|
2022-04-07 |
2022-04-06 |
PlS
Planned sale
|
Chief Reg & Tech Ops Officer
Officer
|
94,849
-47.9%
202.09
US$191,322
|
94,849
-47.9%
|
202.09
|
US$191,322
|
|
|
2022-04-07 |
2022-04-05 |
PlS
Planned sale
|
Chief Reg & Tech Ops Officer
Officer
|
65,851
-40.0%
308.09
US$3,554,653
|
65,851
-40.0%
|
308.09
|
US$3,554,653
|
|
|
2022-04-04 |
2022-04-04 |
PlS
Planned sale
|
General Counsel, CCO & Sec'y
Officer
|
32,399
-23.9%
123.96
US$948,251
|
32,399
-23.9%
|
123.96
|
US$948,251
|
|
|
2022-03-22 |
2022-03-18 |
PlS
Planned sale
|
Chief Reg & Tech Ops Officer
Officer
|
100
-100.0%
37.05
US$3,705
|
100
-100.0%
|
37.05
|
US$3,705
|
|
|
2022-03-17 |
2022-03-17 |
PlS
Planned sale
|
Chief Reg & Tech Ops Officer
Officer
|
3,453
-100.0%
37.06
US$127,954
|
3,453
-100.0%
|
37.06
|
US$127,954
|
|
|
2022-03-04 |
2022-03-04 |
PlS
Planned sale
|
General Counsel, CCO & Sec'y
Officer
|
2,000
-100.0%
30.60
US$61,196
|
2,000
-100.0%
|
30.60
|
US$61,196
|
|
|
2022-02-08 |
2022-02-07 |
PlS
Planned sale
|
Chief Reg & Tech Ops Officer
Officer
|
10,000
-100.0%
32.32
US$323,225
|
10,000
-100.0%
|
32.32
|
US$323,225
|
|
|
2022-02-04 |
2022-02-04 |
PlS
Planned sale
|
General Counsel, CCO & Sec'y
Officer
|
2,000
-100.0%
29.78
US$59,560
|
2,000
-100.0%
|
29.78
|
US$59,560
|
|
|
2022-02-02 |
2022-02-02 |
B
Purchase
|
Large shareholder
|
175,000
+inf%
27.00
US$4,725,000
|
175,000
+inf%
|
27.00
|
US$4,725,000
|
|
|
2022-02-02 |
2022-02-02 |
B
Purchase
|
Non-Executive Director
Large shareholder
|
175,000
+inf%
27.00
US$4,725,000
|
175,000
+inf%
|
27.00
|
US$4,725,000
|
|
|
2022-02-01 |
2022-01-31 |
B
Purchase
|
Non-Executive Director
|
150,000
+12.9%
27.00
US$4,050,000
|
150,000
+12.9%
|
27.00
|
US$4,050,000
|
|
|
2022-02-01 |
2022-01-31 |
B
Purchase
|
Large shareholder
|
150,000
+12.9%
27.00
US$4,050,000
|
150,000
+12.9%
|
27.00
|
US$4,050,000
|
|
|
2022-01-31 |
2022-01-31 |
B
Purchase
|
Non-Executive Director
Large shareholder
|
800,000
+41.3%
27.00
US$21,600,000
|
800,000
+41.3%
|
27.00
|
US$21,600,000
|
|
|
2022-01-31 |
2022-01-31 |
B
Purchase
|
Large shareholder
|
800,000
+41.3%
27.00
US$21,600,000
|
800,000
+41.3%
|
27.00
|
US$21,600,000
|
|
|
2022-01-28 |
2022-01-26 |
PlS
Planned sale
|
Chief Reg & Tech Ops Officer
Officer
|
5,000
-100.0%
27.05
US$135,250
|
5,000
-100.0%
|
27.05
|
US$135,250
|
|
|
2022-01-28 |
2022-01-26 |
PlS
Planned sale
|
General Counsel & Secretary
Officer
|
2,000
-100.0%
29.00
US$58,000
|
2,000
-100.0%
|
29.00
|
US$58,000
|
|
|
2021-11-24 |
2021-11-24 |
B
Purchase
|
Non-Executive Director
|
7,899
+141.0%
23.09
US$182,348
|
7,899
+141.0%
|
23.09
|
US$182,348
|
|
|
2021-11-24 |
2021-11-23 |
B
Purchase
|
Non-Executive Director
|
5,601
+inf%
22.95
US$128,515
|
5,601
+inf%
|
22.95
|
US$128,515
|
|
|
2021-05-20 |
2021-05-19 |
B
Purchase
|
CEO and President
Executive Director
|
5,000
+inf%
17.83
US$89,150
|
5,000
+inf%
|
17.83
|
US$89,150
|
|
|
2020-08-18 |
2020-08-18 |
B
Purchase
|
Chief Development Officer
Officer
|
3,325
+198.5%
12.25
US$40,738
|
3,325
+198.5%
|
12.25
|
US$40,738
|
|
|
2020-08-18 |
2020-08-18 |
B
Purchase
|
Chief Development Officer
Officer
|
5,950
+146.9%
12.22
US$72,710
|
5,950
+146.9%
|
12.22
|
US$72,710
|
|
|
2019-08-26 |
2019-08-23 |
B
Purchase
|
Klencke Barbara
Chief Development Officer
Officer
|
108,000
+200.0%
0.44
US$47,380
|
108,000
+200.0%
|
0.44
|
US$47,380
|
|
|
