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United States Biotechnology & Medical Research

aTyr Pharma Inc (LIFE)

Track

Over the last 90 days, aTyr Pharma Inc. has seen one insider buy transaction totaling $49,630. This contrasts with earlier periods showing multiple buy transactions from Paul Schimmel, including a significant purchase of $612,436.89 in October 2025. Recent executive selling activity occurred in February 2026.
Stock chart
Ticker: LIFE Exchange: NAS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
SCHIMMEL PAUL
1 purchase — total 49,630 USD
Buy 27 May 2026
Value US$4,096,120.95 | Price 331.31 | Shares 77,855
Sale 4 Feb 2026
Value US$3,033,909.42 | Price 269.35 | Shares 65,774
Sale 4 Feb 2026
Value US$1,248,270.74 | Price 19.04 | Shares 77,529
Sale 4 Feb 2026
Value US$1,520.61 | Price 0.98 | Shares 1,558
Sale 4 Feb 2026
Value US$1,520.61 | Price 0.98 | Shares 1,558
Sale 4 Feb 2026
Value US$1,091.28 | Price 0.98 | Shares 1,118
Sale 4 Feb 2026
Value US$1,091.28 | Price 0.98 | Shares 1,118
Buy 9 Oct 2025
Value US$299,364.26 | Price 0.94 | Shares 317,999
Buy 8 Oct 2025
Value US$612,436.90 | Price 0.90 | Shares 682,001
Buy 17 Mar 2025
Value US$15,000.00 | Price 4.00 | Shares 3,750
Sale 4 Feb 2025
Value US$4,740.12 | Price 3.78 | Shares 1,254
Sale 4 Feb 2025
Value US$3,398.22 | Price 3.78 | Shares 899
Buy 24 Jul 2024
Value US$101,038.37 | Price 1.93 | Shares 52,300
Buy 23 Jul 2024
Value US$12,074.76 | Price 1.82 | Shares 6,648
Buy 22 Jul 2024
Value US$71,500.27 | Price 1.74 | Shares 41,052
Buy 5 Jun 2024
Value US$9,276.00 | Price 1.86 | Shares 5,000
Buy 31 May 2024
Value US$8,950.00 | Price 1.79 | Shares 5,000
Buy 31 May 2024
Value US$36,140.00 | Price 1.81 | Shares 20,000
Buy 30 May 2024
Value US$87,500.00 | Price 1.75 | Shares 50,000
Sale 6 Feb 2024
Value US$2,687.10 | Price 1.69 | Shares 1,590
Buy 12 Dec 2023
Value US$14,136.00 | Price 1.18 | Shares 12,000
Buy 11 Dec 2023
Value US$3,510.00 | Price 1.17 | Shares 3,000
Buy 13 Nov 2023
Value US$15,085.16 | Price 1.11 | Shares 13,578
Buy 10 Nov 2023
Value US$1,618.24 | Price 1.14 | Shares 1,422
Buy 28 Jul 2023
Value US$30,223.50 | Price 2.01 | Shares 15,000
Buy 10 May 2023
Value US$450,000.00 | Price 2.25 | Shares 200,000
Sale 6 Feb 2023
Value US$3,695.76 | Price 2.36 | Shares 1,566
Buy 21 Nov 2022
Value US$21,405.00 | Price 2.14 | Shares 10,000
Buy 1 Jul 2022
Value US$43,164.00 | Price 2.88 | Shares 15,000
Planned buy 13 Jan 2022
Value US$12,980.25 | Price 6.75 | Shares 1,923
Buy 7 Jan 2022
Value US$33,806.50 | Price 6.76 | Shares 5,000
Buy 15 Nov 2021
Value US$21,437.50 | Price 8.58 | Shares 2,500
Sale 21 May 2021
Value US$10,850.00 | Price 4.34 | Shares 2,500
Buy 18 May 2021
Value US$199,000.00 | Price 3.98 | Shares 50,000
Buy 18 May 2021
Value US$40,100.00 | Price 4.01 | Shares 10,000
