United States Biotechnology & Medical Research

Rigel Pharmaceuticals Inc (RIGL)

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Rigel Pharmaceuticals witnessed three insider trading transactions over the past ninety days, totaling 262,500 dollars in sales. These divestments occurred amidst a 30.5 percent stock price increase. Following the most recent earnings report, which missed expectations by 3.29 percent, market participants continue monitoring executive activity closely as the firm approaches its next scheduled financial disclosure.
Ticker: RIGL Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Rigel Pharmaceuticals Inc. Upgrade to see score, net flow, insiders and the full signal context.

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Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
3.2
Ali-Jackson Kamil Non-Executive Director
Transaction date
Planned sale
Price
59.05
Quantity 92,486 -25.3%
Value US$1,041,116
3.2
Ali-Jackson Kamil Director Non-Executive Director
Transaction date
Proposed sale
Price
218.19
Quantity 79,403
Value US$2,167,933
3.2
Ali-Jackson Kamil Director Non-Executive Director
Transaction date
Proposed sale
Price
177.27
Quantity 93,815
Value US$2,313,490
3.2
Ali-Jackson Kamil Non-Executive Director
Transaction date
Planned sale
Price
29.17
Quantity 2,500 -16.5%
Value US$72,925
3.2
Ali-Jackson Kamil Director Non-Executive Director
Transaction date
Proposed sale
Price
29.17
Quantity 2,500
Value US$72,925
3.0
MOOS WALTER H Non-Executive Director
Transaction date
Sale
Price
36.36
Quantity 4,000 -23.9%
Value US$145,440
3.0
MOOS WALTER H Director Non-Executive Director
Transaction date
Proposed sale
Price
36.36
Quantity 4,000
Value US$145,440
3.4
Santos David A EVP, Chief Commercial Officer Officer
Transaction date
Sale
Price
21.93
Quantity 1,796 -3.4%
Value US$39,379
3.1
Furey Raymond J. EVP, GC, CCO & Corp Sec Officer
Transaction date
Sale
Price
21.93
Quantity 1,339 -3.3%
Value US$29,359
4.1
RODRIGUEZ RAUL R CEO, President Executive Director
Transaction date
Sale
Price
21.93
Quantity 4,400 -1.8%
Value US$96,474
2.6
Schorno Dean L EVP & Chief Financial Officer Officer
Transaction date
Sale
Price
21.93
Quantity 1,734 -2.9%
Value US$38,020
3.4
Santos David A Officer Officer
Transaction date
Proposed sale
Price
21.93
Quantity 1,796
Value US$39,379
2.6
Schorno Dean L Officer Officer
Transaction date
Proposed sale
Price
21.93
Quantity 1,734
Value US$38,020
3.1
Furey Raymond J. Officer Officer
Transaction date
Proposed sale
Price
21.93
Quantity 1,339
Value US$29,359
4.1
RODRIGUEZ RAUL R Officer; Director Executive Director
Transaction date
Proposed sale
Price
21.93
Quantity 4,400
Value US$96,474
3.4
Santos David A EVP, Chief Commercial Officer Officer
Transaction date
Sale
Price
20.92
Quantity 2,125 -3.8%
Value US$44,457
3.1
Furey Raymond J. EVP, GC, CCO & Corp Sec Officer
Transaction date
Sale
Price
20.92
Quantity 1,448 -3.5%
Value US$30,294
4.1
RODRIGUEZ RAUL R CEO, President Executive Director
Transaction date
Sale
Price
20.92
Quantity 4,952 -2.0%
Value US$103,601
2.6
Schorno Dean L EVP & Chief Financial Officer Officer
Transaction date
Sale
Price
20.92
Quantity 2,036 -3.3%
Value US$42,595
2.6
Schorno Dean L Officer Officer
Transaction date
Proposed sale
Price
20.92
Quantity 2,036
Value US$42,596
4.1
RODRIGUEZ RAUL R Officer; Director Executive Director
Transaction date
Proposed sale
Price
20.92
Quantity 4,952
Value US$103,602
3.1
Furey Raymond J. Officer Officer
Transaction date
