|
2019-02-01 |
2019-01-30 |
PS
Planned sale
|
AYRES JOHN C
SEE REMARKS
Officer
|
3,125
-2.3%
4.19
USD 13,094
|
3,125
-2.3%
|
4.19
|
USD 13,094
|
|
|
2018-12-17 |
2018-12-17 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
46,094
-8.2%
5.85
USD 269,788
|
46,094
-8.2%
|
5.85
|
USD 269,788
|
|
|
2018-11-09 |
2018-11-07 |
PS
Planned sale
|
HEINEN ERNST
Chief Development Officer
Officer
|
19,308
-12.5%
6.95
USD 134,191
|
19,308
-12.5%
|
6.95
|
USD 134,191
|
|
|
2018-11-06 |
2018-11-02 |
PS
Planned sale
|
HEINEN ERNST
Chief Development Officer
Officer
|
692
-0.4%
6.95
USD 4,809
|
692
-0.4%
|
6.95
|
USD 4,809
|
|
|
2018-10-31 |
2018-10-30 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
11,513
-2.0%
5.86
USD 67,454
|
11,513
-2.0%
|
5.86
|
USD 67,454
|
|
|
2018-09-21 |
2018-09-21 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
75,000
-11.6%
6.06
USD 454,305
|
75,000
-11.6%
|
6.06
|
USD 454,305
|
|
|
2018-08-14 |
2018-08-14 |
PS
Planned sale
|
HEINEN ERNST
Chief Development Officer
Officer
|
1,712
-1.1%
5.15
USD 8,817
|
1,712
-1.1%
|
5.15
|
USD 8,817
|
|
|
2018-08-14 |
2018-08-13 |
PS
Planned sale
|
HEINEN ERNST
Chief Development Officer
Officer
|
8,660
-5.2%
5.15
USD 44,599
|
8,660
-5.2%
|
5.15
|
USD 44,599
|
|
|
2018-08-10 |
2018-08-10 |
PS
Planned sale
|
HEINEN ERNST
Chief Development Officer
Officer
|
1,954
-1.2%
5.15
USD 10,063
|
1,954
-1.2%
|
5.15
|
USD 10,063
|
|
|
2018-08-10 |
2018-08-08 |
PS
Planned sale
|
HEINEN ERNST
Chief Development Officer
Officer
|
2,674
-1.6%
5.15
USD 13,771
|
2,674
-1.6%
|
5.15
|
USD 13,771
|
|
|
2018-07-30 |
2018-07-30 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
11,513
-1.7%
4.33
USD 49,842
|
11,513
-1.7%
|
4.33
|
USD 49,842
|
|
|
2018-06-27 |
2018-06-25 |
PS
Planned sale
|
Standridge Brent
Chief Operating Officer
Officer
|
10,000
-9.1%
4.56
USD 45,644
|
10,000
-9.1%
|
4.56
|
USD 45,644
|
|
|
2018-02-01 |
2018-01-30 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
19,367
-2.8%
4.77
USD 92,301
|
19,367
-2.8%
|
4.77
|
USD 92,301
|
|
|
2018-01-12 |
2018-01-11 |
PS
Planned sale
|
TOOMAN CRAIG A
CHIEF FINANCIAL OFFICER
Officer
|
30,000
-28.6%
5.27
USD 158,040
|
30,000
-28.6%
|
5.27
|
USD 158,040
|
|
|
2017-12-01 |
2017-12-01 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
425,298
-9.0%
5.40
USD 2,296,609
|
425,298
-9.0%
|
5.40
|
USD 2,296,609
|
|
|
2017-12-01 |
2017-12-01 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
1,900
-0.0%
5.44
USD 10,336
|
1,900
-0.0%
|
5.44
|
USD 10,336
|
|
|
2017-12-01 |
2017-12-01 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
50,000
-1.0%
5.45
USD 272,500
|
50,000
-1.0%
|
5.45
|
USD 272,500
|
|
|
2017-12-01 |
2017-12-01 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
100
-0.0%
5.47
USD 547
|
100
-0.0%
|
5.47
|
USD 547
|
|
|
2017-12-01 |
2017-12-01 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
5,110
-0.1%
5.52
USD 28,207
|
5,110
-0.1%
|
5.52
|
USD 28,207
|
|
|
2017-12-01 |
2017-12-01 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
8,020
-0.2%
5.53
USD 44,351
|
8,020
-0.2%
|
5.53
|
USD 44,351
|
|
|
2017-12-01 |
2017-12-01 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
72,000
-1.5%
5.65
USD 406,800
|
72,000
-1.5%
|
5.65
