|
2026-05-28 |
2026-05-27 |
B
Compra
|
Consejero no ejecutivo
|
77 855
-7.7%
331,31
4.096.121 US$
|
77 855
-7.7%
|
331,31
|
4.096.121 US$
|
|
|
2026-02-04 |
2026-02-04 |
S
Venta
|
President and CEO
Consejero ejecutivo
|
65 774
+24.2%
269,35
3.033.909 US$
|
65 774
+24.2%
|
269,35
|
3.033.909 US$
|
|
|
2026-02-04 |
2026-02-04 |
S
Venta
|
Chief Financial Officer
Oficial
|
73 747
-2.5%
99,04
25.993 US$
|
73 747
-2.5%
|
99,04
|
25.993 US$
|
|
|
2026-02-04 |
2026-02-04 |
S
Venta
|
General Counsel
Oficial
|
1 118
-3.3%
0,98
1.091 US$
|
1 118
-3.3%
|
0,98
|
1.091 US$
|
|
|
2026-02-04 |
2026-02-04 |
S
Venta
|
President and CEO
Consejero ejecutivo
|
3 745
-2.4%
0,98
3.655 US$
|
3 745
-2.4%
|
0,98
|
3.655 US$
|
|
|
2026-02-04 |
2026-02-04 |
S
Venta
|
Chief Financial Officer
Oficial
|
1 558
-4.0%
0,98
1.521 US$
|
1 558
-4.0%
|
0,98
|
1.521 US$
|
|
|
2026-02-04 |
2026-02-04 |
S
Venta
|
General Counsel
Oficial
|
1 118
-3.3%
0,98
1.091 US$
|
1 118
-3.3%
|
0,98
|
1.091 US$
|
|
|
2025-10-09 |
2025-10-09 |
B
Compra
|
Consejero no ejecutivo
|
317 999
+29.0%
0,94
299.364 US$
|
317 999
+29.0%
|
0,94
|
299.364 US$
|
|
|
2025-10-09 |
2025-10-08 |
B
Compra
|
Consejero no ejecutivo
|
682 001
+165.1%
0,90
612.437 US$
|
682 001
+165.1%
|
0,90
|
612.437 US$
|
|
|
2025-03-17 |
2025-03-17 |
B
Compra
|
Consejero no ejecutivo
|
3 750
+62.5%
4,00
15.000 US$
|
3 750
+62.5%
|
4,00
|
15.000 US$
|
|
|
2025-02-04 |
2025-02-04 |
S
Venta
|
Chief Financial Officer
Oficial
|
1 254
-3.8%
3,78
4.740 US$
|
1 254
-3.8%
|
3,78
|
4.740 US$
|
|
|
2025-02-04 |
2025-02-04 |
S
Venta
|
General Counsel
Oficial
|
899
-3.3%
3,78
3.398 US$
|
899
-3.3%
|
3,78
|
3.398 US$
|
|
|
2024-07-24 |
2024-07-24 |
B
Compra
|
Consejero no ejecutivo
|
52 300
+14.5%
1,93
101.038 US$
|
52 300
+14.5%
|
1,93
|
101.038 US$
|
|
|
2024-07-24 |
2024-07-23 |
B
Compra
|
Consejero no ejecutivo
|
6 648
+1.9%
1,82
12.075 US$
|
6 648
+1.9%
|
1,82
|
12.075 US$
|
|
|
2024-07-24 |
2024-07-22 |
B
Compra
|
Consejero no ejecutivo
|
41 052
+13.1%
1,74
71.500 US$
|
41 052
+13.1%
|
1,74
|
71.500 US$
|
|
|
2024-06-06 |
2024-06-05 |
B
Compra
|
General Counsel
Oficial
|
5 000
+29.0%
1,86
9.276 US$
|
5 000
+29.0%
|
1,86
|
9.276 US$
|
|
|
2024-06-03 |
2024-05-31 |
B
Compra
|
Chief Financial Officer
Oficial
|
5 000
+21.8%
1,79
8.950 US$
|
5 000
+21.8%
|
1,79
|
8.950 US$
|
|
|
2024-06-03 |
2024-05-31 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
20 000
+17.2%
1,81
36.140 US$
|
20 000
+17.2%
|
1,81
|
36.140 US$
|
|
|
2024-06-03 |
2024-05-30 |
B
Compra
|
Consejero no ejecutivo
|
50 000
+833.3%
1,75
87.500 US$
|
50 000
+833.3%
|
1,75
|
87.500 US$
|
|
|
2024-02-06 |
2024-02-06 |
S
Venta
|
Chief Financial Officer
Oficial
|
1 590
-7.1%
1,69
2.687 US$
|
1 590
-7.1%
|
1,69
|
2.687 US$
|
|
|
2023-12-12 |
2023-12-12 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
12 000
+12.7%
1,18
14.136 US$
|
12 000