Proposed sale
Price
20.92
Quantity 1,448
Value US$30,294
3.4
Santos David A Officer Officer
Transaction date
Proposed sale
Price
20.92
Quantity 2,125
Value US$44,458
Masuda Esteban Officer Officer
Transaction date
Proposed sale
Price
22.14
Quantity 4,999
Value US$110,678
4.1
RODRIGUEZ RAUL R CEO, President Executive Director
Transaction date
Sale
Price
1.14
Quantity 30,545 -1.5%
Value US$34,821
2.6
Schorno Dean L EVP & Chief Financial Officer Officer
Transaction date
Sale
Price
1.14
Quantity 7,027 -1.7%
Value US$8,011
3.4
Santos David A EVP, Chief Commercial Officer Officer
Transaction date
Sale
Price
1.14
Quantity 8,918 -2.5%
Value US$10,167
4.1
RODRIGUEZ RAUL R CEO, President Executive Director
Transaction date
Sale
Price
1.13
Quantity 22,349 -1.1%
Value US$25,261
2.6
Schorno Dean L EVP & Chief Financial Officer Officer
Transaction date
Sale
Price
1.13
Quantity 5,601 -1.3%
Value US$6,327
3.4
Santos David A EVP, Chief Commercial Officer Officer
Transaction date
Sale
Price
1.13
Quantity 5,601 -1.5%
Value US$6,329
4.1
RODRIGUEZ RAUL R CEO, President Executive Director
Transaction date
Sale
Price
1.75
Quantity 20,340 -1.2%
Value US$35,595
2.6
Schorno Dean L EVP & Chief Financial Officer Officer
Transaction date
Sale
Price
1.66
Quantity 5,389 -2.7%
Value US$8,946
3.4
Santos David A EVP, Chief Commercial Officer Officer
Transaction date
Sale
Price
1.66
Quantity 5,388 -3.6%
Value US$8,945
3.1
Dummer Wolfgang EVP & CMO Officer
Transaction date
Sale
Price
1.66
Quantity 5,389 -6.9%
Value US$8,946
4.1
RODRIGUEZ RAUL R CEO, President Executive Director
Transaction date
Purchase
Price
0.69
Quantity 1,000,000 +255.2%
Value US$688,400
2.6
Schorno Dean L EVP &Chief Financial Officer Officer
Transaction date
Purchase
Price
2.13
Quantity 3,274 +7.0%
Value US$6,971
2.6
Schorno Dean L EVP &Chief Financial Officer Officer
Transaction date
Purchase
Price
2.13
Quantity 46,726 +inf%
Value US$99,573
Cabatuan Nelson Principal Accounting Officer Officer
Transaction date
Planned sale
Price
3.12
Quantity 10,000 -99.4%
Value US$31,200
Duliege Anne-Marie EVP & Chief Medical Officer Officer
Transaction date
Planned sale
Price
3.50
Quantity 37,500 -100.0%
Value US$131,250
Duliege Anne-Marie EVP & Chief Medical Officer Officer
Transaction date
Planned sale
Price
3.50
Quantity 115,500 -100.0%
Value US$404,250
Mayer Eldon C. III EVP & Chief Commercial Officer Officer
Transaction date
Purchase
Price
3.23
Quantity 50,000 +30.3%
Value US$161,340
Mayer Eldon C. III EVP & Chief Commercial Officer Officer
Transaction date
Purchase
Price
3.28
Quantity 50,000 +43.5%
Value US$164,210
Duliege Anne-Marie EVP & Chief Medical Officer Officer
Transaction date
Planned sale
Price
3.51
Quantity 16,500 -100.0%
Value US$57,861
Mayer Eldon C. III EVP & Chief Commercial Officer Officer
Transaction date
Planned purchase
Price
2.82
Quantity 100,000 +666.7%
Value US$282,320
RODRIGUEZ RAUL R CEO, President Executive Director
Transaction date
Planned purchase
Price
2.63
Quantity 114,000 +191.5%
Value US$300,002
Duliege Anne-Marie EVP & Chief Medical Officer Officer
Transaction date
Planned sale
Price
2.79
Quantity 5,000 -100.0%
Value US$13,932
Duliege Anne-Marie EVP & Chief Medical Officer
Transaction date
Planned sale
Price
4.11
Quantity 5,000 -100.0%
Value US$20,550
Maynard Ryan D EVP & CFO
Transaction date
Planned sale
Price
3.90
Quantity 100,000 -100.0%
Value US$390,000
Duliege Anne-Marie Chief Medical Officer Officer
Transaction date
Planned sale
Price
2.69
Quantity 5,000 -100.0%
