Kenny Pauline

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2023-09-21	2023-09-20	Proteostasis Therapeutics Inc (PTI)	B Purchase	56,299 +18.2% 439.53 US$1,134,233	56,299 +18.2%	439.53	US$1,134,233
2023-03-21	2023-03-20	Proteostasis Therapeutics Inc (PTI)	S Sale	25,170 +18.1% 420.81 US$1,609,528	25,170 +18.1%	420.81	US$1,609,528
2023-03-21	2023-03-17	Proteostasis Therapeutics Inc (PTI)	S Sale	4,886 -2.5% 213.25 US$4,791,122	4,886 -2.5%	213.25	US$4,791,122
2023-03-21	2023-03-17	Proteostasis Therapeutics Inc (PTI)	S Sale	745 -3.9% 4.94 US$3,677	745 -3.9%	4.94	US$3,677