Sale 9 Feb 2021
Value US$5,959.48 | Price 7.66 | Shares 778
Sale 9 Feb 2021
Value US$2,987.40 | Price 7.66 | Shares 390
Sale 2 Sep 2020
Value US$29,112.60 | Price 4.01 | Shares 7,260
Sale 28 Aug 2020
Value US$400.00 | Price 4.00 | Shares 100
Sale 27 Aug 2020
Value US$22,249.60 | Price 4.09 | Shares 5,440
Sale 26 Aug 2020
Value US$9,451.20 | Price 4.30 | Shares 2,200
Buy 19 Jun 2020
Value US$7,807.00 | Price 4.22 | Shares 1,850
Buy 19 Jun 2020
Value US$25,620.00 | Price 4.27 | Shares 6,000
Planned sale 20 May 2020
Value US$1,165.64 | Price 3.62 | Shares 322
Sale 20 May 2020
Value US$30,738.63 | Price 3.64 | Shares 8,447
Buy 10 Feb 2020
Value US$1,079,500.00 | Price 4.25 | Shares 254,000
Sale 7 Feb 2020
Value US$1,511.25 | Price 4.03 | Shares 375
Sale 7 Feb 2020
Value US$3,002.35 | Price 4.03 | Shares 745
Planned sale 17 May 2019
Value US$2,093.42 | Price 0.45 | Shares 4,651
Buy 21 Dec 2018
Value US$82,602.00 | Price 0.42 | Shares 195,000
Buy 20 Dec 2018
Value US$20,645.00 | Price 0.41 | Shares 50,000
Buy 26 Nov 2018
Value US$79,795.95 | Price 0.54 | Shares 147,225
Buy 20 Sep 2018
Value US$31,737.60 | Price 0.84 | Shares 38,000
Buy 19 Sep 2018
Value US$21,117.20 | Price 0.81 | Shares 26,000
Buy 14 Sep 2018
Value US$19,055.40 | Price 0.73 | Shares 26,000
Buy 4 Sep 2018
Value US$15,709.07 | Price 0.76 | Shares 20,749
Buy 31 Aug 2018
Value US$15,752.00 | Price 0.72 | Shares 22,000
Buy 30 Aug 2018
Value US$67,482.97 | Price 0.76 | Shares 89,275
Buy 29 Aug 2018
Value US$54,090.41 | Price 0.72 | Shares 75,136
Buy 18 May 2018
Value US$149,445.00 | Price 1.00 | Shares 150,000
Sale 16 May 2018
Value US$2,216,923.66 | Price 0.81 | Shares 2,733,231
Sale 15 May 2018
Value US$173,062.28 | Price 1.43 | Shares 121,294
Sale 14 May 2018
Value US$609,069.71 | Price 1.72 | Shares 354,791
Planned sale 8 Feb 2018
Value US$4,766.80 | Price 3.40 | Shares 1,402
Planned sale 8 Feb 2018
Value US$4,766.80 | Price 3.40 | Shares 1,402
Sale 13 Nov 2017
Value US$4,277.85 | Price 3.95 | Shares 1,083
Sale 10 Nov 2017
Value US$23,444.69 | Price 4.00 | Shares 5,860
Sale 9 Nov 2017
Value US$24,151.18 | Price 4.15 | Shares 5,819
Sale 8 Nov 2017
Value US$4,601.00 | Price 4.30 | Shares 1,070
Buy 1 Nov 2017
Value US$118,694.40 | Price 4.80 | Shares 24,728
Buy 1 Oct 2017
Value US$24,638.95 | Price 5.05 | Shares 4,879
Planned buy 31 Aug 2017
Value US$100,000.40 | Price 2.65 | Shares 37,736
Buy 31 Aug 2017
Value US$249,990.40 | Price 2.65 | Shares 94,336
Planned buy 24 Apr 2017
Value US$372.00 | Price 3.00 | Shares 124
Planned buy 20 Apr 2017
Value US$4,656.00 | Price 3.00 | Shares 1,552
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-05-28 2026-05-27 B Purchase
1.6
SCHIMMEL PAUL
Non-Executive Director
77,855 -7.7%
331.31
US$4,096,121 		77,855 -7.7% 331.31 US$4,096,121
2026-02-04 2026-02-04 S Sale
3.1
Shukla Sanjay