Value US$13,427
Duliege Anne-Marie Chief Medical Officer Officer
Transaction date
Planned sale
Price
2.41
Quantity 5,000 -100.0%
Value US$12,028
PAYAN DONALD G EVP, Pres. Discovery&Research Executive Director
Transaction date
Planned sale
Price
4.00
Quantity 5,303 -9.1%
Value US$21,214
PAYAN DONALD G EVP, Pres. Discovery&Research Executive Director
Transaction date
Sale
Price
3.68
Quantity 41,666 -41.7%
Value US$153,214
PAYAN DONALD G EVP, Pres. Discovery&Research Executive Director
Transaction date
Sale
Price
3.75
Quantity 10,000 -14.6%
Value US$37,518
PAYAN DONALD G EVP, Pres. Discovery&Research Executive Director
Transaction date
Sale
Price
2.56
Quantity 20,000 -22.6%
Value US$51,200
PAYAN DONALD G EVP, Pres. Discovery&Research Executive Director
Transaction date
Sale
Price
3.71
Quantity 20,000 -18.5%
Value US$74,238
BVF PARTNERS L P/IL See Explanation of Responses Large shareholder
Transaction date
Sale
Price
2.64
Quantity 153,056 -19.1%
Value US$404,343
BVF PARTNERS L P/IL See Explanation of Responses Large shareholder
Transaction date
Sale
Price
2.64
Quantity 331,566 -22.8%
Value US$875,931
BVF PARTNERS L P/IL See Explanation of Responses Large shareholder
Transaction date
Purchase
Price
3.47
Quantity 8,102 +1.0%
Value US$28,095
BVF PARTNERS L P/IL See Explanation of Responses Large shareholder
Transaction date
Purchase
Price
3.47
Quantity 24,598 +1.7%
Value US$85,298
VANCE DOLLY EVP Corp. Affairs, G.C., Sect. Officer
Transaction date
Sale
Price
10.43
Quantity 4,151 -79.0%
Value US$43,284
Maynard Ryan D EVP & CFO Officer
Transaction date
Sale
Price
10.52
Quantity 17,586 -100.0%
Value US$184,927
Maynard Ryan D EVP & CFO Officer
Transaction date
Sale
Price
10.67
Quantity 23,302 -100.0%
Value US$248,560
Maynard Ryan D EVP & CFO Officer
Transaction date
Sale
Price
10.55
Quantity 34,112 -100.0%
Value US$359,960
Maynard Ryan D EVP & CFO Officer
Transaction date
Sale
Price
10.63
Quantity 300 -100.0%
Value US$3,188
Maynard Ryan D EVP & CFO Officer
Transaction date
Sale
Price
10.62
Quantity 600 -66.7%
Value US$6,372
Maynard Ryan D EVP & CFO Officer
Transaction date
Sale
Price
10.61
Quantity 100 -10.0%
Value US$1,061
Maynard Ryan D EVP & CFO Officer
Transaction date
Sale
Price
10.60
Quantity 700 -41.2%
Value US$7,420
PAYAN DONALD G EVP, Pres. Discovery&Research Executive Director
Transaction date
Sale
Price
8.71
Quantity 100 -0.1%
Value US$871
PAYAN DONALD G EVP, Pres. Discovery&Research Executive Director
Transaction date
Sale
Price
8.70
Quantity 9,700 -8.2%
Value US$84,390
PAYAN DONALD G EVP, Pres. Discovery&Research Executive Director
Transaction date
Sale
Price
8.72
Quantity 100 -0.1%
Value US$872
PAYAN DONALD G EVP, Pres. Discovery&Research Executive Director
Transaction date
Sale
Price
8.75
Quantity 100 -0.1%
Value US$875
Flynn James E Large shareholder
Transaction date
Purchase
Price
8.00
Quantity 301,424 +10.4%
Value US$2,411,392
Flynn James E Large shareholder
Transaction date
Purchase
Price
8.00
Quantity 229,252 +11.2%
Value US$1,834,016
Flynn James E Large shareholder
Transaction date
Purchase
Price
8.00
Quantity 72,800 +10.6%
Value US$582,400
Flynn James E Large shareholder
Transaction date
Purchase
Price
8.00
Quantity 46,524 +11.0%
Value US$372,192
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-06-24 2026-06-22 PlS Planned sale
3.2
Ali-Jackson Kamil
Non-Executive Director
92,486 -25.3%
59.05
US$1,041,116 		92,486 -25.3% 59.05 US$1,041,116
2026-06-22 2026-06-22 PrS Proposed sale
3.2
Ali-Jackson Kamil

