|
2026-06-24 |
2026-06-22 |
Por favor
Venta prevista
|
Consejero no ejecutivo
|
92 486
-25.3%
59,05
1.041.116 US$
|
92 486
-25.3%
|
59,05
|
1.041.116 US$
|
|
|
2026-06-22 |
2026-06-22 |
PrS
Venta propuesta
|
Director
Consejero no ejecutivo
|
79 403
218,19
2.167.933 US$
|
79 403
|
218,19
|
2.167.933 US$
|
|
|
2026-06-22 |
2026-06-22 |
PrS
Venta propuesta
|
Director
Consejero no ejecutivo
|
93 815
177,27
2.313.490 US$
|
93 815
|
177,27
|
2.313.490 US$
|
|
|
2026-05-28 |
2026-05-26 |
Por favor
Venta prevista
|
Consejero no ejecutivo
|
2 500
-16.5%
29,17
72.925 US$
|
2 500
-16.5%
|
29,17
|
72.925 US$
|
|
|
2026-05-26 |
2026-05-26 |
PrS
Venta propuesta
|
Director
Consejero no ejecutivo
|
2 500
29,17
72.925 US$
|
2 500
|
29,17
|
72.925 US$
|
|
|
2026-02-24 |
2026-02-20 |
S
Venta
|
Consejero no ejecutivo
|
4 000
-23.9%
36,36
145.440 US$
|
4 000
-23.9%
|
36,36
|
145.440 US$
|
|
|
2026-02-20 |
2026-02-20 |
PrS
Venta propuesta
|
Director
Consejero no ejecutivo
|
4 000
36,36
145.440 US$
|
4 000
|
36,36
|
145.440 US$
|
|
|
2025-02-06 |
2025-02-05 |
S
Venta
|
EVP, Chief Commercial Officer
Oficial
|
1 796
-3.4%
21,93
39.379 US$
|
1 796
-3.4%
|
21,93
|
39.379 US$
|
|
|
2025-02-06 |
2025-02-05 |
S
Venta
|
EVP, GC, CCO & Corp Sec
Oficial
|
1 339
-3.3%
21,93
29.359 US$
|
1 339
-3.3%
|
21,93
|
29.359 US$
|
|
|
2025-02-06 |
2025-02-05 |
S
Venta
|
CEO, President
Consejero ejecutivo
|
4 400
-1.8%
21,93
96.474 US$
|
4 400
-1.8%
|
21,93
|
96.474 US$
|
|
|
2025-02-06 |
2025-02-05 |
S
Venta
|
EVP & Chief Financial Officer
Oficial
|
1 734
-2.9%
21,93
38.020 US$
|
1 734
-2.9%
|
21,93
|
38.020 US$
|
|
|
2025-02-05 |
2025-02-05 |
PrS
Venta propuesta
|
Officer
Oficial
|
1 796
21,93
39.379 US$
|
1 796
|
21,93
|
39.379 US$
|
|
|
2025-02-05 |
2025-02-05 |
PrS
Venta propuesta
|
Officer
Oficial
|
1 734
21,93
38.020 US$
|
1 734
|
21,93
|
38.020 US$
|
|
|
2025-02-05 |
2025-02-05 |
PrS
Venta propuesta
|
Officer
Oficial
|
1 339
21,93
29.359 US$
|
1 339
|
21,93
|
29.359 US$
|
|
|
2025-02-05 |
2025-02-05 |
PrS
Venta propuesta
|
Officer; Director
Consejero ejecutivo
|
4 400
21,93
96.474 US$
|
4 400
|
21,93
|
96.474 US$
|
|
|
2025-02-06 |
2025-02-04 |
S
Venta
|
EVP, Chief Commercial Officer
Oficial
|
2 125
-3.8%
20,92
44.457 US$
|
2 125
-3.8%
|
20,92
|
44.457 US$
|
|
|
2025-02-06 |
2025-02-04 |
S
Venta
