2024-05-07 |
2024-05-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
1,000
+inf%
1.73
100,000
USD
|
1,000
+inf%
|
1.73
|
100,000
USD
|
|
2024-05-07 |
2024-05-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
1,000
+inf%
1.73
100,000
USD
|
1,000
+inf%
|
1.73
|
100,000
USD
|
|
2024-05-07 |
2024-05-06 |
B
Purchase
|
Jones William Benton
See Remarks
Officer
|
1,000
+15.0%
1.73
100,000
USD
|
1,000
+15.0%
|
1.73
|
100,000
USD
|
|
2023-05-16 |
2023-05-15 |
B
Purchase
|
Grais Linda
Non-Executive Director
|
10,000
+inf%
2.45
24,500
USD
|
10,000
+inf%
|
2.45
|
24,500
USD
|
|
2022-12-20 |
2022-12-20 |
B
Purchase
|
Jones William Benton
See Remarks
Officer
|
20,000
+17.6%
0.79
15,800
USD
|
20,000
+17.6%
|
0.79
|
15,800
USD
|
|
2022-12-15 |
2022-12-14 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
10,000
+0.7%
0.78
7,812
USD
|
10,000
+0.7%
|
0.78
|
7,812
USD
|
|
2022-12-15 |
2022-12-14 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
4,000
+3.1%
0.84
3,364
USD
|
4,000
+3.1%
|
0.84
|
3,364
USD
|
|
2022-12-15 |
2022-12-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
50,000
+3.5%
0.74
37,015
USD
|
50,000
+3.5%
|
0.74
|
37,015
USD
|
|
2022-12-15 |
2022-12-13 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
30,000
+30.2%
0.74
22,275
USD
|
30,000
+30.2%
|
0.74
|
22,275
USD
|
|
2022-09-28 |
2022-09-28 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
25,000
+1.8%
0.76
19,070
USD
|
25,000
+1.8%
|
0.76
|
19,070
USD
|
|
2022-09-20 |
2022-09-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
0.82
4,075
USD
|
5,000
+0.4%
|
0.82
|
4,075
USD
|
|
2022-09-20 |
2022-09-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
2,700
+0.2%
0.82
2,214
USD
|
2,700
+0.2%
|
0.82
|
2,214
USD
|
|
2022-09-20 |
2022-09-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
12,300
+0.9%
0.81
9,964
USD
|
12,300
+0.9%
|
0.81
|
9,964
USD
|
|
2022-06-28 |
2022-06-27 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
1.00
4,985
USD
|
5,000
+0.4%
|
1.00
|
4,985
USD
|
|
2022-06-28 |
2022-06-24 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
1.03
5,150
USD
|
5,000
+0.4%
|
1.03
|
5,150
USD
|
|
2022-06-06 |
2022-06-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
890
+0.1%
1.01
899
USD
|
890
+0.1%
|
1.01
|
899
USD
|
|
2022-06-06 |
2022-06-02 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
170
+0.0%
0.97
165
USD
|
170
+0.0%
|
0.97
|
165
USD
|
|
2022-06-06 |
2022-06-02 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
4,830
+0.4%
0.98
4,733
USD
|
4,830
+0.4%
|
0.98
|
4,733
USD
|
|
2022-04-01 |
2022-03-31 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
15,000
+1.1%
1.64
24,534
USD
|
15,000
+1.1%
|
1.64
|
24,534
USD
|
|
2022-03-17 |
2022-03-17 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
13,878
+16.3%
1.65
22,899
USD
|
13,878
+16.3%
|
1.65
|
22,899
USD
|
|
2022-03-17 |
2022-03-17 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
1.59
7,950
USD
|
5,000
+0.4%
|
1.59
|
7,950
USD
|
|
2022-03-17 |
2022-03-16 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
35,160
+70.0%
1.54
54,146
USD
|
35,160
+70.0%
|
1.54
|
54,146
USD
|
|
2022-03-17 |
2022-03-15 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
25,000
+1.9%
1.47
36,650
USD
|
25,000
+1.9%
|
1.47
|
36,650
USD
|
|
2021-10-01 |
2021-10-01 |
S
Sale
|
EcoR1 Capital, LLC
Large shareholder
|
2,000,000
-96.1%
4.96
9,928,800
USD
|
2,000,000
-96.1%
|
4.96
|
9,928,800
USD
|
|
2021-10-01 |
2021-09-30 |
S
Sale
|
EcoR1 Capital, LLC
Large shareholder
|
3,000,000
-59.0%
5.04
15,131,100
USD
|
3,000,000
-59.0%
|
5.04
|
15,131,100
USD
|
|
2021-02-19 |
2021-02-17 |
B
Purchase
|
ORBIMED ADVISORS LLC
Non-Executive Director
Large shareholder
|
1,285,714
+19.0%
3.50
4,499,999
USD
|
1,285,714
+19.0%
|
3.50
|
4,499,999
USD
|
|
2021-02-19 |
2021-02-17 |
B
Purchase
|
Thompson Peter A.
