30% off. Use code SUMMERSALE30 at checkout for 30% off for 12 months on Plus, Pro and Premium subscriptions. Subscribe now
United States Biotechnology & Medical Research

Prime Medicine Inc (PRME)

Track

The most recent insider trading activity occurred on August 1, 2025, with significant buy transactions totaling over $30 million from entities including NELSEN ROBERT and ARCH Venture Partners. Earlier in 2025, there were several smaller buy transactions by executives and planned purchases. The last reported transaction prior to August 2025 was a planned sale in June 2025.
Stock chart
Ticker: PRME Exchange: NMS
Preparing chart...
Download chart Copy chart image Copy link Share to X Share


Subscribe to get access to the transaction volume chart and in-chart transaction details
• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
GV 2021 GP, L.L.C.
1 purchase — total 4,950,000 USD
Buy 1 Aug 2025
Value US$3,533,428.05 | Price 343.82 | Shares 60,175
Buy 1 Aug 2025
Value US$168,380.73 | Price 229.54 | Shares 6,658
Buy 1 Aug 2025
Value US$9,999,990.00 | Price 3.30 | Shares 3,030,300
Buy 1 Aug 2025
Value US$9,999,990.00 | Price 3.30 | Shares 3,030,300
Planned buy 30 Jun 2025
Value US$52,829.70 | Price 2.52 | Shares 21,000
Planned buy 23 Jun 2025
Value US$45,402.00 | Price 2.16 | Shares 21,000
Planned buy 16 Jun 2025
Value US$31,195.50 | Price 1.49 | Shares 21,000
Planned buy 11 Jun 2025
Value US$33,589.50 | Price 1.60 | Shares 21,000
Buy 21 May 2025
Value US$113,000.00 | Price 1.13 | Shares 100,000
Buy 21 May 2025
Value US$147,150.00 | Price 1.18 | Shares 125,000
Buy 20 May 2025
Value US$23,790.00 | Price 1.19 | Shares 20,000
Buy 15 Feb 2024
Value US$20,000,000.00 | Price 6.25 | Shares 3,200,000
Buy 15 Feb 2024
Value US$20,000,000.00 | Price 6.25 | Shares 3,200,000
Buy 15 Feb 2024
Value US$20,000,000.00 | Price 6.25 | Shares 3,200,000
Planned sale 21 Jun 2023
Value US$284,495.81 | Price 14.97 | Shares 19,003
Planned sale 20 Jun 2023
Value US$563,248.23 | Price 15.06 | Shares 37,405
Proposed sale 20 Jun 2023
Value US$7,791,384.51 | Price 14.91 | Shares 522,561
Planned sale 16 Jun 2023
Value US$98,109.33 | Price 15.02 | Shares 6,532
Planned sale 15 Jun 2023
Value US$994,325.64 | Price 14.92 | Shares 66,659
Planned sale 14 Jun 2023
Value US$430,684.43 | Price 14.87 | Shares 28,960
Planned sale 13 Jun 2023
Value US$425,102.42 | Price 15.13 | Shares 28,100
Planned sale 12 Jun 2023
Value US$240,150.79 | Price 14.98 | Shares 16,031
Proposed sale 12 Jun 2023
Value US$2,312,542.42 | Price 14.49 | Shares 159,596
Planned sale 9 Jun 2023
Value US$226,983.84 | Price 14.48 | Shares 15,672
Planned sale 8 Jun 2023
Value US$78,686.50 | Price 15.74 | Shares 5,000
Planned sale 7 Jun 2023
Value US$253,870.50 | Price 16.92 | Shares 15,000
Planned sale 6 Jun 2023
Value US$510,165.51 | Price 17.02 | Shares 29,975
Planned sale 5 Jun 2023
Value US$374,611.91 | Price 16.70 | Shares 22,434
Proposed sale 5 Jun 2023
Value US$1,418,984.91 | Price 16.11 | Shares 88,081
Planned sale 1 Jun 2023
Value US$6,948.85 | Price 14.75 | Shares 471
Planned sale 1 Jun 2023
Value US$642,244.90 | Price 14.35 | Shares 44,752
Planned sale 31 May 2023
Value US$227,003.86 | Price 13.65 | Shares 16,633
Planned sale 30 May 2023
