Joice Judy R

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2021-05-17	2021-05-14	DURECT Corp (DRRX)	PlS Planned sale	68,821 -22.6% 115.33 US$4,759,027	68,821 -22.6%	115.33	US$4,759,027
2020-06-05	2020-06-03	DURECT Corp (DRRX)	PlS Planned sale	69,061 -41.6% 182.48 US$3,762,829	69,061 -41.6%	182.48	US$3,762,829
2020-06-05	2020-06-03	DURECT Corp (DRRX)	PlS Planned sale	76,961 +2.1% 400.43 US$4,452,715	76,961 +2.1%	400.43	US$4,452,715