|
2023-12-06 |
2023-12-06 |
B
Compra
|
Consejero no ejecutivo
|
25 679
+46.6%
286,05
815.730 US$
|
25 679
+46.6%
|
286,05
|
815.730 US$
|
|
|
2023-12-06 |
2023-12-05 |
B
Compra
|
Consejero no ejecutivo
|
68 440
-23.2%
204,04
2.908.354 US$
|
68 440
-23.2%
|
204,04
|
2.908.354 US$
|
|
|
2023-12-06 |
2023-12-04 |
B
Compra
|
Consejero no ejecutivo
|
52 605
+4.5%
483,70
1.245.481 US$
|
52 605
+4.5%
|
483,70
|
1.245.481 US$
|
|
|
2023-11-30 |
2023-11-29 |
B
Compra
|
Chief Executive Officer
Consejero ejecutivo
|
4 100
+0.6%
3,51
14.403 US$
|
4 100
+0.6%
|
3,51
|
14.403 US$
|
|
|
2023-11-30 |
2023-11-28 |
B
Compra
|
President
Oficial
|
3 000
+5.2%
3,27
9.812 US$
|
3 000
+5.2%
|
3,27
|
9.812 US$
|
|
|
2023-11-30 |
2023-11-28 |
B
Compra
|
Chief Executive Officer
Consejero ejecutivo
|
900
+0.1%
3,33
2.995 US$
|
900
+0.1%
|
3,33
|
2.995 US$
|
|
|
2023-09-21 |
2023-09-21 |
B
Compra
|
President
Oficial
|
2 900
+5.3%
2,40
6.970 US$
|
2 900
+5.3%
|
2,40
|
6.970 US$
|
|
|
2023-09-21 |
2023-09-20 |
B
Compra
|
President
Oficial
|
600
+1.1%
2,54
1.525 US$
|
600
+1.1%
|
2,54
|
1.525 US$
|
|
|
2023-09-21 |
2023-09-20 |
B
Compra
|
General Counsel & Secretary
Oficial
|
1 500
+8.9%
2,58
3.870 US$
|
1 500
+8.9%
|
2,58
|
3.870 US$
|
|
|
2023-09-21 |
2023-09-20 |
B
Compra
|
Chief Executive Officer
Consejero ejecutivo
|
10 000
+1.5%
2,50
25.042 US$
|
10 000
+1.5%
|
2,50
|
25.042 US$
|
|
|
2023-09-21 |
2023-09-19 |
B
Compra
|
Consejero no ejecutivo
|
2 000
+15.4%
2,37
4.745 US$
|
2 000
+15.4%
|
2,37
|
4.745 US$
|
|
|
2023-09-19 |
2023-09-18 |
B
Compra
|
Consejero no ejecutivo
|
2 500
+23.9%
2,08
5.200 US$
|
2 500
+23.9%
|
2,08
|
5.200 US$
|
|
|
2023-09-19 |
2023-09-18 |
B
Compra
|
Chief Financial Officer
Oficial
|
5 000
+42.1%
2,13
10.672 US$
|
5 000
+42.1%
|
2,13
|
10.672 US$
|
|
|
2023-09-19 |
2023-09-15 |
B
Compra
|
Consejero no ejecutivo
|
500
+5.0%
2,18
1.090 US$
|
500
+5.0%
|
2,18
|
1.090 US$
|
|
|
2023-09-15 |
2023-09-14 |
B
Compra
|
Chief Scientific Officer
Oficial
|
10 000
+85.5%
2,00
20.000 US$
|
10 000
+85.5%
|
2,00
|
20.000 US$
|
|
|
2023-06-16 |
2023-06-16 |
B
Compra
|
Chief Financial Officer
Oficial
|
5 000
+72.7%
2,92
14.600 US$
|
5 000
+72.7%
|
2,92
|
14.600 US$
|
|
|
2023-03-21 |
2023-03-20 |
S
Venta
|
General Counsel & Secretary
Oficial
|
544
-3.0%
3,29
1.788 US$
|
544
-3.0%
