|
2008-08-18 |
2008-08-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-3.1%
2.98
USD 2,327
|
781
-3.1%
|
2.98
|
USD 2,327
|
|
|
2008-08-06 |
2008-08-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-3.0%
2.96
USD 2,312
|
781
-3.0%
|
2.96
|
USD 2,312
|
|
|
2008-07-16 |
2008-07-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
100
-0.4%
3.06
USD 306
|
100
-0.4%
|
3.06
|
USD 306
|
|
|
2008-07-16 |
2008-07-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
681
-2.8%
3.05
USD 2,077
|
681
-2.8%
|
3.05
|
USD 2,077
|
|
|
2008-07-11 |
2008-07-11 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
7,000
+0.1%
3.07
USD 21,489
|
7,000
+0.1%
|
3.07
|
USD 21,489
|
|
|
2008-07-11 |
2008-07-11 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
2,000
+0.0%
3.07
USD 6,140
|
2,000
+0.0%
|
3.07
|
USD 6,140
|
|
|
2008-07-11 |
2008-07-11 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
3,500
+0.1%
3.07
USD 10,744
|
3,500
+0.1%
|
3.07
|
USD 10,744
|
|
|
2008-07-11 |
2008-07-10 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
236,000
+4.5%
3.03
USD 715,033
|
236,000
+4.5%
|
3.03
|
USD 715,033
|
|
|
2008-07-11 |
2008-07-10 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
68,000
+1.3%
3.03
USD 206,026
|
68,000
+1.3%
|
3.03
|
USD 206,026
|
|
|
2008-07-11 |
2008-07-10 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
99,200
+1.9%
3.03
USD 300,556
|
99,200
+1.9%
|
3.03
|
USD 300,556
|
|
|
2008-07-11 |
2008-07-09 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
468,000
+10.1%
3.04
USD 1,423,422
|
468,000
+10.1%
|
3.04
|
USD 1,423,422
|
|
|
2008-07-11 |
2008-07-09 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
135,000
+3.0%
3.04
USD 410,603
|
135,000
+3.0%
|
3.04
|
USD 410,603
|
|
|
2008-07-11 |
2008-07-09 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
197,300
+4.6%
3.04
USD 600,088
|
197,300
+4.6%
|
3.04
|
USD 600,088
|
|
|
2008-07-11 |
2008-07-08 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
48,000
+1.1%
2.99
USD 143,707
|
48,000
+1.1%
|
2.99
|
USD 143,707
|
|
|
2008-07-11 |
2008-07-08 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
14,000
+0.3%
2.99
USD 41,915
|
14,000
+0.3%
|
2.99
|
USD 41,915
|
|
|
2008-07-11 |
2008-07-08 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
20,100
+0.5%
2.99
USD 60,177
|
20,100
+0.5%
|
2.99
|
USD 60,177
|
|
|
2008-07-07 |
2008-07-07 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-3.1%
1.60
USD 1,250
|
781
-3.1%
|
1.60
|
USD 1,250
|
|
|
2008-06-20 |
2008-06-18 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
644,000
+18.1%
1.45
USD 933,800
|
644,000
+18.1%
|
1.45
|
USD 933,800
|
|
|
2008-06-20 |
2008-06-18 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
187,000
+5.5%
1.45
USD 271,150
|
187,000
+5.5%
|
1.45
|
USD 271,150
|
|
|
2008-06-20 |
2008-06-18 |
B
Purchase
|
BVF PARTNERS L P/IL
Indirect Beneficial Owner
Large shareholder
|
274,257
+8.8%
1.45
USD 397,673
|
274,257
+8.8%
|
1.45
|
USD 397,673
|
|
|
2008-06-17 |
2008-06-16 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-3.3%
1.65
USD 1,289
|
781
-3.3%
|
1.65
|
USD 1,289
|
|
|
2008-06-06 |
2008-06-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-3.2%
1.35
USD 1,054
|
781
-3.2%
|
1.35
|
USD 1,054
|
|
|
2008-05-15 |
2008-05-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-3.4%
1.45
USD 1,132
|
781
-3.4%
|
1.45
|
USD 1,132
|
|
|
2008-05-06 |
2008-05-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-3.3%
1.43
USD 1,117
|
781
-3.3%
|
1.43
|
USD 1,117
|
|
|