Director

Non-Executive Director
79,403
218.19
US$2,167,933 		79,403 218.19 US$2,167,933
2026-06-22 2026-06-22 PrS Proposed sale
3.2
Ali-Jackson Kamil

Director

Non-Executive Director
93,815
177.27
US$2,313,490 		93,815 177.27 US$2,313,490
2026-05-28 2026-05-26 PlS Planned sale
3.2
Ali-Jackson Kamil
Non-Executive Director
2,500 -16.5%
29.17
US$72,925 		2,500 -16.5% 29.17 US$72,925
2026-05-26 2026-05-26 PrS Proposed sale
3.2
Ali-Jackson Kamil

Director

Non-Executive Director
2,500
29.17
US$72,925 		2,500 29.17 US$72,925
2026-02-24 2026-02-20 S Sale
3.0
MOOS WALTER H
Non-Executive Director
4,000 -23.9%
36.36
US$145,440 		4,000 -23.9% 36.36 US$145,440
2026-02-20 2026-02-20 PrS Proposed sale
3.0
MOOS WALTER H

Director

Non-Executive Director
4,000
36.36
US$145,440 		4,000 36.36 US$145,440
2025-02-06 2025-02-05 S Sale
3.4
Santos David A

EVP, Chief Commercial Officer

Officer
1,796 -3.4%
21.93
US$39,379 		1,796 -3.4% 21.93 US$39,379
2025-02-06 2025-02-05 S Sale
3.1
Furey Raymond J.

EVP, GC, CCO & Corp Sec

Officer
1,339 -3.3%
21.93
US$29,359 		1,339 -3.3% 21.93 US$29,359
2025-02-06 2025-02-05 S Sale
4.1
RODRIGUEZ RAUL R

CEO, President

Executive Director
4,400 -1.8%
21.93
US$96,474 		4,400 -1.8% 21.93 US$96,474
2025-02-06 2025-02-05 S Sale
2.6
Schorno Dean L

EVP & Chief Financial Officer

Officer
1,734 -2.9%
21.93
US$38,020 		1,734 -2.9% 21.93 US$38,020
2025-02-05 2025-02-05 PrS Proposed sale
3.4
Santos David A

Officer

Officer
1,796
21.93
US$39,379 		1,796 21.93 US$39,379
2025-02-05 2025-02-05 PrS Proposed sale
2.6
Schorno Dean L

Officer

Officer
1,734
21.93
US$38,020 		1,734 21.93 US$38,020
2025-02-05 2025-02-05 PrS Proposed sale
3.1
Furey Raymond J.

Officer

Officer
1,339
21.93
US$29,359 		1,339 21.93 US$29,359
2025-02-05 2025-02-05 PrS Proposed sale
4.1
RODRIGUEZ RAUL R

Officer; Director

Executive Director
4,400
21.93
US$96,474 		4,400 21.93 US$96,474
2025-02-06 2025-02-04 S Sale
3.4
Santos David A

EVP, Chief Commercial Officer

Officer
2,125 -3.8%
20.92
US$44,457 		2,125 -3.8% 20.92 US$44,457
2025-02-06 2025-02-04 S Sale
3.1
Furey Raymond J.

