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Ticker: APLS Exchange: NSM


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Purchase Sale Planned purchase Planned sale Net purchase Net sale
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value
Number of shares Price Total value Details
Aug. 18, 2022 Aug. 17, 2022 PS Planned sale

DeLong Mark Jeffrey

Senior Vice President

Officer
5,000 -14.6%
69.50
347,500 USD
5,000 -14.6% 69.50 347,500 USD
Aug. 16, 2022 Aug. 15, 2022 PS Planned sale

Townsend Adam J.

Chief Commercial Officer

Officer
12,500 -22.6%
69.00
862,500 USD
12,500 -22.6% 69.00 862,500 USD
Aug. 16, 2022 Aug. 15, 2022 PS Planned sale

Machiels Alec

Non-Executive Director
1,250 -0.5%
67.21
84,013 USD
1,250 -0.5% 67.21 84,013 USD
Aug. 12, 2022 Aug. 11, 2022 PS Planned sale

Townsend Adam J.

Chief Commercial Officer

Officer
12,500 -22.6%
67.00
837,500 USD
12,500 -22.6% 67.00 837,500 USD
Aug. 12, 2022 Aug. 11, 2022 PS Planned sale

DeLong Mark Jeffrey

Senior Vice President

Officer
5,000 -14.6%
67.00
335,000 USD
5,000 -14.6% 67.00 335,000 USD
Aug. 12, 2022 Aug. 11, 2022 S Sale

Dunlop A. Sinclair

Non-Executive Director
30,000 -10.5%
65.63
1,968,900 USD
30,000 -10.5% 65.63 1,968,900 USD
Aug. 9, 2022 Aug. 8, 2022 PS Planned sale

DeLong Mark Jeffrey

Senior Vice President

Officer
5,000 -14.6%
64.50
322,500 USD
5,000 -14.6% 64.50 322,500 USD
Aug. 9, 2022 Aug. 8, 2022 PS Planned sale

Townsend Adam J.

Chief Commercial Officer

Officer
12,500 -22.6%
65.00
812,500 USD
12,500 -22.6% 65.00 812,500 USD
Aug. 9, 2022 Aug. 8, 2022 PS Planned sale

Deschatelets Pascal

Chief Scientific Officer

Officer
12,000 -1.3%
62.50
750,000 USD
12,000 -1.3% 62.50 750,000 USD
Aug. 8, 2022 Aug. 4, 2022 PS Planned sale

DeLong Mark Jeffrey

Senior Vice President

Officer
5,000 -14.6%
62.00
310,000 USD
5,000 -14.6% 62.00 310,000 USD
Aug. 8, 2022 Aug. 4, 2022 PS Planned sale

DeLong Mark Jeffrey

Senior Vice President

Officer
5,000 -12.7%
59.50
297,500 USD
5,000 -12.7% 59.50 297,500 USD
Aug. 4, 2022 Aug. 3, 2022 PS Planned sale

Townsend Adam J.

Chief Commercial Officer

Officer
5,000 -11.7%
56.43
282,150 USD
5,000 -11.7% 56.43 282,150 USD
Aug. 2, 2022 Aug. 1, 2022 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
2,500 -2.3%
55.99
139,975 USD
2,500 -2.3% 55.99 139,975 USD
July 28, 2022 July 27, 2022 PS Planned sale

DeLong Mark Jeffrey

Senior Vice President

Officer
5,000 -14.6%
57.00
285,000 USD
5,000 -14.6% 57.00 285,000 USD
July 21, 2022 July 19, 2022 PS Planned sale

DeLong Mark Jeffrey

Senior Vice President

Officer
5,000 -14.6%
56.42
282,100 USD
5,000 -14.6% 56.42 282,100 USD
July 18, 2022 July 15, 2022 PS Planned sale

Machiels Alec

Non-Executive Director
1,250 -0.5%
46.33
57,913 USD
1,250 -0.5% 46.33 57,913 USD
July 12, 2022 July 11, 2022 PS Planned sale

Townsend Adam J.

Chief Commercial Officer

Officer
5,000 -10.4%
48.42
242,100 USD
5,000 -10.4% 48.42 242,100 USD
July 12, 2022 July 8, 2022 PS Planned sale

Deschatelets Pascal

Chief Scientific Officer

Officer
12,000 -1.3%
47.95
575,400 USD
12,000 -1.3% 47.95 575,400 USD
June 29, 2022 June 27, 2022 S Sale

Dunlop A. Sinclair

Non-Executive Director
1,341 -50.0%
46.79
62,743 USD
1,341 -50.0% 46.79 62,743 USD
June 24, 2022 June 23, 2022 S Sale

Dunlop A. Sinclair

Non-Executive Director
15,000 -5.0%
45.00
675,000 USD
15,000 -5.0% 45.00 675,000 USD
June 23, 2022 June 22, 2022 S Sale

Watson David O.

General Counsel

Officer
10,000 -8.0%
44.51
445,140 USD
10,000 -8.0% 44.51 445,140 USD
June 22, 2022 June 17, 2022 S Sale

Brown Victoria L.

