United States Biotechnology & Medical Research

Nkarta Inc (NKTX)

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Over the last 90 days, Nkarta Inc. has seen two insider transactions, both sales totaling $9,625.92. The company's stock has experienced a 41.6% increase in the past 90 days, currently trading near its 52-week high. The last earnings report showed a slight miss on EPS.

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Ticker: NKTX Exchange: NSM

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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Company data & Insiders

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Trades

HASTINGS PAUL J

Chief Executive Officer

2 sales — total 200,000 USD

Planned sale 18 Jun 2026

Value US$3,753,715.89 | Price 84.86 | Shares 73,215

Planned sale 18 Jun 2026

Value US$1,460,777.60 | Price 221.16 | Shares 39,873

Mahmood Nadir

President

1 sale — total 11,693 USD

Sale 15 Jan 2026

Value US$3,021,897.29 | Price 494.48 | Shares 12,292

HASTINGS PAUL J

Chief Executive Officer

1 sale — total 53,915 USD

Sale 15 Jan 2026

Value US$53,915.22 | Price 2.07 | Shares 26,046

HASTINGS PAUL J

Chief Executive Officer

1 sale — total 3,204 USD

Planned sale 18 Jun 2025

Value US$3,204.10 | Price 1.79 | Shares 1,790

Hager Alicia J.

Chief Legal Officer

1 sale — total 21,085 USD

Sale 15 Jan 2025

Value US$21,084.80 | Price 2.20 | Shares 9,584

Brandenberger Ralph

Chief Technical Officer

1 sale — total 16,383 USD

Sale 15 Jan 2025

Value US$16,383.40 | Price 2.20 | Shares 7,447

HASTINGS PAUL J

Chief Executive Officer

1 sale — total 38,232 USD

Sale 15 Jan 2025

Value US$38,231.60 | Price 2.20 | Shares 17,378

Shook David

See Remarks

1 sale — total 19,004 USD

Sale 15 Jan 2025

Value US$19,003.60 | Price 2.20 | Shares 8,638

Levin Alyssa

See Remarks

1 sale — total 12,844 USD

Sale 15 Jan 2025

Value US$12,843.60 | Price 2.20 | Shares 5,838

Hager Alicia J.

Chief Legal Officer

1 sale — total 27,168 USD

Planned sale 16 Jul 2024

Value US$27,168.00 | Price 8.00 | Shares 3,396

ALICIA HAGER

Officer

1 sale — total 23,840 USD

Proposed sale 16 Jul 2024

Value US$23,839.92 | Price 7.02 | Shares 3,396

Shook David

Chief Medical Officer

1 sale — total 2,554 USD

Sale 18 Jun 2024

Value US$2,553.60 | Price 5.60 | Shares 456

Trager James

Chief Scientific Officer

1 sale — total 2,554 USD

Sale 18 Jun 2024

Value US$2,553.60 | Price 5.60 | Shares 456

Hager Alicia J.

Chief Legal Officer

1 sale — total 4,071 USD

Sale 18 Jun 2024

Value US$4,071.20 | Price 5.60 | Shares 727

HASTINGS PAUL J

Chief Executive Officer

1 sale — total 9,912 USD

Sale 18 Jun 2024

Value US$9,912.00 | Price 5.60 | Shares 1,770

Brandenberger Ralph

Chief Technical Officer

1 sale — total 1,282 USD

Sale 18 Jun 2024

Value US$1,282.40 | Price 5.60 | Shares 229

RA CAPITAL MANAGEMENT, L.P.