|
EVP, GC, CCO & Corp Sec
Oficial
|
1 448
-3.5%
20,92
30.294 US$
|
1 448
-3.5%
|
20,92
|
30.294 US$
|
|
|
2025-02-06 |
2025-02-04 |
S
Venta
|
CEO, President
Consejero ejecutivo
|
4 952
-2.0%
20,92
103.601 US$
|
4 952
-2.0%
|
20,92
|
103.601 US$
|
|
|
2025-02-06 |
2025-02-04 |
S
Venta
|
EVP & Chief Financial Officer
Oficial
|
2 036
-3.3%
20,92
42.595 US$
|
2 036
-3.3%
|
20,92
|
42.595 US$
|
|
|
2025-02-04 |
2025-02-04 |
PrS
Venta propuesta
|
Officer
Oficial
|
2 036
20,92
42.596 US$
|
2 036
|
20,92
|
42.596 US$
|
|
|
2025-02-04 |
2025-02-04 |
PrS
Venta propuesta
|
Officer; Director
Consejero ejecutivo
|
4 952
20,92
103.602 US$
|
4 952
|
20,92
|
103.602 US$
|
|
|
2025-02-04 |
2025-02-04 |
PrS
Venta propuesta
|
Officer
Oficial
|
1 448
20,92
30.294 US$
|
1 448
|
20,92
|
30.294 US$
|
|
|
2025-02-04 |
2025-02-04 |
PrS
Venta propuesta
|
Officer
Oficial
|
2 125
20,92
44.458 US$
|
2 125
|
20,92
|
44.458 US$
|
|
|
2025-01-24 |
2025-01-24 |
PrS
Venta propuesta
|
Officer
Oficial
|
4 999
22,14
110.678 US$
|
4 999
|
22,14
|
110.678 US$
|
|
|
2024-02-06 |
2024-02-05 |
S
Venta
|
CEO, President
Consejero ejecutivo
|
30 545
-1.5%
1,14
34.821 US$
|
30 545
-1.5%
|
1,14
|
34.821 US$
|
|
|
2024-02-06 |
2024-02-05 |
S
Venta
|
EVP & Chief Financial Officer
Oficial
|
7 027
-1.7%
1,14
8.011 US$
|
7 027
-1.7%
|
1,14
|
8.011 US$
|
|
|
2024-02-06 |
2024-02-05 |
S
Venta
|
EVP, Chief Commercial Officer
Oficial
|
8 918
-2.5%
1,14
10.167 US$
|
8 918
-2.5%
|
1,14
|
10.167 US$
|
|
|
2024-02-06 |
2024-02-02 |
S
Venta
|
CEO, President
Consejero ejecutivo
|
22 349
-1.1%
1,13
25.261 US$
|
22 349
-1.1%
|
1,13
|
25.261 US$
|
|
|
2024-02-06 |
2024-02-02 |
S
Venta
|
EVP & Chief Financial Officer
Oficial
|
5 601
-1.3%
1,13
6.327 US$
|
5 601
-1.3%
|
1,13
|
6.327 US$
|
|
|
2024-02-06 |
2024-02-02 |
S
Venta
|
EVP, Chief Commercial Officer
Oficial
|
5 601
-1.5%
1,13
6.329 US$
|
5 601
-1.5%
|
1,13
|
6.329 US$
|
|
|
2023-02-07 |
2023-02-06 |
S
Venta
|
CEO, President
Consejero ejecutivo
|
20 340
-1.2%
1,75
35.595 US$
|
20 340
-1.2%
|
1,75
|
35.595 US$
|
|
|
2023-02-06 |
2023-02-02 |
S
Venta
|
EVP & Chief Financial Officer
Oficial
|
5 389
-2.7%
1,66
8.946 US$
|
5 389
-2.7%
|
1,66
|
8.946 US$
|
|
|
2023-02-06 |
2023-02-02 |
S
Venta
|
EVP, Chief Commercial Officer
Oficial
|
5 388
-3.6%
1,66
8.945 US$
|
5 388
