30% off. Use code SUMMERSALE30 at checkout for 30% off for 12 months on Plus, Pro and Premium subscriptions. Subscribe now

Ionis Pharmaceuticals Inc (IONS)

Over the last 90 days, Ionis Pharmaceuticals Inc. has seen significant insider selling, with a net value of -$8.6 million. Executives have been net sellers, contributing to a negative net insider count. Notable transactions include large proposed and planned sales by directors and officers, totaling millions of dollars.
Stock chart
Ticker: IONS Exchange: NSM


Loading...
Purchase Sale Planned purchase Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
BERTHELSEN SPENCER R
2 sales — total 200,000 USD
Planned sale 15 Jun 2026
Value US$4,881,865.82 | Price 48.23 | Shares 22,800
Proposed sale 15 Jun 2026
Value US$2,348,265.92 | Price 265.26 | Shares 55,374
Planned sale 12 Jun 2026
Value US$1,548,912.89 | Price 160.41 | Shares 99,880
Planned sale 12 Jun 2026
Value US$4,173,798.75 | Price 467.01 | Shares 57,058
Proposed sale 12 Jun 2026
Value US$100,000.00 | Price 73.41 | Shares 1,000
Planned sale 1 Jun 2026
Value US$605,360.00 | Price 75.67 | Shares 8,000
Proposed sale 1 Jun 2026
Value US$605,360.00 | Price 75.67 | Shares 8,000
Planned sale 14 May 2026
Value US$253,347.35 | Price 78.68 | Shares 3,220
Planned sale 13 May 2026
Value US$102,665.11 | Price 78.01 | Shares 1,316
Proposed sale 13 May 2026
Value US$7,801,300.00 | Price 78.01 | Shares 100,000
Planned sale 4 May 2026
Value US$1,343,934.21 | Price 75.58 | Shares 17,781
Planned sale 4 May 2026
Value US$4,457,292.02 | Price 74.90 | Shares 59,508
Proposed sale 4 May 2026
Value US$4,345,680.00 | Price 80.00 | Shares 54,321
Planned sale 1 May 2026
Value US$106,534.23 | Price 74.45 | Shares 1,431
Planned sale 1 May 2026
Value US$636,704.04 | Price 73.35 | Shares 8,680
Planned sale 28 Apr 2026
Value US$116,726.80 | Price 71.79 | Shares 1,626
Proposed sale 28 Apr 2026
Value US$116,727.00 | Price 71.79 | Shares 1,626
Sale 16 Apr 2026
Value US$73,015.87 | Price 75.04 | Shares 973
Proposed sale 16 Apr 2026
Value US$73,362.15 | Price 75.40 | Shares 973
Sale 16 Apr 2026
Value US$368,488.24 | Price 75.17 | Shares 4,902
Proposed sale 16 Apr 2026
Value US$369,600.09 | Price 75.40 | Shares 4,902
Sale 16 Apr 2026
Value US$418,952.64 | Price 74.56 | Shares 5,619
Proposed sale 16 Apr 2026
Value US$423,659.67 | Price 75.40 | Shares 5,619
Planned sale 15 Apr 2026
Value US$41,101.98 | Price 76.97 | Shares 534
Planned sale 15 Apr 2026
Value US$340,264.54 | Price 76.19 | Shares 4,466
Planned sale 2 Apr 2026
Value US$458,613.33 | Price 74.05 | Shares 6,193
Planned sale 1 Apr 2026
Value US$168,314.06 | Price 75.95 | Shares 2,216
Planned sale 1 Apr 2026
Value US$1,517,987.82 | Price 75.50 | Shares 20,105
Proposed sale 19 Mar 2026
Value US$412,486.00 | Price 70.97 | Shares 5,812
Planned sale 19 Mar 2026
Value US$412,486.36 | Price 70.97 | Shares 5,812
Proposed sale 19 Mar 2026
Value US$412,486.00 | Price 70.97 | Shares 5,812
Planned sale 17 Mar 2026
Value US$744,661.60 | Price 73.21 | Shares 10,172
Planned sale 16 Mar 2026
Value US$686,901.60 | Price 72.77 | Shares 9,440
Planned sale 16 Mar 2026
Value US$14,882,112.65 | Price 72.38 | Shares 205,608
Proposed sale 16 Mar 2026
Value US$16,284,212.00 | Price 72.31 | Shares 225,200