1 purchase — total 30,000,000 USD

Buy 27 Mar 2024

Value US$30,000,000.00 | Price 10.00 | Shares 3,000,000

George Simeon

2 purchases — total 20,000,000 USD

Buy 27 Mar 2024

Value US$4,516,590.00 | Price 10.00 | Shares 451,659

Buy 27 Mar 2024

Value US$15,483,410.00 | Price 10.00 | Shares 1,548,341

PAUL J HASTINGS

Officer

1 sale — total 770,400 USD

Proposed sale 4 Mar 2024

Value US$770,400.00 | Price 12.84 | Shares 60,000

Brandenberger Ralph

Chief Technical Officer

1 sale — total 104,671 USD

Planned sale 1 Mar 2024

Value US$104,671.17 | Price 12.51 | Shares 8,367

RALPH ERIK BRANDENBERGER

Officer

1 sale — total 101,073 USD

Proposed sale 1 Mar 2024

Value US$101,073.36 | Price 12.08 | Shares 8,367

PAUL J HASTINGS

Officer

1 sale — total 1,449,600 USD

Proposed sale 1 Mar 2024

Value US$1,449,600.00 | Price 12.08 | Shares 120,000

Trager James

Chief Scientific Officer

1 sale — total 49,716 USD

Planned sale 12 Feb 2024

Value US$49,716.00 | Price 12.00 | Shares 4,143

JAMES BARNABY TRAGER

Officer

1 sale — total 46,029 USD

Proposed sale 12 Feb 2024

Value US$46,028.73 | Price 11.11 | Shares 4,143

Brandenberger Ralph

Chief Technical Officer

1 sale — total 21,955 USD

Sale 16 Jan 2024

Value US$21,954.88 | Price 8.74 | Shares 2,512

Shook David

Chief Medical Officer

1 sale — total 31,044 USD

Sale 16 Jan 2024

Value US$31,044.48 | Price 8.74 | Shares 3,552

Trager James

Chief Scientific Officer

1 sale — total 39,854 USD

Sale 16 Jan 2024

Value US$39,854.40 | Price 8.74 | Shares 4,560

Hager Alicia J.

Chief Legal Officer

1 sale — total 39,802 USD

Sale 16 Jan 2024

Value US$39,801.96 | Price 8.74 | Shares 4,554

HASTINGS PAUL J

Chief Executive Officer

1 sale — total 84,752 USD

Sale 16 Jan 2024

Value US$84,751.78 | Price 8.74 | Shares 9,697

Shook David

Chief Medical Officer

1 sale — total 2,436 USD

Sale 21 Aug 2023

Value US$2,435.73 | Price 1.83 | Shares 1,331

Mahmood Nadir

See Remarks

1 sale — total 2,551 USD

Planned sale 20 Jun 2023

Value US$2,551.10 | Price 4.85 | Shares 526

Trager James

Chief Scientific Officer

1 sale — total 2,129 USD

Planned sale 20 Jun 2023

Value US$2,129.15 | Price 4.85 | Shares 439

Brandenberger Ralph

Chief Technical Officer

1 sale — total 1,072 USD

Sale 20 Jun 2023

Value US$1,071.85 | Price 4.85 | Shares 221

HASTINGS PAUL J

Chief Executive Officer

1 sale — total 8,264 USD

Planned sale 20 Jun 2023

Value US$8,264.40 | Price 4.85 | Shares 1,704

Hager Alicia J.

Chief Legal Officer

1 sale — total 3,400 USD

Sale 20 Jun 2023

Value US$3,399.85 | Price 4.85 | Shares 701

Shook David

Chief Medical Officer

1 sale — total 2,129 USD

Planned sale 20 Jun 2023

Value US$2,129.15 | Price 4.85 | Shares 439

Hager Alicia J.