Program Team Lead

Officer
2,698 -9.7%
45.00
121,410 USD
2,698 -9.7% 45.00 121,410 USD
June 21, 2022 June 16, 2022 S Sale

DeLong Mark Jeffrey

Senior Vice President

Officer
10,000 -25.5%
41.79
417,850 USD
10,000 -25.5% 41.79 417,850 USD
June 17, 2022 June 15, 2022 PS Planned sale

Machiels Alec

Non-Executive Director
1,250 -0.5%
39.29
49,113 USD
1,250 -0.5% 39.29 49,113 USD
June 9, 2022 June 8, 2022 PS Planned sale

Deschatelets Pascal

Chief Scientific Officer

Officer
12,000 -1.3%
44.09
529,080 USD
12,000 -1.3% 44.09 529,080 USD
June 2, 2022 June 1, 2022 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
2,500 -2.2%
41.78
104,450 USD
2,500 -2.2% 41.78 104,450 USD
May 31, 2022 May 27, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
10,000 -19.9%
43.00
430,000 USD
10,000 -19.9% 43.00 430,000 USD
May 17, 2022 May 16, 2022 PS Planned sale

Machiels Alec

Non-Executive Director
1,250 -0.5%
39.18
48,975 USD
1,250 -0.5% 39.18 48,975 USD
May 3, 2022 May 2, 2022 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
2,500 -2.2%
43.56
108,900 USD
2,500 -2.2% 43.56 108,900 USD
May 2, 2022 April 29, 2022 PS Planned sale

Deschatelets Pascal

Chief Scientific Officer

Officer
4,000 -0.4%
44.43
177,720 USD
4,000 -0.4% 44.43 177,720 USD
April 27, 2022 April 25, 2022 PS Planned sale

Watson David O.

General Counsel

Officer
5,000 -3.8%
50.00
250,000 USD
5,000 -3.8% 50.00 250,000 USD
April 22, 2022 April 20, 2022 PS Planned sale

DeLong Mark Jeffrey

Senior Vice President

Officer
7,000 -19.7%
52.53
367,710 USD
7,000 -19.7% 52.53 367,710 USD
April 18, 2022 April 14, 2022 PS Planned sale

Machiels Alec

Non-Executive Director
1,250 -0.5%
50.90
63,625 USD
1,250 -0.5% 50.90 63,625 USD
April 6, 2022 April 5, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
609 -1.2%
60.09
36,593 USD
609 -1.2% 60.09 36,593 USD
April 5, 2022 April 4, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
1,249 -2.3%
57.81
72,198 USD
1,249 -2.3% 57.81 72,198 USD
April 5, 2022 April 4, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
1,437 -2.6%
56.86
81,714 USD
1,437 -2.6% 56.86 81,714 USD
April 5, 2022 April 4, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
818 -1.5%
55.84
45,677 USD
818 -1.5% 55.84 45,677 USD
April 4, 2022 April 1, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
11,496 -18.0%
55.05
632,855 USD
11,496 -18.0% 55.05 632,855 USD
March 17, 2022 March 15, 2022 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
375 -0.3%
39.57
14,839 USD
375 -0.3% 39.57 14,839 USD
March 17, 2022 March 15, 2022 PS Planned sale

Machiels Alec

Non-Executive Director
1,250 -0.5%
39.57
49,463 USD
1,250 -0.5% 39.57 49,463 USD
March 2, 2022 March 1, 2022 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
375 -0.3%
43.53
16,324 USD
375 -0.3% 43.53 16,324 USD
Feb. 16, 2022 Feb. 15, 2022 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
375 -0.4%
45.43
17,036 USD
375 -0.4% 45.43 17,036 USD
Feb. 16, 2022 Feb. 15, 2022 PS Planned sale

Machiels Alec

Non-Executive Director
1,250 -0.2%
45.43
56,788 USD
1,250 -0.2% 45.43 56,788 USD
Feb. 14, 2022 Feb. 11, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
1,666 -3.1%
46.80
77,969 USD
1,666 -3.1% 46.80 77,969 USD
Feb. 14, 2022 Feb. 10, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
10,000 -15.8%
50.00
500,000 USD
10,000 -15.8% 50.00 500,000 USD
Feb. 10, 2022 Feb. 8, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
10,000 -15.7%
45.00
450,000 USD
10,000 -15.7% 45.00 450,000 USD
Feb. 2, 2022 Feb. 1, 2022 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
375 -0.4%
40.58
15,218 USD
375 -0.4% 40.58 15,218 USD
Feb. 1, 2022 Jan. 31, 2022 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
1,233 -2.2%
38.47
47,434 USD
1,233 -2.2% 38.47 47,434 USD
Jan. 19, 2022 Jan. 14, 2022 PS Planned sale

Machiels Alec

Non-Executive Director
1,250 -0.2%
40.56
50,700 USD
1,250 -0.2% 40.56 50,700 USD
Jan. 19, 2022 Jan. 14, 2022 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
375 -0.5%
40.56
15,210 USD
375 -0.5% 40.56 15,210 USD
Jan. 4, 2022 Jan. 3, 2022 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
375 -0.5%
47.31
17,741 USD
375 -0.5% 47.31 17,741 USD
Dec. 23, 2021 Dec. 22, 2021 S Sale

Watson David O.