EVP, GC, CCO & Corp Sec

Officer
1,448 -3.5%
20.92
US$30,294 		1,448 -3.5% 20.92 US$30,294
2025-02-06 2025-02-04 S Sale
4.1
RODRIGUEZ RAUL R

CEO, President

Executive Director
4,952 -2.0%
20.92
US$103,601 		4,952 -2.0% 20.92 US$103,601
2025-02-06 2025-02-04 S Sale
2.6
Schorno Dean L

EVP & Chief Financial Officer

Officer
2,036 -3.3%
20.92
US$42,595 		2,036 -3.3% 20.92 US$42,595
2025-02-04 2025-02-04 PrS Proposed sale
2.6
Schorno Dean L

Officer

Officer
2,036
20.92
US$42,596 		2,036 20.92 US$42,596
2025-02-04 2025-02-04 PrS Proposed sale
4.1
RODRIGUEZ RAUL R

Officer; Director

Executive Director
4,952
20.92
US$103,602 		4,952 20.92 US$103,602
2025-02-04 2025-02-04 PrS Proposed sale
3.1
Furey Raymond J.

Officer

Officer
1,448
20.92
US$30,294 		1,448 20.92 US$30,294
2025-02-04 2025-02-04 PrS Proposed sale
3.4
Santos David A

Officer

Officer
2,125
20.92
US$44,458 		2,125 20.92 US$44,458
2025-01-24 2025-01-24 PrS Proposed sale
Masuda Esteban

Officer

Officer
4,999
22.14
US$110,678 		4,999 22.14 US$110,678
2024-02-06 2024-02-05 S Sale
4.1
RODRIGUEZ RAUL R

CEO, President

Executive Director
30,545 -1.5%
1.14
US$34,821 		30,545 -1.5% 1.14 US$34,821
2024-02-06 2024-02-05 S Sale
2.6
Schorno Dean L

EVP & Chief Financial Officer

Officer
7,027 -1.7%
1.14
US$8,011 		7,027 -1.7% 1.14 US$8,011
2024-02-06 2024-02-05 S Sale
3.4
Santos David A

EVP, Chief Commercial Officer

Officer
8,918 -2.5%
1.14
US$10,167 		8,918 -2.5% 1.14 US$10,167
2024-02-06 2024-02-02 S Sale
4.1
RODRIGUEZ RAUL R

CEO, President

Executive Director
22,349 -1.1%
1.13
US$25,261 		22,349 -1.1% 1.13 US$25,261
2024-02-06 2024-02-02 S Sale
2.6
Schorno Dean L

EVP & Chief Financial Officer

Officer
5,601 -1.3%
1.13
US$6,327 		5,601 -1.3% 1.13 US$6,327
2024-02-06 2024-02-02 S Sale
3.4
Santos David A

EVP, Chief Commercial Officer

Officer
5,601 -1.5%
1.13
US$6,329 		5,601 -1.5% 1.13 US$6,329
2023-02-07 2023-02-06 S Sale
4.1
RODRIGUEZ RAUL R

CEO, President

Executive Director
20,340 -1.2%
1.75
US$35,595 		20,340 -1.2% 1.75 US$35,595
2023-02-06 2023-02-02 S Sale
2.6
Schorno Dean L

EVP & Chief Financial Officer

Officer
5,389 -2.7%
1.66
US$8,946 		5,389 -2.7% 1.66 US$8,946
2023-02-06 2023-02-02 S Sale
3.4
Santos David A

EVP, Chief Commercial Officer

Officer
5,388 -3.6%
1.66
US$8,945 		5,388 -3.6% 1.66 US$8,945
2023-02-06 2023-02-02 S Sale
3.1
Dummer Wolfgang

EVP & CMO

Officer
5,389 -6.9%
1.66
US$8,946 		5,389 -6.9% 1.66 US$8,946
2022-06-13 2022-06-09 B Purchase
4.1
RODRIGUEZ RAUL R

CEO, President

Executive Director
1,000,000 +255.2%
0.69
US$688,400 		1,000,000 +255.2% 0.69 US$688,400
2019-05-23 2019-05-22 B Purchase
2.6
Schorno Dean L

EVP &Chief Financial Officer

Officer
3,274 +7.0%
2.13
US$6,971 		3,274 +7.0% 2.13 US$6,971
2019-05-23 2019-05-22 B Purchase
2.6
Schorno Dean L