Chief Legal Officer

1 sale — total 6,055 USD

Sale 17 Jan 2023

Value US$6,055.47 | Price 5.49 | Shares 1,103

HASTINGS PAUL J

Chief Executive Officer

1 sale — total 20,264 USD

Planned sale 17 Jan 2023

Value US$20,263.59 | Price 5.49 | Shares 3,691

Trager James

Chief Scientific Officer

1 sale — total 6,121 USD

Sale 17 Jan 2023

Value US$6,121.35 | Price 5.49 | Shares 1,115

Brandenberger Ralph

Chief Technical Officer

1 sale — total 2,696 USD

Sale 17 Jan 2023

Value US$2,695.59 | Price 5.49 | Shares 491

Shook David

Chief Medical Officer

1 sale — total 961 USD

Sale 17 Jan 2023

Value US$960.75 | Price 5.49 | Shares 175

Mahmood Nadir

See Remarks

1 sale — total 6,160 USD

Planned sale 17 Jan 2023

Value US$6,159.78 | Price 5.49 | Shares 1,122

Brandenberger Ralph

Chief Technical Officer

1 sale — total 11,805 USD

Planned sale 6 Oct 2022

Value US$11,804.84 | Price 14.02 | Shares 842

HASTINGS PAUL J

Chief Executive Officer

1 sale — total 79,717 USD

Planned sale 21 Sep 2022

Value US$79,717.03 | Price 13.01 | Shares 6,126

Trager James

Chief Scientific Officer

1 sale — total 87,656 USD

Planned sale 15 Aug 2022

Value US$87,655.50 | Price 17.53 | Shares 5,000

Brandenberger Ralph

Chief Technical Officer

1 sale — total 194,052 USD

Planned sale 15 Aug 2022

Value US$194,052.10 | Price 17.64 | Shares 11,000

Mahmood Nadir

See Remarks

1 sale — total 135,215 USD

Planned sale 15 Aug 2022

Value US$135,215.25 | Price 18.03 | Shares 7,500

Mahmood Nadir

See Remarks

1 sale — total 114,900 USD

Planned sale 8 Aug 2022

Value US$114,900.00 | Price 15.32 | Shares 7,500

Brandenberger Ralph

Chief Technical Officer

1 sale — total 179,783 USD

Planned sale 8 Aug 2022

Value US$179,783.08 | Price 15.51 | Shares 11,593

Mahmood Nadir

See Remarks

1 sale — total 100,480 USD

Planned sale 25 Jul 2022

Value US$100,479.75 | Price 13.40 | Shares 7,500

Brandenberger Ralph

Chief Technical Officer

1 sale — total 40,230 USD

Planned sale 25 Jul 2022

Value US$40,230.30 | Price 13.41 | Shares 3,000

Brandenberger Ralph

Sr. VP, Technical Operations

1 sale — total 62,100 USD

Planned sale 3 Jun 2022

Value US$62,100.00 | Price 15.00 | Shares 4,140

George Simeon

2 purchases — total 19,999,995 USD

Buy 28 Apr 2022

Value US$9,999,990.00 | Price 15.00 | Shares 666,666

Buy 28 Apr 2022

Value US$10,000,005.00 | Price 15.00 | Shares 666,667

RA CAPITAL MANAGEMENT, L.P.