|
3,29
|
1.788 US$
|
|
|
2023-03-21 |
2023-03-20 |
S
Venta
|
Chief Executive Officer
Consejero ejecutivo
|
1 119
-0.2%
3,29
3.678 US$
|
1 119
-0.2%
|
3,29
|
3.678 US$
|
|
|
2023-03-21 |
2023-03-20 |
S
Venta
|
President
Oficial
|
872
-1.3%
3,29
2.866 US$
|
872
-1.3%
|
3,29
|
2.866 US$
|
|
|
2023-03-21 |
2023-03-17 |
S
Venta
|
General Counsel & Secretary
Oficial
|
22
-0.1%
5,23
115 US$
|
22
-0.1%
|
5,23
|
115 US$
|
|
|
2023-03-21 |
2023-03-17 |
S
Venta
|
General Counsel & Secretary
Oficial
|
745
-3.9%
4,94
3.677 US$
|
745
-3.9%
|
4,94
|
3.677 US$
|
|
|
2023-03-21 |
2023-03-17 |
S
Venta
|
Chief Executive Officer
Consejero ejecutivo
|
44
-0.0%
5,23
230 US$
|
44
-0.0%
|
5,23
|
230 US$
|
|
|
2023-03-21 |
2023-03-17 |
S
Venta
|
Chief Executive Officer
Consejero ejecutivo
|
1 536
-0.2%
4,93
7.578 US$
|
1 536
-0.2%
|
4,93
|
7.578 US$
|
|
|
2023-03-21 |
2023-03-17 |
S
Venta
|
President
Oficial
|
1
-0.0%
5,25
5 US$
|
1
-0.0%
|
5,25
|
5 US$
|
|
|
2023-03-21 |
2023-03-17 |
S
Venta
|
President
Oficial
|
34
-0.1%
5,23
178 US$
|
34
-0.1%
|
5,23
|
178 US$
|
|
|
2023-03-21 |
2023-03-17 |
S
Venta
|
President
Oficial
|
1 196
-1.7%
4,94
5.902 US$
|
1 196
-1.7%
|
4,94
|
5.902 US$
|
|
|
2023-01-04 |
2022-12-30 |
B
Compra
|
Consejero no ejecutivo
|
1 000
+inf%
6,23
6.225 US$
|
1 000
+inf%
|
6,23
|
6.225 US$
|
|
|
2023-01-04 |
2022-12-30 |
B
Compra
|
Consejero no ejecutivo
|
1 001
+inf%
6,23
6.231 US$
|
1 001
+inf%
|
6,23
|
6.231 US$
|
|
|
2023-01-04 |
2022-12-30 |
B
Compra
|
Consejero no ejecutivo
|
5 000
+100.9%
6,23
31.125 US$
|
5 000
+100.9%
|
6,23
|
31.125 US$
|
|
|
2022-12-06 |
2022-12-02 |
S
Venta
|
President and CEO
Consejero ejecutivo
|
10 890
-10.8%
1,69
18.418 US$
|
10 890
-10.8%
|
1,69
|
18.418 US$
|
|
|
2022-12-06 |
2022-12-02 |
S
Venta
|
Principal Accounting Officer
Oficial
|
1 976
-18.2%
1,69
3.341 US$
|
1 976
-18.2%
|
1,69
|
3.341 US$
|
|
|
2022-12-06 |
2022-12-02 |
S
Venta
|
See Remarks
Oficial
|
3 116
-18.2%
1,69
5.270 US$
|
3 116
-18.2%
|
1,69
|
5.270 US$
|
|
|
2022-12-06 |
2022-12-02 |
S
Venta
|
SVP and General Counsel
Oficial
|
3 116
-18.2%
1,69
5.269 US$
|
3 116
-18.2%
|
1,69
|
5.269 US$
|
|
|
2022-07-06 |
2022-07-05 |
S
Venta
|
President and CEO
Consejero ejecutivo
|
4 584
-4.3%
1,85
8.476 US$
|
4 584
-4.3%
|
1,85
|
8.476 US$
|
|
|
2022-06-06 |
2022-06-03 |
S