|
USD 406,800
|
|
|
2017-12-01 |
2017-11-30 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
50,000
-1.0%
5.90
USD 295,000
|
50,000
-1.0%
|
5.90
|
USD 295,000
|
|
|
2017-12-01 |
2017-11-30 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
50,000
-1.0%
5.95
USD 297,500
|
50,000
-1.0%
|
5.95
|
USD 297,500
|
|
|
2017-12-01 |
2017-11-30 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
100,000
-2.0%
5.95
USD 595,000
|
100,000
-2.0%
|
5.95
|
USD 595,000
|
|
|
2017-12-01 |
2017-11-30 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
11,472
-0.2%
5.97
USD 68,488
|
11,472
-0.2%
|
5.97
|
USD 68,488
|
|
|
2017-12-01 |
2017-11-30 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
100
-0.0%
6.03
USD 603
|
100
-0.0%
|
6.03
|
USD 603
|
|
|
2017-12-01 |
2017-11-29 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
1,900
-0.0%
6.26
USD 11,894
|
1,900
-0.0%
|
6.26
|
USD 11,894
|
|
|
2017-12-01 |
2017-11-29 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
300
-0.0%
6.28
USD 1,884
|
300
-0.0%
|
6.28
|
USD 1,884
|
|
|
2017-12-01 |
2017-11-29 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
7,700
-0.2%
6.35
USD 48,895
|
7,700
-0.2%
|
6.35
|
USD 48,895
|
|
|
2017-12-01 |
2017-11-29 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
50,000
-1.0%
6.50
USD 325,000
|
50,000
-1.0%
|
6.50
|
USD 325,000
|
|
|
2017-12-01 |
2017-11-29 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
5,751
-0.1%
6.55
USD 37,669
|
5,751
-0.1%
|
6.55
|
USD 37,669
|
|
|
2017-12-01 |
2017-11-29 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
49,865
-1.0%
6.60
USD 329,109
|
49,865
-1.0%
|
6.60
|
USD 329,109
|
|
|
2017-12-01 |
2017-11-29 |
S
Sale
|
Broadfin Healthcare Master Fund Ltd
Large shareholder
|
1,000
-0.0%
6.66
USD 6,660
|
1,000
-0.0%
|
6.66
|
USD 6,660
|
|
|
2017-11-13 |
2017-11-10 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
50,000
-8.6%
7.00
USD 350,000
|
50,000
-8.6%
|
7.00
|
USD 350,000
|
|
|
2017-10-04 |
2017-10-02 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
50,000
-7.9%
6.24
USD 312,115
|
50,000
-7.9%
|
6.24
|
USD 312,115
|
|
|
2017-09-27 |
2017-09-25 |
PS
Planned sale
|
Standridge Brent
Chief Operating Officer
|
10,000
-12.5%
6.11
USD 61,127
|
10,000
-12.5%
|
6.11
|
USD 61,127
|
|
|
2017-09-19 |
2017-09-15 |
PS
Planned sale
|
HEINEN ERNST
Chief Development Officer
|
10,000
-7.1%
6.25
USD 62,500
|
10,000
-7.1%
|
6.25
|
USD 62,500
|
|
|
2017-04-18 |
2017-04-17 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
50,000
-7.9%
5.54
USD 277,150
|
50,000
-7.9%
|
5.54
|
USD 277,150
|
|
|
2017-01-31 |
2017-01-27 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
50,000
-7.3%
7.72
USD 385,875
|
50,000
-7.3%
|
7.72
|
USD 385,875
|
|
|
2016-12-16 |
2016-12-15 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
50,000
-8.4%
7.63
USD 381,380
|
50,000
-8.4%
|
7.63
|
USD 381,380
|
|
|
2016-10-04 |
2016-10-03 |
PS
Planned sale
|
HEINEN ERNST
Chief Development Officer
Officer
|
10,000
-8.0%
10.00
USD 100,006
|
10,000
-8.0%
|
10.00
|
USD 100,006
|
|
|
2016-09-12 |
2016-09-09 |
PS
Planned sale
|
TOOMAN CRAIG A
CHIEF FINANCIAL OFFICER
Officer
|
30,000
-29.3%
9.25
USD 277,599
|
30,000
-29.3%
|
9.25
|
USD 277,599
|
|
|
2016-08-10 |