EVP &Chief Financial Officer

Officer
46,726 +inf%
2.13
US$99,573 		46,726 +inf% 2.13 US$99,573
2018-10-16 2018-10-12 PlS Planned sale Cabatuan Nelson

Principal Accounting Officer

Officer
10,000 -99.4%
3.12
US$31,200 		10,000 -99.4% 3.12 US$31,200
2018-09-19 2018-09-17 PlS Planned sale Duliege Anne-Marie

EVP & Chief Medical Officer

Officer
37,500 -100.0%
3.50
US$131,250 		37,500 -100.0% 3.50 US$131,250
2018-09-19 2018-09-17 PlS Planned sale Duliege Anne-Marie

EVP & Chief Medical Officer

Officer
115,500 -100.0%
3.50
US$404,250 		115,500 -100.0% 3.50 US$404,250
2018-09-12 2018-09-11 B Purchase Mayer Eldon C. III

EVP & Chief Commercial Officer

Officer
50,000 +30.3%
3.23
US$161,340 		50,000 +30.3% 3.23 US$161,340
2018-09-12 2018-09-10 B Purchase Mayer Eldon C. III

EVP & Chief Commercial Officer

Officer
50,000 +43.5%
3.28
US$164,210 		50,000 +43.5% 3.28 US$164,210
2018-09-06 2018-09-04 PlS Planned sale Duliege Anne-Marie

EVP & Chief Medical Officer

Officer
16,500 -100.0%
3.51
US$57,861 		16,500 -100.0% 3.51 US$57,861
2018-08-27 2018-08-23 PP Planned purchase Mayer Eldon C. III

EVP & Chief Commercial Officer

Officer
100,000 +666.7%
2.82
US$282,320 		100,000 +666.7% 2.82 US$282,320
2018-08-21 2018-08-17 PP Planned purchase RODRIGUEZ RAUL R

CEO, President

Executive Director
114,000 +191.5%
2.63
US$300,002 		114,000 +191.5% 2.63 US$300,002
2018-07-05 2018-07-02 PlS Planned sale Duliege Anne-Marie

EVP & Chief Medical Officer

Officer
5,000 -100.0%
2.79
US$13,932 		5,000 -100.0% 2.79 US$13,932
2018-04-24 2018-04-20 PlS Planned sale Duliege Anne-Marie

EVP & Chief Medical Officer
5,000 -100.0%
4.11
US$20,550 		5,000 -100.0% 4.11 US$20,550
2017-11-07 2017-11-03 PlS Planned sale Maynard Ryan D

EVP & CFO
100,000 -100.0%
3.90
US$390,000 		100,000 -100.0% 3.90 US$390,000
2017-07-07 2017-07-05 PlS Planned sale Duliege Anne-Marie

Chief Medical Officer

Officer
5,000 -100.0%
2.69
US$13,427 		5,000 -100.0% 2.69 US$13,427
2017-01-13 2017-01-03 PlS Planned sale Duliege Anne-Marie

Chief Medical Officer

Officer
5,000 -100.0%
2.41
US$12,028 		5,000 -100.0% 2.41 US$12,028
2016-09-01 2016-08-30 PlS Planned sale PAYAN DONALD G

EVP, Pres. Discovery&Research

Executive Director
5,303 -9.1%
4.00
US$21,214 		5,303 -9.1% 4.00 US$21,214
2015-06-12 2015-06-10 S Sale PAYAN DONALD G

EVP, Pres. Discovery&Research

Executive Director
41,666 -41.7%
3.68
US$153,214 		41,666 -41.7% 3.68 US$153,214
2015-04-03 2015-04-01 S Sale PAYAN DONALD G

EVP, Pres. Discovery&Research

Executive Director
10,000 -14.6%
3.75
US$37,518 		10,000 -14.6% 3.75 US$37,518
2014-09-05 2014-09-03 S Sale PAYAN DONALD G

EVP, Pres. Discovery&Research

Executive Director
20,000 -22.6%
2.56
US$51,200 		20,000 -22.6% 2.56 US$51,200
2014-02-26 2014-02-24 S Sale PAYAN DONALD G

EVP, Pres. Discovery&Research

Executive Director
20,000 -18.5%
3.71
US$74,238 		20,000 -18.5% 3.71 US$74,238
2013-11-20 2013-11-19 S Sale BVF PARTNERS L P/IL