+12.7%
|
1,18
|
14.136 US$
|
|
|
2023-12-12 |
2023-12-11 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
3 000
+3.3%
1,17
3.510 US$
|
3 000
+3.3%
|
1,17
|
3.510 US$
|
|
|
2023-11-13 |
2023-11-13 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
13 578
+17.5%
1,11
15.085 US$
|
13 578
+17.5%
|
1,11
|
15.085 US$
|
|
|
2023-11-13 |
2023-11-10 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
1 422
+1.9%
1,14
1.618 US$
|
1 422
+1.9%
|
1,14
|
1.618 US$
|
|
|
2023-08-01 |
2023-07-28 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
15 000
+24.5%
2,01
30.224 US$
|
15 000
+24.5%
|
2,01
|
30.224 US$
|
|
|
2023-05-11 |
2023-05-10 |
B
Compra
|
Consejero no ejecutivo
|
200 000
+177.0%
2,25
450.000 US$
|
200 000
+177.0%
|
2,25
|
450.000 US$
|
|
|
2023-02-06 |
2023-02-06 |
S
Venta
|
Chief Financial Officer
Oficial
|
1 566
-9.2%
2,36
3.696 US$
|
1 566
-9.2%
|
2,36
|
3.696 US$
|
|
|
2022-11-21 |
2022-11-21 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
10 000
+24.5%
2,14
21.405 US$
|
10 000
+24.5%
|
2,14
|
21.405 US$
|
|
|
2022-07-06 |
2022-07-01 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
15 000
+58.1%
2,88
43.164 US$
|
15 000
+58.1%
|
2,88
|
43.164 US$
|
|
|
2022-01-18 |
2022-01-13 |
PÁGINAS
Compra planificada
|
Chief Financial Officer
Oficial
|
1 923
+18.9%
6,75
12.980 US$
|
1 923
+18.9%
|
6,75
|
12.980 US$
|
|
|
2022-01-10 |
2022-01-07 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
5 000
+24.0%
6,76
33.806 US$
|
5 000
+24.0%
|
6,76
|
33.806 US$
|
|
|
2021-11-15 |
2021-11-15 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
2 500
+13.7%
8,58
21.438 US$
|
2 500
+13.7%
|
8,58
|
21.438 US$
|
|
|
2021-05-25 |
2021-05-21 |
S
Venta
|
Consejero no ejecutivo
|
2 500
-2.3%
4,34
10.850 US$
|
2 500
-2.3%
|
4,34
|
10.850 US$
|
|
|
2021-05-20 |
2021-05-18 |
B
Compra
|
Consejero no ejecutivo
|
50 000
+79.3%
3,98
199.000 US$
|
50 000
+79.3%
|
3,98
|
199.000 US$
|
|
|
2021-05-20 |
2021-05-18 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
10 000
+120.5%
4,01
40.100 US$
|
10 000
+120.5%
|
4,01
|
40.100 US$
|
|
|
2021-02-09 |
2021-02-09 |
S
Venta
|
President and CEO
Consejero ejecutivo
|
778
-8.6%
7,66
5.959 US$
|
778
-8.6%
|
7,66
|
5.959 US$
|
|
|
2021-02-09 |
2021-02-09 |
S
Venta
|
Chief Financial Officer
Oficial
|
390
-3.8%
7,66
2.987 US$
|
390
-3.8%
|
7,66
|
2.987 US$
|
|
|
2020-09-03 |
2020-09-02 |
S
Venta
|
Consejero no ejecutivo
|
7 260
-6.2%
4,01
29.113 US$
|
7 260
-6.2%
|
4,01
|
29.113 US$
|
|
|
2020-09-03 |
2020-08-28 |
S
Venta
|
Consejero no ejecutivo
|
100
-0.1%
4,00
400 US$
|
100
-0.1%
|
4,00
|
400 US$
|
|
|
2020-08-28 |
2020-08-27 |
S
Venta
|
Consejero no ejecutivo
|
5 440
-4.4%
4,09
22.250 US$
|
5 440
-4.4%
|
4,09
|
22.250 US$
|
|
|
2020-08-28 |
2020-08-26 |
S
Venta
|
Consejero no ejecutivo
|
2 200
-1.8%
4,30
9.451 US$
|
2 200
-1.8%
|
4,30
|
9.451 US$
|
|
|
2020-06-23 |
