|
2025-01-17 |
2025-01-15 |
S
Sale
|
Hager Alicia J.
Chief Legal Officer
Officer
|
9,584
-6.1%
2.20
USD 21,085
|
9,584
-6.1%
|
2.20
|
USD 21,085
|
|
|
2025-01-17 |
2025-01-15 |
S
Sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
7,447
-5.6%
2.20
USD 16,383
|
7,447
-5.6%
|
2.20
|
USD 16,383
|
|
|
2025-01-17 |
2025-01-15 |
S
Sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
17,378
-5.2%
2.20
USD 38,232
|
17,378
-5.2%
|
2.20
|
USD 38,232
|
|
|
2025-01-17 |
2025-01-15 |
S
Sale
|
Shook David
See Remarks
Officer
|
8,638
-4.3%
2.20
USD 19,004
|
8,638
-4.3%
|
2.20
|
USD 19,004
|
|
|
2025-01-17 |
2025-01-15 |
S
Sale
|
Levin Alyssa
See Remarks
Officer
|
5,838
-5.4%
2.20
USD 12,844
|
5,838
-5.4%
|
2.20
|
USD 12,844
|
|
|
2024-07-18 |
2024-07-16 |
PS
Planned sale
|
Hager Alicia J.
Chief Legal Officer
Officer
|
3,396
-3.2%
8.00
USD 27,168
|
3,396
-3.2%
|
8.00
|
USD 27,168
|
|
|
2024-06-20 |
2024-06-18 |
S
Sale
|
Shook David
Chief Medical Officer
Officer
|
456
-0.4%
5.60
USD 2,554
|
456
-0.4%
|
5.60
|
USD 2,554
|
|
|
2024-06-20 |
2024-06-18 |
S
Sale
|
Trager James
Chief Scientific Officer
Officer
|
456
-0.3%
5.60
USD 2,554
|
456
-0.3%
|
5.60
|
USD 2,554
|
|
|
2024-06-20 |
2024-06-18 |
S
Sale
|
Hager Alicia J.
Chief Legal Officer
Officer
|
727
-0.7%
5.60
USD 4,071
|
727
-0.7%
|
5.60
|
USD 4,071
|
|
|
2024-06-20 |
2024-06-18 |
S
Sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
1,770
-0.7%
5.60
USD 9,912
|
1,770
-0.7%
|
5.60
|
USD 9,912
|
|
|
2024-06-20 |
2024-06-18 |
S
Sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
229
-0.3%
5.60
USD 1,282
|
229
-0.3%
|
5.60
|
USD 1,282
|
|
|
2024-03-29 |
2024-03-27 |
B
Purchase
|
RA CAPITAL MANAGEMENT, L.P.
Non-Executive Director
Large shareholder
|
3,000,000
+42.5%
10.00
USD 30,000,000
|
3,000,000
+42.5%
|
10.00
|
USD 30,000,000
|
|
|
2024-03-28 |
2024-03-27 |
B
Purchase
|
George Simeon
Non-Executive Director
|
451,659
+inf%
10.00
USD 4,516,590
|
451,659
+inf%
|
10.00
|
USD 4,516,590
|
|
|
2024-03-28 |
2024-03-27 |
B
Purchase
|
George Simeon
Non-Executive Director
|
1,548,341
+inf%
10.00
USD 15,483,410
|
1,548,341
+inf%
|
10.00
|
USD 15,483,410
|
|
|
2024-03-05 |
2024-03-01 |
PS
Planned sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
8,367
-9.5%
12.51
USD 104,671
|
8,367
-9.5%
|
12.51
|
USD 104,671
|
|
|
2024-02-14 |
2024-02-12 |
PS
Planned sale
|
Trager James
Chief Scientific Officer
Officer
|
4,143
-2.7%
12.00
USD 49,716
|
4,143
-2.7%
|
12.00
|
USD 49,716
|
|
|
2024-01-18 |
2024-01-16 |
S
Sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
2,512
-3.0%
8.74
USD 21,955
|
2,512
-3.0%
|
8.74
|
USD 21,955
|
|
|
2024-01-18 |
2024-01-16 |
S
Sale
|
Shook David
Chief Medical Officer
Officer
|
3,552
-3.0%
8.74
USD 31,044
|
3,552
-3.0%
|
8.74
|
USD 31,044
|
|
|
2024-01-18 |
2024-01-16 |
S
Sale
|
Trager James
Chief Scientific Officer
Officer
|
4,560
-2.9%
8.74
USD 39,854
|
4,560
-2.9%
|
8.74
|
USD 39,854
|
|
|
2024-01-18 |
2024-01-16 |
S
Sale
|
Hager Alicia J.