General Counsel

Officer
300 -0.3%
48.58
14,573 USD
300 -0.3% 48.58 14,573 USD
Dec. 23, 2021 Dec. 22, 2021 S Sale

Watson David O.

General Counsel

Officer
5,097 -4.5%
47.86
243,917 USD
5,097 -4.5% 47.86 243,917 USD
Dec. 23, 2021 Dec. 22, 2021 S Sale

Watson David O.

General Counsel

Officer
5,174 -4.7%
47.72
246,883 USD
5,174 -4.7% 47.72 246,883 USD
Dec. 17, 2021 Dec. 15, 2021 PS Planned sale

Machiels Alec

Non-Executive Director
3,000 -0.4%
42.88
128,640 USD
3,000 -0.4% 42.88 128,640 USD
Dec. 17, 2021 Dec. 15, 2021 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
375 -0.5%
42.88
16,080 USD
375 -0.5% 42.88 16,080 USD
Dec. 3, 2021 Dec. 1, 2021 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
375 -0.6%
42.40
15,900 USD
375 -0.6% 42.40 15,900 USD
Nov. 18, 2021 Nov. 18, 2021 B Purchase

Morningside Venture Investments Ltd

Major owner
250,000 +2.0%
40.00
10,000,000 USD
250,000 +2.0% 40.00 10,000,000 USD
Nov. 17, 2021 Nov. 15, 2021 PS Planned sale

Machiels Alec

Non-Executive Director
3,000 -0.4%
43.50
130,500 USD
3,000 -0.4% 43.50 130,500 USD
Nov. 17, 2021 Nov. 15, 2021 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
625 -1.0%
43.50
27,188 USD
625 -1.0% 43.50 27,188 USD
Nov. 17, 2021 Nov. 4, 2021 PS Planned sale

Machiels Alec

Non-Executive Director
3,000 -0.4%
35.00
105,000 USD
3,000 -0.4% 35.00 105,000 USD
Nov. 2, 2021 Nov. 1, 2021 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
625 -1.0%
30.70
19,188 USD
625 -1.0% 30.70 19,188 USD
Oct. 15, 2021 Oct. 14, 2021 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
750 -1.1%
34.57
25,928 USD
750 -1.1% 34.57 25,928 USD
Oct. 5, 2021 Oct. 1, 2021 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
750 -1.1%
33.26
24,945 USD
750 -1.1% 33.26 24,945 USD
July 22, 2021 July 21, 2021 PS Planned sale

DeLong Mark Jeffrey

Senior Vice President

Officer
1,000 -9.5%
65.00
65,000 USD
1,000 -9.5% 65.00 65,000 USD
June 25, 2021 June 24, 2021 PS Planned sale

Deschatelets Pascal

Chief Scientific Officer

Officer
6,250 -0.7%
65.61
410,063 USD
6,250 -0.7% 65.61 410,063 USD
June 16, 2021 June 15, 2021 S Sale

DeLong Mark Jeffrey

Senior Vice President

Officer
4,000 -29.7%
64.96
259,830 USD
4,000 -29.7% 64.96 259,830 USD
June 15, 2021 June 14, 2021 PS Planned sale

Grossi Federico

CHIEF MEDICAL OFFICER

Officer
500 -0.9%
61.84
30,920 USD
500 -0.9% 61.84 30,920 USD
June 15, 2021 June 11, 2021 S Sale

Perry Nicole D

Vice President - Accounting

Officer
1,000 -17.1%
61.56
61,555 USD
1,000 -17.1% 61.56 61,555 USD
June 11, 2021 June 10, 2021 PS Planned sale

SCHEIBLER LUKAS

CHIEF INNOVATION OFFICER

Officer
3,417 -11.4%
60.00
205,020 USD
3,417 -11.4% 60.00 205,020 USD
June 2, 2021 June 1, 2021 PS Planned sale

Perry Nicole D

Vice President - Accounting

Officer
1,000 -17.1%
56.40
56,400 USD
1,000 -17.1% 56.40 56,400 USD
May 25, 2021 May 24, 2021 PS Planned sale

Deschatelets Pascal

Chief Scientific Officer

Officer
6,250 -0.7%
47.40
296,250 USD
6,250 -0.7% 47.40 296,250 USD
May 20, 2021 May 20, 2021 S Sale

Dunlop A. Sinclair

Non-Executive Director
5,773 -15.3%
48.10
277,681 USD
5,773 -15.3% 48.10 277,681 USD
May 20, 2021 May 19, 2021 S Sale

Dunlop A. Sinclair

Non-Executive Director
7,612 -2.5%
50.00
380,600 USD
7,612 -2.5% 50.00 380,600 USD
May 20, 2021 May 18, 2021 S Sale

Dunlop A. Sinclair

Non-Executive Director
800 -0.3%
54.02
43,216 USD
800 -0.3% 54.02 43,216 USD