BAKER BROS CAPITAL GP LLC

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2004-05-07	2004-05-05	Ardea Biosciences Inc (RDEA)	B Purchase	46,895 +16.3% 24.93 US$2,788,836	46,895 +16.3%	24.93	US$2,788,836