1 purchase — total 33,000,000 USD

Buy 26 Apr 2022

Value US$33,000,000.00 | Price 15.00 | Shares 2,200,000

Brandenberger Ralph

Sr. VP, Technical Operations

1 sale — total 64,750 USD

Planned sale 1 Dec 2021

Value US$64,749.60 | Price 15.64 | Shares 4,140

HASTINGS PAUL J

Chief Executive Officer

2 sales — total 231,051 USD

Planned sale 29 Sep 2021

Value US$5,916.19 | Price 26.53 | Shares 223

Planned sale 29 Sep 2021

Value US$225,134.40 | Price 27.20 | Shares 8,277

Brandenberger Ralph

See Remarks

1 sale — total 132,811 USD

Planned sale 1 Sep 2021

Value US$132,811.20 | Price 32.08 | Shares 4,140

Rajangam Kanya

Chief Medical Officer

1 sale — total 372,800 USD

Planned sale 5 Aug 2021

Value US$372,800.00 | Price 37.28 | Shares 10,000

Mahmood Nadir

See Remarks

1 sale — total 206,115 USD

Planned sale 1 Jul 2021

Value US$206,115.00 | Price 31.71 | Shares 6,500

HASTINGS PAUL J

Chief Executive Officer

2 sales — total 226,219 USD

Planned sale 21 Jun 2021

Value US$102,370.23 | Price 26.89 | Shares 3,807

Planned sale 21 Jun 2021

Value US$123,848.27 | Price 26.39 | Shares 4,693

Brandenberger Ralph

See Remarks

1 sale — total 101,430 USD

Planned sale 2 Jun 2021

Value US$101,430.00 | Price 24.50 | Shares 4,140

Mahmood Nadir

See Remarks

1 sale — total 81,480 USD

Planned sale 10 May 2021

Value US$81,480.00 | Price 27.16 | Shares 3,000

Trager James

Chief Scientific Officer

2 sales — total 113,904 USD

Planned sale 3 May 2021

Value US$71,190.00 | Price 31.64 | Shares 2,250

Planned sale 3 May 2021

Value US$42,714.00 | Price 31.64 | Shares 1,350

Mahmood Nadir

See Remarks

1 sale — total 114,450 USD

Planned sale 1 Apr 2021

Value US$114,450.00 | Price 32.70 | Shares 3,500

HASTINGS PAUL J

Chief Executive Officer

3 sales — total 522,540 USD

Planned sale 30 Mar 2021

Value US$100,817.30 | Price 32.21 | Shares 3,130

Planned sale 30 Mar 2021

Value US$75,257.16 | Price 31.24 | Shares 2,409

Planned sale 30 Mar 2021

Value US$346,466.03 | Price 30.23 | Shares 11,461

Trager James

Chief Scientific Officer

1 sale — total 112,000 USD

Planned sale 2 Feb 2021

Value US$112,000.00 | Price 40.00 | Shares 2,800

Trager James

Chief Scientific Officer

1 sale — total 61,794 USD

Planned sale 1 Feb 2021

Value US$61,794.36 | Price 39.46 | Shares 1,566

Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Insider and/or position	Nb. shares Price Value	Number of shares	Price	Value
2026-06-22	2026-06-18	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	73,215 -23.6% 84.86 US$3,753,716	73,215 -23.6%	84.86	US$3,753,716
2026-06-22	2026-06-18	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	39,873 +45.7% 221.16 US$1,460,778	39,873 +45.7%	221.16	US$1,460,778
2026-01-20	2026-01-15	S Sale	1.3 Mahmood Nadir President Officer	12,292 -12.7% 494.48 US$3,021,897	12,292 -12.7%	494.48	US$3,021,897
2026-01-20	2026-01-15	S Sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	26,046 -6.3% 2.07 US$53,915	26,046 -6.3%	2.07	US$53,915
2025-06-20	2025-06-18	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	1,790 -0.6% 1.79 US$3,204	1,790 -0.6%	1.79	US$3,204
