| Jan. 12, 2021
|
Jan. 12, 2021 |
S
Sell
|
Lim Bryant David
SVP and General Counsel
Officer
|
1,711
-4.3%
4.21
7,202
USD
|
1,711
-4.3%
|
4.21
|
7,202
USD
|
|
| Jan. 12, 2021
|
Jan. 12, 2021 |
S
Sell
|
MILANO VINCENT
President & CEO
Executive Director
|
3,210
-1.5%
4.20
13,474
USD
|
3,210
-1.5%
|
4.20
|
13,474
USD
|
|
| Jan. 12, 2021
|
Jan. 12, 2021 |
S
Sell
|
Tarka Elizabeth Ann
Chief Medical Officer
Officer
|
1,745
-8.7%
4.19
7,310
USD
|
1,745
-8.7%
|
4.19
|
7,310
USD
|
|
| Jan. 12, 2021
|
Jan. 12, 2021 |
S
Sell
|
Kirby John J.
Chief Financial Officer
Officer
|
1,693
-4.8%
4.22
7,152
USD
|
1,693
-4.8%
|
4.22
|
7,152
USD
|
|
| Jan. 11, 2021
|
Jan. 5, 2021 |
S
Sell
|
Lim Bryant David
SVP and General Counsel
Officer
|
1,465
-3.6%
3.91
5,722
USD
|
1,465
-3.6%
|
3.91
|
5,722
USD
|
|
| Jan. 11, 2021
|
Jan. 5, 2021 |
S
Sell
|
MILANO VINCENT
President & CEO
Executive Director
|
2,740
-1.3%
3.91
10,700
USD
|
2,740
-1.3%
|
3.91
|
10,700
USD
|
|
| Jan. 6, 2021
|
Jan. 5, 2021 |
S
Sell
|
Kirby John J.
Chief Financial Officer
Officer
|
862
-2.4%
3.90
3,362
USD
|
862
-2.4%
|
3.90
|
3,362
USD
|
|
| Dec. 15, 2020
|
Dec. 11, 2020 |
B
Buy
|
Pillar Invest Corp
Major owner
|
69,941
+1.3%
1.82
127,293
USD
|
69,941
+1.3%
|
1.82
|
127,293
USD
|
|
| July 15, 2020
|
July 13, 2020 |
B
Buy
|
Pillar Invest Corp
Major owner
|
749,993
+16.0%
1.72
1,289,988
USD
|
749,993
+16.0%
|
1.72
|
1,289,988
USD
|
|
| April 9, 2020
|
April 7, 2020 |
B
Buy
|
Pillar Invest Corp
Major owner
|
3,039,514
+94.4%
1.52
4,620,061
USD
|
3,039,514
+94.4%
|
1.52
|
4,620,061
USD
|
|
| Feb. 26, 2020
|
Jan. 29, 2020 |
S
Sell
|
Pillar Invest Corp
Major owner
|
17,250
-0.5%
1.76
30,438
USD
|
17,250
-0.5%
|
1.76
|
30,438
USD
|
|
| Feb. 26, 2020
|
Jan. 28, 2020 |
S
Sell
|
Pillar Invest Corp
Major owner
|
12,532
-0.4%
1.76
22,081
USD
|
12,532
-0.4%
|
1.76
|
22,081
USD
|
|
| Feb. 26, 2020
|
Jan. 27, 2020 |
S
Sell
|
Pillar Invest Corp
Major owner
|
15,000
-0.5%
1.77
26,550
USD
|
15,000
-0.5%
|
1.77
|
26,550
USD
|
|
| Jan. 10, 2020
|
Jan. 7, 2020 |
S
Sell
|
Kirby John J.
Chief Financial Officer
|
911
-5.3%
1.78
1,622
USD
|
911
-5.3%
|
1.78
|
1,622
USD
|
|
| Jan. 10, 2020
|
Jan. 7, 2020 |
S
Sell
|
Fletcher Robert C.
