Madrigal Pharmaceuticals Inc (MDGL)

Over the past 90 days, Madrigal Pharmaceuticals Inc. saw 28 insider transactions, all of which were sales, totaling approximately $1.8 million in net value. Key executives, including CEO William Sibold and CMO David Soergel, conducted these disposals. These activities follow the company's May 2026 earnings report, where the firm outperformed EPS expectations by 66.7%.
Ticker: MDGL Exchange: NAS


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Insider trades have triggered activity signals for Madrigal Pharmaceuticals Inc. Upgrade to see score, net flow, insiders and the full signal context.

Top insiders
Trades
Sibold William John
President and CEO
10 sales — total 1,000,000 USD
Sale 20 Jul 2026
Value US$4,281,081.40 | Price 193.23 | Shares 13,578
Sale 20 Jul 2026
Value US$2,580,042.83 | Price 436.25 | Shares 10,069
Sale 20 Jul 2026
Value US$100,000.00 | Price 550.01 | Shares 1,000
Sale 20 Jul 2026
Value US$100,000.00 | Price 548.87 | Shares 1,000
Sale 20 Jul 2026
Value US$100,000.00 | Price 547.70 | Shares 1,000
Sale 20 Jul 2026
Value US$100,000.00 | Price 547.08 | Shares 1,000
Sale 20 Jul 2026
Value US$100,000.00 | Price 545.71 | Shares 1,000
Sale 20 Jul 2026
Value US$100,000.00 | Price 544.71 | Shares 1,000
Sale 20 Jul 2026
Value US$100,000.00 | Price 543.79 | Shares 1,000
Sale 20 Jul 2026
Value US$100,000.00 | Price 542.75 | Shares 1,000
Proposed sale 20 Jul 2026
Value US$2,608,706.82 | Price 151.99 | Shares 60,650
Planned sale 1 Jun 2026
Value US$516,561.08 | Price 495.74 | Shares 1,042
Proposed sale 1 Jun 2026
Value US$518,155.34 | Price 497.27 | Shares 1,042
Planned sale 22 May 2026
Value US$41,598.40 | Price 519.98 | Shares 80
Planned sale 22 May 2026
Value US$405,668.76 | Price 518.76 | Shares 782
Planned sale 22 May 2026
Value US$774,835.37 | Price 517.59 | Shares 1,497
Planned sale 22 May 2026
Value US$373,693.97 | Price 516.87 | Shares 723
Planned sale 22 May 2026
Value US$338,960.69 | Price 515.92 | Shares 657
Planned sale 22 May 2026
Value US$176,531.50 | Price 514.67 | Shares 343
Planned sale 22 May 2026
Value US$20,518.80 | Price 512.97 | Shares 40
Planned sale 22 May 2026
Value US$224,988.47 | Price 512.50 | Shares 439
Planned sale 22 May 2026
Value US$311,951.99 | Price 511.40 | Shares 610
Planned sale 22 May 2026
Value US$77,064.04 | Price 510.36 | Shares 151
Planned sale 22 May 2026
Value US$162,637.44 | Price 508.24 | Shares 320
Planned sale 22 May 2026
Value US$20,267.00 | Price 506.68 | Shares 40
Proposed sale 22 May 2026
Value US$2,918,218.38 | Price 513.59 | Shares 5,682
Proposed sale 18 May 2026
Value US$441,994.36 | Price 523.69 | Shares 844
Sale 18 May 2026
Value US$435,419.60 | Price 515.90 | Shares 844
Planned sale 6 Mar 2026
Value US$17,506.00 | Price 437.65 | Shares 40
Planned sale 6 Mar 2026
Value US$34,935.20 | Price 436.69 | Shares 80
Planned sale 6 Mar 2026
Value US$34,825.20 | Price 435.32 | Shares 80
Planned sale 6 Mar 2026
Value US$69,472.00 | Price 434.20 | Shares 160
Planned sale 6 Mar 2026
Value US$50,176.48 | Price 432.56 | Shares 116
Planned sale 6 Mar 2026
Value US$51,708.40 | Price 430.90 | Shares 120
Planned sale 6 Mar 2026
Value US$17,183.20 | Price 429.58 | Shares 40
Planned sale 6 Mar 2026
Value US$68,639.20 | Price 429.00 | Shares 160
Planned sale 6 Mar 2026
Value US$34,227.60 | Price 427.85 | Shares 80
Planned sale 6 Mar 2026
Value US$179,282.80 | Price 426.86 | Shares 420
Planned sale 6 Mar 2026
Value US$17,003.20 | Price 425.08 | Shares 40
Sale 6 Mar 2026
Value US$279,033.24 | Price 431.94 | Shares 646
Proposed sale 6 Mar 2026