Planned sale 10 Mar 2026
Value US$1,227,361.80 | Price 76.30 | Shares 16,086
Planned sale 10 Mar 2026
Value US$1,599,962.88 | Price 75.50 | Shares 21,191
Proposed sale 10 Mar 2026
Value US$4,402,296.00 | Price 75.57 | Shares 58,253
Planned sale 10 Mar 2026
Value US$1,342,909.25 | Price 76.34 | Shares 17,591
Planned sale 10 Mar 2026
Value US$1,246,234.94 | Price 75.47 | Shares 16,512
Planned sale 9 Mar 2026
Value US$763,662.37 | Price 75.25 | Shares 10,148
Proposed sale 9 Mar 2026
Value US$994,612.00 | Price 75.25 | Shares 13,217
Planned sale 9 Mar 2026
Value US$127,281.77 | Price 75.58 | Shares 1,684
Planned sale 9 Mar 2026
Value US$8,850,641.83 | Price 75.26 | Shares 117,604
Planned sale 9 Mar 2026
Value US$547,087.40 | Price 74.11 | Shares 7,382
Planned sale 4 Mar 2026
Value US$16,080.00 | Price 80.00 | Shares 201
Planned sale 4 Mar 2026
Value US$19,040.00 | Price 80.00 | Shares 238
Planned sale 4 Mar 2026
Value US$16,000.00 | Price 80.00 | Shares 200
Proposed sale 3 Mar 2026
Value US$5,469,600.00 | Price 79.50 | Shares 68,800
Planned sale 3 Mar 2026
Value US$81,203.00 | Price 80.80 | Shares 1,005
Planned sale 3 Mar 2026
Value US$1,166,814.00 | Price 79.88 | Shares 14,608
Planned sale 3 Mar 2026
Value US$3,106,411.21 | Price 79.11 | Shares 39,265
Planned sale 3 Mar 2026
Value US$2,916.36 | Price 81.01 | Shares 36
Planned sale 3 Mar 2026
Value US$167,891.70 | Price 80.41 | Shares 2,088
Planned sale 3 Mar 2026
Value US$325,058.56 | Price 79.36 | Shares 4,096
Proposed sale 3 Mar 2026
Value US$325,059.00 | Price 79.36 | Shares 4,096
Planned sale 3 Mar 2026
Value US$61,031.94 | Price 80.84 | Shares 755
Planned sale 3 Mar 2026
Value US$402,394.97 | Price 80.00 | Shares 5,030
Planned sale 3 Mar 2026
Value US$1,133,005.92 | Price 79.12 | Shares 14,321
Proposed sale 3 Mar 2026
Value US$3,101,613.00 | Price 79.50 | Shares 39,014
Planned sale 3 Mar 2026
Value US$66,832.81 | Price 80.33 | Shares 832
Proposed sale 3 Mar 2026
Value US$1,920,000.00 | Price 80.00 | Shares 24,000
Planned sale 3 Mar 2026
Value US$81,787.82 | Price 80.82 | Shares 1,012
Planned sale 3 Mar 2026
Value US$543,486.03 | Price 80.00 | Shares 6,794
Planned sale 3 Mar 2026
Value US$1,070,907.52 | Price 79.17 | Shares 13,526
Proposed sale 3 Mar 2026
Value US$5,035,928.00 | Price 77.07 | Shares 65,345
Planned sale 3 Mar 2026
Value US$64,771.12 | Price 80.76 | Shares 802
Planned sale 3 Mar 2026
Value US$1,013,409.65 | Price 79.88 | Shares 12,687
Planned sale 3 Mar 2026
Value US$5,663,488.40 | Price 79.10 | Shares 71,600
Proposed sale 3 Mar 2026
Value US$7,056,227.00 | Price 82.93 | Shares 85,089
Proposed sale 3 Mar 2026
Value US$655,840.00 | Price 80.00 | Shares 8,198
Planned sale 13 Feb 2026
Value US$509,402.90 | Price 82.07 | Shares 6,207
Planned sale 13 Feb 2026
Value US$769,511.05 | Price 81.56 | Shares 9,435
Proposed sale 13 Feb 2026
Value US$1,277,169.00 | Price 81.65 | Shares 15,642
Planned sale 11 Feb 2026
Value US$413,588.50 | Price 82.72 | Shares 5,000
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value
Number of shares Price Value Details
2026-06-16 2026-06-15 PlS Planned sale Non-Executive Director
22,800 -17.7%
48.23
US$4,881,866
22,800 -17.7% 48.23 US$4,881,866
2026-06-15 2026-06-15 PrS Proposed sale