2020-06-19 |
B
Compra
|
Chief Financial Officer
Oficial
|
1 850
+25.3%
4,22
7.807 US$
|
1 850
+25.3%
|
4,22
|
7.807 US$
|
|
|
2020-06-23 |
2020-06-19 |
B
Compra
|
President and CEO
Consejero ejecutivo
|
6 000
+464.8%
4,27
25.620 US$
|
6 000
+464.8%
|
4,27
|
25.620 US$
|
|
|
2020-05-28 |
2020-05-20 |
Por favor
Venta prevista
|
General Counsel
Oficial
|
322
-10.5%
3,62
1.166 US$
|
322
-10.5%
|
3,62
|
1.166 US$
|
|
|
2020-05-22 |
2020-05-20 |
S
Venta
|
Consejero no ejecutivo
|
8 447
-1.9%
3,64
30.739 US$
|
8 447
-1.9%
|
3,64
|
30.739 US$
|
|
|
2020-02-11 |
2020-02-10 |
B
Compra
|
Consejero no ejecutivo
|
254 000
+138.4%
4,25
1.079.500 US$
|
254 000
+138.4%
|
4,25
|
1.079.500 US$
|
|
|
2020-02-07 |
2020-02-07 |
S
Venta
|
Chief Financial Officer
Oficial
|
375
-5.0%
4,03
1.511 US$
|
375
-5.0%
|
4,03
|
1.511 US$
|
|
|
2020-02-07 |
2020-02-07 |
S
Venta
|
President and CEO
Oficial
|
745
-36.6%
4,03
3.002 US$
|
745
-36.6%
|
4,03
|
3.002 US$
|
|
|
2019-05-20 |
2019-05-17 |
Por favor
Venta prevista
|
General Counsel
Oficial
|
4 651
-15.5%
0,45
2.093 US$
|
4 651
-15.5%
|
0,45
|
2.093 US$
|
|
|
2018-12-26 |
2018-12-21 |
B
Compra
|
MENDLEIN JOHN
Consejero no ejecutivo
|
195 000
+46.4%
0,42
82.602 US$
|
195 000
+46.4%
|
0,42
|
82.602 US$
|
|
|
2018-12-26 |
2018-12-20 |
B
Compra
|
MENDLEIN JOHN
Consejero no ejecutivo
|
50 000
+13.5%
0,41
20.645 US$
|
50 000
+13.5%
|
0,41
|
20.645 US$
|
|
|
2018-11-28 |
2018-11-26 |
B
Compra
|
SCHIMMEL PAUL
Consejero no ejecutivo
|
147 225
+20.0%
0,54
79.796 US$
|
147 225
+20.0%
|
0,54
|
79.796 US$
|
|
|
2018-09-21 |
2018-09-20 |
B
Compra
|
Broadfoot Jill Marie
Chief Financial Officer
Oficial
|
38 000
+73.1%
0,84
31.738 US$
|
38 000
+73.1%
|
0,84
|
31.738 US$
|
|
|
2018-09-21 |
2018-09-19 |
B
Compra
|
Broadfoot Jill Marie
Chief Financial Officer
Oficial
|
26 000
+100.0%
0,81
21.117 US$
|
26 000
+100.0%
|
0,81
|
21.117 US$
|
|
|
2018-09-18 |
2018-09-14 |
B
Compra
|
Broadfoot Jill Marie
Chief Financial Officer
Oficial
|
26 000
+inf%
0,73
19.055 US$
|
26 000
+inf%
|
0,73
|
19.055 US$
|
|
|
2018-09-05 |
2018-09-04 |
B
Compra
|
SCHIMMEL PAUL
Consejero no ejecutivo
|
20 749
+2.9%
0,76
15.709 US$
|
20 749
+2.9%
|
0,76
|
15.709 US$
|
|
|
2018-09-05 |
2018-08-31 |
B
Compra
|
SCHIMMEL PAUL
Consejero no ejecutivo
|
22 000
+3.2%
0,72
15.752 US$
|
22 000
+3.2%
|
0,72
|
15.752 US$
|
|
|
2018-08-31 |
2018-08-30 |
B
Compra
|
SCHIMMEL PAUL
Consejero no ejecutivo
|
89 275
+14.8%
0,76
67.483 US$
|
89 275
+14.8%
|
0,76
|
67.483 US$
|
|
|
2018-08-31 |
2018-08-29 |
B
Compra
|
SCHIMMEL PAUL
Consejero no ejecutivo
|
75 136
+14.2%
0,72
54.090 US$
|
75 136
+14.2%
|
0,72
|
54.090 US$
|
|
|
2018-05-21 |
2018-05-18 |
B
Compra
|
SCHIMMEL PAUL
Consejero no ejecutivo
|
150 000
+39.7%
1,00
149.445 US$
|
150 000
+39.7%
|
1,00
|
149.445 US$
|
|
|
2018-05-16 |
2018-05-16 |
S
Venta
|
EcoR1 Capital Fund Qualified, L.P.
