GILL SIMBA

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2023-11-08	2023-11-08	Evelo Biosciences Inc (EVLO)	PlS Planned sale	76,801 +31.5% 14.56 US$2,391,040	76,801 +31.5%	14.56	US$2,391,040
2023-09-29	2023-09-28	Evelo Biosciences Inc (EVLO)	PlS Planned sale	86,390 -2.9% 204.45 US$979,109	86,390 -2.9%	204.45	US$979,109
2023-08-09	2023-08-08	Evelo Biosciences Inc (EVLO)	PlS Planned sale	88,599 +33.0% 352.31 US$2,334,250	88,599 +33.0%	352.31	US$2,334,250
2023-05-10	2023-05-08	Evelo Biosciences Inc (EVLO)	PlS Planned sale	3,537 -5.7% 0.13 US$444	3,537 -5.7%	0.13	US$444