President and CEO

Executive Director
65,774 +24.2%
269.35
US$3,033,909 		65,774 +24.2% 269.35 US$3,033,909
2026-02-04 2026-02-04 S Sale
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
73,747 -2.5%
99.04
US$25,993 		73,747 -2.5% 99.04 US$25,993
2026-02-04 2026-02-04 S Sale
DENYES NANCY

General Counsel

Officer
1,118 -3.3%
0.98
US$1,091 		1,118 -3.3% 0.98 US$1,091
2026-02-04 2026-02-04 S Sale
3.1
Shukla Sanjay

President and CEO

Executive Director
3,745 -2.4%
0.98
US$3,655 		3,745 -2.4% 0.98 US$3,655
2026-02-04 2026-02-04 S Sale
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
1,558 -4.0%
0.98
US$1,521 		1,558 -4.0% 0.98 US$1,521
2026-02-04 2026-02-04 S Sale
DENYES NANCY

General Counsel

Officer
1,118 -3.3%
0.98
US$1,091 		1,118 -3.3% 0.98 US$1,091
2025-10-09 2025-10-09 B Purchase
1.6
SCHIMMEL PAUL
Non-Executive Director
317,999 +29.0%
0.94
US$299,364 		317,999 +29.0% 0.94 US$299,364
2025-10-09 2025-10-08 B Purchase
1.6
SCHIMMEL PAUL
Non-Executive Director
682,001 +165.1%
0.90
US$612,437 		682,001 +165.1% 0.90 US$612,437
2025-03-17 2025-03-17 B Purchase
Gross Jane A
Non-Executive Director
3,750 +62.5%
4.00
US$15,000 		3,750 +62.5% 4.00 US$15,000
2025-02-04 2025-02-04 S Sale
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
1,254 -3.8%
3.78
US$4,740 		1,254 -3.8% 3.78 US$4,740
2025-02-04 2025-02-04 S Sale
DENYES NANCY

General Counsel

Officer
899 -3.3%
3.78
US$3,398 		899 -3.3% 3.78 US$3,398
2024-07-24 2024-07-24 B Purchase
1.6
SCHIMMEL PAUL
Non-Executive Director
52,300 +14.5%
1.93
US$101,038 		52,300 +14.5% 1.93 US$101,038
2024-07-24 2024-07-23 B Purchase
1.6
SCHIMMEL PAUL
Non-Executive Director
6,648 +1.9%
1.82
US$12,075 		6,648 +1.9% 1.82 US$12,075
2024-07-24 2024-07-22 B Purchase
1.6
SCHIMMEL PAUL
Non-Executive Director
41,052 +13.1%
1.74
US$71,500 		41,052 +13.1% 1.74 US$71,500
2024-06-06 2024-06-05 B Purchase
DENYES NANCY

General Counsel

Officer
5,000 +29.0%
1.86
US$9,276 		5,000 +29.0% 1.86 US$9,276
2024-06-03 2024-05-31 B Purchase
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
5,000 +21.8%
1.79
US$8,950 		5,000 +21.8% 1.79 US$8,950
2024-06-03 2024-05-31 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
20,000 +17.2%
1.81
US$36,140 		20,000 +17.2% 1.81 US$36,140
2024-06-03 2024-05-30 B Purchase
1.2
COUGHLIN TIMOTHY
Non-Executive Director
50,000 +833.3%
1.75
US$87,500 		50,000 +833.3% 1.75 US$87,500
2024-02-06 2024-02-06 S Sale
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
1,590 -7.1%
1.69
US$2,687 		1,590 -7.1% 1.69 US$2,687
2023-12-12 2023-12-12 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
12,000 +12.7%
1.18
US$14,136 		12,000 +12.7% 1.18 US$14,136
2023-12-12 2023-12-11 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
3,000 +3.3%
1.17
US$3,510 		3,000 +3.3% 1.17 US$3,510
2023-11-13 2023-11-13 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
13,578 +17.5%
1.11
US$15,085 		13,578 +17.5% 1.11 US$15,085
2023-11-13 2023-11-10 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
1,422 +1.9%
1.14
US$1,618 		1,422 +1.9% 1.14 US$1,618
2023-08-01 2023-07-28 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
15,000 +24.5%
2.01
US$30,224 		15,000 +24.5% 2.01 US$30,224
2023-05-11 2023-05-10 B Purchase
1.6
SCHIMMEL PAUL
Non-Executive Director
200,000 +177.0%
2.25
US$450,000 		200,000 +177.0% 2.25 US$450,000
2023-02-06 2023-02-06 S Sale
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
1,566 -9.2%
2.36
US$3,696 		1,566 -9.2% 2.36 US$3,696
2022-11-21 2022-11-21 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
10,000 +24.5%
2.14
US$21,405 		10,000 +24.5% 2.14 US$21,405
2022-07-06 2022-07-01 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
15,000 +58.1%
2.88
US$43,164 		15,000 +58.1% 2.88 US$43,164
2022-01-18 2022-01-13 PP Planned purchase
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
1,923 +18.9%
6.75
US$12,980 		1,923 +18.9% 6.75 US$12,980
2022-01-10 2022-01-07 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
5,000 +24.0%
6.76
US$33,806 		5,000 +24.0% 6.76 US$33,806
2021-11-15 2021-11-15 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
2,500 +13.7%
8.58
US$21,438 		2,500 +13.7% 8.58 US$21,438
2021-05-25 2021-05-21 S Sale
2.9
CLARKE JOHN K
Non-Executive Director
2,500 -2.3%
4.34
US$10,850 		2,500 -2.3% 4.34 US$10,850
2021-05-20 2021-05-18 B Purchase
1.6
SCHIMMEL PAUL
Non-Executive Director
50,000 +79.3%
3.98
US$199,000 		50,000 +79.3% 3.98 US$199,000
2021-05-20 2021-05-18 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
10,000 +120.5%
4.01
US$40,100 		10,000 +120.5% 4.01 US$40,100
2021-02-09 2021-02-09 S Sale
3.1
Shukla Sanjay

