Oliveira Orlando

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2018-09-05	2018-09-04	TESARO Inc (TSRO)	PlS Planned sale	21,257 +0.6% 370.71 US$1,980,861	21,257 +0.6%	370.71	US$1,980,861
2018-03-05	2018-03-02	TESARO Inc (TSRO)	PlS Planned sale	21,685 -18.6% 418.07 US$4,459,719	21,685 -18.6%	418.07	US$4,459,719
2017-09-06	2017-09-05	TESARO Inc (TSRO)	S Sale	42,195 -6.3% 135.99 US$1,623,651	42,195 -6.3%	135.99	US$1,623,651