|
2023-11-02 |
2023-11-02 |
B
Purchase
|
Large shareholder
|
41,565
+2.4%
242.97
US$4,036,520
|
41,565
+2.4%
|
242.97
|
US$4,036,520
|
|
|
2023-11-02 |
2023-11-01 |
B
Purchase
|
Large shareholder
|
51,213
+13.0%
384.97
US$4,506,007
|
51,213
+13.0%
|
384.97
|
US$4,506,007
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
Large shareholder
|
57,459
+17.0%
74.72
US$2,917,720
|
57,459
+17.0%
|
74.72
|
US$2,917,720
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
Large shareholder
|
11,987
+0.3%
0.26
US$3,147
|
11,987
+0.3%
|
0.26
|
US$3,147
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
Large shareholder
|
130,509
+2.5%
0.24
US$31,505
|
130,509
+2.5%
|
0.24
|
US$31,505
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
Large shareholder
|
12,345
+0.2%
0.26
US$3,228
|
12,345
+0.2%
|
0.26
|
US$3,228
|
|
|
2023-11-02 |
2023-10-31 |
B
Purchase
|
Large shareholder
|
11,987
+0.2%
0.26
US$3,147
|
11,987
+0.2%
|
0.26
|
US$3,147
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
Ex VP & Chief Commerc. Officer
Officer
|
1,875
-3.2%
1.07
US$2,008
|
1,875
-3.2%
|
1.07
|
US$2,008
|
|
|
2023-03-21 |
2023-03-17 |
S
Sale
|
Ex VP & Chief Commerc. Officer
Officer
|
2,520
-4.2%
1.07
US$2,696
|
2,520
-4.2%
|
1.07
|
US$2,696
|
|
|
2023-01-25 |
2023-01-23 |
B
Purchase
|
Non-Executive Director
|
50,000
+inf%
1.43
US$71,580
|
50,000
+inf%
|
1.43
|
US$71,580
|
|
|
2023-01-03 |
2022-12-29 |
S
Sale
|
Non-Executive Director
|
5,000
-31.2%
1.22
US$6,104
|
5,000
-31.2%
|
1.22
|
US$6,104
|
|
|
2022-12-27 |
2022-12-22 |
B
Purchase
|
Non-Executive Director
|
100,000
+121.4%
1.28
US$127,950
|
100,000
+121.4%
|
1.28
|
US$127,950
|
|
|
2022-12-27 |
2022-12-22 |
S
Sale
|
Non-Executive Director
|
22,500
-51.7%
1.17
US$26,302
|
22,500
-51.7%
|
1.17
|
US$26,302
|
|
|
2022-08-18 |
2022-08-16 |
PlS
Planned sale
|
Non-Executive Director
|
5,000
-31.2%
9.81
US$49,030
|
5,000
-31.2%
|
9.81
|
US$49,030
|
|
|
2022-03-14 |
2022-03-14 |
S
Sale
|
Ex VP & Chief Commerc. Officer
Officer
|
1,657
-2.7%
5.60
US$9,275
|
1,657
-2.7%
|
5.60
|
US$9,275
|
|
|
2022-03-14 |
2022-03-14 |
S
Sale
|
Chief Financial Officer
Officer
|
2,266
-5.2%
5.60
US$12,683
|
2,266
-5.2%
|
5.60
|
US$12,683
|
|
|
2022-01-11 |
2022-01-07 |
S
Sale
|
Ex VP & Chief Commerc. Officer
Officer
|
1,560
-3.3%
4.95
US$7,722
|
1,560
-3.3%
|
4.95
|
US$7,722
|
|
|
2021-03-15 |
2021-03-15 |
S
Sale
|
Non-Executive Director
|
2,000
-20.0%
10.14
US$20,280
|
2,000
-20.0%
|
10.14
|
US$20,280
|
|
|
2021-01-11 |
2021-01-08 |
S
Sale
|
Ex VP & Chief Commerc. Officer
Officer
|
1,690
-4.5%
11.68
US$19,739
|
1,690
-4.5%
|
11.68
|
US$19,739
|
|
|
2020-08-12 |
2020-08-12 |
B
Purchase
|
Non-Executive Director
|
4,500
+900.0%
11.44
US$51,465
|
4,500
+900.0%
|
11.44