2025-01-17	2025-01-15	S Sale	3.3 Hager Alicia J. Chief Legal Officer Officer	9,584 -6.1% 2.20 US$21,085	9,584 -6.1%	2.20	US$21,085
2025-01-17	2025-01-15	S Sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	7,447 -5.6% 2.20 US$16,383	7,447 -5.6%	2.20	US$16,383
2025-01-17	2025-01-15	S Sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	17,378 -5.2% 2.20 US$38,232	17,378 -5.2%	2.20	US$38,232
2025-01-17	2025-01-15	S Sale	3.1 Shook David See Remarks Officer	8,638 -4.3% 2.20 US$19,004	8,638 -4.3%	2.20	US$19,004
2025-01-17	2025-01-15	S Sale	2.5 Levin Alyssa See Remarks Officer	5,838 -5.4% 2.20 US$12,844	5,838 -5.4%	2.20	US$12,844
2024-07-18	2024-07-16	PlS Planned sale	3.3 Hager Alicia J. Chief Legal Officer Officer	3,396 -3.2% 8.00 US$27,168	3,396 -3.2%	8.00	US$27,168
2024-07-16	2024-07-16	PrS Proposed sale	3.3 ALICIA HAGER Officer Officer	3,396 7.02 US$23,840	3,396	7.02	US$23,840
2024-06-20	2024-06-18	S Sale	3.1 Shook David Chief Medical Officer Officer	456 -0.4% 5.60 US$2,554	456 -0.4%	5.60	US$2,554
2024-06-20	2024-06-18	S Sale	2.9 Trager James Chief Scientific Officer Officer	456 -0.3% 5.60 US$2,554	456 -0.3%	5.60	US$2,554
2024-06-20	2024-06-18	S Sale	3.3 Hager Alicia J. Chief Legal Officer Officer	727 -0.7% 5.60 US$4,071	727 -0.7%	5.60	US$4,071
2024-06-20	2024-06-18	S Sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	1,770 -0.7% 5.60 US$9,912	1,770 -0.7%	5.60	US$9,912
2024-06-20	2024-06-18	S Sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	229 -0.3% 5.60 US$1,282	229 -0.3%	5.60	US$1,282
2024-03-29	2024-03-27	B Purchase	2.9 RA CAPITAL MANAGEMENT, L.P. Non-Executive Director Large shareholder	3,000,000 +42.5% 10.00 US$30,000,000	3,000,000 +42.5%	10.00	US$30,000,000
2024-03-28	2024-03-27	B Purchase	3.1 George Simeon Non-Executive Director	451,659 +inf% 10.00 US$4,516,590	451,659 +inf%	10.00	US$4,516,590
2024-03-28	2024-03-27	B Purchase	3.1 George Simeon Non-Executive Director	1,548,341 +inf% 10.00 US$15,483,410	1,548,341 +inf%	10.00	US$15,483,410
2024-03-04	2024-03-04	PrS Proposed sale	2.8 PAUL J HASTINGS Officer Officer	60,000 12.84 US$770,400	60,000	12.84	US$770,400
2024-03-05	2024-03-01	PlS Planned sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	8,367 -9.5% 12.51 US$104,671	8,367 -9.5%	12.51	US$104,671
2024-03-01	2024-03-01	PrS Proposed sale	3.3 RALPH ERIK BRANDENBERGER Officer Officer	8,367 12.08 US$101,073	8,367	12.08	US$101,073
2024-03-01	2024-03-01	PrS Proposed sale	2.8 PAUL J HASTINGS Officer Officer	120,000 12.08 US$1,449,600	120,000	12.08	US$1,449,600
2024-02-14	2024-02-12	PlS Planned sale	2.9 Trager James Chief Scientific Officer Officer	4,143 -2.7% 12.00 US$49,716	4,143 -2.7%	12.00	US$49,716
2024-02-12	2024-02-12	PrS Proposed sale	2.9 JAMES BARNABY TRAGER Officer Officer	4,143 11.11 US$46,029	4,143	11.11	US$46,029
2024-01-18	2024-01-16	S Sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	2,512 -3.0% 8.74 US$21,955	2,512 -3.0%	8.74	US$21,955
2024-01-18	2024-01-16	S Sale	3.1 Shook David Chief Medical Officer Officer	3,552 -3.0% 8.74 US$31,044	3,552 -3.0%	8.74	US$31,044
2024-01-18	2024-01-16	S Sale	2.9 Trager James Chief Scientific Officer Officer	4,560 -2.9% 8.74 US$39,854	4,560 -2.9%	8.74	US$39,854
