Piper Brian

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2021-05-27	2021-05-25	Prelude Therapeutics Inc (PRLD)	PlS Planned sale	23,491 -23.6% 399.64 US$932,277	23,491 -23.6%	399.64	US$932,277
2021-05-27	2021-05-25	Prelude Therapeutics Inc (PRLD)	PlS Planned sale	7,288 +27.5% 51.24 US$4,717,383	7,288 +27.5%	51.24	US$4,717,383
2021-05-27	2021-05-25	Prelude Therapeutics Inc (PRLD)	PlS Planned sale	5,153 +39.4% 40.92 US$1,045,380	5,153 +39.4%	40.92	US$1,045,380
2021-05-27	2021-05-25	Prelude Therapeutics Inc (PRLD)	PlS Planned sale	3,110 -37.3% 33.53 US$104,263	3,110 -37.3%	33.53	US$104,263