|
2026-06-15 |
2026-06-11 |
B
Compra
|
Consejero no ejecutivo
|
92 839
-1.3%
153,61
2.579.486 US$
|
92 839
-1.3%
|
153,61
|
2.579.486 US$
|
|
|
2026-05-20 |
2026-05-18 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
60 424
-28.7%
125,23
3.264.916 US$
|
60 424
-28.7%
|
125,23
|
3.264.916 US$
|
|
|
2026-05-20 |
2026-05-18 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
26 438
+35.4%
113,65
1.074.143 US$
|
26 438
+35.4%
|
113,65
|
1.074.143 US$
|
|
|
2025-07-01 |
2025-06-27 |
S
Venta
|
Consejero no ejecutivo
Gran accionista
|
1 176 332
-14.1%
4,16
4.891.894 US$
|
1 176 332
-14.1%
|
4,16
|
4.891.894 US$
|
|
|
2025-07-01 |
2025-06-27 |
S
Venta
|
Consejero no ejecutivo
Gran accionista
|
1 176 332
-14.1%
4,16
4.891.894 US$
|
1 176 332
-14.1%
|
4,16
|
4.891.894 US$
|
|
|
2024-05-07 |
2024-05-06 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
577 634
+inf%
1,73
1.000.000 US$
|
577 634
+inf%
|
1,73
|
1.000.000 US$
|
|
|
2024-05-07 |
2024-05-06 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
577 634
+inf%
1,73
1.000.000 US$
|
577 634
+inf%
|
1,73
|
1.000.000 US$
|
|
|
2024-05-07 |
2024-05-06 |
B
Compra
|
See Remarks
Oficial
|
20 000
+15.0%
1,73
34.624 US$
|
20 000
+15.0%
|
1,73
|
34.624 US$
|
|
|
2023-05-16 |
2023-05-15 |
B
Compra
|
Consejero no ejecutivo
|
10 000
+inf%
2,45
24.500 US$
|
10 000
+inf%
|
2,45
|
24.500 US$
|
|
|
2022-12-20 |
2022-12-20 |
B
Compra
|
See Remarks
Oficial
|
20 000
+17.6%
0,79
15.800 US$
|
20 000
+17.6%
|
0,79
|
15.800 US$
|
|
|
2022-12-15 |
2022-12-14 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
10 000
+0.7%
0,78
7.812 US$
|
10 000
+0.7%
|
0,78
|
7.812 US$
|
|
|
2022-12-15 |
2022-12-14 |
B
Compra
|
Chief Financial Officer
Oficial
|
4 000
+3.1%
0,84
3.364 US$
|
4 000
+3.1%
|
0,84
|
3.364 US$
|
|
|
2022-12-15 |
2022-12-13 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
50 000
+3.5%
0,74
37.015 US$
|
50 000
+3.5%
|
0,74
|
37.015 US$
|
|
|
2022-12-15 |
2022-12-13 |
B
Compra
|
Chief Financial Officer
Oficial
|
30 000
+30.2%
0,74
22.275 US$
|
30 000
+30.2%
|
0,74
|
22.275 US$
|
|
|
2022-09-28 |
2022-09-28 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
25 000
+1.8%
0,76
19.070 US$
|
25 000
+1.8%
|
0,76
|
19.070 US$
|
|
|
2022-09-20 |
2022-09-20 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
5 000
+0.4%
0,82
4.075 US$
|
5 000
+0.4%
|
0,82
|
4.075 US$
|
|
|
2022-09-20 |
2022-09-20 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
2 700
+0.2%
0,82
2.214 US$
|
2 700
+0.2%
|
0,82
|
2.214 US$
|
|
|
2022-09-20 |
2022-09-20 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
12 300
+0.9%
0,81
9.964 US$
|
12 300
+0.9%
|
0,81
|
9.964 US$
|
|
|
2022-06-28 |
2022-06-27 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
5 000
+0.4%
1,00
4.984 US$
|
5 000
+0.4%
|
1,00
|
4.984 US$
|
|
|
2022-06-28 |
2022-06-24 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
5 000
+0.4%
1,03
5.150 US$
|
5 000
+0.4%
|
1,03
|
5.150 US$
|
|
|
2022-06-06 |