Sr. VP, Bus. Dev. & Strategy
|
1,615
-8.9%
1.78
2,875
USD
|
1,615
-8.9%
|
1.78
|
2,875
USD
|
|
| Jan. 10, 2020
|
Jan. 7, 2020 |
S
Sell
|
MILANO VINCENT
President & CEO
Executive Director
|
3,006
-3.4%
1.78
5,352
USD
|
3,006
-3.4%
|
1.78
|
5,352
USD
|
|
| Jan. 10, 2020
|
Jan. 7, 2020 |
S
Sell
|
Lim Bryant David
SVP and General Counsel
|
1,603
-7.0%
1.78
2,854
USD
|
1,603
-7.0%
|
1.78
|
2,854
USD
|
|
| Jan. 10, 2020
|
Jan. 7, 2020 |
S
Sell
|
YINGLING JONATHAN MICHAEL
Chief Scientific Officer
|
1,742
-9.6%
1.78
3,101
USD
|
1,742
-9.6%
|
1.78
|
3,101
USD
|
|
| Nov. 8, 2019
|
Nov. 8, 2019 |
S
Sell
|
Pillar Invest Corp
Major owner
|
9,000
-0.3%
2.44
21,960
USD
|
9,000
-0.3%
|
2.44
|
21,960
USD
|
|
| Nov. 8, 2019
|
Nov. 7, 2019 |
S
Sell
|
Pillar Invest Corp
Major owner
|
10,000
-0.3%
2.45
24,500
USD
|
10,000
-0.3%
|
2.45
|
24,500
USD
|
|
| Nov. 8, 2019
|
Nov. 6, 2019 |
S
Sell
|
Pillar Invest Corp
Major owner
|
100,000
-2.9%
2.50
249,560
USD
|
100,000
-2.9%
|
2.50
|
249,560
USD
|
|
| Dec. 26, 2018
|
Dec. 24, 2018 |
B
Buy
|
MILANO VINCENT
President & CEO
Executive Director
|
15,000
+36.8%
2.93
43,923
USD
|
15,000
+36.8%
|
2.93
|
43,923
USD
|
|
| Dec. 26, 2018
|
Dec. 21, 2018 |
B
Buy
|
Lim Bryant David
SVP and General Counsel
Officer
|
4,000
+538.4%
3.05
12,200
USD
|
4,000
+538.4%
|
3.05
|
12,200
USD
|
|
| Dec. 20, 2018
|
Dec. 20, 2018 |
B
Buy
|
Horobin Joanna
Chief Medical Officer
Officer
|
300
+17.2%
3.45
1,035
USD
|
300
+17.2%
|
3.45
|
1,035
USD
|
|
| Dec. 20, 2018
|
Dec. 19, 2018 |
B
Buy
|
Goldberg Mark Alan
Non-Executive Director
|
10,000
+inf%
3.19
31,897
USD
|
10,000
+inf%
|
3.19
|
31,897
USD
|
|
| Dec. 20, 2018
|
Dec. 19, 2018 |
B
Buy
|
SCHAFER CAROL
Non-Executive Director
|
5,000
+inf%
3.33
16,671
USD
|
5,000
+inf%
|
3.33
|
16,671
USD
|
|
| Aug. 17, 2018
|
Aug. 9, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
15,000
-100.0%
6.35
95,324
USD
|
15,000
-100.0%
|
6.35
|
95,324
USD
|
|
| Aug. 17, 2018
|
Aug. 9, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
25,000
-100.0%
6.29
157,358
USD
|
25,000
-100.0%
|
6.29
|
157,358
USD
|
|
| Aug. 17, 2018
|
Aug. 9, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
15,000
-100.0%
6.25
93,762
USD
|
15,000
-100.0%
|
6.25
|
93,762
USD
|
|
| Aug. 17, 2018
|
Aug. 8, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
20,000
-100.0%
5.98
119,500
USD
|
20,000
-100.0%
|
5.98
|
119,500
USD
|
|
| Aug. 17, 2018
|
Aug. 8, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
50,000
-100.0%
5.88
294,190
USD
|
50,000
-100.0%
|
5.88
|
294,190
USD
|
|
| Aug. 17, 2018
|
Aug. 8, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
8,107
-100.0%
5.89
47,759
USD
|
8,107
-100.0%
|
5.89
|
47,759
USD
|
|
| Aug. 17, 2018
|
Aug. 7, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