President and CEO

Executive Director
778 -8.6%
7.66
US$5,959 		778 -8.6% 7.66 US$5,959
2021-02-09 2021-02-09 S Sale
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
390 -3.8%
7.66
US$2,987 		390 -3.8% 7.66 US$2,987
2020-09-03 2020-09-02 S Sale
2.9
CLARKE JOHN K
Non-Executive Director
7,260 -6.2%
4.01
US$29,113 		7,260 -6.2% 4.01 US$29,113
2020-09-03 2020-08-28 S Sale
2.9
CLARKE JOHN K
Non-Executive Director
100 -0.1%
4.00
US$400 		100 -0.1% 4.00 US$400
2020-08-28 2020-08-27 S Sale
2.9
CLARKE JOHN K
Non-Executive Director
5,440 -4.4%
4.09
US$22,250 		5,440 -4.4% 4.09 US$22,250
2020-08-28 2020-08-26 S Sale
2.9
CLARKE JOHN K
Non-Executive Director
2,200 -1.8%
4.30
US$9,451 		2,200 -1.8% 4.30 US$9,451
2020-06-23 2020-06-19 B Purchase
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
1,850 +25.3%
4.22
US$7,807 		1,850 +25.3% 4.22 US$7,807
2020-06-23 2020-06-19 B Purchase
3.1
Shukla Sanjay

President and CEO

Executive Director
6,000 +464.8%
4.27
US$25,620 		6,000 +464.8% 4.27 US$25,620
2020-05-28 2020-05-20 PlS Planned sale
DENYES NANCY

General Counsel

Officer
322 -10.5%
3.62
US$1,166 		322 -10.5% 3.62 US$1,166
2020-05-22 2020-05-20 S Sale
1.6
SCHIMMEL PAUL
Non-Executive Director
8,447 -1.9%
3.64
US$30,739 		8,447 -1.9% 3.64 US$30,739
2020-02-11 2020-02-10 B Purchase
1.6
SCHIMMEL PAUL
Non-Executive Director
254,000 +138.4%
4.25
US$1,079,500 		254,000 +138.4% 4.25 US$1,079,500
2020-02-07 2020-02-07 S Sale
2.7
Broadfoot Jill Marie

Chief Financial Officer

Officer
375 -5.0%
4.03
US$1,511 		375 -5.0% 4.03 US$1,511
2020-02-07 2020-02-07 S Sale
3.1
Shukla Sanjay

President and CEO

Officer
745 -36.6%
4.03
US$3,002 		745 -36.6% 4.03 US$3,002
2019-05-20 2019-05-17 PlS Planned sale
Krueger Nancy

General Counsel

Officer
4,651 -15.5%
0.45
US$2,093 		4,651 -15.5% 0.45 US$2,093
2018-12-26 2018-12-21 B Purchase MENDLEIN JOHN Non-Executive Director
195,000 +46.4%
0.42
US$82,602 		195,000 +46.4% 0.42 US$82,602
2018-12-26 2018-12-20 B Purchase MENDLEIN JOHN Non-Executive Director
50,000 +13.5%
0.41
US$20,645 		50,000 +13.5% 0.41 US$20,645
2018-11-28 2018-11-26 B Purchase SCHIMMEL PAUL Non-Executive Director
147,225 +20.0%
0.54
US$79,796 		147,225 +20.0% 0.54 US$79,796
2018-09-21 2018-09-20 B Purchase Broadfoot Jill Marie

Chief Financial Officer

Officer
38,000 +73.1%
0.84
US$31,738 		38,000 +73.1% 0.84 US$31,738
2018-09-21 2018-09-19 B Purchase Broadfoot Jill Marie

