
|
1
-0.0%
|
5.25
|
US$5
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
President
Officer
|
34
-0.1%
5.23
US$178
|
34
-0.1%
|
5.23
|
US$178
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
President
Officer
|
1,196
-1.7%
4.94
US$5,902
|
1,196
-1.7%
|
4.94
|
US$5,902
|
|
|
2023-01-04 |
2022-12-30 |
B
Purchase
|
Non-Executive Director
|
1,000
+inf%
6.23
US$6,225
|
1,000
+inf%
|
6.23
|
US$6,225
|
|
|
2023-01-04 |
2022-12-30 |
B
Purchase
|
Non-Executive Director
|
1,001
+inf%
6.23
US$6,231
|
1,001
+inf%
|
6.23
|
US$6,231
|
|
|
2023-01-04 |
2022-12-30 |
B
Purchase
|
Non-Executive Director
|
5,000
+100.9%
6.23
US$31,125
|
5,000
+100.9%
|
6.23
|
US$31,125
|
|
|
2022-12-06 |
2022-12-02 |
S
Sale
|
President and CEO
Executive Director
|
10,890
-10.8%
1.69
US$18,418
|
10,890
-10.8%
|
1.69
|
US$18,418
|
|
|
2022-12-06 |
2022-12-02 |
S
Sale
|
Principal Accounting Officer
Officer
|
1,976
-18.2%
1.69
US$3,341
|
1,976
-18.2%
|
1.69
|
US$3,341
|
|
|
2022-12-06 |
2022-12-02 |
S
Sale
|
See Remarks
Officer
|
3,116
-18.2%
1.69
US$5,270
|
3,116
-18.2%
|
1.69
|
US$5,270
|
|
|
2022-12-06 |
2022-12-02 |
S
Sale
|
SVP and General Counsel
Officer
|
3,116
-18.2%
1.69
US$5,269
|
3,116
-18.2%
|
1.69
|
US$5,269
|
|
|
2022-07-06 |
2022-07-05 |
S
Sale
|
President and CEO
Executive Director
|
4,584
-4.3%
1.85
US$8,476
|
4,584
-4.3%
|
1.85
|
US$8,476
|
|
|
2022-06-06 |
2022-06-03 |
S
Sale
|
SVP and General Counsel
Officer
|
2,923
-14.6%
1.19
US$3,492
|
2,923
-14.6%
|
1.19
|
US$3,492
|
|
|
2022-06-06 |
2022-06-03 |
S
Sale
|
President and CEO
Executive Director
|
10,206
-8.8%
1.19
US$12,192
|
10,206
-8.8%
|
1.19
|
US$12,192
|
|
|
2022-06-06 |
2022-06-03 |
S
Sale
|
Principal Accounting Officer
Officer
|
1,806
-14.3%
1.19
US$2,157
|
1,806
-14.3%
|
1.19
|
US$2,157
|
|
|
2022-06-06 |
2022-06-03 |
S
Sale
|
See Remarks
Officer
|
2,887
-14.4%
1.19
US$3,449
|
2,887
-14.4%
|
1.19
|
US$3,449
|
|
|
2022-03-30 |
2022-03-28 |
PlS
Planned sale
|
President and CEO
Executive Director
|
10,715
-8.5%
1.85
US$19,775
|
10,715
-8.5%
|
1.85
|
US$19,775
|
|
|
2022-02-07 |
2022-02-03 |
S
Sale
|
Chief Business Officer
Officer
|
1,958
-3.2%
1.83
US$3,583
|
1,958
-3.2%
|
1.83
|
US$3,583
|
|
|
2019-11-29 |
2019-11-27 |
S
Sale
|
New Enterprise Associates 12, Limited Partnership
Large shareholder
|
1,166,755
-21.5%
2.52
US$2,941,739
|
1,166,755
-21.5%
|
2.52
|
US$2,941,739
|
|
|
2019-11-29 |
2019-11-26 |
S
Sale
|
New Enterprise Associates 12, Limited Partnership
Large shareholder
|
117,164
-2.1%
2.45
US$287,134
|
117,164
-2.1%
|
2.45
|
US$287,134
|
|
|
2019-02-05 |
2019-02-04 |
PlS
Planned sale
|
See Remarks
Officer
|
9,931
-35.0%
2.99
US$29,700
|
9,931
-35.0%
|
2.99
|
US$29,700
|
|
|
2019-02-05 |
2019-02-04 |
PlS
Planned sale
|
Chief Development Officer
Officer
|
9,189
-38.1%
2.99
US$27,480
|
9,189
-38.1%
|
2.99
|
US$27,480
|
|
|
2019-02-05 |
2019-02-04 |
PlS
Planned sale
|
President and CEO
Executive Director
|
16,478
-17.0%
2.99
US$49,305
|
16,478
-17.0%
|
2.99
|
US$49,305
|
|
|
2019-02-05 |
2019-02-04 |
PlS
Planned sale
|
Chief Scientific Officer
Officer
|
9,514
-38.1%
2.99
US$28,454
|
9,514
-38.1%
|
2.99
|
US$28,454
|
|
|
2019-01-30 |
2019-01-29 |
PlS
Planned sale
|
See Remarks
Officer
|
712
-23.5%
3.00
US$2,136
|
712
-23.5%
|
3.00
|
US$2,136
|
|
|
2019-01-30 |
2019-01-28 |
PlS
Planned sale
|
See Remarks
Officer
|
1,600
-34.6%
3.00
US$4,800
|
1,600
-34.6%
|
3.00
|
US$4,800
|
|
|
2018-10-26 |
2018-10-26 |
B
Purchase
|
BERGER FRANKLIN M
Non-Executive Director
|
40,000
+inf%
6.75
US$270,000
|
40,000
+inf%
|
6.75
|
US$270,000
|
|
|
2017-12-19 |
2017-12-18 |
B
Purchase
|
Kelly Jeffery W.
