Wyzga Michael D

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2022-12-06	2022-12-02	Proteostasis Therapeutics Inc (PTI)	S Sale	29,340 +27.3% 103.98 US$3,934,982	29,340 +27.3%	103.98	US$3,934,982
2022-06-06	2022-06-03	Proteostasis Therapeutics Inc (PTI)	S Sale	3,682 -44.3% 339.46 US$4,884,229	3,682 -44.3%	339.46	US$4,884,229