Venta
|
SVP and General Counsel
Oficial
|
2 923
-14.6%
1,19
3.492 US$
|
2 923
-14.6%
|
1,19
|
3.492 US$
|
|
|
2022-06-06 |
2022-06-03 |
S
Venta
|
President and CEO
Consejero ejecutivo
|
10 206
-8.8%
1,19
12.192 US$
|
10 206
-8.8%
|
1,19
|
12.192 US$
|
|
|
2022-06-06 |
2022-06-03 |
S
Venta
|
Principal Accounting Officer
Oficial
|
1 806
-14.3%
1,19
2.157 US$
|
1 806
-14.3%
|
1,19
|
2.157 US$
|
|
|
2022-06-06 |
2022-06-03 |
S
Venta
|
See Remarks
Oficial
|
2 887
-14.4%
1,19
3.449 US$
|
2 887
-14.4%
|
1,19
|
3.449 US$
|
|
|
2022-03-30 |
2022-03-28 |
Por favor
Venta prevista
|
President and CEO
Consejero ejecutivo
|
10 715
-8.5%
1,85
19.775 US$
|
10 715
-8.5%
|
1,85
|
19.775 US$
|
|
|
2022-02-07 |
2022-02-03 |
S
Venta
|
Chief Business Officer
Oficial
|
1 958
-3.2%
1,83
3.583 US$
|
1 958
-3.2%
|
1,83
|
3.583 US$
|
|
|
2019-11-29 |
2019-11-27 |
S
Venta
|
New Enterprise Associates 12, Limited Partnership
Gran accionista
|
1 166 755
-21.5%
2,52
2.941.739 US$
|
1 166 755
-21.5%
|
2,52
|
2.941.739 US$
|
|
|
2019-11-29 |
2019-11-26 |
S
Venta
|
New Enterprise Associates 12, Limited Partnership
Gran accionista
|
117 164
-2.1%
2,45
287.134 US$
|
117 164
-2.1%
|
2,45
|
287.134 US$
|
|
|
2019-02-05 |
2019-02-04 |
Por favor
Venta prevista
|
See Remarks
Oficial
|
9 931
-35.0%
2,99
29.700 US$
|
9 931
-35.0%
|
2,99
|
29.700 US$
|
|
|
2019-02-05 |
2019-02-04 |
Por favor
Venta prevista
|
Chief Development Officer
Oficial
|
9 189
-38.1%
2,99
27.480 US$
|
9 189
-38.1%
|
2,99
|
27.480 US$
|
|
|
2019-02-05 |
2019-02-04 |
Por favor
Venta prevista
|
President and CEO
Consejero ejecutivo
|
16 478
-17.0%
2,99
49.305 US$
|
16 478
-17.0%
|
2,99
|
49.305 US$
|
|
|
2019-02-05 |
2019-02-04 |
Por favor
Venta prevista
|
Chief Scientific Officer
Oficial
|
9 514
-38.1%
2,99
28.454 US$
|
9 514
-38.1%
|
2,99
|
28.454 US$
|
|
|
2019-01-30 |
2019-01-29 |
Por favor
Venta prevista
|
See Remarks
Oficial
|
712
-23.5%
3,00
2.136 US$
|
712
-23.5%
|
3,00
|
2.136 US$
|
|
|
2019-01-30 |
2019-01-28 |
Por favor
Venta prevista
|
See Remarks
Oficial
|
1 600
-34.6%
3,00
4.800 US$
|
1 600
-34.6%
|
3,00
|
4.800 US$
|
|
|
2018-10-26 |
2018-10-26 |
B
Compra
|
BERGER FRANKLIN M
Consejero no ejecutivo
|
40 000
+inf%
6,75
270.000 US$
|
40 000
+inf%
|
6,75
|
270.000 US$
|
|
|
2017-12-19 |
2017-12-18 |
B
Compra
|
Kelly Jeffery W.
