Guy Chatelain

2.9

2.9

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2018-01-03	2017-12-29	Ose Immunotherapeutics SA (OSE)	S Sale	18,794 77.04 €3,560,619	18,794	77.04	€3,560,619
2018-01-03	2017-12-29	Ose Immunotherapeutics SA (OSE)	S Sale	68,127 418.34 €2,060,475	68,127	418.34	€2,060,475
2017-12-28	2017-12-27	Ose Immunotherapeutics SA (OSE)	S Sale	36,784 265.53 €1,859,714	36,784	265.53	€1,859,714
2017-12-15	2017-12-13	Ose Immunotherapeutics SA (OSE)	S Sale	1,300 3.75 €4,877	1,300	3.75	€4,877
2017-12-14	2017-12-12	Ose Immunotherapeutics SA (OSE)	S Sale	1,000 3.91 €3,912	1,000	3.91	€3,912
2017-01-31	2017-01-26	Ose Immunotherapeutics SA (OSE)	S Sale	2,000 6.93 €13,850	2,000	6.93	€13,850