-3.6%
|
1,66
|
8.945 US$
|
|
|
2023-02-06 |
2023-02-02 |
S
Venta
|
EVP & CMO
Oficial
|
5 389
-6.9%
1,66
8.946 US$
|
5 389
-6.9%
|
1,66
|
8.946 US$
|
|
|
2022-06-13 |
2022-06-09 |
B
Compra
|
CEO, President
Consejero ejecutivo
|
1 000 000
+255.2%
0,69
688.400 US$
|
1 000 000
+255.2%
|
0,69
|
688.400 US$
|
|
|
2019-05-23 |
2019-05-22 |
B
Compra
|
EVP &Chief Financial Officer
Oficial
|
3 274
+7.0%
2,13
6.971 US$
|
3 274
+7.0%
|
2,13
|
6.971 US$
|
|
|
2019-05-23 |
2019-05-22 |
B
Compra
|
EVP &Chief Financial Officer
Oficial
|
46 726
+inf%
2,13
99.573 US$
|
46 726
+inf%
|
2,13
|
99.573 US$
|
|
|
2018-10-16 |
2018-10-12 |
Por favor
Venta prevista
|
Cabatuan Nelson
Principal Accounting Officer
Oficial
|
10 000
-99.4%
3,12
31.200 US$
|
10 000
-99.4%
|
3,12
|
31.200 US$
|
|
|
2018-09-19 |
2018-09-17 |
Por favor
Venta prevista
|
Duliege Anne-Marie
EVP & Chief Medical Officer
Oficial
|
37 500
-100.0%
3,50
131.250 US$
|
37 500
-100.0%
|
3,50
|
131.250 US$
|
|
|
2018-09-19 |
2018-09-17 |
Por favor
Venta prevista
|
Duliege Anne-Marie
EVP & Chief Medical Officer
Oficial
|
115 500
-100.0%
3,50
404.250 US$
|
115 500
-100.0%
|
3,50
|
404.250 US$
|
|
|
2018-09-12 |
2018-09-11 |
B
Compra
|
Mayer Eldon C. III
EVP & Chief Commercial Officer
Oficial
|
50 000
+30.3%
3,23
161.340 US$
|
50 000
+30.3%
|
3,23
|
161.340 US$
|
|
|
2018-09-12 |
2018-09-10 |
B
Compra
|
Mayer Eldon C. III
EVP & Chief Commercial Officer
Oficial
|
50 000
+43.5%
3,28
164.210 US$
|
50 000
+43.5%
|
3,28
|
164.210 US$
|
|
|
2018-09-06 |
2018-09-04 |
Por favor
Venta prevista
|
Duliege Anne-Marie
EVP & Chief Medical Officer
Oficial
|
16 500
-100.0%
3,51
57.861 US$
|
16 500
-100.0%
|
3,51
|
57.861 US$
|
|
|
2018-08-27 |
2018-08-23 |
PÁGINAS
Compra planificada
|
Mayer Eldon C. III
EVP & Chief Commercial Officer
Oficial
|
100 000
+666.7%
2,82
282.320 US$
|
100 000
+666.7%
|
2,82
|
282.320 US$
|
|
|
2018-08-21 |
2018-08-17 |
PÁGINAS
Compra planificada
|
RODRIGUEZ RAUL R
CEO, President
Consejero ejecutivo
|
114 000
+191.5%
2,63
300.002 US$
|
114 000
+191.5%
|
2,63
|
300.002 US$
|
|
|
2018-07-05 |
2018-07-02 |
Por favor
Venta prevista
|
Duliege Anne-Marie
EVP & Chief Medical Officer
Oficial
|
5 000
-100.0%
2,79
13.932 US$
|
5 000
-100.0%
|
2,79
|
13.932 US$
|
|
|
2018-04-24 |
2018-04-20 |
Por favor
Venta prevista
|
