Prelude Therapeutics Inc (PRLD)

Healthcare Pharmaceuticals & Medical Research Biotechnology & Medical Research

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Ticker: PRLD Exchange: NSM

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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale

Past 90 days

Value bought

Value sold

Net insiders buying

Trades (buy and sell)

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Insider and/or position	Nb. shares Price Value	Number of shares	Price	Total value
2023-05-26	2023-05-25	B Purchase	Vaddi Krishna CEO Executive Director	900 +0.1% 5.31 4,779 USD	900 +0.1%	5.31	4,779 USD
2023-05-26	2023-05-24	B Purchase	Vaddi Krishna CEO Executive Director	1,000 +0.1% 5.01 5,011 USD	1,000 +0.1%	5.01	5,011 USD
2023-05-25	2023-05-24	B Purchase	Lim Bryant David Chief Legal Officer, Corp Sec. Officer	2,400 +inf% 5.39 12,936 USD	2,400 +inf%	5.39	12,936 USD
2023-05-25	2023-05-23	B Purchase	Vaddi Krishna CEO Executive Director	11,856 +1.1% 5.63 66,749 USD	11,856 +1.1%	5.63	66,749 USD
2023-05-25	2023-05-23	PP Planned purchase	Chardonnet Laurent Chief Financial Officer Officer	5,000 +13.5% 5.50 27,500 USD	5,000 +13.5%	5.50	27,500 USD
2023-05-24	2023-05-22	B Purchase	ORBIMED ADVISORS LLC Non-Executive Director Large shareholder	869,565 +9.4% 5.75 4,999,999 USD	869,565 +9.4%	5.75	4,999,999 USD
2023-05-24	2023-05-22	B Purchase	Bonita David P Non-Executive Director Large shareholder	869,565 +9.4% 5.75 4,999,999 USD	869,565 +9.4%	5.75	4,999,999 USD
2023-04-06	2023-04-06	S Sale	Huang Jane President, CMO Officer	13,280 -35.4% 6.12 81,274 USD	13,280 -35.4%	6.12	81,274 USD
2022-12-21	2022-12-20	B Purchase	Vaddi Krishna CEO Executive Director	19,188 +18.9% 5.13 98,446 USD	19,188 +18.9%	5.13	98,446 USD
2022-12-12	2022-12-08	PP Planned purchase	Chardonnet Laurent Chief Financial Officer Officer	10,000 +38.7% 4.76 47,600 USD	10,000 +38.7%	4.76	47,600 USD
2022-06-01	2022-06-01	B Purchase	Chardonnet Laurent Chief Financial Officer Officer	10,000 +69.0% 4.23 42,300 USD	10,000 +69.0%	4.23	42,300 USD
2021-12-17	2021-12-15	PS Planned sale	Morosini Deborah EVP, Chief of Clinical Affairs Officer	28,751 -98.5% 13.00 373,763 USD	28,751 -98.5%	13.00	373,763 USD
2021-12-15	2021-12-14	B Purchase	Combs Andrew EVP, Head of Chemistry Officer	4,000 +1.5% 11.60 46,400 USD	4,000 +1.5%	11.60	46,400 USD
2021-12-15	2021-12-13	B Purchase	Combs Andrew EVP, Head of Chemistry Officer	4,000 +1.5% 12.12 48,480 USD	4,000 +1.5%	12.12	48,480 USD
2021-11-18	2021-11-16	PS Planned sale	Morosini Deborah EVP, Chief of Clinical Affairs Officer	400 -47.4% 16.43 6,570 USD	400 -47.4%	16.43	6,570 USD
2021-11-18	2021-11-16	PS Planned sale	Morosini Deborah EVP, Chief of Clinical Affairs Officer	28,351 -97.1% 15.87 449,962 USD	28,351 -97.1%	15.87	449,962 USD
2021-10-06	2021-10-05	PS Planned sale	Mauro David J Chief Medical Officer Officer	1,289 -100.0% 32.06 41,330 USD	1,289 -100.0%	32.06	41,330 USD
2021-10-06	2021-10-05	PS Planned sale	Mauro David J Chief Medical Officer Officer	7,803 -85.8% 31.30 244,257 USD	7,803 -85.8%	31.30	244,257 USD
2021-10-06	2021-10-05	PS Planned sale	Mauro David J Chief Medical Officer Officer	5,908 -39.4% 30.26 178,762 USD	5,908 -39.4%	30.26	178,762 USD
2021-06-09	2021-06-07	PS Planned sale	Mauro David J Chief Medical Officer Officer	12,700 -100.0% 32.73 415,665 USD	12,700 -100.0%	32.73	415,665 USD
2021-06-09	2021-06-07	PS Planned sale	Mauro David J Chief Medical Officer Officer	900 -6.6% 31.62 28,462 USD	900 -6.6%	31.62	28,462 USD
2021-06-09	2021-06-07	PS Planned sale	Mauro David J Chief Medical Officer Officer	1,400 -9.3% 30.35 42,496 USD	1,400 -9.3%	30.35	42,496 USD
2021-05-27	2021-05-25	PS Planned sale	Piper Brian Chief Financial Officer Officer	399 -100.0% 36.09 14,401 USD	399 -100.0%	36.09	14,401 USD
2021-05-27	2021-05-25	PS Planned sale	Piper Brian Chief Financial Officer Officer	1,736 -81.3% 35.45 61,536 USD	1,736 -81.3%	35.45	61,536 USD
2021-05-27	2021-05-25	PS Planned sale	Piper Brian Chief Financial Officer Officer	3,088 -59.1% 34.11 105,338 USD	3,088 -59.1%	34.11	105,338 USD
2021-05-27	2021-05-25	PS Planned sale	Piper Brian Chief Financial Officer Officer	3,110 -37.3% 33.53 104,263 USD	3,110 -37.3%	33.53	104,263 USD