2022-06-06 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
890
+0.1%
1,01
899 US$
|
890
+0.1%
|
1,01
|
899 US$
|
|
|
2022-06-06 |
2022-06-02 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
170
+0.0%
0,97
165 US$
|
170
+0.0%
|
0,97
|
165 US$
|
|
|
2022-06-06 |
2022-06-02 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
4 830
+0.4%
0,98
4.733 US$
|
4 830
+0.4%
|
0,98
|
4.733 US$
|
|
|
2022-04-01 |
2022-03-31 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
15 000
+1.1%
1,64
24.534 US$
|
15 000
+1.1%
|
1,64
|
24.534 US$
|
|
|
2022-03-17 |
2022-03-17 |
B
Compra
|
Chief Financial Officer
Oficial
|
13 878
+16.3%
1,65
22.899 US$
|
13 878
+16.3%
|
1,65
|
22.899 US$
|
|
|
2022-03-17 |
2022-03-17 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
5 000
+0.4%
1,59
7.950 US$
|
5 000
+0.4%
|
1,59
|
7.950 US$
|
|
|
2022-03-17 |
2022-03-16 |
B
Compra
|
Chief Financial Officer
Oficial
|
35 160
+70.0%
1,54
54.146 US$
|
35 160
+70.0%
|
1,54
|
54.146 US$
|
|
|
2022-03-17 |
2022-03-15 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
25 000
+1.9%
1,47
36.650 US$
|
25 000
+1.9%
|
1,47
|
36.650 US$
|
|
|
2021-10-01 |
2021-10-01 |
S
Venta
|
Gran accionista
|
2 000 000
-96.1%
4,96
9.928.800 US$
|
2 000 000
-96.1%
|
4,96
|
9.928.800 US$
|
|
|
2021-10-01 |
2021-09-30 |
S
Venta
|
Gran accionista
|
3 000 000
-59.0%
5,04
15.131.100 US$
|
3 000 000
-59.0%
|
5,04
|
15.131.100 US$
|
|
|
2021-02-19 |
2021-02-17 |
B
Compra
|
Consejero no ejecutivo
Gran accionista
|
1 285 714
+19.0%
3,50
4.499.999 US$
|
1 285 714
+19.0%
|
3,50
|
4.499.999 US$
|
|
|
2021-02-19 |
2021-02-17 |
B
Compra
|
Consejero no ejecutivo
Gran accionista
|
1 285 714
+19.0%
3,50
4.499.999 US$
|
1 285 714
+19.0%
|
3,50
|
4.499.999 US$
|
|
|
2021-02-17 |
2021-02-17 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
100 000
+8.5%
3,50
350.000 US$
|
100 000
+8.5%
|
3,50
|
350.000 US$
|
|
|
2020-07-09 |
2020-07-08 |
S
Venta
|
Gran accionista
|
741 440
-34.8%
5,37
3.985.166 US$
|
741 440
-34.8%
|
5,37
|
3.985.166 US$
|
|
|
2020-07-09 |
2020-07-07 |
S
Venta
|
Gran accionista
|
796 622
-27.2%
5,25
4.183.381 US$
|
796 622
-27.2%
|
5,25
|
4.183.381 US$
|
|
|
2019-11-14 |
2019-11-13 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
14 736
+1.3%
3,00
44.240 US$
|
14 736
+1.3%
|
3,00
|
44.240 US$
|
|
|
2019-11-14 |
2019-11-12 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
272
+0.0%
2,90
789 US$
|
272
+0.0%
|
2,90
|
789 US$
|
|
|
2019-08-08 |
2019-08-07 |
B
Compra
|
MILLER RICHARD A MD
President and CEO
Consejero ejecutivo
|
2 500
+0.2%
3,54
8.850 US$
|
2 500
+0.2%
|
3,54
|
8.850 US$
|
|
|
2019-08-08 |
2019-08-06 |
B
Compra
|
MILLER RICHARD A MD
President and CEO
Consejero ejecutivo
|
5 000
+0.4%
3,58
17.875 US$
|
5 000
+0.4%
|
3,58
|
17.875 US$
|
|
|
2019-08-08 |
2019-08-06 |
B
Compra
|
ORBIMED ADVISORS LLC
Consejero no ejecutivo
Gran accionista
|
142 656
+2.2%
3,51
500.723 US$
|
142 656
+2.2%
|
3,51
|
500.723 US$
|
|
|
2019-08-08 |
2019-08-06 |
B
Compra
|
Thompson Peter A.