Gran accionista
|
2 733 231
-100.0%
0,81
2.216.924 US$
|
2 733 231
-100.0%
|
0,81
|
2.216.924 US$
|
|
|
2018-05-16 |
2018-05-15 |
S
Venta
|
EcoR1 Capital Fund Qualified, L.P.
Gran accionista
|
121 294
-4.2%
1,43
173.062 US$
|
121 294
-4.2%
|
1,43
|
173.062 US$
|
|
|
2018-05-16 |
2018-05-14 |
S
Venta
|
EcoR1 Capital Fund Qualified, L.P.
Gran accionista
|
354 791
-11.1%
1,72
609.070 US$
|
354 791
-11.1%
|
1,72
|
609.070 US$
|
|
|
2018-02-08 |
2018-02-08 |
Por favor
Venta prevista
|
Blake John T
Senior Vice President, Finance
Oficial
|
1 402
-42.1%
3,40
4.767 US$
|
1 402
-42.1%
|
3,40
|
4.767 US$
|
|
|
2018-02-08 |
2018-02-08 |
Por favor
Venta prevista
|
See Remarks
Oficial
|
1 402
-42.1%
3,40
4.767 US$
|
1 402
-42.1%
|
3,40
|
4.767 US$
|
|
|
2017-12-14 |
2017-11-13 |
S
Venta
|
EcoR1 Capital Fund Qualified, L.P.
Gran accionista
|
1 083
-0.0%
3,95
4.278 US$
|
1 083
-0.0%
|
3,95
|
4.278 US$
|
|
|
2017-12-14 |
2017-11-10 |
S
Venta
|
EcoR1 Capital Fund Qualified, L.P.
Gran accionista
|
5 860
-0.2%
4,00
23.445 US$
|
5 860
-0.2%
|
4,00
|
23.445 US$
|
|
|
2017-12-14 |
2017-11-09 |
S
Venta
|
EcoR1 Capital Fund Qualified, L.P.
Gran accionista
|
5 819
-0.2%
4,15
24.151 US$
|
5 819
-0.2%
|
4,15
|
24.151 US$
|
|
|
2017-12-14 |
2017-11-08 |
S
Venta
|
EcoR1 Capital Fund Qualified, L.P.
Gran accionista
|
1 070
-0.0%
4,30
4.601 US$
|
1 070
-0.0%
|
4,30
|
4.601 US$
|
|
|
2017-12-14 |
2017-11-01 |
B
Compra
|
EcoR1 Capital Fund Qualified, L.P.
Gran accionista
|
24 728
+0.8%
4,80
118.694 US$
|
24 728
+0.8%
|
4,80
|
118.694 US$
|
|
|
2017-12-14 |
2017-10-01 |
B
Compra
|
EcoR1 Capital Fund Qualified, L.P.
Gran accionista
|
4 879
+0.2%
5,05
24.639 US$
|
4 879
+0.2%
|
5,05
|
24.639 US$
|
|
|
2017-09-05 |
2017-08-31 |
PÁGINAS
Compra planificada
|
MENDLEIN JOHN
CEO and Director
Consejero ejecutivo
|
37 736
+11.4%
2,65
100.000 US$
|
37 736
+11.4%
|
2,65
|
100.000 US$
|
|
|
2017-09-05 |
2017-08-31 |
B
Compra
|
SCHIMMEL PAUL
|
94 336
+33.3%
2,65
249.990 US$
|
94 336
+33.3%
|
2,65
|
249.990 US$
|
|
|
2017-04-26 |
2017-04-24 |
PÁGINAS
Compra planificada
|
MENDLEIN JOHN
CEO and Director
Consejero ejecutivo
|
124
+0.0%
3,00
372 US$
|
124
+0.0%
|
3,00
|
372 US$
|
|
|
2017-04-20 |
2017-04-20 |
PÁGINAS
Compra planificada
|
MENDLEIN JOHN
CEO and Director
Consejero ejecutivo
|
1 552
+0.5%
3,00
4.656 US$
|
1 552
+0.5%
|
3,00
|
4.656 US$
|
|