Director

Non-Executive Director
55,374
265.26
US$2,348,266
55,374 265.26 US$2,348,266
2026-06-16 2026-06-12 PlS Planned sale

EVP, Chief Development Officer

Officer
99,880 +32.5%
160.41
US$1,548,913
99,880 +32.5% 160.41 US$1,548,913
2026-06-16 2026-06-12 PlS Planned sale

EVP, Chief Development Officer

Officer
1,000 -49.2%
73.09
US$100,000
1,000 -49.2% 73.09 US$100,000
2026-06-12 2026-06-12 PrS Proposed sale

Officer

Officer
1,000
73.41
US$100,000
1,000 73.41 US$100,000
2026-06-03 2026-06-01 PlS Planned sale Non-Executive Director
8,000 -4.9%
75.67
US$605,360
8,000 -4.9% 75.67 US$605,360
2026-06-01 2026-06-01 PrS Proposed sale

Director

Non-Executive Director
8,000
75.67
US$605,360
8,000 75.67 US$605,360
2026-05-15 2026-05-14 PlS Planned sale

Chief Executive Officer

Executive Director
3,220 -1.3%
78.68
US$253,347
3,220 -1.3% 78.68 US$253,347
2026-05-15 2026-05-13 PlS Planned sale

Chief Executive Officer

Executive Director
1,316 -0.5%
78.01
US$102,665
1,316 -0.5% 78.01 US$102,665
2026-05-13 2026-05-13 PrS Proposed sale

Officer

Officer
100,000
78.01
US$7,801,300
100,000 78.01 US$7,801,300
2026-05-06 2026-05-04 PlS Planned sale Non-Executive Director
17,781 -32.9%
75.58
US$1,343,934
17,781 -32.9% 75.58 US$1,343,934
2026-05-06 2026-05-04 PlS Planned sale Non-Executive Director
59,508 -52.4%
74.90
US$4,457,292
59,508 -52.4% 74.90 US$4,457,292
2026-05-04 2026-05-04 PrS Proposed sale

Director

Non-Executive Director
54,321
80.00
US$4,345,680
54,321 80.00 US$4,345,680
2026-05-05 2026-05-01 PlS Planned sale Non-Executive Director
1,431 -11.5%
74.45
US$106,534
1,431 -11.5% 74.45 US$106,534
2026-05-05 2026-05-01 PlS Planned sale Non-Executive Director
8,680 -41.1%
73.35
US$636,704
8,680 -41.1% 73.35 US$636,704
2026-04-30 2026-04-28 PlS Planned sale

EVP, Chief Business Officer

Officer
1,626 -3.5%
71.79
US$116,727
1,626 -3.5% 71.79 US$116,727
2026-04-28 2026-04-28 PrS Proposed sale

Officer

Officer
1,626
71.79
US$116,727
1,626 71.79 US$116,727
2026-04-17 2026-04-16 S Sale

EVP, Corp and Development Ops

Officer
973 -1.4%
75.04
US$73,016
973 -1.4% 75.04 US$73,016
2026-04-17 2026-04-16 S Sale

EVP, Chf GL Pdt Str Ofcr

Officer
4,902 -17.1%
75.17
US$368,488
4,902 -17.1% 75.17 US$368,488
2026-04-17 2026-04-16 S Sale

EVP, Chief Business Officer

Officer
5,619 -10.8%
74.56
US$418,953
5,619 -10.8% 74.56 US$418,953
2026-04-16 2026-04-16 PrS Proposed sale

Officer

Officer
4,902
75.40
US$369,600
4,902 75.40 US$369,600
2026-04-16 2026-04-16 PrS Proposed sale

Officer

Officer
973
75.40
US$73,362
973 75.40 US$73,362
2026-04-16 2026-04-16 PrS Proposed sale

Officer

Officer
5,619
75.40
US$423,660
5,619 75.40 US$423,660
2026-04-17 2026-04-15 PlS Planned sale Non-Executive Director
534 -1.0%
76.97
US$41,102
534 -1.0% 76.97 US$41,102
2026-04-17 2026-04-15 PlS Planned sale Non-Executive Director
4,466 -7.9%
76.19
US$340,265
4,466 -7.9% 76.19 US$340,265
2026-04-02 2026-04-02 PlS Planned sale

EVP, Chief Human Resources Ofc

Officer
6,193 -27.5%
74.05
US$458,613
6,193 -27.5% 74.05 US$458,613
2026-04-02 2026-04-01 PlS Planned sale Non-Executive Director
2,216 -16.7%
75.95
US$168,314
2,216 -16.7% 75.95 US$168,314
2026-04-02 2026-04-01 PlS Planned sale Non-Executive Director
20,105 -60.3%
75.50
US$1,517,988
20,105 -60.3% 75.50 US$1,517,988
2026-03-24 2026-03-19 PrS Proposed sale

