Mosbrooker Eric

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2025-10-07	2025-10-03	Avidity Biosciences Inc (RNA)	PlS Planned sale	52,860 -3.0% 294.09 US$2,534,971	52,860 -3.0%	294.09	US$2,534,971
2025-09-05	2025-09-03	Avidity Biosciences Inc (RNA)	PlS Planned sale	52,278 +21.3% 360.79 US$1,240,711	52,278 +21.3%	360.79	US$1,240,711
2025-09-03	2025-09-03	Avidity Biosciences Inc (RNA)	PrS Proposed sale	59,948 12.62 US$2,964,296	59,948	12.62	US$2,964,296
2025-08-08	2025-08-06	Avidity Biosciences Inc (RNA)	PlS Planned sale	6,120 -10.0% 44.06 US$269,663	6,120 -10.0%	44.06	US$269,663
2025-08-08	2025-08-06	Avidity Biosciences Inc (RNA)	PlS Planned sale	124,687 -67.1% 44.06 US$5,494,033	124,687 -67.1%	44.06	US$5,494,033
2025-08-06	2025-08-06	Avidity Biosciences Inc (RNA)	PrS Proposed sale	130,807 38.26 US$5,004,676	130,807	38.26	US$5,004,676