Duliege Anne-Marie
EVP & Chief Medical Officer
|
5 000
-100.0%
4,11
20.550 US$
|
5 000
-100.0%
|
4,11
|
20.550 US$
|
|
|
2017-11-07 |
2017-11-03 |
Por favor
Venta prevista
|
Maynard Ryan D
EVP & CFO
|
100 000
-100.0%
3,90
390.000 US$
|
100 000
-100.0%
|
3,90
|
390.000 US$
|
|
|
2017-07-07 |
2017-07-05 |
Por favor
Venta prevista
|
Duliege Anne-Marie
Chief Medical Officer
Oficial
|
5 000
-100.0%
2,69
13.427 US$
|
5 000
-100.0%
|
2,69
|
13.427 US$
|
|
|
2017-01-13 |
2017-01-03 |
Por favor
Venta prevista
|
Duliege Anne-Marie
Chief Medical Officer
Oficial
|
5 000
-100.0%
2,41
12.028 US$
|
5 000
-100.0%
|
2,41
|
12.028 US$
|
|
|
2016-09-01 |
2016-08-30 |
Por favor
Venta prevista
|
PAYAN DONALD G
EVP, Pres. Discovery&Research
Consejero ejecutivo
|
5 303
-9.1%
4,00
21.214 US$
|
5 303
-9.1%
|
4,00
|
21.214 US$
|
|
|
2015-06-12 |
2015-06-10 |
S
Venta
|
PAYAN DONALD G
EVP, Pres. Discovery&Research
Consejero ejecutivo
|
41 666
-41.7%
3,68
153.214 US$
|
41 666
-41.7%
|
3,68
|
153.214 US$
|
|
|
2015-04-03 |
2015-04-01 |
S
Venta
|
PAYAN DONALD G
EVP, Pres. Discovery&Research
Consejero ejecutivo
|
10 000
-14.6%
3,75
37.518 US$
|
10 000
-14.6%
|
3,75
|
37.518 US$
|
|
|
2014-09-05 |
2014-09-03 |
S
Venta
|
PAYAN DONALD G
EVP, Pres. Discovery&Research
Consejero ejecutivo
|
20 000
-22.6%
2,56
51.200 US$
|
20 000
-22.6%
|
2,56
|
51.200 US$
|
|
|
2014-02-26 |
2014-02-24 |
S
Venta
|
PAYAN DONALD G
EVP, Pres. Discovery&Research
Consejero ejecutivo
|
20 000
-18.5%
3,71
74.238 US$
|
20 000
-18.5%
|
3,71
|
74.238 US$
|
|
|
2013-11-20 |
2013-11-19 |
S
Venta
|
BVF PARTNERS L P/IL
See Explanation of Responses
Gran accionista
|
153 056
-19.1%
2,64
404.343 US$
|
153 056
-19.1%
|
2,64
|
404.343 US$
|
|
|
2013-11-20 |
2013-11-19 |
S
Venta
|
BVF PARTNERS L P/IL
See Explanation of Responses
Gran accionista
|
331 566
-22.8%
2,64
875.931 US$
|
331 566
-22.8%
|
2,64
|
875.931 US$
|
|
|
2013-06-11 |
2013-06-07 |
B
Compra
|
BVF PARTNERS L P/IL
See Explanation of Responses
Gran accionista
|
8 102
+1.0%
3,47
28.095 US$
|
8 102
+1.0%
|
3,47
|
28.095 US$
|
|
|
2013-06-11 |
2013-06-07 |
B
Compra
|
BVF PARTNERS L P/IL
See Explanation of Responses
Gran accionista
|
24 598
+1.7%
3,47
85.298 US$
|
24 598
+1.7%
|
3,47
|
85.298 US$
|
|
|
2012-09-14 |
2012-09-13 |
S
Venta
|
VANCE DOLLY
EVP Corp. Affairs, G.C., Sect.