Chief Legal Officer
Officer
|
4,554
-4.0%
8.74
USD 39,802
|
4,554
-4.0%
|
8.74
|
USD 39,802
|
|
|
2024-01-18 |
2024-01-16 |
S
Sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
9,697
-2.4%
8.74
USD 84,752
|
9,697
-2.4%
|
8.74
|
USD 84,752
|
|
|
2023-08-23 |
2023-08-21 |
S
Sale
|
Shook David
Chief Medical Officer
Officer
|
1,331
-2.2%
1.83
USD 2,436
|
1,331
-2.2%
|
1.83
|
USD 2,436
|
|
|
2023-06-22 |
2023-06-20 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
526
-0.6%
4.85
USD 2,551
|
526
-0.6%
|
4.85
|
USD 2,551
|
|
|
2023-06-22 |
2023-06-20 |
PS
Planned sale
|
Trager James
Chief Scientific Officer
Officer
|
439
-0.4%
4.85
USD 2,129
|
439
-0.4%
|
4.85
|
USD 2,129
|
|
|
2023-06-22 |
2023-06-20 |
S
Sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
221
-0.8%
4.85
USD 1,072
|
221
-0.8%
|
4.85
|
USD 1,072
|
|
|
2023-06-22 |
2023-06-20 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
1,704
-0.5%
4.85
USD 8,264
|
1,704
-0.5%
|
4.85
|
USD 8,264
|
|
|
2023-06-22 |
2023-06-20 |
S
Sale
|
Hager Alicia J.
Chief Legal Officer
Officer
|
701
-1.2%
4.85
USD 3,400
|
701
-1.2%
|
4.85
|
USD 3,400
|
|
|
2023-06-22 |
2023-06-20 |
PS
Planned sale
|
Shook David
Chief Medical Officer
Officer
|
439
-0.7%
4.85
USD 2,129
|
439
-0.7%
|
4.85
|
USD 2,129
|
|
|
2023-01-18 |
2023-01-17 |
S
Sale
|
Hager Alicia J.
Chief Legal Officer
Officer
|
1,103
-1.9%
5.49
USD 6,055
|
1,103
-1.9%
|
5.49
|
USD 6,055
|
|
|
2023-01-18 |
2023-01-17 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
3,691
-1.2%
5.49
USD 20,264
|
3,691
-1.2%
|
5.49
|
USD 20,264
|
|
|
2023-01-18 |
2023-01-17 |
S
Sale
|
Trager James
Chief Scientific Officer
Officer
|
1,115
-1.1%
5.49
USD 6,121
|
1,115
-1.1%
|
5.49
|
USD 6,121
|
|
|
2023-01-18 |
2023-01-17 |
S
Sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
491
-1.7%
5.49
USD 2,696
|
491
-1.7%
|
5.49
|
USD 2,696
|
|
|
2023-01-18 |
2023-01-17 |
S
Sale
|
Shook David
Chief Medical Officer
Officer
|
175
-0.3%
5.49
USD 961
|
175
-0.3%
|
5.49
|
USD 961
|
|
|
2023-01-18 |
2023-01-17 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
1,122
-1.3%
5.49
USD 6,160
|
1,122
-1.3%
|
5.49
|
USD 6,160
|
|
|
2022-10-07 |
2022-10-06 |
PS
Planned sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
842
-9.7%
14.02
USD 11,805
|
842
-9.7%
|
14.02
|
USD 11,805
|
|
|
2022-09-22 |
2022-09-21 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
6,126
-2.2%
13.01
USD 79,717
|
6,126
-2.2%
|
13.01
|
USD 79,717
|
|
|
2022-08-17 |
2022-08-15 |
PS
Planned sale
|
Trager James
Chief Scientific Officer
Officer
|
5,000
-7.4%
17.53
USD 87,656
|
5,000
-7.4%
|
17.53
|
USD 87,656
|
|
|
2022-08-17 |
2022-08-15 |
PS
Planned sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
11,000
-58.5%
17.64
USD 194,052
|
11,000
-58.5%
|
17.64
|
USD 194,052
|
|
|
2022-08-17 |
2022-08-15 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
7,500
-14.0%
18.03
USD 135,215
|
7,500
-14.0%
|
18.03