See Explanation of Responses

Large shareholder
153,056 -19.1%
2.64
US$404,343 		153,056 -19.1% 2.64 US$404,343
2013-11-20 2013-11-19 S Sale BVF PARTNERS L P/IL

See Explanation of Responses

Large shareholder
331,566 -22.8%
2.64
US$875,931 		331,566 -22.8% 2.64 US$875,931
2013-06-11 2013-06-07 B Purchase BVF PARTNERS L P/IL

See Explanation of Responses

Large shareholder
8,102 +1.0%
3.47
US$28,095 		8,102 +1.0% 3.47 US$28,095
2013-06-11 2013-06-07 B Purchase BVF PARTNERS L P/IL

See Explanation of Responses

Large shareholder
24,598 +1.7%
3.47
US$85,298 		24,598 +1.7% 3.47 US$85,298
2012-09-14 2012-09-13 S Sale VANCE DOLLY

EVP Corp. Affairs, G.C., Sect.

Officer
4,151 -79.0%
10.43
US$43,284 		4,151 -79.0% 10.43 US$43,284
2012-09-11 2012-09-10 S Sale Maynard Ryan D

EVP & CFO

Officer
17,586 -100.0%
10.52
US$184,927 		17,586 -100.0% 10.52 US$184,927
2012-09-14 2012-09-07 S Sale Maynard Ryan D

EVP & CFO

Officer
23,302 -100.0%
10.67
US$248,560 		23,302 -100.0% 10.67 US$248,560
2012-09-11 2012-09-07 S Sale Maynard Ryan D

EVP & CFO

Officer
34,112 -100.0%
10.55
US$359,960 		34,112 -100.0% 10.55 US$359,960
2012-08-09 2012-08-07 S Sale Maynard Ryan D

EVP & CFO

Officer
300 -100.0%
10.63
US$3,188 		300 -100.0% 10.63 US$3,188
2012-08-09 2012-08-07 S Sale Maynard Ryan D

EVP & CFO

Officer
600 -66.7%
10.62
US$6,372 		600 -66.7% 10.62 US$6,372
2012-08-09 2012-08-07 S Sale Maynard Ryan D

EVP & CFO

Officer
100 -10.0%
10.61
US$1,061 		100 -10.0% 10.61 US$1,061
2012-08-09 2012-08-07 S Sale Maynard Ryan D

EVP & CFO

Officer
700 -41.2%
10.60
US$7,420 		700 -41.2% 10.60 US$7,420
2012-06-20 2012-06-19 S Sale PAYAN DONALD G

EVP, Pres. Discovery&Research

Executive Director
100 -0.1%
8.71
US$871 		100 -0.1% 8.71 US$871
2012-06-20 2012-06-19 S Sale PAYAN DONALD G

EVP, Pres. Discovery&Research

Executive Director
9,700 -8.2%
8.70
US$84,390 		9,700 -8.2% 8.70 US$84,390
2012-06-20 2012-06-19 S Sale PAYAN DONALD G

EVP, Pres. Discovery&Research

Executive Director
100 -0.1%
8.72
US$872 		100 -0.1% 8.72 US$872
2012-06-20 2012-06-19 S Sale PAYAN DONALD G

EVP, Pres. Discovery&Research

Executive Director
100 -0.1%
8.75
US$875 		100 -0.1% 8.75 US$875
2011-06-07 2011-05-26 B Purchase Flynn James E Large shareholder
301,424 +10.4%
8.00
US$2,411,392 		301,424 +10.4% 8.00 US$2,411,392
2011-06-07 2011-05-26 B Purchase Flynn James E Large shareholder
229,252 +11.2%
8.00
US$1,834,016 		229,252 +11.2% 8.00 US$1,834,016
2011-06-07 2011-05-26 B Purchase Flynn James E Large shareholder
72,800 +10.6%
8.00
US$582,400 		72,800 +10.6% 8.00 US$582,400
2011-06-07 2011-05-26 B Purchase Flynn James E Large shareholder
46,524 +11.0%
8.00
US$372,192 		46,524 +11.0% 8.00 US$372,192
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