Consejero no ejecutivo
Gran accionista
|
142 656
+2.2%
3,51
500.723 US$
|
142 656
+2.2%
|
3,51
|
500.723 US$
|
|
|
2019-07-25 |
2019-07-25 |
S
Venta
|
Gran accionista
|
1 400 000
-32.4%
4,00
5.600.000 US$
|
1 400 000
-32.4%
|
4,00
|
5.600.000 US$
|
|
|
2019-07-25 |
2019-07-24 |
S
Venta
|
Gran accionista
|
53 240
-1.2%
5,01
266.711 US$
|
53 240
-1.2%
|
5,01
|
266.711 US$
|
|
|
2019-07-25 |
2019-07-23 |
S
Venta
|
Gran accionista
|
39 716
-0.9%
5,32
211.134 US$
|
39 716
-0.9%
|
5,32
|
211.134 US$
|
|
|
2019-07-01 |
2019-07-01 |
B
Compra
|
Gran accionista
|
59 243
+0.9%
3,91
231.640 US$
|
59 243
+0.9%
|
3,91
|
231.640 US$
|
|
|
2019-07-01 |
2019-07-01 |
B
Compra
|
Gran accionista
|
59 243
+0.9%
3,91
231.640 US$
|
59 243
+0.9%
|
3,91
|
231.640 US$
|
|
|
2019-07-01 |
2019-06-28 |
B
Compra
|
Gran accionista
|
565 178
+9.4%
3,72
2.102.462 US$
|
565 178
+9.4%
|
3,72
|
2.102.462 US$
|
|
|
2019-07-01 |
2019-06-28 |
B
Compra
|
Gran accionista
|
565 178
+9.4%
3,72
2.102.462 US$
|
565 178
+9.4%
|
3,72
|
2.102.462 US$
|
|
|
2019-07-01 |
2019-06-27 |
B
Compra
|
Gran accionista
|
32 923
+0.6%
3,34
109.963 US$
|
32 923
+0.6%
|
3,34
|
109.963 US$
|
|
|
2019-07-01 |
2019-06-27 |
B
Compra
|
Gran accionista
|
32 923
+0.6%
3,34
109.963 US$
|
32 923
+0.6%
|
3,34
|
109.963 US$
|
|
|
2019-06-17 |
2019-06-14 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
11 657
+1.0%
3,40
39.666 US$
|
11 657
+1.0%
|
3,40
|
39.666 US$
|
|
|
2019-06-17 |
2019-06-13 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
343
+0.0%
3,52
1.207 US$
|
343
+0.0%
|
3,52
|
1.207 US$
|
|
|
2019-06-11 |
2019-06-11 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
6 000
+0.5%
3,67
22.020 US$
|
6 000
+0.5%
|
3,67
|
22.020 US$
|
|
|
2019-06-11 |
2019-06-07 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
9 212
+0.8%
3,37
31.019 US$
|
9 212
+0.8%
|
3,37
|
31.019 US$
|
|
|
2019-06-10 |
2019-06-07 |
B
Compra
|
Chief Financial Officer
|
10 000
+24.9%
3,38
33.800 US$
|
10 000
+24.9%
|
3,38
|
33.800 US$
|
|
|
2019-06-10 |
2019-06-06 |
B
Compra
|
Chief Financial Officer
|
15 500
+62.8%
3,56
55.180 US$
|
15 500
+62.8%
|
3,56
|
55.180 US$
|
|
|
2018-12-31 |
2018-12-27 |
B
Compra
|
MILLER RICHARD A MD
President and CEO
Consejero ejecutivo
|
20 000
+1.8%
3,29
65.884 US$
|
20 000
+1.8%
|
3,29
|
65.884 US$
|
|
|
2018-12-27 |
2018-12-21 |
B
Compra
|
LEA LEIV
Chief Financial Officer
Oficial
|
24 700
+inf%
4,15
102.409 US$
|
24 700
+inf%
|
4,15
|
102.409 US$
|
|
|
2018-12-26 |
2018-12-20 |
B
Compra
|
MILLER RICHARD A MD
President and CEO
Consejero ejecutivo
|
5 000
+0.5%
4,39