Non-Executive Director
Large shareholder
|
1,285,714
+19.0%
3.50
4,499,999
USD
|
1,285,714
+19.0%
|
3.50
|
4,499,999
USD
|
|
2021-02-17 |
2021-02-17 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
100,000
+8.5%
3.50
350,000
USD
|
100,000
+8.5%
|
3.50
|
350,000
USD
|
|
2020-07-09 |
2020-07-08 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
741,440
-34.8%
5.37
3,985,166
USD
|
741,440
-34.8%
|
5.37
|
3,985,166
USD
|
|
2020-07-09 |
2020-07-07 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
796,622
-27.2%
5.25
4,183,381
USD
|
796,622
-27.2%
|
5.25
|
4,183,381
USD
|
|
2019-11-14 |
2019-11-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
14,736
+1.3%
3.00
44,240
USD
|
14,736
+1.3%
|
3.00
|
44,240
USD
|
|
2019-11-14 |
2019-11-12 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
272
+0.0%
2.90
789
USD
|
272
+0.0%
|
2.90
|
789
USD
|
|
2019-08-08 |
2019-08-07 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
2,500
+0.2%
3.54
8,850
USD
|
2,500
+0.2%
|
3.54
|
8,850
USD
|
|
2019-08-08 |
2019-08-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
3.58
17,875
USD
|
5,000
+0.4%
|
3.58
|
17,875
USD
|
|
2019-08-08 |
2019-08-06 |
B
Purchase
|
ORBIMED ADVISORS LLC
Non-Executive Director
Large shareholder
|
142,656
+2.2%
3.51
500,723
USD
|
142,656
+2.2%
|
3.51
|
500,723
USD
|
|
2019-08-08 |
2019-08-06 |
B
Purchase
|
Thompson Peter A.
Non-Executive Director
Large shareholder
|
142,656
+2.2%
3.51
500,723
USD
|
142,656
+2.2%
|
3.51
|
500,723
USD
|
|
2019-07-25 |
2019-07-25 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
1,400,000
-32.4%
4.00
5,600,000
USD
|
1,400,000
-32.4%
|
4.00
|
5,600,000
USD
|
|
2019-07-25 |
2019-07-24 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
53,240
-1.2%
5.01
266,711
USD
|
53,240
-1.2%
|
5.01
|
266,711
USD
|
|
2019-07-25 |
2019-07-23 |
S
Sale
|
Novo Holdings A/S
Large shareholder
|
39,716
-0.9%
5.32
211,134
USD
|
39,716
-0.9%
|
5.32
|
211,134
USD
|
|
2019-07-01 |
2019-07-01 |
B
Purchase
|
Thompson Peter A.
Large shareholder
|
59,243
+0.9%
3.91
231,640
USD
|
59,243
+0.9%
|
3.91
|
231,640
USD
|
|
2019-07-01 |
2019-07-01 |
B
Purchase
|
ORBIMED ADVISORS LLC
Large shareholder
|
59,243
+0.9%
3.91
231,640
USD
|
59,243
+0.9%
|
3.91
|
231,640
USD
|
|
2019-07-01 |
2019-06-28 |
B
Purchase
|
Thompson Peter A.
Large shareholder
|
565,178
+9.4%
3.72
2,102,462
USD
|
565,178
+9.4%
|
3.72
|
2,102,462
USD
|
|
2019-07-01 |
2019-06-28 |
B
Purchase
|
ORBIMED ADVISORS LLC
Large shareholder
|
565,178
+9.4%
3.72
2,102,462
USD
|
565,178
+9.4%
|
3.72
|
2,102,462
USD
|
|
2019-07-01 |
2019-06-27 |
B
Purchase
|
Thompson Peter A.
