DENYES NANCY

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2026-02-04	2026-02-04	aTyr Pharma Inc (LIFE)	S Sale	74,446 +2.0% 406.01 US$1,297,114	74,446 +2.0%	406.01	US$1,297,114
2026-02-04	2026-02-04	aTyr Pharma Inc (LIFE)	S Sale	4,899 +13.1% 323.97 US$2,531,171	4,899 +13.1%	323.97	US$2,531,171
2025-02-04	2025-02-04	aTyr Pharma Inc (LIFE)	S Sale	79,616 +44.6% 324.21 US$2,973,546	79,616 +44.6%	324.21	US$2,973,546
2024-06-06	2024-06-05	aTyr Pharma Inc (LIFE)	B Purchase	5,000 +29.0% 1.86 US$9,276	5,000 +29.0%	1.86	US$9,276
2020-05-28	2020-05-20	aTyr Pharma Inc (LIFE)	PlS Planned sale	322 -10.5% 3.62 US$1,166	322 -10.5%	3.62	US$1,166
2019-05-20	2019-05-17	aTyr Pharma Inc (LIFE)	PlS Planned sale	4,651 -15.5% 0.45 US$2,093	4,651 -15.5%	0.45	US$2,093