Cristina Larkin

Currently holds a position at Spero Therapeutics Inc

Position	Company	Period
Chief Operating Officer and Chief Commercial Officer	Spero Therapeutics Inc	Sept. 1, 2017 -
Chief Commercial Officer	Spero Therapeutics Inc	None -

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2020-12-18	2020-12-16	Spero Therapeutics Inc (SPRO)	PlS Planned sale	18,865 -1.6% 141.75 US$3,064,088	18,865 -1.6%	141.75	US$3,064,088