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United States Biotechnology & Medical Research

Spruce Biosciences Inc (SPRB)

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Ticker: SPRB Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
Parkman Healthcare Partners LLC
2 buys, 4 sells — total 19,011 USD
Sale 6 Oct 2025
Value US$2,460,500.86 | Price 452.50 | Shares 96,881
Sale 6 Oct 2025
Value US$2,196,654.30 | Price 108.43 | Shares 47,862
Buy 6 Oct 2025
Value US$4,585.16 | Price 17.91 | Shares 256
Sale 6 Oct 2025
Value US$436.39 | Price 17.46 | Shares 25
Sale 6 Oct 2025
Value US$4,483.72 | Price 19.33 | Shares 232
Buy 6 Oct 2025
Value US$4,585.16 | Price 17.91 | Shares 256
Sale 21 Mar 2024
Value US$64,417.31 | Price 287.60 | Shares 67,325
Sale 20 Mar 2024
Value US$264,080.59 | Price 0.73 | Shares 359,979
Sale 19 Mar 2024
Value US$447,715.00 | Price 0.76 | Shares 593,000
Sale 18 Mar 2024
Value US$647,008.17 | Price 0.77 | Shares 842,020
Proposed sale 18 Mar 2024
Value US$3,899,002.21 | Price 0.81 | Shares 4,810,020
Sale 14 Mar 2024
Value US$1,698,901.53 | Price 0.89 | Shares 1,912,316
Proposed sale 14 Mar 2024
Value US$9,485,087.36 | Price 4.96 | Shares 1,912,316
Buy 16 Feb 2023
Value US$1,998,368.00 | Price 3.17 | Shares 630,400
Buy 16 Feb 2023
Value US$6,999,360.00 | Price 3.17 | Shares 2,208,000
Planned sale 20 May 2021
Value US$5,106.86 | Price 15.29 | Shares 334
Sale 19 May 2021
Value US$6,602,500.00 | Price 13.90 | Shares 475,000
Planned sale 30 Apr 2021
Value US$226,663.83 | Price 16.14 | Shares 14,045
Buy 14 Oct 2020
Value US$3,000,000.00 | Price 15.00 | Shares 200,000
Buy 14 Oct 2020
Value US$3,750,000.00 | Price 15.00 | Shares 250,000
Buy 14 Oct 2020
Value US$3,750,000.00 | Price 15.00 | Shares 250,000
Buy 14 Oct 2020
Value US$3,750,000.00 | Price 15.00 | Shares 250,000
Buy 14 Oct 2020
Value US$3,750,000.00 | Price 15.00 | Shares 250,000
Buy 14 Oct 2020
Value US$3,750,000.00 | Price 15.00 | Shares 250,000
Buy 14 Oct 2020
Value US$3,750,000.00 | Price 15.00 | Shares 250,000
Buy 14 Oct 2020
Value US$3,750,000.00 | Price 15.00 | Shares 250,000
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2025-10-15 2025-10-06 S Sale
Parkman Healthcare Partners LLC
Large shareholder
96,881 -47.3%
452.50
US$2,460,501 		96,881 -47.3% 452.50 US$2,460,501
2025-10-15 2025-10-06 S Sale
Parkman Healthcare Partners LLC
Large shareholder
47,862 +3.7%
108.43
US$2,196,654 		47,862 +3.7% 108.43 US$2,196,654
2025-10-15 2025-10-06 B Purchase
Parkman Healthcare Partners LLC
Large shareholder
77,762 -38.8%
293.76
US$4,118,734 		77,762 -38.8% 293.76 US$4,118,734
2025-10-08 2025-10-06 S Sale
Parkman Healthcare Partners LLC
Large shareholder
25 -2.3%
17.46
US$436 		25 -2.3% 17.46 US$436
2025-10-08 2025-10-06 S Sale
Parkman Healthcare Partners LLC
Large shareholder
232 -17.8%
19.33
US$4,484 		232 -17.8% 19.33 US$4,484
2025-10-08 2025-10-06 B Purchase
Parkman Healthcare Partners LLC
Large shareholder
256 +24.4%
17.91
US$4,585 		256 +24.4% 17.91 US$4,585
2024-03-25 2024-03-21 S Sale
2.3
Novo Holdings A/S
Large shareholder
465,021 -15.4%
0.75
US$350,951 		465,021 -15.4% 0.75 US$350,951
2024-03-20 2024-03-20 S Sale
2.3
Novo Holdings A/S
Large shareholder
359,979 -10.7%
0.73
US$264,081 		359,979 -10.7% 0.73 US$264,081
2024-03-20 2024-03-19 S Sale
2.3
Novo Holdings A/S
Large shareholder
593,000 -14.9%
0.76
US$447,715 		593,000 -14.9% 0.76 US$447,715
2024-03-20 2024-03-18 S Sale
2.3
Novo Holdings A/S
Large shareholder
842,020 -17.5%
0.77
US$647,008 		842,020 -17.5% 0.77 US$647,008
2024-03-18 2024-03-18 PrS Proposed sale
2.3
Novo Holdings A/S