21.950 US$
|
5 000
+0.5%
|
4,39
|
21.950 US$
|
|
|
2018-12-26 |
2018-12-20 |
B
Compra
|
MILLER RICHARD A MD
President and CEO
Consejero ejecutivo
|
5 000
+0.5%
4,40
22.000 US$
|
5 000
+0.5%
|
4,40
|
22.000 US$
|
|
|
2018-12-10 |
2018-12-06 |
B
Compra
|
MILLER RICHARD A MD
President and CEO
Consejero ejecutivo
|
5 000
+0.4%
5,99
29.934 US$
|
5 000
+0.4%
|
5,99
|
29.934 US$
|
|
|
2018-12-06 |
2018-12-04 |
B
Compra
|
MILLER RICHARD A MD
President and CEO
Consejero ejecutivo
|
1 502
+0.1%
5,95
8.937 US$
|
1 502
+0.1%
|
5,95
|
8.937 US$
|
|
|
2018-03-14 |
2018-03-12 |
B
Compra
|
Thompson Peter A.
Gran accionista
|
588 235
+10.9%
8,50
4.999.998 US$
|
588 235
+10.9%
|
8,50
|
4.999.998 US$
|
|
|
2018-03-14 |
2018-03-12 |
B
Compra
|
ORBIMED ADVISORS LLC
Gran accionista
|
588 235
+10.9%
8,50
4.999.998 US$
|
588 235
+10.9%
|
8,50
|
4.999.998 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
Novo Holdings A/S
Gran accionista
|
1 176 470
+36.3%
8,50
9.999.995 US$
|
1 176 470
+36.3%
|
8,50
|
9.999.995 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
ADAMS STREET PARTNERS LLC
Gran accionista
|
126 806
+inf%
8,50
1.077.851 US$
|
126 806
+inf%
|
8,50
|
1.077.851 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
ADAMS STREET PARTNERS LLC
Gran accionista
|
87 668
+inf%
8,50
745.178 US$
|
87 668
+inf%
|
8,50
|
745.178 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
ADAMS STREET PARTNERS LLC
Gran accionista
|
67 769
+inf%
8,50
576.036 US$
|
67 769
+inf%
|
8,50
|
576.036 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
ADAMS STREET PARTNERS LLC
Gran accionista
|
236 128
+inf%
8,50
2.007.088 US$
|
236 128
+inf%
|
8,50
|
2.007.088 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
ADAMS STREET PARTNERS LLC
Gran accionista
|
69 864
+inf%
8,50
593.844 US$
|
69 864
+inf%
|
8,50
|
593.844 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
Gould Terry P
Gran accionista
|
126 806
+inf%
8,50
1.077.851 US$
|
126 806
+inf%
|
8,50
|
1.077.851 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
Gould Terry P
Gran accionista
|
87 668
+inf%
8,50
745.178 US$
|
87 668
+inf%
|
8,50
|
745.178 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
Gould Terry P
Gran accionista
|
67 769
+inf%
8,50
576.036 US$
|
67 769
+inf%
|
8,50
|
576.036 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
Gould Terry P
Gran accionista
|
236 128
+inf%
8,50
2.007.088 US$
|
236 128
+inf%
|
8,50
|
2.007.088 US$
|
|
|
2018-03-13 |
2018-03-12 |
B
Compra
|
Gould Terry P
Gran accionista
|
69 864
+inf%
8,50
593.844 US$
|
69 864
+inf%
|
8,50
|
593.844 US$
|
|