|
US$51,465
|
|
|
2020-08-12 |
2020-08-12 |
B
Purchase
|
Non-Executive Director
|
500
+inf%
11.28
US$5,638
|
500
+inf%
|
11.28
|
US$5,638
|
|
|
2020-08-12 |
2020-08-11 |
B
Purchase
|
Non-Executive Director
|
5,000
+7.5%
11.49
US$57,464
|
5,000
+7.5%
|
11.49
|
US$57,464
|
|
|
2020-03-17 |
2020-03-16 |
B
Purchase
|
Non-Executive Director
|
30,000
+82.5%
5.03
US$150,813
|
30,000
+82.5%
|
5.03
|
US$150,813
|
|
|
2020-03-17 |
2020-03-16 |
B
Purchase
|
Non-Executive Director
|
1,000
+3.4%
4.95
US$4,950
|
1,000
+3.4%
|
4.95
|
US$4,950
|
|
|
2020-01-30 |
2020-01-24 |
B
Purchase
|
Ex VP & Chief Commerc. Officer
|
5,000
+20.0%
13.52
US$67,602
|
5,000
+20.0%
|
13.52
|
US$67,602
|
|
|
2020-01-13 |
2020-01-10 |
B
Purchase
|
|
4,000
+20.0%
13.94
US$55,760
|
4,000
+20.0%
|
13.94
|
US$55,760
|
|
|
2019-04-23 |
2019-04-23 |
B
Purchase
|
|
5,000
+33.3%
11.10
US$55,495
|
5,000
+33.3%
|
11.10
|
US$55,495
|
|
|
2019-04-22 |
2019-04-22 |
B
Purchase
|
See Remarks
|
1,000
+33.3%
11.03
US$11,030
|
1,000
+33.3%
|
11.03
|
US$11,030
|
|
|
2019-04-22 |
2019-04-22 |
B
Purchase
|
Chief Financial Officer
|
1,250
+inf%
11.08
US$13,853
|
1,250
+inf%
|
11.08
|
US$13,853
|
|
|
2019-04-22 |
2019-04-22 |
B
Purchase
|
|
5,000
+50.0%
11.05
US$55,250
|
5,000
+50.0%
|
11.05
|
US$55,250
|
|
|
2019-04-26 |
2019-02-04 |
B
Purchase
|
President and CEO
Executive Director
|
343
+0.5%
11.26
US$3,862
|
343
+0.5%
|
11.26
|
US$3,862
|
|
|
2019-02-06 |
2019-02-04 |
B
Purchase
|
President and CEO
Executive Director
|
227
+0.4%
14.13
US$3,208
|
227
+0.4%
|
14.13
|
US$3,208
|
|
|
2018-12-20 |
2018-12-20 |
B
Purchase
|
Dietz Thomas John
Non-Executive Director
|
5,000
+100.0%
9.98
US$49,900
|
5,000
+100.0%
|
9.98
|
US$49,900
|
|
|
2018-12-10 |
2018-12-06 |
B
Purchase
|
Dietz Thomas John
Non-Executive Director
|
5,000
+inf%
11.26
US$56,300
|
5,000
+inf%
|
11.26
|
US$56,300
|
|
|
2018-11-30 |
2018-11-29 |
B
Purchase
|
Mayer Eldon C. III
Non-Executive Director
|
4,000
+19.0%
10.21
US$40,840
|
4,000
+19.0%
|
10.21
|
US$40,840
|
|
|
2018-11-28 |
2018-11-27 |
B
Purchase
|
Mayer Eldon C. III
Non-Executive Director
|
7,500
+100.0%
9.92
US$74,408
|
7,500
+100.0%
|
9.92
|
US$74,408
|
|
|
2018-11-28 |
2018-11-26 |
B
Purchase
|
Mayer Eldon C. III
Non-Executive Director
|
7,500
+inf%
9.75
US$73,143
|
7,500
+inf%
|
9.75
|
US$73,143
|
|
|
2018-10-22 |
2018-10-18 |
S
Sale
|
INTERWEST PARTNERS X LP
Large shareholder
|
26,465
-1.9%
12.00
US$317,606
|
26,465
-1.9%
|
12.00
|
US$317,606
|
|
|
2018-10-22 |
2018-10-18 |
S
Sale
|
INTERWEST PARTNERS X LP
Large shareholder
|
210,800
-13.2%
12.07
US$2,544,714
|
210,800
-13.2%
|
12.07
|
US$2,544,714
|
|
|
2018-04-04 |
2018-04-02 |
S
Sale
|
Quan Joanne
Chief Medical Officer
|
4,000
-100.0%
10.00
US$40,000
|