Value US$283,813.64 | Price 439.34 | Shares 646
Sale 6 Mar 2026
Value US$718,316.22 | Price 431.94 | Shares 1,663
Proposed sale 6 Mar 2026
Value US$730,622.42 | Price 439.34 | Shares 1,663
Sale 6 Mar 2026
Value US$155,498.40 | Price 431.94 | Shares 360
Proposed sale 6 Mar 2026
Value US$158,162.40 | Price 439.34 | Shares 360
Sale 6 Mar 2026
Value US$180,982.86 | Price 431.94 | Shares 419
Proposed sale 6 Mar 2026
Value US$184,083.46 | Price 439.34 | Shares 419
Sale 6 Mar 2026
Value US$212,082.54 | Price 431.94 | Shares 491
Proposed sale 6 Mar 2026
Value US$215,715.94 | Price 439.34 | Shares 491
Proposed sale 6 Mar 2026
Value US$586,958.24 | Price 439.34 | Shares 1,336
Sale 2 Mar 2026
Value US$505,389.43 | Price 427.21 | Shares 1,183
Proposed sale 2 Mar 2026
Value US$511,056.00 | Price 432.00 | Shares 1,183
Proposed sale 26 Jan 2026
Value US$273,856.50 | Price 480.45 | Shares 570
Proposed sale 26 Jan 2026
Value US$163,353.00 | Price 480.45 | Shares 340
Proposed sale 26 Jan 2026
Value US$757,669.65 | Price 480.45 | Shares 1,577
Proposed sale 26 Jan 2026
Value US$310,851.15 | Price 480.45 | Shares 647
Planned sale 26 Jan 2026
Value US$281,916.30 | Price 494.59 | Shares 570
Sale 26 Jan 2026
Value US$167,422.80 | Price 492.42 | Shares 340
Sale 26 Jan 2026
Value US$776,546.34 | Price 492.42 | Shares 1,577
Sale 26 Jan 2026
Value US$318,595.74 | Price 492.42 | Shares 647
Proposed sale 20 Jan 2026
Value US$215,220.72 | Price 501.68 | Shares 429
Proposed sale 20 Jan 2026
Value US$131,941.84 | Price 501.68 | Shares 263
Proposed sale 20 Jan 2026
Value US$1,122,759.84 | Price 501.68 | Shares 2,238
Planned sale 20 Jan 2026
Value US$215,100.60 | Price 501.40 | Shares 429
Sale 20 Jan 2026
Value US$129,072.51 | Price 490.77 | Shares 263
Sale 20 Jan 2026
Value US$1,098,343.26 | Price 490.77 | Shares 2,238
Planned sale 9 Jan 2026
Value US$21,831.60 | Price 545.79 | Shares 40
Planned sale 9 Jan 2026
Value US$324,214.80 | Price 540.36 | Shares 600
Planned sale 9 Jan 2026
Value US$258,831.22 | Price 539.23 | Shares 480
Planned sale 9 Jan 2026
Value US$43,027.60 | Price 537.85 | Shares 80
Planned sale 9 Jan 2026
Value US$261,459.00 | Price 536.88 | Shares 487
Planned sale 9 Jan 2026
Value US$253,537.74 | Price 536.02 | Shares 473
Planned sale 9 Jan 2026
Value US$79,222.71 | Price 535.29 | Shares 148
Planned sale 9 Jan 2026
Value US$177,342.38 | Price 534.16 | Shares 332
Planned sale 9 Jan 2026
Value US$42,600.00 | Price 532.50 | Shares 80
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value
Number of shares Price Value Details
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
13,578 -10.5%
193.23
US$4,281,081
13,578 -10.5% 193.23 US$4,281,081
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
10,069 -28.4%
436.25
US$2,580,043
10,069 -28.4% 436.25 US$2,580,043
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
22,601 +14.3%
191.86
US$503,650
22,601 +14.3% 191.86 US$503,650
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
1,000 -0.0%
548.87
US$100,000
1,000 -0.0% 548.87 US$100,000
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
1,000 -0.3%
547.70
US$100,000
1,000 -0.3% 547.70 US$100,000
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
1,000 -0.1%
547.08
US$100,000
1,000 -0.1% 547.08 US$100,000
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
1,000 -0.1%
545.71
US$100,000
1,000 -0.1% 545.71 US$100,000
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
1,000 -0.3%
544.71
US$100,000
1,000 -0.3% 544.71 US$100,000
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
1,000 -0.1%
543.79
US$100,000
1,000 -0.1% 543.79 US$100,000
2026-07-20 2026-07-20 S Sale