|
USD 135,215
|
|
|
2022-08-10 |
2022-08-08 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
7,500
-14.0%
15.32
USD 114,900
|
7,500
-14.0%
|
15.32
|
USD 114,900
|
|
|
2022-08-10 |
2022-08-08 |
PS
Planned sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
11,593
-59.8%
15.51
USD 179,783
|
11,593
-59.8%
|
15.51
|
USD 179,783
|
|
|
2022-07-26 |
2022-07-25 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
7,500
-14.0%
13.40
USD 100,480
|
7,500
-14.0%
|
13.40
|
USD 100,480
|
|
|
2022-07-26 |
2022-07-25 |
PS
Planned sale
|
Brandenberger Ralph
Chief Technical Officer
Officer
|
3,000
-27.8%
13.41
USD 40,230
|
3,000
-27.8%
|
13.41
|
USD 40,230
|
|
|
2022-06-07 |
2022-06-03 |
PS
Planned sale
|
Brandenberger Ralph
Sr. VP, Technical Operations
Officer
|
4,140
-43.9%
15.00
USD 62,100
|
4,140
-43.9%
|
15.00
|
USD 62,100
|
|
|
2022-04-29 |
2022-04-28 |
B
Purchase
|
George Simeon
Non-Executive Director
|
666,666
+inf%
15.00
USD 9,999,990
|
666,666
+inf%
|
15.00
|
USD 9,999,990
|
|
|
2022-04-29 |
2022-04-28 |
B
Purchase
|
George Simeon
Non-Executive Director
|
666,667
+inf%
15.00
USD 10,000,005
|
666,667
+inf%
|
15.00
|
USD 10,000,005
|
|
|
2022-04-28 |
2022-04-26 |
B
Purchase
|
RA CAPITAL MANAGEMENT, L.P.
Non-Executive Director
Large shareholder
|
2,200,000
+39.2%
15.00
USD 33,000,000
|
2,200,000
+39.2%
|
15.00
|
USD 33,000,000
|
|
|
2021-12-03 |
2021-12-01 |
PS
Planned sale
|
Brandenberger Ralph
Sr. VP, Technical Operations
Officer
|
4,140
-100.0%
15.64
USD 64,750
|
4,140
-100.0%
|
15.64
|
USD 64,750
|
|
|
2021-10-01 |
2021-09-29 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
223
-0.1%
26.53
USD 5,916
|
223
-0.1%
|
26.53
|
USD 5,916
|
|
|
2021-10-01 |
2021-09-29 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
8,277
-3.6%
27.20
USD 225,134
|
8,277
-3.6%
|
27.20
|
USD 225,134
|
|
|
2021-09-02 |
2021-09-01 |
PS
Planned sale
|
Brandenberger Ralph
See Remarks
Officer
|
4,140
-100.0%
32.08
USD 132,811
|
4,140
-100.0%
|
32.08
|
USD 132,811
|
|
|
2021-08-09 |
2021-08-05 |
PS
Planned sale
|
Rajangam Kanya
Chief Medical Officer
Officer
|
10,000
-100.0%
37.28
USD 372,800
|
10,000
-100.0%
|
37.28
|
USD 372,800
|
|
|
2021-07-06 |
2021-07-01 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
6,500
-19.2%
31.71
USD 206,115
|
6,500
-19.2%
|
31.71
|
USD 206,115
|
|
|
2021-06-23 |
2021-06-21 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
3,807
-1.6%
26.89
USD 102,370
|
3,807
-1.6%
|
26.89
|
USD 102,370
|
|
|
2021-06-23 |
2021-06-21 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
4,693
-2.0%
26.39
USD 123,848
|
4,693
-2.0%
|
26.39
|
USD 123,848
|
|
|
2021-06-04 |
2021-06-02 |
PS
Planned sale
|
Brandenberger Ralph
See Remarks
Officer
|
4,140
-100.0%
24.50
USD 101,430
|
4,140
-100.0%
|
24.50
|
USD 101,430
|
|
|
2021-05-12 |
2021-05-10 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
3,000
-9.5%
27.16
USD 81,480
|
3,000
-9.5%
|
27.16
|
USD 81,480
