Hanley Jr. Michael Conick

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2022-06-10	2022-06-08	Spyre Therapeutics Inc (SYRE)	PP Planned purchase	83,566 +49.5% 289.58 US$1,440,703	83,566 +49.5%	289.58	US$1,440,703