Officer

Officer
5,812
70.97
US$412,486
5,812 70.97 US$412,486
2026-03-23 2026-03-19 PlS Planned sale

EVP, Chf Clinical Develop Ofcr

Officer
5,812 -8.3%
70.97
US$412,486
5,812 -8.3% 70.97 US$412,486
2026-03-19 2026-03-19 PrS Proposed sale

Officer

Officer
5,812
70.97
US$412,486
5,812 70.97 US$412,486
2026-03-18 2026-03-17 PlS Planned sale

EVP, Finance & CFO

Officer
10,172 -11.0%
73.21
US$744,662
10,172 -11.0% 73.21 US$744,662
2026-03-18 2026-03-16 PlS Planned sale

EVP, Finance & CFO

Officer
9,440 -9.2%
72.77
US$686,902
9,440 -9.2% 72.77 US$686,902
2026-03-18 2026-03-16 PlS Planned sale

EVP, Finance & CFO

Officer
205,608 -66.8%
72.38
US$14,882,113
205,608 -66.8% 72.38 US$14,882,113
2026-03-16 2026-03-16 PrS Proposed sale

Officer

Officer
225,200
72.31
US$16,284,212
225,200 72.31 US$16,284,212
2026-03-11 2026-03-10 PlS Planned sale

EVP, Chf GL Pdt Str Ofcr

Officer
16,086 -57.9%
76.30
US$1,227,362
16,086 -57.9% 76.30 US$1,227,362
2026-03-11 2026-03-10 PlS Planned sale

EVP, Chf GL Pdt Str Ofcr

Officer
21,191 -43.3%
75.50
US$1,599,963
21,191 -43.3% 75.50 US$1,599,963
2026-03-11 2026-03-10 PlS Planned sale

Chief Executive Officer

Executive Director
17,591 -6.8%
76.34
US$1,342,909
17,591 -6.8% 76.34 US$1,342,909
2026-03-11 2026-03-10 PlS Planned sale

Chief Executive Officer

Executive Director
16,512 -6.0%
75.47
US$1,246,235
16,512 -6.0% 75.47 US$1,246,235
2026-03-10 2026-03-10 PrS Proposed sale

Director

Non-Executive Director
58,253
75.57
US$4,402,296
58,253 75.57 US$4,402,296
2026-03-11 2026-03-09 PlS Planned sale

EVP CLO & General Counsel

Officer
10,148 -14.0%
75.25
US$763,662
10,148 -14.0% 75.25 US$763,662
2026-03-11 2026-03-09 PlS Planned sale

Chief Executive Officer

Executive Director
1,684 -0.7%
75.58
US$127,282
1,684 -0.7% 75.58 US$127,282
2026-03-11 2026-03-09 PlS Planned sale

Chief Executive Officer

Executive Director
117,604 -32.5%
75.26
US$8,850,642
117,604 -32.5% 75.26 US$8,850,642
2026-03-11 2026-03-09 PlS Planned sale

Chief Executive Officer

Executive Director
7,382 -2.0%
74.11
US$547,087
7,382 -2.0% 74.11 US$547,087
2026-03-09 2026-03-09 PrS Proposed sale

Officer

Officer
13,217
75.25
US$994,612
13,217 75.25 US$994,612
2026-03-05 2026-03-04 PlS Planned sale

EVP, Chief Business Officer

Officer
201 -4.4%
80.00
US$16,080
201 -4.4% 80.00 US$16,080
2026-03-05 2026-03-04 PlS Planned sale

EVP, Chief Business Officer

Officer
238 -5.2%
80.00
US$19,040
238 -5.2% 80.00 US$19,040
2026-03-05 2026-03-04 PlS Planned sale Non-Executive Director
200 -0.5%
80.00
US$16,000
200 -0.5% 80.00 US$16,000
2026-03-31 2026-03-03 PrS Proposed sale

Director

Non-Executive Director
68,800
79.50
US$5,469,600
68,800 79.50 US$5,469,600
2026-03-05 2026-03-03 PlS Planned sale

EVP, Chief Business Officer

Officer
36 -0.8%
81.01
US$2,916
36 -0.8% 81.01 US$2,916
2026-03-05 2026-03-03 PlS Planned sale