2019-08-26 |
2019-08-22 |
B
Purchase
|
Klencke Barbara
Chief Development Officer
Officer
|
54,000
+inf%
0.45
US$24,295
|
54,000
+inf%
|
0.45
|
US$24,295
|
|
|
2019-08-26 |
2019-08-22 |
B
Purchase
|
Klencke Barbara
Chief Development Officer
Officer
|
67,000
+inf%
0.43
US$28,964
|
67,000
+inf%
|
0.43
|
US$28,964
|
|
|
2018-12-11 |
2018-12-10 |
B
Purchase
|
Allen Andrew R
Non-Executive Director
|
66,000
+inf%
1.64
US$108,240
|
66,000
+inf%
|
1.64
|
US$108,240
|
|
|
2017-03-09 |
2017-03-08 |
B
Purchase
|
You Angie
Chief Bus. & Strat. Officer
|
30,000
+29.1%
1.43
US$42,900
|
30,000
+29.1%
|
1.43
|
US$42,900
|
|
|
2017-02-16 |
2017-02-14 |
B
Purchase
|
Topper James N
Large shareholder
|
5,925,926
+inf%
1.35
US$8,000,000
|
5,925,926
+inf%
|
1.35
|
US$8,000,000
|
|
|
2016-03-24 |
2016-03-22 |
PlS
Planned sale
|
Chapman Wendy
SVP Clinical Operations
Officer
|
3,000
-100.0%
7.01
US$21,023
|
3,000
-100.0%
|
7.01
|
US$21,023
|
|
|
2016-02-24 |
2016-02-22 |
PlS
Planned sale
|
Chapman Wendy
SVP Clinical Operations
Officer
|
3,000
-100.0%
7.06
US$21,180
|
3,000
-100.0%
|
7.06
|
US$21,180
|
|
|
2016-01-25 |
2016-01-22 |
PlS
Planned sale
|
Chapman Wendy
SVP Clinical Operations
Officer
|
5,000
-100.0%
9.39
US$46,973
|
5,000
-100.0%
|
9.39
|
US$46,973
|
|
|
2016-01-22 |
2016-01-22 |
PlS
Planned sale
|
Rodigueza Wendi
Chief Scientific Officer
Officer
|
1,000
-0.6%
9.66
US$9,660
|
1,000
-0.6%
|
9.66
|
US$9,660
|
|
|
2016-01-22 |
2016-01-21 |
PlS
Planned sale
|
Rodigueza Wendi
Chief Scientific Officer
Officer
|
1,000
-0.6%
10.32
US$10,323
|
1,000
-0.6%
|
10.32
|
US$10,323
|
|
|
2016-01-22 |
2016-01-20 |
PlS
Planned sale
|
Rodigueza Wendi
Chief Scientific Officer
Officer
|
1,000
-0.6%
9.59
US$9,590
|
1,000
-0.6%
|
9.59
|
US$9,590
|
|
|
2016-01-19 |
2016-01-15 |
PlS
Planned sale
|
Glover Nicholas
CEO and President
Executive Director
|
5,000
-100.0%
10.04
US$50,223
|
5,000
-100.0%
|
10.04
|
US$50,223
|
|
|
2016-01-14 |
2016-01-12 |
PlS
Planned sale
|
Lovejoy Chandra D
SVP of Reg. Affairs & Quality
Officer
|
5,562
-100.0%
11.93
US$66,345
|
5,562
-100.0%
|
11.93
|
US$66,345
|
|
|
2016-01-14 |
2016-01-12 |
PlS
Planned sale
|
Lovejoy Chandra D
SVP of Reg. Affairs & Quality
Officer
|
15,411
-73.5%
11.06
US$170,489
|
15,411
-73.5%
|
11.06
|
US$170,489
|
|
|
2015-07-21 |
2015-07-21 |
B
Purchase
|
CHA ALBERT
Non-Executive Director
|
4,693
+0.2%
17.00
US$79,781
|
4,693
+0.2%
|
17.00
|
US$79,781
|
|
|
2015-07-21 |
2015-07-21 |
B
Purchase
|
CHA ALBERT
Non-Executive Director
|
215,307
+9.7%
17.00
US$3,660,219
|
215,307
+9.7%
|
17.00
|
US$3,660,219
|
|
|
2015-07-21 |
2015-07-21 |
B
Purchase
|
ORBIMED ADVISORS LLC
Non-Executive Director
|
175,000
+9.6%
17.00
US$2,975,000
|
175,000
+9.6%
|
17.00
|
US$2,975,000
|
|
|
2015-07-21 |
2015-07-21 |
B
Purchase
|
Topper James N
Non-Executive Director
|
220,000
+11.2%
17.00
US$3,740,000
|
220,000
+11.2%
|
17.00
|
US$3,740,000
|
|
|
2015-07-21 |
2015-07-21 |
B
Purchase
|
VIVO VENTURES VII, LLC
Former 10% holder
|
4,693
+0.2%
17.00
US$79,781
|
4,693
+0.2%
|
17.00
|
US$79,781
|
|
|
2015-07-21 |
2015-07-21 |
B
Purchase
|
VIVO VENTURES VII, LLC
Former 10% holder
|
215,307
+9.7%
17.00
US$3,660,219
|
215,307
+9.7%
|
17.00
|
US$3,660,219
|
|
|
2015-07-21 |
2015-07-21 |
B
Purchase
|
Thompson Peter A.
Non-Executive Director
|
175,000
+9.6%
17.00
US$2,975,000
|
175,000
+9.6%
|
17.00
|
US$2,975,000
|
|