Thomson Mary Christina

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2022-04-04	2022-04-04	Sierra Oncology Inc (SRRA)	PlS Planned sale	32,399 -23.9% 123.96 US$948,251	32,399 -23.9%	123.96	US$948,251
2022-03-04	2022-03-04	Sierra Oncology Inc (SRRA)	PlS Planned sale	84,171 +16.7% 69.87 US$1,167,518	84,171 +16.7%	69.87	US$1,167,518
2022-02-04	2022-02-04	Sierra Oncology Inc (SRRA)	PlS Planned sale	35,865 -31.2% 270.66 US$1,590,240	35,865 -31.2%	270.66	US$1,590,240
2022-01-28	2022-01-26	Sierra Oncology Inc (SRRA)	PlS Planned sale	2,000 -100.0% 29.00 US$58,000	2,000 -100.0%	29.00	US$58,000