|
Nov. 4, 2022 |
Nov. 3, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
1,262
+1.0%
7.81
9,859
USD
|
1,262
+1.0%
|
7.81
|
9,859
USD
|
|
|
Nov. 4, 2022 |
Nov. 3, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
19,000
+1.0%
7.81
148,426
USD
|
19,000
+1.0%
|
7.81
|
148,426
USD
|
|
|
Oct. 11, 2022 |
Oct. 11, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
1,000
+0.8%
8.00
8,000
USD
|
1,000
+0.8%
|
8.00
|
8,000
USD
|
|
|
Oct. 11, 2022 |
Oct. 11, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
15,000
+0.8%
8.00
120,000
USD
|
15,000
+0.8%
|
8.00
|
120,000
USD
|
|
|
Sept. 26, 2022 |
Sept. 23, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
304
+0.2%
7.99
2,430
USD
|
304
+0.2%
|
7.99
|
2,430
USD
|
|
|
Sept. 26, 2022 |
Sept. 23, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
6,500
+0.3%
7.99
51,962
USD
|
6,500
+0.3%
|
7.99
|
51,962
USD
|
|
|
Sept. 19, 2022 |
Sept. 19, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
1,000
+0.8%
8.09
8,088
USD
|
1,000
+0.8%
|
8.09
|
8,088
USD
|
|
|
Sept. 19, 2022 |
Sept. 19, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
17,000
+0.9%
8.09
137,496
USD
|
17,000
+0.9%
|
8.09
|
137,496
USD
|
|
|
Sept. 16, 2022 |
Sept. 16, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
372
+0.3%
8.08
3,007
USD
|
372
+0.3%
|
8.08
|
3,007
USD
|
|
|
Sept. 16, 2022 |
Sept. 16, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
2,000
+0.1%
8.08
16,166
USD
|
2,000
+0.1%
|
8.08
|
16,166
USD
|
|
|
Sept. 16, 2022 |
Sept. 15, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
658
+0.5%
8.10
5,330
USD
|
658
+0.5%
|
8.10
|
5,330
USD
|
|
|
Sept. 16, 2022 |
Sept. 15, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
3,500
+0.2%
8.10
28,350
USD
|
3,500
+0.2%
|
8.10
|
28,350
USD
|
|
|
Aug. 19, 2022 |
Aug. 17, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
500,000
+13.9%
8.00
4,000,000
USD
|
500,000
+13.9%
|
8.00
|
4,000,000
USD
|
|
|
Sept. 15, 2022 |
Aug. 16, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
221
+0.2%
8.10
1,790
USD
|
221
+0.2%
|
8.10
|
1,790
USD
|
|
|
Sept. 15, 2022 |
Aug. 16, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
5,000
+0.3%
8.10
40,496
USD
|
5,000
+0.3%
|
8.10
|
40,496
USD
|
|
|
Aug. 16, 2022 |
Aug. 16, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
15,000
+14.3%
8.00
120,000
USD
|
15,000
+14.3%
|
8.00
|
120,000
USD
|
|
|
Aug. 16, 2022 |
Aug. 16, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
300,000
+19.0%
8.00
2,400,000
USD
|
300,000
+19.0%
|
8.00
|
2,400,000
USD
|
|
|
Aug. 12, 2022 |
Aug. 10, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
479
+0.5%
8.52
4,082
USD
|
479
+0.5%
|
8.52
|
4,082
USD
|
|
|
Aug. 12, 2022 |
Aug. 10, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
11,500
+0.7%
8.52
98,006
USD
|
11,500
+0.7%
|
8.52
|
98,006
USD
|
|
|
Aug. 2, 2022 |
Aug. 1, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
479
+0.5%
7.96
3,813
USD
|
479
+0.5%
|
7.96
|
3,813
USD
|
|
|
Aug. 2, 2022 |
Aug. 1, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
4,500
+0.3%
7.96
35,819
USD
|
4,500
+0.3%
|
7.96
|
35,819
USD
|
|
|
July 22, 2022 |
July 22, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
200
+0.2%
8.02
1,604
USD
|
200
+0.2%
|
8.02
|
1,604
USD
|
|
|
July 22, 2022 |
July 22, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
5,000
+0.3%
8.02
40,105
USD
|
5,000
+0.3%
|
8.02
|
40,105
USD
|
|
|
July 21, 2022 |
July 21, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
833
+0.8%
8.08
6,728
USD
|
833
+0.8%
|
8.08
|
6,728
USD
|
|
|
July 21, 2022 |
July 21, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
9,500
+0.6%
8.03
76,282
USD
|
9,500
+0.6%
|
8.03
|
76,282
USD
|
|
|
July 20, 2022 |
July 20, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
600
+0.6%
8.08
4,846
USD
|
600
+0.6%
|
8.08
|
4,846
USD
|
|
|
July 20, 2022 |
July 20, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
4,500
+0.3%
8.08