Value US$230,240.26 | Price 13.70 | Shares 16,805
Proposed sale 30 May 2023
Value US$974,165.21 | Price 13.67 | Shares 71,263
Planned sale 26 May 2023
Value US$172,603.29 | Price 13.70 | Shares 12,602
Planned sale 25 May 2023
Value US$309,972.93 | Price 13.38 | Shares 23,161
Planned sale 24 May 2023
Value US$107,920.32 | Price 13.66 | Shares 7,900
Planned sale 23 May 2023
Value US$647,647.68 | Price 14.74 | Shares 43,939
Planned sale 22 May 2023
Value US$1,242,091.68 | Price 14.13 | Shares 87,922
Planned sale 19 May 2023
Value US$877,066.50 | Price 13.88 | Shares 63,212
Planned sale 18 May 2023
Value US$183,170.79 | Price 13.06 | Shares 14,022
Planned sale 18 May 2023
Value US$170,100.45 | Price 13.01 | Shares 13,076
Proposed sale 18 May 2023
Value US$3,387,231.12 | Price 13.02 | Shares 260,156
Planned sale 17 May 2023
Value US$191,599.50 | Price 12.77 | Shares 15,000
Planned sale 16 May 2023
Value US$637,675.97 | Price 12.59 | Shares 50,649
Planned sale 15 May 2023
Value US$2,012,087.35 | Price 12.74 | Shares 157,952
Planned sale 12 May 2023
Value US$347,221.59 | Price 12.72 | Shares 27,290
Planned sale 11 May 2023
Value US$66,289.97 | Price 13.79 | Shares 4,807
Planned sale 11 May 2023
Value US$283,243.35 | Price 12.98 | Shares 21,819
Planned sale 10 May 2023
Value US$1,225,804.10 | Price 14.03 | Shares 87,397
Planned sale 9 May 2023
Value US$4,522,613.43 | Price 14.08 | Shares 321,238
Planned sale 8 May 2023
Value US$1,423,726.97 | Price 14.13 | Shares 100,772
Proposed sale 8 May 2023
Value US$16,055,541.00 | Price 14.32 | Shares 1,121,197
Buy 24 Oct 2022
Value US$6,800,000.00 | Price 17.00 | Shares 400,000
Buy 24 Oct 2022
Value US$6,800,000.00 | Price 17.00 | Shares 400,000
Buy 24 Oct 2022
Value US$6,800,000.00 | Price 17.00 | Shares 400,000
Buy 24 Oct 2022
Value US$6,800,000.00 | Price 17.00 | Shares 400,000
Buy 24 Oct 2022
Value US$6,800,000.00 | Price 17.00 | Shares 400,000
Buy 24 Oct 2022
Value US$13,600,000.00 | Price 17.00 | Shares 800,000
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2025-08-05 2025-08-01 B Purchase
4.3
GV 2021 GP, L.L.C.
Large shareholder
60,175 +11.0%
343.82
US$3,533,428 		60,175 +11.0% 343.82 US$3,533,428
2025-08-01 2025-08-01 B Purchase
3.3
NELSEN ROBERT
Non-Executive Director Large shareholder
6,658 +29.4%
229.54
US$168,381 		6,658 +29.4% 229.54 US$168,381
2025-08-01 2025-08-01 B Purchase
3.6
ARCH Venture Partners XII, LLC
Large shareholder
65,787 -23.2%
313.46
US$512,085 		65,787 -23.2% 313.46 US$512,085
2025-08-01 2025-08-01 B Purchase
3.4
ARCH Venture Partners X, LLC
Large shareholder
3,030,300 +94.7%
3.30
US$9,999,990 		3,030,300 +94.7% 3.30 US$9,999,990
2025-07-01 2025-06-30 PP Planned purchase
Liu David R.
Large shareholder
21,000 +0.1%
2.52
US$52,830 		21,000 +0.1% 2.52 US$52,830
2025-06-23 2025-06-23 PP Planned purchase
Liu David R.
Large shareholder
21,000 +0.1%
2.16
US$45,402 		21,000 +0.1% 2.16 US$45,402
2025-06-16 2025-06-16 PP Planned purchase
Liu David R.
Large shareholder
21,000 +0.1%
1.49
US$31,196 		21,000 +0.1% 1.49 US$31,196
2025-06-12 2025-06-11 PP Planned purchase
Liu David R.
Large shareholder
21,000 +0.1%
1.60
US$33,590 		21,000 +0.1% 1.60 US$33,590
2025-05-22 2025-05-21 B Purchase
3.4
LEE ANN L.