EVP, Chief Business Officer

Officer
2,088 -32.3%
80.41
US$167,892
2,088 -32.3% 80.41 US$167,892
2026-03-05 2026-03-03 PlS Planned sale

EVP, Chief Business Officer

Officer
4,096 -9.0%
79.36
US$325,059
4,096 -9.0% 79.36 US$325,059
2026-03-05 2026-03-03 PlS Planned sale

EVP, Chief Human Resources Ofc

Officer
755 -3.2%
80.84
US$61,032
755 -3.2% 80.84 US$61,032
2026-03-05 2026-03-03 PlS Planned sale

EVP, Chief Human Resources Ofc

Officer
5,030 -17.8%
80.00
US$402,395
5,030 -17.8% 80.00 US$402,395
2026-03-05 2026-03-03 PlS Planned sale

EVP, Chief Human Resources Ofc

Officer
14,321 -33.6%
79.12
US$1,133,006
14,321 -33.6% 79.12 US$1,133,006
2026-03-05 2026-03-03 PlS Planned sale Non-Executive Director
832 -2.2%
80.33
US$66,833
832 -2.2% 80.33 US$66,833
2026-03-05 2026-03-03 PlS Planned sale Non-Executive Director
1,005 -20.9%
80.80
US$81,203
1,005 -20.9% 80.80 US$81,203
2026-03-05 2026-03-03 PlS Planned sale Non-Executive Director
14,608 -75.2%
79.88
US$1,166,814
14,608 -75.2% 79.88 US$1,166,814
2026-03-05 2026-03-03 PlS Planned sale Non-Executive Director
39,265 -66.9%
79.11
US$3,106,411
39,265 -66.9% 79.11 US$3,106,411
2026-03-05 2026-03-03 PlS Planned sale Non-Executive Director
1,012 -8.4%
80.82
US$81,788
1,012 -8.4% 80.82 US$81,788
2026-03-05 2026-03-03 PlS Planned sale Non-Executive Director
6,794 -36.1%
80.00
US$543,486
6,794 -36.1% 80.00 US$543,486
2026-03-05 2026-03-03 PlS Planned sale Non-Executive Director
13,526 -41.8%
79.17
US$1,070,908
13,526 -41.8% 79.17 US$1,070,908
2026-03-05 2026-03-03 PlS Planned sale

EVP, Chief Scientific Officer

Officer
802 -1.0%
80.76
US$64,771
802 -1.0% 80.76 US$64,771
2026-03-05 2026-03-03 PlS Planned sale

EVP, Chief Scientific Officer

Officer
12,687 -13.5%
79.88
US$1,013,410
12,687 -13.5% 79.88 US$1,013,410
2026-03-05 2026-03-03 PlS Planned sale

EVP, Chief Scientific Officer

Officer
71,600 -43.2%
79.10
US$5,663,488
71,600 -43.2% 79.10 US$5,663,488
2026-03-03 2026-03-03 PrS Proposed sale

Director

Non-Executive Director
24,000
80.00
US$1,920,000
24,000 80.00 US$1,920,000
2026-03-03 2026-03-03 PrS Proposed sale

Officer

Officer
85,089
82.93
US$7,056,227
85,089 82.93 US$7,056,227
2026-03-03 2026-03-03 PrS Proposed sale

Officer

Officer
4,096
79.36
US$325,059
4,096 79.36 US$325,059
2026-03-03 2026-03-03 PrS Proposed sale

Officer

Officer
8,198
80.00
US$655,840
8,198 80.00 US$655,840
2026-03-03 2026-03-03 PrS Proposed sale

Director

Non-Executive Director
65,345
77.07
US$5,035,928
65,345 77.07 US$5,035,928
2026-03-03 2026-03-03 PrS Proposed sale

Officer

Officer
39,014
79.50
US$3,101,613
39,014 79.50 US$3,101,613
2026-02-13 2026-02-13 PlS Planned sale

EVP Research

Officer
6,207 -16.2%
82.07
US$509,403
6,207 -16.2% 82.07 US$509,403
2026-02-13 2026-02-13 PlS Planned sale

EVP Research

Officer
9,435 -19.8%
81.56
US$769,511
9,435 -19.8% 81.56 US$769,511
2026-02-13 2026-02-13 PrS Proposed sale

Officer

Officer
15,642
81.65
US$1,277,169
15,642 81.65 US$1,277,169
2026-02-13 2026-02-11 PlS Planned sale Non-Executive Director
5,000 -8.2%
82.72
US$413,588
5,000 -8.2% 82.72 US$413,588