Brian Rosenberger

Currently holds a position at Zynerba Pharmaceuticals Inc

Position	Company	Period
Vice President - commercial and business development	Zynerba Pharmaceuticals Inc	Jan. 1, 2017 -
Vice President - Manufacturing	Zynerba Pharmaceuticals Inc	Sept. 14, 2015 - Jan. 1, 2017

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2023-09-14	2023-09-13	Zynerba Pharmaceuticals Inc (ZYNE)	S Sale	22,515 +42.5% 14.14 US$4,184,064	22,515 +42.5%	14.14	US$4,184,064
2023-01-25	2023-01-23	Zynerba Pharmaceuticals Inc (ZYNE)	S Sale	31,765 +28.6% 319.37 US$1,751,315	31,765 +28.6%	319.37	US$1,751,315
2022-07-20	2022-07-19	Zynerba Pharmaceuticals Inc (ZYNE)	S Sale	1,398 +40.5% 207.76 US$2,765,986	1,398 +40.5%	207.76	US$2,765,986