Oficial
|
4 151
-79.0%
10,43
43.284 US$
|
4 151
-79.0%
|
10,43
|
43.284 US$
|
|
|
2012-09-11 |
2012-09-10 |
S
Venta
|
Maynard Ryan D
EVP & CFO
Oficial
|
17 586
-100.0%
10,52
184.927 US$
|
17 586
-100.0%
|
10,52
|
184.927 US$
|
|
|
2012-09-14 |
2012-09-07 |
S
Venta
|
Maynard Ryan D
EVP & CFO
Oficial
|
23 302
-100.0%
10,67
248.560 US$
|
23 302
-100.0%
|
10,67
|
248.560 US$
|
|
|
2012-09-11 |
2012-09-07 |
S
Venta
|
Maynard Ryan D
EVP & CFO
Oficial
|
34 112
-100.0%
10,55
359.960 US$
|
34 112
-100.0%
|
10,55
|
359.960 US$
|
|
|
2012-08-09 |
2012-08-07 |
S
Venta
|
Maynard Ryan D
EVP & CFO
Oficial
|
300
-100.0%
10,63
3.188 US$
|
300
-100.0%
|
10,63
|
3.188 US$
|
|
|
2012-08-09 |
2012-08-07 |
S
Venta
|
Maynard Ryan D
EVP & CFO
Oficial
|
600
-66.7%
10,62
6.372 US$
|
600
-66.7%
|
10,62
|
6.372 US$
|
|
|
2012-08-09 |
2012-08-07 |
S
Venta
|
Maynard Ryan D
EVP & CFO
Oficial
|
100
-10.0%
10,61
1.061 US$
|
100
-10.0%
|
10,61
|
1.061 US$
|
|
|
2012-08-09 |
2012-08-07 |
S
Venta
|
Maynard Ryan D
EVP & CFO
Oficial
|
700
-41.2%
10,60
7.420 US$
|
700
-41.2%
|
10,60
|
7.420 US$
|
|
|
2012-06-20 |
2012-06-19 |
S
Venta
|
PAYAN DONALD G
EVP, Pres. Discovery&Research
Consejero ejecutivo
|
100
-0.1%
8,71
871 US$
|
100
-0.1%
|
8,71
|
871 US$
|
|
|
2012-06-20 |
2012-06-19 |
S
Venta
|
PAYAN DONALD G
EVP, Pres. Discovery&Research
Consejero ejecutivo
|
9 700
-8.2%
8,70
84.390 US$
|
9 700
-8.2%
|
8,70
|
84.390 US$
|
|
|
2012-06-20 |
2012-06-19 |
S
Venta
|
PAYAN DONALD G
EVP, Pres. Discovery&Research
Consejero ejecutivo
|
100
-0.1%
8,72
872 US$
|
100
-0.1%
|
8,72
|
872 US$
|
|
|
2012-06-20 |
2012-06-19 |
S
Venta
|
PAYAN DONALD G
EVP, Pres. Discovery&Research
Consejero ejecutivo
|
100
-0.1%
8,75
875 US$
|
100
-0.1%
|
8,75
|
875 US$
|
|
|
2011-06-07 |
2011-05-26 |
B
Compra
|
Flynn James E
Gran accionista
|
301 424
+10.4%
8,00
2.411.392 US$
|
301 424
+10.4%
|
8,00
|
2.411.392 US$
|
|
|
2011-06-07 |
2011-05-26 |
B
Compra
|
Flynn James E
Gran accionista
|
229 252
+11.2%
8,00
1.834.016 US$
|
229 252
+11.2%
|
8,00
|
1.834.016 US$
|
|
|
2011-06-07 |
2011-05-26 |
B
Compra
|
Flynn James E
Gran accionista
|
72 800
+10.6%
8,00
582.400 US$
|
72 800
+10.6%
|
8,00
|
582.400 US$
|
|
|
2011-06-07 |
2011-05-26 |
B
Compra
|
Flynn James E
Gran accionista
|
46 524
+11.0%
8,00
372.192 US$
|
46 524
+11.0%
|
8,00
|
372.192 US$
|
|