10% Stockholder

Large shareholder
4,810,020
0.81
US$3,899,002 		4,810,020 0.81 US$3,899,002
2024-03-18 2024-03-14 S Sale
2.3
Novo Holdings A/S
Large shareholder
1,912,316 -28.4%
0.89
US$1,698,902 		1,912,316 -28.4% 0.89 US$1,698,902
2024-03-14 2024-03-14 PrS Proposed sale
2.3
Novo Holdings A/S

10% Stockholder

Large shareholder
1,912,316
4.96
US$9,485,087 		1,912,316 4.96 US$9,485,087
2023-05-16 2023-02-16 B Purchase
1.8
O'Donnell Niall
Non-Executive Director
630,400 +90.6%
3.17
US$1,998,368 		630,400 +90.6% 3.17 US$1,998,368
2023-02-21 2023-02-16 B Purchase
2.3
Novo Holdings A/S
Large shareholder
2,208,000 +48.9%
3.17
US$6,999,360 		2,208,000 +48.9% 3.17 US$6,999,360
2021-05-21 2021-05-20 PlS Planned sale
SIMPSON CAMILLA V
Non-Executive Director
334 -100.0%
15.29
US$5,107 		334 -100.0% 15.29 US$5,107
2021-05-21 2021-05-19 S Sale
2.3
Novo Holdings A/S
Large shareholder
475,000 -9.5%
13.90
US$6,602,500 		475,000 -9.5% 13.90 US$6,602,500
2021-05-04 2021-04-30 PlS Planned sale
SIMPSON CAMILLA V
Non-Executive Director
14,045 -100.0%
16.14
US$226,664 		14,045 -100.0% 16.14 US$226,664
2020-10-16 2020-10-14 B Purchase
1.5
Muralidhar Bali
Non-Executive Director
200,000 +12.6%
15.00
US$3,000,000 		200,000 +12.6% 15.00 US$3,000,000
2020-10-16 2020-10-14 B Purchase
HANSSON JONAS
Non-Executive Director
250,000 +14.0%
15.00
US$3,750,000 		250,000 +14.0% 15.00 US$3,750,000
2020-10-16 2020-10-14 B Purchase
HealthCap VIII, L.P.

Former 10% Owner
250,000 +14.0%
15.00
US$3,750,000 		250,000 +14.0% 15.00 US$3,750,000
2020-10-16 2020-10-14 B Purchase
2.3
Novo Holdings A/S
Large shareholder
250,000 +5.3%
15.00
US$3,750,000 		250,000 +5.3% 15.00 US$3,750,000
2020-10-16 2020-10-14 B Purchase
1.3
RiverVest Venture Fund III, L.P.
Large shareholder
250,000 +13.2%
15.00
US$3,750,000 		250,000 +13.2% 15.00 US$3,750,000
2020-10-16 2020-10-14 B Purchase
3.3
Omega Fund VI, L.P.

Former 10% Owner
250,000 +13.1%
15.00
US$3,750,000 		250,000 +13.1% 15.00 US$3,750,000
2020-10-16 2020-10-14 B Purchase
1.8
O'Donnell Niall
Non-Executive Director
250,000 +56.1%
15.00
US$3,750,000 		250,000 +56.1% 15.00 US$3,750,000
2020-10-16 2020-10-14 B Purchase
Chaya Moghrabi Dina
Non-Executive Director
250,000 +13.1%
15.00
US$3,750,000 		250,000 +13.1% 15.00 US$3,750,000
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