Chief Technical Officer

Officer
100,000 +inf%
1.13
US$113,000 		100,000 +inf% 1.13 US$113,000
2025-05-22 2025-05-21 B Purchase
3.4
Reine Allan

Chief Executive Officer

Executive Director
125,000 +inf%
1.18
US$147,150 		125,000 +inf% 1.18 US$147,150
2025-05-22 2025-05-20 B Purchase
3.4
Brudnick Richard

Chief Business Officer

Officer
20,000 +inf%
1.19
US$23,790 		20,000 +inf% 1.19 US$23,790
2024-02-20 2024-02-15 B Purchase
3.3
NELSEN ROBERT
Non-Executive Director Large shareholder
3,200,000 +inf%
6.25
US$20,000,000 		3,200,000 +inf% 6.25 US$20,000,000
2024-02-20 2024-02-15 B Purchase
3.4
ARCH Venture Partners X, LLC
Large shareholder
3,200,000 +inf%
6.25
US$20,000,000 		3,200,000 +inf% 6.25 US$20,000,000
2024-02-20 2024-02-15 B Purchase
3.6
ARCH Venture Partners XII, LLC
Large shareholder
3,200,000 +inf%
6.25
US$20,000,000 		3,200,000 +inf% 6.25 US$20,000,000
2023-06-22 2023-06-21 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
19,003 -100.0%
14.97
US$284,496 		19,003 -100.0% 14.97 US$284,496
2023-06-22 2023-06-20 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
37,405 -100.0%
15.06
US$563,248 		37,405 -100.0% 15.06 US$563,248
2023-06-20 2023-06-20 PrS Proposed sale
Alphabet Holdings LLC

10% Stockholder

Large shareholder
522,561
14.91
US$7,791,385 		522,561 14.91 US$7,791,385
2023-06-20 2023-06-16 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
6,532 -100.0%
15.02
US$98,109 		6,532 -100.0% 15.02 US$98,109
2023-06-20 2023-06-15 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
66,659 -100.0%
14.92
US$994,326 		66,659 -100.0% 14.92 US$994,326
2023-06-15 2023-06-14 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
28,960 -100.0%
14.87
US$430,684 		28,960 -100.0% 14.87 US$430,684
2023-06-15 2023-06-13 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
28,100 -100.0%
15.13
US$425,102 		28,100 -100.0% 15.13 US$425,102
2023-06-13 2023-06-12 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
16,031 -100.0%
14.98
US$240,151 		16,031 -100.0% 14.98 US$240,151
2023-06-12 2023-06-12 PrS Proposed sale
Alphabet Holdings LLC

10% Stockholder

Large shareholder
159,596
14.49
US$2,312,542 		159,596 14.49 US$2,312,542
2023-06-13 2023-06-09 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
15,672 -100.0%
14.48
US$226,984 		15,672 -100.0% 14.48 US$226,984
2023-06-09 2023-06-08 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
5,000 -100.0%
15.74
US$78,686 		5,000 -100.0% 15.74 US$78,686
2023-06-09 2023-06-07 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
15,000 -100.0%
16.92
US$253,870 		15,000 -100.0% 16.92 US$253,870
2023-06-07 2023-06-06 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
29,975 -100.0%
17.02
US$510,166 		29,975 -100.0% 17.02 US$510,166
2023-06-07 2023-06-05 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
22,434 -100.0%
16.70
US$374,612 		22,434 -100.0% 16.70 US$374,612
2023-06-05 2023-06-05 PrS Proposed sale
Alphabet Holdings LLC

10% Stockholder

Large shareholder
88,081
16.11
US$1,418,985 		88,081 16.11 US$1,418,985
2023-06-02 2023-06-01 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
471 -100.0%
14.75
US$6,949 		471 -100.0% 14.75 US$6,949
2023-06-02 2023-06-01 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
44,752 -99.0%
14.35
US$642,245 		44,752 -99.0% 14.35 US$642,245
2023-06-02 2023-05-31 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
16,633 -100.0%
13.65
US$227,004 		16,633 -100.0% 13.65 US$227,004
2023-05-31 2023-05-30 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
16,805 -100.0%
13.70
US$230,240 		16,805 -100.0% 13.70 US$230,240
2023-05-30 2023-05-30 PrS Proposed sale
Alphabet Holdings LLC

