Thomas Dolca

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2022-09-06	2022-09-02	Aduro Biotech Inc (ADRO)	B Purchase	55,976 -32.2% 231.17 US$1,734,974	55,976 -32.2%	231.17	US$1,734,974
2022-09-06	2022-09-02	Aduro Biotech Inc (ADRO)	B Purchase	29,491 -14.3% 333.69 US$4,545,305	29,491 -14.3%	333.69	US$4,545,305
2020-08-20	2020-08-18	Principia Biopharma Inc (PRNB)	PlS Planned sale	57,155 -16.2% 220.60 US$4,864,688	57,155 -16.2%	220.60	US$4,864,688
2020-07-17	2020-07-15	Principia Biopharma Inc (PRNB)	PlS Planned sale	15,000 -89.1% 80.07 US$1,201,070	15,000 -89.1%	80.07	US$1,201,070