President and CEO

Executive Director
1,000 -0.1%
542.75
US$100,000
1,000 -0.1% 542.75 US$100,000
2026-07-20 2026-07-20 PrS Proposed sale

Officer and Director

Executive Director
1,000
553.48
US$100,000
1,000 553.48 US$100,000
2026-06-01 2026-06-01 PlS Planned sale

Chief Medical Officer

Officer
1,042 -9.4%
495.74
US$516,561
1,042 -9.4% 495.74 US$516,561
2026-06-01 2026-06-01 PrS Proposed sale

Officer

Officer
1,042
497.27
US$518,155
1,042 497.27 US$518,155
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
80 -0.4%
519.98
US$41,598
80 -0.4% 519.98 US$41,598
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
782 -3.4%
518.76
US$405,669
782 -3.4% 518.76 US$405,669
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
1,497 -6.1%
517.59
US$774,835
1,497 -6.1% 517.59 US$774,835
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
723 -2.9%
516.87
US$373,694
723 -2.9% 516.87 US$373,694
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
657 -2.6%
515.92
US$338,961
657 -2.6% 515.92 US$338,961
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
343 -1.3%
514.67
US$176,532
343 -1.3% 514.67 US$176,532
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
40 -0.2%
512.97
US$20,519
40 -0.2% 512.97 US$20,519
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
439 -1.7%
512.50
US$224,988
439 -1.7% 512.50 US$224,988
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
610 -2.2%
511.40
US$311,952
610 -2.2% 511.40 US$311,952
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
151 -0.6%
510.36
US$77,064
151 -0.6% 510.36 US$77,064
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
320 -1.2%
508.24
US$162,637
320 -1.2% 508.24 US$162,637
2026-05-22 2026-05-22 PlS Planned sale Non-Executive Director
40 -0.1%
506.68
US$20,267
40 -0.1% 506.68 US$20,267
2026-05-22 2026-05-22 PrS Proposed sale

Director

Non-Executive Director
5,682
513.59
US$2,918,218
5,682 513.59 US$2,918,218
2026-05-18 2026-05-18 PrS Proposed sale

Officer

Officer
844
523.69
US$441,994
844 523.69 US$441,994
2026-05-18 2026-05-18 S Sale

Chief Medical Officer

Officer
844 -7.1%
515.90
US$435,420
844 -7.1% 515.90 US$435,420
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
40 -0.3%
437.65
US$17,506
40 -0.3% 437.65 US$17,506
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
80 -0.6%
436.69
US$34,935
80 -0.6% 436.69 US$34,935
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
80 -0.6%
435.32
US$34,825
80 -0.6% 435.32 US$34,825
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
160 -1.2%
434.20
US$69,472
160 -1.2% 434.20 US$69,472
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
116 -0.9%
432.56
US$50,176
116 -0.9% 432.56 US$50,176
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
120 -0.9%
430.90
US$51,708
120 -0.9% 430.90 US$51,708
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
40 -0.3%
429.58
US$17,183
40 -0.3% 429.58 US$17,183
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
160 -1.2%
429.00
US$68,639
160 -1.2% 429.00 US$68,639
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
80 -0.6%
427.85
US$34,228
80 -0.6% 427.85 US$34,228
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
420 -3.0%
426.86
US$179,283
420 -3.0% 426.86 US$179,283
2026-03-06 2026-03-06 PlS Planned sale

EVP and CFO

Officer
40 -0.3%
425.08
US$17,003
40 -0.3% 425.08 US$17,003
2026-03-06 2026-03-06 S Sale

EVP and CFO

Officer
646 -4.5%
431.94
US$279,033
646 -4.5% 431.94 US$279,033
2026-03-06 2026-03-06 PrS Proposed sale

Officer

Officer
646
439.34
US$283,814
646 439.34 US$283,814
2026-03-06 2026-03-06 S Sale

President and CEO

Executive Director
1,663 -1.0%
431.94
US$718,316
1,663 -1.0% 431.94 US$718,316
2026-03-06 2026-03-06 PrS Proposed sale

Officer and Director

Executive Director
1,663
439.34
US$730,622
1,663 439.34 US$730,622
2026-03-06 2026-03-06 S Sale

General Counsel

Officer
360 -2.9%
431.94
US$155,498
360 -2.9% 431.94 US$155,498
2026-03-06 2026-03-06 PrS Proposed sale

Officer

Officer
360
439.34
US$158,162
360 439.34 US$158,162
2026-03-06 2026-03-06 S Sale

Chief Commercial Officer

Officer
419 -3.2%
431.94
US$180,983
419 -3.2% 431.94 US$180,983
2026-03-06 2026-03-06 PrS Proposed sale