4,000
-100.0%
|
10.00
|
US$40,000
|
|
|
2017-09-05 |
2017-09-01 |
B
Purchase
|
Glenn Jeffrey S
|
15,000
+91.7%
9.53
US$142,950
|
15,000
+91.7%
|
9.53
|
US$142,950
|
|
|
2016-11-21 |
2016-11-18 |
B
Purchase
|
Glenn Jeffrey S
Non-Executive Director
|
460
+inf%
12.90
US$5,934
|
460
+inf%
|
12.90
|
US$5,934
|
|
|
2016-11-21 |
2016-11-17 |
B
Purchase
|
Glenn Jeffrey S
Non-Executive Director
|
15,000
+1107.0%
12.73
US$190,950
|
15,000
+1107.0%
|
12.73
|
US$190,950
|
|
|
2016-08-22 |
2016-08-18 |
B
Purchase
|
Vivo Ventures VI, LLC
Large shareholder
|
1,364
+11.7%
16.00
US$21,824
|
1,364
+11.7%
|
16.00
|
US$21,824
|
|
|
2016-08-22 |
2016-08-18 |
B
Purchase
|
Vivo Ventures VI, LLC
Large shareholder
|
186,136
+11.7%
16.00
US$2,978,176
|
186,136
+11.7%
|
16.00
|
US$2,978,176
|
|
|
2016-08-19 |
2016-08-18 |
B
Purchase
|
Cory David A
President and CEO
Executive Director
|
1,562
+2.7%
15.70
US$24,523
|
1,562
+2.7%
|
15.70
|
US$24,523
|
|
|
2016-08-19 |
2016-08-18 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
3,125
+125.3%
15.70
US$49,062
|
3,125
+125.3%
|
15.70
|
US$49,062
|
|
|
2016-06-22 |
2016-06-22 |
B
Purchase
|
WELCH JAMES H
Chief Financial Officer
Officer
|
500
+25.0%
19.79
US$9,897
|
500
+25.0%
|
19.79
|
US$9,897
|
|
|
2016-06-22 |
2016-06-20 |
B
Purchase
|
WELCH JAMES H
Chief Financial Officer
Officer
|
2,000
+inf%
19.80
US$39,592
|
2,000
+inf%
|
19.80
|
US$39,592
|
|
|
2016-06-14 |
2016-06-13 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
420
+20.2%
22.20
US$9,324
|
420
+20.2%
|
22.20
|
US$9,324
|
|
|
2016-06-14 |
2016-06-13 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
100
+5.1%
22.17
US$2,217
|
100
+5.1%
|
22.17
|
US$2,217
|
|
|
2016-06-14 |
2016-06-13 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
730
+58.6%
22.16
US$16,177
|
730
+58.6%
|
22.16
|
US$16,177
|
|
|
2016-05-23 |
2016-05-23 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
745
+149.0%
19.99
US$14,893
|
745
+149.0%
|
19.99
|
US$14,893
|
|
|
2016-05-23 |
2016-05-19 |
B
Purchase
|
Shaffer James P
Chief Business Officer
Officer
|
500
+inf%
19.52
US$9,760
|
500
+inf%
|
19.52
|
US$9,760
|
|
|
2015-04-07 |
2015-04-06 |
PlS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
6,629
-68.0%
18.44
US$122,239
|
6,629
-68.0%
|
18.44
|
US$122,239
|
|
|
2015-04-07 |
2015-04-06 |
PlS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
41,302
-80.9%
18.16
US$750,044
|
41,302
-80.9%
|
18.16
|
US$750,044
|
|
|
2015-04-03 |
2015-04-02 |
PlS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
1,012
-25.9%
16.95
US$17,153
|
1,012
-25.9%
|
16.95
|
US$17,153
|
|
|
2015-04-03 |
2015-04-02 |
PlS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
10,000
-71.9%
17.33
US$173,300
|
10,000
-71.9%
|
17.33