2021-05-11	2021-05-07	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	200 -0.1% 41.85 8,370 USD	200 -0.1%	41.85	8,370 USD
2021-05-11	2021-05-07	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	5,836 -3.3% 41.14 240,090 USD	5,836 -3.3%	41.14	240,090 USD
2021-05-11	2021-05-07	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	3,964 -2.2% 40.30 159,732 USD	3,964 -2.2%	40.30	159,732 USD
2021-05-10	2021-05-05	PS Planned sale	Mauro David J Chief Medical Officer Officer	1,109 -100.0% 41.07 45,545 USD	1,109 -100.0%	41.07	45,545 USD
2021-05-10	2021-05-05	PS Planned sale	Mauro David J Chief Medical Officer Officer	10,476 -90.4% 40.30 422,148 USD	10,476 -90.4%	40.30	422,148 USD
2021-05-10	2021-05-05	PS Planned sale	Mauro David J Chief Medical Officer Officer	3,415 -22.8% 39.36 134,399 USD	3,415 -22.8%	39.36	134,399 USD
2021-04-30	2021-04-29	PS Planned sale	Pierce Christopher EVP and Chief of Business Oper Officer	3,295 -46.8% 40.29 132,765 USD	3,295 -46.8%	40.29	132,765 USD
2021-04-30	2021-04-29	PS Planned sale	Morosini Deborah EVP, Chief of Clinical Affairs Officer	3,223 -87.9% 40.29 129,853 USD	3,223 -87.9%	40.29	129,853 USD
2021-04-29	2021-04-27	PS Planned sale	Mauro David J Chief Medical Officer Officer	1,711 -100.0% 36.11 61,791 USD	1,711 -100.0%	36.11	61,791 USD
2021-04-29	2021-04-27	PS Planned sale	Mauro David J Chief Medical Officer Officer	15,601 -90.1% 35.68 556,580 USD	15,601 -90.1%	35.68	556,580 USD
2021-04-29	2021-04-27	PS Planned sale	Mauro David J Chief Medical Officer Officer	7,688 -30.8% 34.66 266,478 USD	7,688 -30.8%	34.66	266,478 USD
2021-04-21	2021-04-19	PS Planned sale	Mauro David J Chief Medical Officer Officer	4,000 -100.0% 31.27 125,077 USD	4,000 -100.0%	31.27	125,077 USD
2021-04-21	2021-04-19	PS Planned sale	Mauro David J Chief Medical Officer Officer	21,000 -84.0% 30.82 647,273 USD	21,000 -84.0%	30.82	647,273 USD
2021-04-15	2021-04-08	PS Planned sale	Pierce Christopher EVP and Chief of Business Oper Officer	200 -5.1% 40.00 8,000 USD	200 -5.1%	40.00	8,000 USD
2021-04-15	2021-04-08	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	1,669 -1.0% 39.57 66,040 USD	1,669 -1.0%	39.57	66,040 USD
2021-04-15	2021-04-08	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	669 -0.4% 38.97 26,073 USD	669 -0.4%	38.97	26,073 USD
2021-04-15	2021-04-08	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	875 -0.5% 37.72 33,003 USD	875 -0.5%	37.72	33,003 USD
2021-04-15	2021-04-08	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	1,417 -0.8% 36.97 52,387 USD	1,417 -0.8%	36.97	52,387 USD
2021-04-09	2021-04-07	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	200 -0.1% 40.30 8,060 USD	200 -0.1%	40.30	8,060 USD
2021-04-09	2021-04-07	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	6,881 -3.8% 39.63 272,679 USD	6,881 -3.8%	39.63	272,679 USD
2021-04-09	2021-04-07	PS Planned sale	Scherle Peggy Chief Scientific Officer Officer	8,289 -4.4% 39.02 323,405 USD	8,289 -4.4%	39.02	323,405 USD
2021-04-09	2021-04-07	PS Planned sale	Mauro David J Chief Medical Officer Officer	7,083 -100.0% 39.69 281,116 USD	7,083 -100.0%	39.69	281,116 USD
2021-04-09	2021-04-07	PS Planned sale	Mauro David J Chief Medical Officer Officer	8,300 -54.0% 39.03 323,908 USD	8,300 -54.0%	39.03	323,908 USD
2020-09-29	2020-09-29	B Purchase	Combs Andrew EVP, Head of Chemistry Officer	1,000 +0.4% 19.00 19,000 USD	1,000 +0.4%	19.00	19,000 USD
2020-09-29	2020-09-29	B Purchase	Morosini Deborah EVP, Chief of Clinical Affairs Officer	444 +inf% 19.00 8,436 USD	444 +inf%	19.00	8,436 USD
2020-09-29	2020-09-29	B Purchase	Dier Mardi Non-Executive Director	10,000 +inf% 19.00 190,000 USD	10,000 +inf%	19.00	190,000 USD
2020-09-29	2020-09-29	B Purchase	Pierce Christopher EVP and Chief of Business Oper Officer	3,750 +inf% 19.00 71,250 USD	3,750 +inf%	19.00	71,250 USD
2020-09-29	2020-09-25	B Purchase	ORBIMED ADVISORS LLC Non-Executive Director Large shareholder	710,500 +343.4% 19.00 13,499,500 USD	710,500 +343.4%	19.00	13,499,500 USD
2020-09-29	2020-09-25	B Purchase	ORBIMED ADVISORS LLC Non-Executive Director Large shareholder	526,300 +inf% 19.00 9,999,700 USD	526,300 +inf%	19.00	9,999,700 USD