2024-01-18	2024-01-16	S Sale	3.3 Hager Alicia J. Chief Legal Officer Officer	4,554 -4.0% 8.74 US$39,802	4,554 -4.0%	8.74	US$39,802
2024-01-18	2024-01-16	S Sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	9,697 -2.4% 8.74 US$84,752	9,697 -2.4%	8.74	US$84,752
2023-08-23	2023-08-21	S Sale	3.1 Shook David Chief Medical Officer Officer	1,331 -2.2% 1.83 US$2,436	1,331 -2.2%	1.83	US$2,436
2023-06-22	2023-06-20	PlS Planned sale	1.3 Mahmood Nadir See Remarks Officer	526 -0.6% 4.85 US$2,551	526 -0.6%	4.85	US$2,551
2023-06-22	2023-06-20	PlS Planned sale	2.9 Trager James Chief Scientific Officer Officer	439 -0.4% 4.85 US$2,129	439 -0.4%	4.85	US$2,129
2023-06-22	2023-06-20	S Sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	221 -0.8% 4.85 US$1,072	221 -0.8%	4.85	US$1,072
2023-06-22	2023-06-20	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	1,704 -0.5% 4.85 US$8,264	1,704 -0.5%	4.85	US$8,264
2023-06-22	2023-06-20	S Sale	3.3 Hager Alicia J. Chief Legal Officer Officer	701 -1.2% 4.85 US$3,400	701 -1.2%	4.85	US$3,400
2023-06-22	2023-06-20	PlS Planned sale	3.1 Shook David Chief Medical Officer Officer	439 -0.7% 4.85 US$2,129	439 -0.7%	4.85	US$2,129
2023-01-18	2023-01-17	S Sale	3.3 Hager Alicia J. Chief Legal Officer Officer	1,103 -1.9% 5.49 US$6,055	1,103 -1.9%	5.49	US$6,055
2023-01-18	2023-01-17	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	3,691 -1.2% 5.49 US$20,264	3,691 -1.2%	5.49	US$20,264
2023-01-18	2023-01-17	S Sale	2.9 Trager James Chief Scientific Officer Officer	1,115 -1.1% 5.49 US$6,121	1,115 -1.1%	5.49	US$6,121
2023-01-18	2023-01-17	S Sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	491 -1.7% 5.49 US$2,696	491 -1.7%	5.49	US$2,696
2023-01-18	2023-01-17	S Sale	3.1 Shook David Chief Medical Officer Officer	175 -0.3% 5.49 US$961	175 -0.3%	5.49	US$961
2023-01-18	2023-01-17	PlS Planned sale	1.3 Mahmood Nadir See Remarks Officer	1,122 -1.3% 5.49 US$6,160	1,122 -1.3%	5.49	US$6,160
2022-10-07	2022-10-06	PlS Planned sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	842 -9.7% 14.02 US$11,805	842 -9.7%	14.02	US$11,805
2022-09-22	2022-09-21	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	6,126 -2.2% 13.01 US$79,717	6,126 -2.2%	13.01	US$79,717
2022-08-17	2022-08-15	PlS Planned sale	2.9 Trager James Chief Scientific Officer Officer	5,000 -7.4% 17.53 US$87,656	5,000 -7.4%	17.53	US$87,656
2022-08-17	2022-08-15	PlS Planned sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	11,000 -58.5% 17.64 US$194,052	11,000 -58.5%	17.64	US$194,052
2022-08-17	2022-08-15	PlS Planned sale	1.3 Mahmood Nadir See Remarks Officer	7,500 -14.0% 18.03 US$135,215	7,500 -14.0%	18.03	US$135,215
2022-08-10	2022-08-08	PlS Planned sale	1.3 Mahmood Nadir See Remarks Officer	7,500 -14.0% 15.32 US$114,900	7,500 -14.0%	15.32	US$114,900
2022-08-10	2022-08-08	PlS Planned sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	11,593 -59.8% 15.51 US$179,783	11,593 -59.8%	15.51	US$179,783
2022-07-26	2022-07-25	PlS Planned sale	1.3 Mahmood Nadir See Remarks Officer	7,500 -14.0% 13.40 US$100,480	7,500 -14.0%	13.40	US$100,480
2022-07-26	2022-07-25	PlS Planned sale	3.3 Brandenberger Ralph Chief Technical Officer Officer	3,000 -27.8% 13.41 US$40,230	3,000 -27.8%	13.41	US$40,230