75,000
-100.0%
5.62
421,718
USD
|
75,000
-100.0%
|
5.62
|
421,718
USD
|
|
| Aug. 17, 2018
|
Aug. 7, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
91,893
-100.0%
5.55
510,098
USD
|
91,893
-100.0%
|
5.55
|
510,098
USD
|
|
| Aug. 8, 2018
|
Aug. 7, 2018 |
B
Buy
|
GERAGHTY JAMES A
Non-Executive Director
|
10,000
+18.0%
5.58
55,800
USD
|
10,000
+18.0%
|
5.58
|
55,800
USD
|
|
| Aug. 8, 2018
|
Aug. 7, 2018 |
B
Buy
|
MILANO VINCENT
President & CEO
Executive Director
|
10,000
+32.5%
5.51
55,100
USD
|
10,000
+32.5%
|
5.51
|
55,100
USD
|
|
| July 24, 2018
|
July 20, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
492,567
-100.0%
0.86
422,672
USD
|
492,567
-100.0%
|
0.86
|
422,672
USD
|
|
| July 24, 2018
|
July 19, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
556,000
-100.0%
0.88
489,502
USD
|
556,000
-100.0%
|
0.88
|
489,502
USD
|
|
| July 24, 2018
|
July 18, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
1,725,000
-100.0%
0.85
1,470,390
USD
|
1,725,000
-100.0%
|
0.85
|
1,470,390
USD
|
|
| July 19, 2018
|
July 17, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
874,505
-100.0%
0.99
862,524
USD
|
874,505
-100.0%
|
0.99
|
862,524
USD
|
|
| July 19, 2018
|
July 16, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
735,771
-100.0%
1.01
743,644
USD
|
735,771
-100.0%
|
1.01
|
743,644
USD
|
|
| July 19, 2018
|
July 13, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
250,500
-100.0%
1.05
264,052
USD
|
250,500
-100.0%
|
1.05
|
264,052
USD
|
|
| Jan. 19, 2018
|
Jan. 17, 2018 |
S
Sell
|
Pillar Invest Corp
Major owner
|
200,000
-100.0%
2.40
480,000
USD
|
200,000
-100.0%
|
2.40
|
480,000
USD
|
|
| Dec. 15, 2017
|
Dec. 15, 2017 |
S
Sell
|
Pillar Invest Corp
Major owner
|
33,830
-100.0%
1.91
64,527
USD
|
33,830
-100.0%
|
1.91
|
64,527
USD
|
|
| Dec. 15, 2017
|
Dec. 14, 2017 |
S
Sell
|
Pillar Invest Corp
Major owner
|
300,000
-100.0%
2.00
599,430
USD
|
300,000
-100.0%
|
2.00
|
599,430
USD
|
|
| Dec. 15, 2017
|
Dec. 14, 2017 |
S
Sell
|
Pillar Invest Corp
Major owner
|
700,000
-100.0%
2.00
1,400,000
USD
|
700,000
-100.0%
|
2.00
|
1,400,000
USD
|
|
| Dec. 15, 2017
|
Dec. 14, 2017 |
S
Sell
|
Pillar Invest Corp
Major owner
|
166,170
-100.0%
2.01
333,171
USD
|
166,170
-100.0%
|
2.01
|
333,171
USD
|
|
| Dec. 15, 2017
|
Dec. 13, 2017 |
S
Sell
|
Pillar Invest Corp
Major owner
|
600,000
-100.0%
1.93
1,158,420
USD
|
600,000
-100.0%
|
1.93
|
1,158,420
USD
|
|
| Dec. 15, 2017
|
Dec. 13, 2017 |
S
Sell
|
Pillar Invest Corp
Major owner
|
500,000
-100.0%
1.92
959,750
USD
|
500,000
-100.0%
|
1.92
|
959,750
USD
|
|
| Oct. 30, 2017
|
Oct. 26, 2017 |
B
Buy
|
BAKER BROS. ADVISORS LP
|
7,204,652
+77.0%
1.50
10,806,978
USD
|
7,204,652
+77.0%
|
1.50
|
10,806,978
USD
|
|