36,346
USD
|
4,500
+0.3%
|
8.08
|
36,346
USD
|
|
|
July 13, 2022 |
July 13, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.03
40,150
USD
|
5,000
+0.1%
|
8.03
|
40,150
USD
|
|
|
July 13, 2022 |
July 12, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.02
40,100
USD
|
5,000
+0.1%
|
8.02
|
40,100
USD
|
|
|
July 13, 2022 |
July 11, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.02
40,100
USD
|
5,000
+0.1%
|
8.02
|
40,100
USD
|
|
|
July 8, 2022 |
July 8, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.96
39,800
USD
|
5,000
+0.1%
|
7.96
|
39,800
USD
|
|
|
July 8, 2022 |
July 7, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.07
40,350
USD
|
5,000
+0.1%
|
8.07
|
40,350
USD
|
|
|
July 8, 2022 |
July 6, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.86
39,300
USD
|
5,000
+0.1%
|
7.86
|
39,300
USD
|
|
|
July 5, 2022 |
July 5, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.52
37,600
USD
|
5,000
+0.1%
|
7.52
|
37,600
USD
|
|
|
July 5, 2022 |
July 1, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
200
+0.2%
7.00
1,400
USD
|
200
+0.2%
|
7.00
|
1,400
USD
|
|
|
July 5, 2022 |
July 1, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.27
36,350
USD
|
5,000
+0.1%
|
7.27
|
36,350
USD
|
|
|
July 5, 2022 |
June 30, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.07
35,350
USD
|
5,000
+0.1%
|
7.07
|
35,350
USD
|
|
|
June 29, 2022 |
June 28, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.10
35,500
USD
|
5,000
+0.1%
|
7.10
|
35,500
USD
|
|
|
June 29, 2022 |
June 28, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.09
35,450
USD
|
5,000
+0.1%
|
7.09
|
35,450
USD
|
|
|
June 29, 2022 |
June 27, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.22
36,100
USD
|
5,000
+0.1%
|
7.22
|
36,100
USD
|
|
|
June 24, 2022 |
June 24, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.06
35,300
USD
|
5,000
+0.1%
|
7.06
|
35,300
USD
|
|
|
June 24, 2022 |
June 23, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.99
34,950
USD
|
5,000
+0.1%
|
6.99
|
34,950
USD
|
|
|
June 24, 2022 |
June 22, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
400
+0.4%
6.99
2,796
USD
|
400
+0.4%
|
6.99
|
2,796
USD
|
|
|
June 24, 2022 |
June 22, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
2,000
+0.1%
6.99
13,980
USD
|
2,000
+0.1%
|
6.99
|
13,980
USD
|
|
|
June 24, 2022 |
June 22, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.47
32,350
USD
|
5,000
+0.1%
|
6.47
|
32,350
USD
|
|
|
June 22, 2022 |
June 22, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
50,000
+3.4%
6.50
324,975
USD
|
50,000
+3.4%
|
6.50
|
324,975
USD
|
|
|
June 21, 2022 |
June 21, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.25
31,250
USD
|
5,000
+0.1%
|
6.25
|
31,250
USD
|
|
|
June 21, 2022 |
June 17, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.17
30,850
USD
|
5,000
+0.1%
|
6.17
|
30,850
USD
|
|
|
June 21, 2022 |
June 16, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.01
30,050
USD
|
5,000
+0.1%
|
6.01
|
30,050
USD
|
|
|
June 15, 2022 |
June 15, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
5.90
29,500
USD
|
5,000
+0.1%
|
5.90
|
29,500
USD
|
|
|
June 15, 2022 |
June 14, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
5.86
29,300
USD
|
5,000
+0.1%
|
5.86
|
29,300
USD
|
|
|
June 15, 2022 |
June 13, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
5.81
29,050
USD
|
5,000
+0.1%
|
5.81
|
29,050
USD
|
|
|
June 22, 2022 |
June 10, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
2,400
+2.5%
6.50
15,599
USD
|
2,400
+2.5%
|
6.50
|
15,599
USD
|
|
|
June 10, 2022 |
June 10, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
5.80
29,000
USD
|
5,000
+0.1%
|
5.80
|
29,000
USD
|
|
|
June 10, 2022 |
June 10, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
2,500
+2.7%
5.60
14,006
USD
|
2,500
+2.7%
|
5.60
|
14,006
USD
|
|
|
June 10, 2022 |
June 10, 2022 |
B
Purchase
|
Opaleye Management Inc.