2022-06-07	2022-06-03	PlS Planned sale	3.3 Brandenberger Ralph Sr. VP, Technical Operations Officer	4,140 -43.9% 15.00 US$62,100	4,140 -43.9%	15.00	US$62,100
2022-04-29	2022-04-28	B Purchase	3.1 George Simeon Non-Executive Director	666,666 +inf% 15.00 US$9,999,990	666,666 +inf%	15.00	US$9,999,990
2022-04-29	2022-04-28	B Purchase	3.1 George Simeon Non-Executive Director	666,667 +inf% 15.00 US$10,000,005	666,667 +inf%	15.00	US$10,000,005
2022-04-28	2022-04-26	B Purchase	2.9 RA CAPITAL MANAGEMENT, L.P. Non-Executive Director Large shareholder	2,200,000 +39.2% 15.00 US$33,000,000	2,200,000 +39.2%	15.00	US$33,000,000
2021-12-03	2021-12-01	PlS Planned sale	3.3 Brandenberger Ralph Sr. VP, Technical Operations Officer	4,140 -100.0% 15.64 US$64,750	4,140 -100.0%	15.64	US$64,750
2021-10-01	2021-09-29	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	223 -0.1% 26.53 US$5,916	223 -0.1%	26.53	US$5,916
2021-10-01	2021-09-29	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	8,277 -3.6% 27.20 US$225,134	8,277 -3.6%	27.20	US$225,134
2021-09-02	2021-09-01	PlS Planned sale	3.3 Brandenberger Ralph See Remarks Officer	4,140 -100.0% 32.08 US$132,811	4,140 -100.0%	32.08	US$132,811
2021-08-09	2021-08-05	PlS Planned sale	3.5 Rajangam Kanya Chief Medical Officer Officer	10,000 -100.0% 37.28 US$372,800	10,000 -100.0%	37.28	US$372,800
2021-07-06	2021-07-01	PlS Planned sale	1.3 Mahmood Nadir See Remarks Officer	6,500 -19.2% 31.71 US$206,115	6,500 -19.2%	31.71	US$206,115
2021-06-23	2021-06-21	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	3,807 -1.6% 26.89 US$102,370	3,807 -1.6%	26.89	US$102,370
2021-06-23	2021-06-21	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	4,693 -2.0% 26.39 US$123,848	4,693 -2.0%	26.39	US$123,848
2021-06-04	2021-06-02	PlS Planned sale	3.3 Brandenberger Ralph See Remarks Officer	4,140 -100.0% 24.50 US$101,430	4,140 -100.0%	24.50	US$101,430
2021-05-12	2021-05-10	PlS Planned sale	1.3 Mahmood Nadir See Remarks Officer	3,000 -9.5% 27.16 US$81,480	3,000 -9.5%	27.16	US$81,480
2021-05-05	2021-05-03	PlS Planned sale	2.9 Trager James Chief Scientific Officer Officer	2,250 -4.7% 31.64 US$71,190	2,250 -4.7%	31.64	US$71,190
2021-05-05	2021-05-03	PlS Planned sale	2.9 Trager James Chief Scientific Officer Officer	1,350 -2.9% 31.64 US$42,714	1,350 -2.9%	31.64	US$42,714
2021-04-02	2021-04-01	PlS Planned sale	1.3 Mahmood Nadir See Remarks Officer	3,500 -10.0% 32.70 US$114,450	3,500 -10.0%	32.70	US$114,450
2021-04-01	2021-03-30	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	3,130 -1.3% 32.21 US$100,817	3,130 -1.3%	32.21	US$100,817
2021-04-01	2021-03-30	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	2,409 -1.0% 31.24 US$75,257	2,409 -1.0%	31.24	US$75,257
2021-04-01	2021-03-30	PlS Planned sale	2.8 HASTINGS PAUL J Chief Executive Officer Executive Director	11,461 -4.5% 30.23 US$346,466	11,461 -4.5%	30.23	US$346,466
2021-02-03	2021-02-02	PlS Planned sale	2.9 Trager James Chief Scientific Officer Officer	2,800 -5.6% 40.00 US$112,000	2,800 -5.6%	40.00	US$112,000
2021-02-03	2021-02-01	PlS Planned sale	2.9 Trager James Chief Scientific Officer Officer	1,566 -3.2% 39.46 US$61,794	1,566 -3.2%	39.46	US$61,794

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