|
|
|
2021-05-05 |
2021-05-03 |
PS
Planned sale
|
Trager James
Chief Scientific Officer
Officer
|
2,250
-4.7%
31.64
USD 71,190
|
2,250
-4.7%
|
31.64
|
USD 71,190
|
|
|
2021-05-05 |
2021-05-03 |
PS
Planned sale
|
Trager James
Chief Scientific Officer
Officer
|
1,350
-2.9%
31.64
USD 42,714
|
1,350
-2.9%
|
31.64
|
USD 42,714
|
|
|
2021-04-02 |
2021-04-01 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
3,500
-10.0%
32.70
USD 114,450
|
3,500
-10.0%
|
32.70
|
USD 114,450
|
|
|
2021-04-01 |
2021-03-30 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
3,130
-1.3%
32.21
USD 100,817
|
3,130
-1.3%
|
32.21
|
USD 100,817
|
|
|
2021-04-01 |
2021-03-30 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
2,409
-1.0%
31.24
USD 75,257
|
2,409
-1.0%
|
31.24
|
USD 75,257
|
|
|
2021-04-01 |
2021-03-30 |
PS
Planned sale
|
HASTINGS PAUL J
Chief Executive Officer
Executive Director
|
11,461
-4.5%
30.23
USD 346,466
|
11,461
-4.5%
|
30.23
|
USD 346,466
|
|
|
2021-02-03 |
2021-02-02 |
PS
Planned sale
|
Trager James
Chief Scientific Officer
Officer
|
2,800
-5.6%
40.00
USD 112,000
|
2,800
-5.6%
|
40.00
|
USD 112,000
|
|
|
2021-02-03 |
2021-02-01 |
PS
Planned sale
|
Trager James
Chief Scientific Officer
Officer
|
1,566
-3.2%
39.46
USD 61,794
|
1,566
-3.2%
|
39.46
|
USD 61,794
|
|
|
2021-02-03 |
2021-02-01 |
PS
Planned sale
|
Trager James
Chief Scientific Officer
Officer
|
2,034
-4.0%
38.07
USD 77,434
|
2,034
-4.0%
|
38.07
|
USD 77,434
|
|
|
2021-01-26 |
2021-01-25 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
3,500
-10.0%
48.40
USD 169,400
|
3,500
-10.0%
|
48.40
|
USD 169,400
|
|
|
2021-01-26 |
2021-01-25 |
PS
Planned sale
|
Mahmood Nadir
See Remarks
Officer
|
2,000
-5.4%
48.86
USD 97,720
|
2,000
-5.4%
|
48.86
|
USD 97,720
|
|
|
2020-07-16 |
2020-07-14 |
B
Purchase
|
Makhzoumi Mohamad
Large shareholder
|
666,666
+29.8%
18.00
USD 11,999,988
|
666,666
+29.8%
|
18.00
|
USD 11,999,988
|
|
|
2020-07-16 |
2020-07-14 |
B
Purchase
|
GLAXOSMITHKLINE PLC
Non-Executive Director
Large shareholder
|
833,333
+36.0%
18.00
USD 14,999,994
|
833,333
+36.0%
|
18.00
|
USD 14,999,994
|
|
|
2020-07-16 |
2020-07-14 |
B
Purchase
|
RA CAPITAL MANAGEMENT, L.P.
Large shareholder
|
3,333,333
+146.7%
18.00
USD 59,999,994
|
3,333,333
+146.7%
|
18.00
|
USD 59,999,994
|
|
|
2020-07-16 |
2020-07-14 |
B
Purchase
|
SANDELL SCOTT D
Large shareholder
|
666,666
+29.8%
18.00
USD 11,999,988
|
666,666
+29.8%
|
18.00
|
USD 11,999,988
|
|
|
2020-07-16 |
2020-07-14 |
B
Purchase
|
MAKOWER JOSHUA
Large shareholder
|
666,666
+29.8%
18.00
USD 11,999,988
|
666,666
+29.8%
|
18.00
|
USD 11,999,988
|
|
|
2020-07-16 |
2020-07-14 |
B
Purchase
|
Novo Holdings A/S
Large shareholder
|
555,555
+24.8%
18.00
USD 9,999,990
|
555,555
+24.8%
|
18.00
|
USD 9,999,990
|
|
|
2020-07-16 |
2020-07-14 |
B
Purchase
|
BASKETT FOREST
Large shareholder
|
666,666
+29.8%
18.00
USD 11,999,988
|
666,666
+29.8%
|
18.00
|
USD 11,999,988
|
|