Chief Financial Officer

Officer
26,000 +100.0%
0.81
US$21,117 		26,000 +100.0% 0.81 US$21,117
2018-09-18 2018-09-14 B Purchase Broadfoot Jill Marie

Chief Financial Officer

Officer
26,000 +inf%
0.73
US$19,055 		26,000 +inf% 0.73 US$19,055
2018-09-05 2018-09-04 B Purchase SCHIMMEL PAUL Non-Executive Director
20,749 +2.9%
0.76
US$15,709 		20,749 +2.9% 0.76 US$15,709
2018-09-05 2018-08-31 B Purchase SCHIMMEL PAUL Non-Executive Director
22,000 +3.2%
0.72
US$15,752 		22,000 +3.2% 0.72 US$15,752
2018-08-31 2018-08-30 B Purchase SCHIMMEL PAUL Non-Executive Director
89,275 +14.8%
0.76
US$67,483 		89,275 +14.8% 0.76 US$67,483
2018-08-31 2018-08-29 B Purchase SCHIMMEL PAUL Non-Executive Director
75,136 +14.2%
0.72
US$54,090 		75,136 +14.2% 0.72 US$54,090
2018-05-21 2018-05-18 B Purchase SCHIMMEL PAUL Non-Executive Director
150,000 +39.7%
1.00
US$149,445 		150,000 +39.7% 1.00 US$149,445
2018-05-16 2018-05-16 S Sale EcoR1 Capital Fund Qualified, L.P. Large shareholder
2,733,231 -100.0%
0.81
US$2,216,924 		2,733,231 -100.0% 0.81 US$2,216,924
2018-05-16 2018-05-15 S Sale EcoR1 Capital Fund Qualified, L.P. Large shareholder
121,294 -4.2%
1.43
US$173,062 		121,294 -4.2% 1.43 US$173,062
2018-05-16 2018-05-14 S Sale EcoR1 Capital Fund Qualified, L.P. Large shareholder
354,791 -11.1%
1.72
US$609,070 		354,791 -11.1% 1.72 US$609,070
2018-02-08 2018-02-08 PlS Planned sale Blake John T

Senior Vice President, Finance

Officer
1,402 -42.1%
3.40
US$4,767 		1,402 -42.1% 3.40 US$4,767
2018-02-08 2018-02-08 PlS Planned sale
Amanullah Ashraf

See Remarks

Officer
1,402 -42.1%
3.40
US$4,767 		1,402 -42.1% 3.40 US$4,767
2017-12-14 2017-11-13 S Sale EcoR1 Capital Fund Qualified, L.P. Large shareholder
1,083 -0.0%
3.95
US$4,278 		1,083 -0.0% 3.95 US$4,278
2017-12-14 2017-11-10 S Sale EcoR1 Capital Fund Qualified, L.P. Large shareholder
5,860 -0.2%
4.00
US$23,445 		5,860 -0.2% 4.00 US$23,445
2017-12-14 2017-11-09 S Sale EcoR1 Capital Fund Qualified, L.P. Large shareholder
5,819 -0.2%
4.15
US$24,151 		5,819 -0.2% 4.15 US$24,151
2017-12-14 2017-11-08 S Sale EcoR1 Capital Fund Qualified, L.P. Large shareholder
1,070 -0.0%
4.30
US$4,601 		1,070 -0.0% 4.30 US$4,601
2017-12-14 2017-11-01 B Purchase EcoR1 Capital Fund Qualified, L.P. Large shareholder
24,728 +0.8%
4.80
US$118,694 		24,728 +0.8% 4.80 US$118,694
2017-12-14 2017-10-01 B Purchase EcoR1 Capital Fund Qualified, L.P. Large shareholder
4,879 +0.2%
5.05
US$24,639 		4,879 +0.2% 5.05 US$24,639
2017-09-05 2017-08-31 PP Planned purchase MENDLEIN JOHN

CEO and Director

Executive Director
37,736 +11.4%
2.65
US$100,000 		37,736 +11.4% 2.65 US$100,000
2017-09-05 2017-08-31 B Purchase SCHIMMEL PAUL
94,336 +33.3%
2.65
US$249,990 		94,336 +33.3% 2.65 US$249,990
2017-04-26 2017-04-24 PP Planned purchase MENDLEIN JOHN

CEO and Director

Executive Director
124 +0.0%
3.00
US$372 		124 +0.0% 3.00 US$372
2017-04-20 2017-04-20 PP Planned purchase MENDLEIN JOHN

CEO and Director

Executive Director
1,552 +0.5%
3.00
US$4,656 		1,552 +0.5% 3.00 US$4,656
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