|
4 000
+4.1%
5,00
20.000 US$
|
4 000
+4.1%
|
5,00
|
20.000 US$
|
|
|
2017-12-19 |
2017-12-18 |
B
Compra
|
BARRETT M JAMES
Gran accionista
|
2 000 000
+56.3%
5,00
10.000.000 US$
|
2 000 000
+56.3%
|
5,00
|
10.000.000 US$
|
|
|
2017-12-19 |
2017-12-18 |
B
Compra
|
New Enterprise Associates 12, Limited Partnership
Gran accionista
|
2 000 000
+56.3%
5,00
10.000.000 US$
|
2 000 000
+56.3%
|
5,00
|
10.000.000 US$
|
|
|
2017-12-19 |
2017-12-18 |
B
Compra
|
Chhabra Meenu
President and CEO
Consejero ejecutivo
|
40 000
+391.5%
5,00
200.000 US$
|
40 000
+391.5%
|
5,00
|
200.000 US$
|
|
|
2017-12-19 |
2017-12-18 |
B
Compra
|
BERGER FRANKLIN M
|
60 000
+29.1%
5,00
300.000 US$
|
60 000
+29.1%
|
5,00
|
300.000 US$
|
|
|
2017-03-15 |
2017-03-13 |
S
Venta
|
FMR LLC
See Remark 1
|
25 000
-9.3%
12,94
323.500 US$
|
25 000
-9.3%
|
12,94
|
323.500 US$
|
|
|
2017-03-13 |
2017-03-10 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
25 000
-8.5%
12,04
301.000 US$
|
25 000
-8.5%
|
12,04
|
301.000 US$
|
|
|
2017-03-10 |
2017-03-09 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
800
-0.3%
11,96
9.568 US$
|
800
-0.3%
|
11,96
|
9.568 US$
|
|
|
2017-03-10 |
2017-03-09 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
400
-0.1%
11,91
4.764 US$
|
400
-0.1%
|
11,91
|
4.764 US$
|
|
|
2017-03-10 |
2017-03-09 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
400
-0.1%
11,86
4.744 US$
|
400
-0.1%
|
11,86
|
4.744 US$
|
|
|
2017-03-10 |
2017-03-09 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
200
-0.1%
11,78
2.356 US$
|
200
-0.1%
|
11,78
|
2.356 US$
|
|
|
2017-03-10 |
2017-03-09 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
2 500
-0.8%
11,97
29.925 US$
|
2 500
-0.8%
|
11,97
|
29.925 US$
|
|
|
2017-03-10 |
2017-03-08 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
25 000
-7.7%
12,10
302.500 US$
|
25 000
-7.7%
|
12,10
|
302.500 US$
|
|
|
2017-03-08 |
2017-03-07 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
4 897
-1.5%
13,59
66.550 US$
|
4 897
-1.5%
|
13,59
|
66.550 US$
|
|
|
2017-03-08 |
2017-03-07 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
30 103
-8.4%
12,67
381.405 US$
|
30 103
-8.4%
|
12,67
|
381.405 US$
|
|
|
2017-03-08 |
2017-03-06 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
25 000
-6.5%
13,31
332.750 US$
|
25 000
-6.5%
|
13,31
|
332.750 US$
|
|
|
2017-03-06 |
2017-03-03 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
20 000
-5.0%
13,63
272.600 US$
|
20 000
-5.0%
|
13,63
|
272.600 US$
|
|
|
2017-03-06 |
2017-03-02 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
4 500
-1.1%
14,58
65.610 US$
|
4 500
-1.1%
|
14,58
|
65.610 US$
|
|
|
2017-03-06 |
2017-03-02 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
20 500
-4.8%
14,03
287.615 US$
|
20 500
-4.8%
|
14,03
|
287.615 US$
|
|
|
2017-03-02 |
2017-03-01 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
30 000
-6.6%
14,70
441.000 US$
|
30 000
-6.6%
|
14,70
|
441.000 US$
|
|
|
2017-03-02 |
2017-02-28 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
15 000
-3.2%
14,47
217.050 US$
|
15 000
-3.2%
|
14,47
|
217.050 US$
|
|
|
2017-02-28 |
2017-02-27 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
15 000
-3.1%
14,65
219.750 US$
|
15 000
-3.1%
|
14,65
|
219.750 US$
|
|
|
2017-02-28 |
2017-02-24 |
S
Venta
|
FMR LLC
See Remark 1
Gran accionista
|
13 000
-2.6%
14,55
189.150 US$
|
13 000
-2.6%
|
14,55
|
189.150 US$
|
|
|
2016-12-19 |
2016-12-16 |
B
Compra
|
BERGER FRANKLIN M
Consejero no ejecutivo
|
14 000
+7.3%
11,52
161.342 US$
|
14 000
+7.3%
|
11,52
|
161.342 US$
|
|
|
2016-12-19 |
2016-12-15 |
B
Compra
|
BERGER FRANKLIN M
Consejero no ejecutivo
|
26 000
+15.6%
10,99
285.626 US$
|
26 000
+15.6%
|
10,99
|
285.626 US$
|
|
|
2016-12-14 |
2016-12-13 |
B
Compra
|
Cormorant Asset Management, LLC
Gran accionista
|
21 301
+0.6%
10,98
233.955 US$
|
21 301
+0.6%
|
10,98
|
233.955 US$
|
|