10% Stockholder

Large shareholder
71,263
13.67
US$974,165 		71,263 13.67 US$974,165
2023-05-31 2023-05-26 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
12,602 -100.0%
13.70
US$172,603 		12,602 -100.0% 13.70 US$172,603
2023-05-26 2023-05-25 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
23,161 -100.0%
13.38
US$309,973 		23,161 -100.0% 13.38 US$309,973
2023-05-26 2023-05-24 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
7,900 -100.0%
13.66
US$107,920 		7,900 -100.0% 13.66 US$107,920
2023-05-24 2023-05-23 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
43,939 -100.0%
14.74
US$647,648 		43,939 -100.0% 14.74 US$647,648
2023-05-24 2023-05-22 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
87,922 -100.0%
14.13
US$1,242,092 		87,922 -100.0% 14.13 US$1,242,092
2023-05-22 2023-05-19 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
63,212 -100.0%
13.88
US$877,066 		63,212 -100.0% 13.88 US$877,066
2023-05-22 2023-05-18 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
14,022 -100.0%
13.06
US$183,171 		14,022 -100.0% 13.06 US$183,171
2023-05-22 2023-05-18 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
13,076 -0.1%
13.01
US$170,100 		13,076 -0.1% 13.01 US$170,100
2023-05-18 2023-05-18 PrS Proposed sale
Alphabet Holdings LLC

10% Stockholder

Large shareholder
260,156
13.02
US$3,387,231 		260,156 13.02 US$3,387,231
2023-05-18 2023-05-17 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
15,000 -0.1%
12.77
US$191,600 		15,000 -0.1% 12.77 US$191,600
2023-05-18 2023-05-16 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
50,649 -0.5%
12.59
US$637,676 		50,649 -0.5% 12.59 US$637,676
2023-05-16 2023-05-15 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
157,952 -1.4%
12.74
US$2,012,087 		157,952 -1.4% 12.74 US$2,012,087
2023-05-16 2023-05-12 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
27,290 -0.2%
12.72
US$347,222 		27,290 -0.2% 12.72 US$347,222
2023-05-12 2023-05-11 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
4,807 -0.0%
13.79
US$66,290 		4,807 -0.0% 13.79 US$66,290
2023-05-12 2023-05-11 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
21,819 -0.2%
12.98
US$283,243 		21,819 -0.2% 12.98 US$283,243
2023-05-12 2023-05-10 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
87,397 -0.8%
14.03
US$1,225,804 		87,397 -0.8% 14.03 US$1,225,804
2023-05-10 2023-05-09 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
321,238 -2.8%
14.08
US$4,522,613 		321,238 -2.8% 14.08 US$4,522,613
2023-05-10 2023-05-08 PlS Planned sale
2.4
GV 2019 GP, L.L.C.
Large shareholder
100,772 -0.9%
14.13
US$1,423,727 		100,772 -0.9% 14.13 US$1,423,727
2023-05-08 2023-05-08 PrS Proposed sale
GV 2019, L.P.

10% Stockholder

Large shareholder
1,121,197
14.32
US$16,055,541 		1,121,197 14.32 US$16,055,541
2022-10-26 2022-10-24 B Purchase
3.4
ARCH Venture Partners X, LLC
Large shareholder
400,000 +7.0%
17.00
US$6,800,000 		400,000 +7.0% 17.00 US$6,800,000
2022-10-26 2022-10-24 B Purchase
3.4
ARCH Venture Partners X, LLC
Large shareholder
400,000 +7.0%
17.00
US$6,800,000 		400,000 +7.0% 17.00 US$6,800,000
2022-10-26 2022-10-24 B Purchase
3.3
NELSEN ROBERT
Non-Executive Director Large shareholder
400,000 +7.0%
17.00
US$6,800,000 		400,000 +7.0% 17.00 US$6,800,000
2022-10-26 2022-10-24 B Purchase
3.3
NELSEN ROBERT
Non-Executive Director Large shareholder
400,000 +7.0%
17.00
US$6,800,000 		400,000 +7.0% 17.00 US$6,800,000
2022-10-26 2022-10-24 B Purchase
2.4
Cahill Thomas
Non-Executive Director
400,000 +8.2%
17.00
US$6,800,000 		400,000 +8.2% 17.00 US$6,800,000
2022-10-26 2022-10-24 B Purchase
2.4
GV 2019 GP, L.L.C.
Large shareholder
800,000 +7.5%
17.00
US$13,600,000 		800,000 +7.5% 17.00 US$13,600,000
Explore more

More insider trading research around Prime Medicine Inc

More insider trades in United States
Similar Healthcare companies with insider activity
More Pharmaceuticals & Medical Research companies with insider activity
More Biotechnology & Medical Research companies with insider activity
Insider trading in North America