|
4,000
+4.1%
5.00
US$20,000
|
4,000
+4.1%
|
5.00
|
US$20,000
|
|
|
2017-12-19 |
2017-12-18 |
B
Purchase
|
BARRETT M JAMES
Large shareholder
|
2,000,000
+56.3%
5.00
US$10,000,000
|
2,000,000
+56.3%
|
5.00
|
US$10,000,000
|
|
|
2017-12-19 |
2017-12-18 |
B
Purchase
|
New Enterprise Associates 12, Limited Partnership
Large shareholder
|
2,000,000
+56.3%
5.00
US$10,000,000
|
2,000,000
+56.3%
|
5.00
|
US$10,000,000
|
|
|
2017-12-19 |
2017-12-18 |
B
Purchase
|
Chhabra Meenu
President and CEO
Executive Director
|
40,000
+391.5%
5.00
US$200,000
|
40,000
+391.5%
|
5.00
|
US$200,000
|
|
|
2017-12-19 |
2017-12-18 |
B
Purchase
|
BERGER FRANKLIN M
|
60,000
+29.1%
5.00
US$300,000
|
60,000
+29.1%
|
5.00
|
US$300,000
|
|
|
2017-03-15 |
2017-03-13 |
S
Sale
|
FMR LLC
See Remark 1
|
25,000
-9.3%
12.94
US$323,500
|
25,000
-9.3%
|
12.94
|
US$323,500
|
|
|
2017-03-13 |
2017-03-10 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
25,000
-8.5%
12.04
US$301,000
|
25,000
-8.5%
|
12.04
|
US$301,000
|
|
|
2017-03-10 |
2017-03-09 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
800
-0.3%
11.96
US$9,568
|
800
-0.3%
|
11.96
|
US$9,568
|
|
|
2017-03-10 |
2017-03-09 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
400
-0.1%
11.91
US$4,764
|
400
-0.1%
|
11.91
|
US$4,764
|
|
|
2017-03-10 |
2017-03-09 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
400
-0.1%
11.86
US$4,744
|
400
-0.1%
|
11.86
|
US$4,744
|
|
|
2017-03-10 |
2017-03-09 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
200
-0.1%
11.78
US$2,356
|
200
-0.1%
|
11.78
|
US$2,356
|
|
|
2017-03-10 |
2017-03-09 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
2,500
-0.8%
11.97
US$29,925
|
2,500
-0.8%
|
11.97
|
US$29,925
|
|
|
2017-03-10 |
2017-03-08 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
25,000
-7.7%
12.10
US$302,500
|
25,000
-7.7%
|
12.10
|
US$302,500
|
|
|
2017-03-08 |
2017-03-07 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
4,897
-1.5%
13.59
US$66,550
|
4,897
-1.5%
|
13.59
|
US$66,550
|
|
|
2017-03-08 |
2017-03-07 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
30,103
-8.4%
12.67
US$381,405
|
30,103
-8.4%
|
12.67
|
US$381,405
|
|
|
2017-03-08 |
2017-03-06 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
25,000
-6.5%
13.31
US$332,750
|
25,000
-6.5%
|
13.31
|
US$332,750
|
|
|
2017-03-06 |
2017-03-03 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
20,000
-5.0%
13.63
US$272,600
|
20,000
-5.0%
|
13.63
|
US$272,600
|
|
|
2017-03-06 |
2017-03-02 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
4,500
-1.1%
14.58
US$65,610
|
4,500
-1.1%
|
14.58
|
US$65,610
|
|
|
2017-03-06 |
2017-03-02 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
20,500
-4.8%
14.03
US$287,615
|
20,500
-4.8%
|
14.03
|
US$287,615
|
|
|
2017-03-02 |
2017-03-01 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
30,000
-6.6%
14.70
US$441,000
|
30,000
-6.6%
|
14.70
|
US$441,000
|
|
|
2017-03-02 |
2017-02-28 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
15,000
-3.2%
14.47
US$217,050
|
15,000
-3.2%
|
14.47
|
US$217,050
|
|
|
2017-02-28 |
2017-02-27 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
15,000
-3.1%
14.65
US$219,750
|
15,000
-3.1%
|
14.65
|
US$219,750
|
|
|
2017-02-28 |
2017-02-24 |
S
Sale
|
FMR LLC
See Remark 1
Large shareholder
|
13,000
-2.6%
14.55
US$189,150
|
13,000
-2.6%
|
14.55
|
US$189,150
|
|
|
2016-12-19 |
2016-12-16 |
B
Purchase
|
BERGER FRANKLIN M
Non-Executive Director
|
14,000
+7.3%
11.52
US$161,342
|
14,000
+7.3%
|
11.52
|
US$161,342
|
|
|
2016-12-19 |
2016-12-15 |
B
Purchase
|
BERGER FRANKLIN M
Non-Executive Director
|
26,000
+15.6%
10.99
US$285,626
|
26,000
+15.6%
|
10.99
|
US$285,626
|
|
|
2016-12-14 |
2016-12-13 |
B
Purchase
|
Cormorant Asset Management, LLC
Large shareholder
|
21,301
+0.6%
10.98
US$233,955
|
21,301
+0.6%
|
10.98
|
US$233,955
|
|