Officer

Officer
419
439.34
US$184,083
419 439.34 US$184,083
2026-03-06 2026-03-06 S Sale Non-Executive Director
491 -0.1%
431.94
US$212,083
491 -0.1% 431.94 US$212,083
2026-03-06 2026-03-06 PrS Proposed sale

Director

Non-Executive Director
491
439.34
US$215,716
491 439.34 US$215,716
2026-03-06 2026-03-06 PrS Proposed sale

Officer

Officer
1,336
439.34
US$586,958
1,336 439.34 US$586,958
2026-03-02 2026-03-02 S Sale

EVP and CFO

Officer
1,183 -11.3%
427.21
US$505,389
1,183 -11.3% 427.21 US$505,389
2026-03-02 2026-03-02 PrS Proposed sale

Officer

Officer
1,183
432.00
US$511,056
1,183 432.00 US$511,056
2026-01-26 2026-01-26 PrS Proposed sale

Officer

Officer
570
480.45
US$273,856
570 480.45 US$273,856
2026-01-26 2026-01-26 PrS Proposed sale

Officer

Officer
340
480.45
US$163,353
340 480.45 US$163,353
2026-01-26 2026-01-26 PrS Proposed sale

Officer and Director

Executive Director
1,577
480.45
US$757,670
1,577 480.45 US$757,670
2026-01-26 2026-01-26 PrS Proposed sale

Director

Non-Executive Director
647
480.45
US$310,851
647 480.45 US$310,851
2026-01-26 2026-01-26 PlS Planned sale

Chief Commercial Officer

Officer
570 -5.9%
494.59
US$281,916
570 -5.9% 494.59 US$281,916
2026-01-26 2026-01-26 S Sale

Chief Commercial Officer

Officer
340 -3.4%
492.42
US$167,423
340 -3.4% 492.42 US$167,423
2026-01-26 2026-01-26 S Sale

President and CEO

Executive Director
1,577 -1.1%
492.42
US$776,546
1,577 -1.1% 492.42 US$776,546
2026-01-26 2026-01-26 S Sale Non-Executive Director
647 -0.1%
492.42
US$318,596
647 -0.1% 492.42 US$318,596
2026-01-20 2026-01-20 PrS Proposed sale

Officer

Officer
429
501.68
US$215,221
429 501.68 US$215,221
2026-01-20 2026-01-20 PrS Proposed sale

Officer

Officer
263
501.68
US$131,942
263 501.68 US$131,942
2026-01-20 2026-01-20 PrS Proposed sale

Director

Non-Executive Director
2,238
501.68
US$1,122,760
2,238 501.68 US$1,122,760
2026-01-20 2026-01-20 PlS Planned sale

General Counsel

Officer
429 -4.8%
501.40
US$215,101
429 -4.8% 501.40 US$215,101
2026-01-20 2026-01-20 S Sale

General Counsel

Officer
263 -2.9%
490.77
US$129,073
263 -2.9% 490.77 US$129,073
2026-01-20 2026-01-20 S Sale Non-Executive Director
2,238 -0.5%
490.77
US$1,098,343
2,238 -0.5% 490.77 US$1,098,343
2026-01-13 2026-01-09 PlS Planned sale Non-Executive Director
40 -0.0%
545.79
US$21,832
40 -0.0% 545.79 US$21,832
2026-01-13 2026-01-09 PlS Planned sale Non-Executive Director
600 -0.3%
540.36
US$324,215
600 -0.3% 540.36 US$324,215
2026-01-13 2026-01-09 PlS Planned sale Non-Executive Director
480 -0.3%
539.23
US$258,831
480 -0.3% 539.23 US$258,831
2026-01-13 2026-01-09 PlS Planned sale Non-Executive Director
80 -0.0%
537.85
US$43,028
80 -0.0% 537.85 US$43,028
2026-01-13 2026-01-09 PlS Planned sale Non-Executive Director
487 -0.3%
536.88
US$261,459
487 -0.3% 536.88 US$261,459
2026-01-13 2026-01-09 PlS Planned sale Non-Executive Director
473 -0.2%
536.02
US$253,538
473 -0.2% 536.02 US$253,538
2026-01-13 2026-01-09 PlS Planned sale Non-Executive Director
148 -0.1%
535.29
US$79,223
148 -0.1% 535.29 US$79,223
2026-01-13 2026-01-09 PlS Planned sale Non-Executive Director
332 -0.2%
534.16
US$177,342
332 -0.2% 534.16 US$177,342
2026-01-13 2026-01-09 PlS Planned sale Non-Executive Director
80 -0.0%
532.50
US$42,600
80 -0.0% 532.50 US$42,600