2016-08-09 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
50,000
-7.2%
9.25
USD 462,500
|
50,000
-7.2%
|
9.25
|
USD 462,500
|
|
|
2016-06-28 |
2016-06-28 |
PS
Planned sale
|
STEPHANUS JULIA A
CHIEF COMMERCIAL OFFICER
Officer
|
30,000
-19.0%
6.25
USD 187,500
|
30,000
-19.0%
|
6.25
|
USD 187,500
|
|
|
2016-06-17 |
2016-06-17 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
25,000
-3.5%
6.32
USD 158,020
|
25,000
-3.5%
|
6.32
|
USD 158,020
|
|
|
2016-06-17 |
2016-06-16 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
75,000
-9.5%
6.24
USD 468,293
|
75,000
-9.5%
|
6.24
|
USD 468,293
|
|
|
2016-06-13 |
2016-06-10 |
PS
Planned sale
|
HEINEN ERNST
Chief Development Officer
Officer
|
15,000
-10.7%
6.72
USD 100,862
|
15,000
-10.7%
|
6.72
|
USD 100,862
|
|
|
2016-02-02 |
2016-02-01 |
PS
Planned sale
|
TOOMAN CRAIG A
CHIEF FINANCIAL OFFICER
Officer
|
2,806
-2.7%
3.36
USD 9,436
|
2,806
-2.7%
|
3.36
|
USD 9,436
|
|
|
2015-04-28 |
2015-04-27 |
PS
Planned sale
|
Rhodes Linda
CHIEF SCIENTIFIC OFFICER
Officer
|
3,300
-0.8%
15.78
USD 52,073
|
3,300
-0.8%
|
15.78
|
USD 52,073
|
|
|
2015-04-28 |
2015-04-27 |
PS
Planned sale
|
Rhodes Linda
CHIEF SCIENTIFIC OFFICER
Officer
|
11,700
-2.7%
14.78
USD 172,912
|
11,700
-2.7%
|
14.78
|
USD 172,912
|
|
|
2015-01-06 |
2015-01-02 |
PS
Planned sale
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
25,000
-3.5%
17.87
USD 446,648
|
25,000
-3.5%
|
17.87
|
USD 446,648
|
|
|
2014-03-12 |
2014-03-10 |
S
Sale
|
MPM BIOVENTURES V, L.P.
Large shareholder
|
600,000
-17.9%
20.02
USD 12,012,000
|
600,000
-17.9%
|
20.02
|
USD 12,012,000
|
|
|
2014-03-11 |
2014-03-07 |
S
Sale
|
Foley Todd
Large shareholder
|
12,539
-100.0%
19.95
USD 250,153
|
12,539
-100.0%
|
19.95
|
USD 250,153
|
|
|
2014-03-11 |
2014-03-07 |
S
Sale
|
GADICKE ANSBERT
Large shareholder
|
26,713
-100.0%
20.16
USD 538,534
|
26,713
-100.0%
|
20.16
|
USD 538,534
|
|
|
2014-02-05 |
2014-02-03 |
S
Sale
|
MEEUSEN RONALD L
Non-Executive Director
|
45,100
-37.4%
19.00
USD 856,900
|
45,100
-37.4%
|
19.00
|
USD 856,900
|
|
|
2014-02-05 |
2014-02-03 |
S
Sale
|
MEEUSEN RONALD L
Non-Executive Director
|
454,900
-37.4%
19.00
USD 8,643,100
|
454,900
-37.4%
|
19.00
|
USD 8,643,100
|
|
|
2014-02-05 |
2014-02-03 |
S
Sale
|
Avalon Ventures IX, L.P.
Large shareholder
|
825,000
-19.8%
19.00
USD 15,675,000
|
825,000
-19.8%
|
19.00
|
USD 15,675,000
|
|
|
2014-02-05 |
2014-02-03 |
S
Sale
|
Lichter Jay
Non-Executive Director
Large shareholder
|
825,000
-19.8%
19.00
USD 15,675,000
|
825,000
-19.8%
|
19.00
|
USD 15,675,000
|
|
|
2013-07-03 |
2013-07-02 |
B
Purchase
|
St Peter Steven
PRESIDENT AND CEO
Executive Director
|
8,333
+1.6%
6.00
USD 49,998
|
8,333
+1.6%
|
6.00
|
USD 49,998
|
|
|
2013-07-03 |
2013-07-02 |
B
Purchase
|
STEPHANUS JULIA A
CHIEF COMMERCIAL OFFICER
Officer
|
2,000
+1.5%
6.00
USD 12,000
|
2,000
+1.5%
|
6.00
|
USD 12,000
|
|
|
2013-07-02 |
2013-07-02 |
B
Purchase
|
Vander Vort John
Non-Executive Director
Large shareholder
|
500,000
+13.0%
6.00
USD 3,000,000
|
500,000
+13.0%
|
6.00
|
USD 3,000,000
|
|
|
2013-07-02 |
2013-07-02 |
B
Purchase
|
MPM BIOVENTURES V, L.P.
Large shareholder
|
500,000
+13.0%
6.00
USD 3,000,000
|
500,000
+13.0%
|
6.00
|
USD 3,000,000
|
|