Major owner
|
25,000
+1.7%
5.60
140,060
USD
|
25,000
+1.7%
|
5.60
|
140,060
USD
|
|
|
June 10, 2022 |
June 9, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.17
30,850
USD
|
5,000
+0.1%
|
6.17
|
30,850
USD
|
|
|
June 10, 2022 |
June 8, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
5.98
29,900
USD
|
5,000
+0.1%
|
5.98
|
29,900
USD
|
|
|
June 7, 2022 |
June 7, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
5.53
27,650
USD
|
5,000
+0.1%
|
5.53
|
27,650
USD
|
|
|
June 7, 2022 |
June 7, 2022 |
B
Purchase
|
Cuca Roberto
COO and CFO
Officer
|
15,000
+75.4%
5.50
82,500
USD
|
15,000
+75.4%
|
5.50
|
82,500
USD
|
|
|
June 7, 2022 |
June 6, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
5.99
29,950
USD
|
5,000
+0.1%
|
5.99
|
29,950
USD
|
|
|
June 7, 2022 |
June 3, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.86
34,300
USD
|
5,000
+0.1%
|
6.86
|
34,300
USD
|
|
|
June 2, 2022 |
June 2, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.99
34,950
USD
|
5,000
+0.1%
|
6.99
|
34,950
USD
|
|
|
June 2, 2022 |
June 1, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.88
34,400
USD
|
5,000
+0.1%
|
6.88
|
34,400
USD
|
|
|
June 2, 2022 |
May 31, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.11
35,550
USD
|
5,000
+0.1%
|
7.11
|
35,550
USD
|
|
|
May 27, 2022 |
May 27, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.43
37,150
USD
|
5,000
+0.1%
|
7.43
|
37,150
USD
|
|
|
May 27, 2022 |
May 26, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.04
35,200
USD
|
5,000
+0.1%
|
7.04
|
35,200
USD
|
|
|
May 27, 2022 |
May 25, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
6.87
34,350
USD
|
5,000
+0.1%
|
6.87
|
34,350
USD
|
|
|
May 24, 2022 |
May 24, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
7.19
35,950
USD
|
5,000
+0.1%
|
7.19
|
35,950
USD
|
|
|
May 24, 2022 |
May 23, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.53
42,650
USD
|
5,000
+0.1%
|
8.53
|
42,650
USD
|
|
|
May 24, 2022 |
May 20, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.79
43,950
USD
|
5,000
+0.1%
|
8.79
|
43,950
USD
|
|
|
May 19, 2022 |
May 19, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.99
44,950
USD
|
5,000
+0.1%
|
8.99
|
44,950
USD
|
|
|
May 19, 2022 |
May 18, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.96
44,800
USD
|
5,000
+0.1%
|
8.96
|
44,800
USD
|
|
|
May 19, 2022 |
May 17, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.94
44,700
USD
|
5,000
+0.1%
|
8.94
|
44,700
USD
|
|
|
May 16, 2022 |
May 16, 2022 |
B
Purchase
|
EW HEALTHCARE PARTNERS FUND 2, L.P.
See footnote 2
|
5,000
+0.1%
8.61
43,050
USD
|
5,000
+0.1%
|
8.61
|
43,050
USD
|
|
