SMITH IAN F

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2016-05-18	2016-05-16	Vertex Pharmaceuticals Inc (VRTX)	PlS Planned sale	62,155 +41.0% 343.99 US$3,870,105	62,155 +41.0%	343.99	US$3,870,105
2016-01-06	2016-01-04	Acorda Therapeutics Inc (ACOR)	PlS Planned sale	7,744 +25.1% 13.02 US$4,743,908	7,744 +25.1%	13.02	US$4,743,908
2016-01-06	2016-01-04	Acorda Therapeutics Inc (ACOR)	PlS Planned sale	73,105 +13.4% 477.97 US$4,030,542	73,105 +13.4%	477.97	US$4,030,542