Large shareholder
|
32,923
+0.6%
3.34
109,963
USD
|
32,923
+0.6%
|
3.34
|
109,963
USD
|
|
2019-07-01 |
2019-06-27 |
B
Purchase
|
ORBIMED ADVISORS LLC
Large shareholder
|
32,923
+0.6%
3.34
109,963
USD
|
32,923
+0.6%
|
3.34
|
109,963
USD
|
|
2019-06-17 |
2019-06-14 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
11,657
+1.0%
3.40
39,666
USD
|
11,657
+1.0%
|
3.40
|
39,666
USD
|
|
2019-06-17 |
2019-06-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
343
+0.0%
3.52
1,207
USD
|
343
+0.0%
|
3.52
|
1,207
USD
|
|
2019-06-11 |
2019-06-11 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
6,000
+0.5%
3.67
22,020
USD
|
6,000
+0.5%
|
3.67
|
22,020
USD
|
|
2019-06-11 |
2019-06-07 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
9,212
+0.8%
3.37
31,019
USD
|
9,212
+0.8%
|
3.37
|
31,019
USD
|
|
2019-06-10 |
2019-06-07 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
|
10,000
+24.9%
3.38
33,800
USD
|
10,000
+24.9%
|
3.38
|
33,800
USD
|
|
2019-06-10 |
2019-06-06 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
|
15,500
+62.8%
3.56
55,180
USD
|
15,500
+62.8%
|
3.56
|
55,180
USD
|
|
2018-12-31 |
2018-12-27 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
20,000
+1.8%
3.29
65,884
USD
|
20,000
+1.8%
|
3.29
|
65,884
USD
|
|
2018-12-27 |
2018-12-21 |
B
Purchase
|
LEA LEIV
Chief Financial Officer
Officer
|
24,700
+inf%
4.15
102,409
USD
|
24,700
+inf%
|
4.15
|
102,409
USD
|
|
2018-12-26 |
2018-12-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.5%
4.39
21,950
USD
|
5,000
+0.5%
|
4.39
|
21,950
USD
|
|
2018-12-26 |
2018-12-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.5%
4.40
22,000
USD
|
5,000
+0.5%
|
4.40
|
22,000
USD
|
|
2018-12-10 |
2018-12-06 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
5,000
+0.4%
5.99
29,934
USD
|
5,000
+0.4%
|
5.99
|
29,934
USD
|
|
2018-12-06 |
2018-12-04 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
1,502
+0.1%
5.95
8,937
USD
|
1,502
+0.1%
|
5.95
|
8,937
USD
|
|
2018-03-14 |
2018-03-12 |
B
Purchase
|
Thompson Peter A.
Large shareholder
|
588,235
+10.9%
8.50
4,999,998
USD
|
588,235
+10.9%
|
8.50
|
4,999,998
USD
|
|
2018-03-14 |
2018-03-12 |
B
Purchase
|
ORBIMED ADVISORS LLC
Large shareholder
|
588,235
+10.9%
8.50
4,999,998
USD
|
588,235
+10.9%
|
8.50
|
4,999,998
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Novo Holdings A/S
Large shareholder
|
1,176,470
+36.3%
8.50
9,999,995
USD
|
1,176,470
+36.3%
|
8.50
|
9,999,995
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
126,806
+inf%
8.50
1,077,851
USD
|
126,806
+inf%
|
8.50
|
1,077,851
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
87,668
+inf%
8.50
745,178
USD
|
87,668
+inf%
|
8.50
|
745,178
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
67,769
+inf%
8.50
576,037
USD
|
67,769
+inf%
|
8.50
|
576,037
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
236,128
+inf%
8.50
2,007,088
USD
|
236,128
+inf%
|
8.50
|
2,007,088
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
ADAMS STREET PARTNERS LLC
Large shareholder
|
69,864
+inf%
8.50
593,844
USD
|
69,864
+inf%
|
8.50
|
593,844
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
126,806
+inf%
8.50
1,077,851
USD
|
126,806
+inf%
|
8.50
|
1,077,851
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
87,668
+inf%
8.50
745,178
USD
|
87,668
+inf%
|
8.50
|
745,178
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
67,769
+inf%
8.50
576,037
USD
|
67,769
+inf%
|
8.50
|
576,037
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
236,128
+inf%
8.50
2,007,088
USD
|
236,128
+inf%
|
8.50
|
2,007,088
USD
|
|
2018-03-13 |
2018-03-12 |
B
Purchase
|
Gould Terry P
Large shareholder
|
69,864
+inf%
8.50
593,844
USD
|
69,864
+inf%
|
8.50
|
593,844
USD
|
|
2018-03-12 |
2018-03-12 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
100,000
+9.9%
8.50
850,000
USD
|
100,000
+9.9%
|
8.50
|
850,000
USD
|
|
2017-11-22 |
2017-11-20 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
10,000
+1.0%
10.79
107,850
USD
|
10,000
+1.0%
|
10.79
|
107,850
USD
|
|
2017-06-27 |
2017-06-23 |
B
Purchase
|
Novo Holdings A/S
Large shareholder
|
20,000
+0.6%
10.95
219,000
USD
|
20,000
+0.6%
|
10.95
|
219,000
USD
|
|
2017-06-13 |
2017-06-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
2,500
+0.3%
10.14
25,350
USD
|
2,500
+0.3%
|
10.14
|
25,350
USD
|
|
2017-06-13 |
2017-06-13 |
B
Purchase
|
MILLER RICHARD A MD
President and CEO
Executive Director
|
2,500
+0.3%
9.75
24,375
USD
|
2,500
+0.3%
|
9.75
|
24,375
USD
|
|