|
2018-09-20 |
2018-09-19 |
S
Sale
|
Froehlich Juergen Kurt
Chief Medical Officer
Officer
|
306
-0.3%
1.20
USD 367
|
306
-0.3%
|
1.20
|
USD 367
|
|
|
2018-01-31 |
2018-01-29 |
S
Sale
|
Froehlich Juergen Kurt
Chief Medical Officer
Officer
|
17,011
-15.8%
1.53
USD 26,027
|
17,011
-15.8%
|
1.53
|
USD 26,027
|
|
|
2017-04-06 |
2017-04-04 |
PS
Planned sale
|
Froehlich Juergen Kurt
Chief Medical Officer
|
3,765
-4.2%
1.51
USD 5,685
|
3,765
-4.2%
|
1.51
|
USD 5,685
|
|
|
2016-10-05 |
2016-10-04 |
PS
Planned sale
|
Froehlich Juergen Kurt
Chief Medical Officer
Officer
|
423
-0.5%
6.76
USD 2,859
|
423
-0.5%
|
6.76
|
USD 2,859
|
|
|
2016-06-23 |
2016-06-21 |
PS
Planned sale
|
Froehlich Juergen Kurt
Chief Medical Officer
Officer
|
333
-0.4%
4.45
USD 1,482
|
333
-0.4%
|
4.45
|
USD 1,482
|
|
|
2013-12-16 |
2013-12-13 |
S
Sale
|
THOMPSON VIRGIL
Non-Executive Director
|
3,340
-0.3%
0.17
USD 568
|
3,340
-0.3%
|
0.17
|
USD 568
|
|
|
2013-08-29 |
2013-08-27 |
B
Purchase
|
First Eagle Investment Management, LLC
Large shareholder
|
40,322,580
0.12
USD 5,000,000
|
40,322,580
|
0.12
|
USD 5,000,000
|
|
|
2012-12-13 |
2012-12-11 |
B
Purchase
|
First Eagle Investment Management, LLC
Large shareholder
|
41,666,667
+57.6%
0.12
USD 5,000,000
|
41,666,667
+57.6%
|
0.12
|
USD 5,000,000
|
|
|
2011-07-11 |
2011-07-07 |
B
Purchase
|
First Eagle Value in Biotechnology Master Fund, Ltd.
See Footnote below
Large shareholder
|
10,625,000
+17.5%
0.19
USD 2,018,750
|
10,625,000
+17.5%
|
0.19
|
USD 2,018,750
|
|
|
2010-11-09 |
2010-11-05 |
S
Sale
|
NOVO NORDISK A S
Large shareholder
|
401,469
-1.5%
0.17
USD 68,691
|
401,469
-1.5%
|
0.17
|
USD 68,691
|
|
|
2010-11-05 |
2010-11-04 |
S
Sale
|
NOVO NORDISK A S
Large shareholder
|
225,000
-0.8%
0.17
USD 38,183
|
225,000
-0.8%
|
0.17
|
USD 38,183
|
|
|
2010-11-04 |
2010-11-03 |
S
Sale
|
NOVO NORDISK A S
Large shareholder
|
250,000
-0.9%
0.16
USD 40,750
|
250,000
-0.9%
|
0.16
|
USD 40,750
|
|
|
2010-11-03 |
2010-11-02 |
S
Sale
|
NOVO NORDISK A S
Large shareholder
|
256,675
-0.9%
0.16
USD 42,249
|
256,675
-0.9%
|
0.16
|
USD 42,249
|
|
|
2010-11-02 |
2010-11-01 |
S
Sale
|
NOVO NORDISK A S
Large shareholder
|
236,406
-0.9%
0.17
USD 39,031
|
236,406
-0.9%
|
0.17
|
USD 39,031
|
|
|
2010-06-22 |
2010-06-18 |
B
Purchase
|
First Eagle Value in Biotechnology Master Fund, Ltd.
See Remarks.
Large shareholder
|
19,433,408
+52.4%
0.12
USD 2,300,916
|
19,433,408
+52.4%
|
0.12
|
USD 2,300,916
|
|
|
2008-10-31 |
2008-10-29 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
5,600,000
-83.8%
0.25
USD 1,400,000
|
5,600,000
-83.8%
|
0.25
|
USD 1,400,000
|
|
|
2008-10-23 |
2008-10-21 |
B
Purchase
|
TANG KEVIN C
Large shareholder
|
10,000
+0.2%
0.24
USD 2,400
|
10,000
+0.2%
|
0.24
|
USD 2,400
|
|
|
2008-10-22 |
2008-10-20 |
B
Purchase
|
TANG KEVIN C
Large shareholder
|
17,000
+0.3%
0.24
USD 4,080
|
17,000
+0.3%
|
0.24
|
USD 4,080
|
|
|
2008-10-15 |
2008-10-13 |
B
Purchase
|
TANG KEVIN C
Large shareholder
|
25,000
+0.5%
0.24
USD 6,000
|
25,000
+0.5%
|
0.24
|
USD 6,000
|
|
|
2008-10-14 |
2008-10-10 |
B
Purchase
|
TANG KEVIN C
Large shareholder
|
45,000
+0.8%
0.24
USD 10,602
|
45,000
+0.8%
|
0.24
|
USD 10,602
|
|