|
US$173,300
|
|
|
2015-04-03 |
2015-04-01 |
PlS
Planned sale
|
TAKEYA RYAN K
VP, Manufacturing
Officer
|
4,444
-75.6%
19.13
US$85,014
|
4,444
-75.6%
|
19.13
|
US$85,014
|
|
|
2015-03-09 |
2015-03-09 |
PlS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
6,629
-68.0%
24.71
US$163,803
|
6,629
-68.0%
|
24.71
|
US$163,803
|
|
|
2015-03-09 |
2015-03-09 |
PlS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
41,302
-80.9%
24.81
US$1,024,703
|
41,302
-80.9%
|
24.81
|
US$1,024,703
|
|
|
2015-03-09 |
2015-03-06 |
PlS
Planned sale
|
Honig Peter
Non-Executive Director
|
5,000
-100.0%
25.00
US$125,000
|
5,000
-100.0%
|
25.00
|
US$125,000
|
|
|
2015-03-09 |
2015-03-06 |
PlS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
4,000
-58.0%
22.48
US$89,920
|
4,000
-58.0%
|
22.48
|
US$89,920
|
|
|
2015-03-09 |
2015-03-06 |
PlS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
10,000
-59.2%
23.29
US$232,900
|
10,000
-59.2%
|
23.29
|
US$232,900
|
|
|
2015-03-09 |
2015-03-05 |
PlS
Planned sale
|
Honig Peter
Non-Executive Director
|
2,200
-100.0%
22.29
US$49,038
|
2,200
-100.0%
|
22.29
|
US$49,038
|
|
|
2015-03-09 |
2015-03-05 |
PlS
Planned sale
|
Honig Peter
Non-Executive Director
|
2,500
-53.2%
22.50
US$56,250
|
2,500
-53.2%
|
22.50
|
US$56,250
|
|
|
2015-03-03 |
2015-03-02 |
PlS
Planned sale
|
TAKEYA RYAN K
VP, Manufacturing
Officer
|
7,777
-84.4%
18.48
US$143,719
|
7,777
-84.4%
|
18.48
|
US$143,719
|
|
|
2015-02-10 |
2015-02-09 |
PlS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
6,629
-68.0%
15.94
US$105,666
|
6,629
-68.0%
|
15.94
|
US$105,666
|
|
|
2015-02-10 |
2015-02-09 |
PlS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
41,302
-80.9%
15.85
US$654,637
|
41,302
-80.9%
|
15.85
|
US$654,637
|
|
|
2015-02-10 |
2015-02-06 |
PlS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
4,000
-58.0%
16.08
US$64,320
|
4,000
-58.0%
|
16.08
|
US$64,320
|
|
|
2015-02-10 |
2015-02-06 |
PlS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
10,000
-59.2%
16.08
US$160,800
|
10,000
-59.2%
|
16.08
|
US$160,800
|
|
|
2015-02-03 |
2015-02-02 |
PlS
Planned sale
|
TAKEYA RYAN K
VP, Manufacturing
Officer
|
7,777
-84.4%
16.35
US$127,154
|
7,777
-84.4%
|
16.35
|
US$127,154
|
|
|
2015-01-12 |
2015-01-09 |
PlS
Planned sale
|
RUDY JEFFREY J
VP, Clinical Operations
Officer
|
10,000
-90.7%
18.51
US$185,100
|
10,000
-90.7%
|
18.51
|
US$185,100
|
|
|
2015-01-08 |
2015-01-07 |
PlS
Planned sale
|
LABA REBECQUE J
VP, Corporate Operations
Officer
|
20,000
-87.4%
17.30
US$346,000
|
20,000
-87.4%
|
17.30
|
US$346,000
|
|
|
2015-01-08 |
2015-01-06 |
PlS
Planned sale
|
ZSEBO KRISZTINA M
Chief Executive Officer
Executive Director
|
41,302
-93.0%
17.51
US$723,198
|
41,302
-93.0%
|
17.51
|
US$723,198
|
|