2008-04-16 |
2008-04-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
481
-2.2%
1.19
USD 572
|
481
-2.2%
|
1.19
|
USD 572
|
|
|
2008-04-16 |
2008-04-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
300
-1.4%
1.19
USD 357
|
300
-1.4%
|
1.19
|
USD 357
|
|
|
2008-04-08 |
2008-04-07 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
281
-1.3%
1.30
USD 365
|
281
-1.3%
|
1.30
|
USD 365
|
|
|
2008-04-08 |
2008-04-07 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
200
-0.9%
1.34
USD 268
|
200
-0.9%
|
1.34
|
USD 268
|
|
|
2008-04-08 |
2008-04-07 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
200
-0.9%
1.36
USD 272
|
200
-0.9%
|
1.36
|
USD 272
|
|
|
2008-04-08 |
2008-04-07 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
100
-0.4%
1.37
USD 137
|
100
-0.4%
|
1.37
|
USD 137
|
|
|
2008-03-18 |
2008-03-17 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-3.7%
4.01
USD 3,132
|
781
-3.7%
|
4.01
|
USD 3,132
|
|
|
2008-03-05 |
2008-03-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-3.6%
4.05
USD 3,163
|
781
-3.6%
|
4.05
|
USD 3,163
|
|
|
2008-02-19 |
2008-02-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-3.8%
4.05
USD 3,163
|
781
-3.8%
|
4.05
|
USD 3,163
|
|
|
2008-02-05 |
2008-02-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-3.7%
4.40
USD 3,436
|
781
-3.7%
|
4.40
|
USD 3,436
|
|
|
2008-01-16 |
2008-01-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-4.0%
4.44
USD 3,468
|
781
-4.0%
|
4.44
|
USD 3,468
|
|
|
2008-01-07 |
2008-01-07 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-3.8%
5.15
USD 4,022
|
781
-3.8%
|
5.15
|
USD 4,022
|
|
|
2007-12-18 |
2007-12-17 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-4.2%
4.75
USD 3,710
|
781
-4.2%
|
4.75
|
USD 3,710
|
|
|
2007-12-05 |
2007-12-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-4.0%
4.85
USD 3,788
|
781
-4.0%
|
4.85
|
USD 3,788
|
|
|
2007-11-16 |
2007-11-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-4.3%
5.10
USD 3,983
|
781
-4.3%
|
5.10
|
USD 3,983
|
|
|
2007-11-05 |
2007-11-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-4.2%
6.50
USD 5,077
|
781
-4.2%
|
6.50
|
USD 5,077
|
|
|
2007-10-15 |
2007-10-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
400
-2.4%
6.43
USD 2,572
|
400
-2.4%
|
6.43
|
USD 2,572
|
|
|
2007-10-15 |
2007-10-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
200
-1.2%
6.42
USD 1,284
|
200
-1.2%
|
6.42
|
USD 1,284
|
|
|
2007-10-15 |
2007-10-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
181
-1.1%
6.41
USD 1,160
|
181
-1.1%
|
6.41
|
USD 1,160
|
|
|
2007-10-05 |
2007-10-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-4.3%
6.20
USD 4,842
|
781
-4.3%
|
6.20
|
USD 4,842
|
|
|
2007-09-17 |
2007-09-17 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-4.8%
6.20
USD 4,842
|
781
-4.8%
|
6.20
|
USD 4,842
|
|
|
2007-09-05 |
2007-09-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
21
-0.1%
6.10
USD 128
|
21
-0.1%
|
6.10
|
USD 128
|
|
|
2007-09-05 |
2007-09-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
200
-1.2%
6.10
USD 1,220
|
200
-1.2%
|
6.10
|
USD 1,220
|
|
|
2007-09-05 |
2007-09-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
560
-3.3%
6.20
USD 3,472
|
560
-3.3%
|
6.20
|
USD 3,472
|
|
|
2007-08-16 |
2007-08-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
112
-0.7%
6.45
USD 722
|
112
-0.7%
|
6.45
|
USD 722
|
|
|
2007-08-16 |
2007-08-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
669
-4.3%
6.40
USD 4,282
|
669
-4.3%
|
6.40
|
USD 4,282
|
|
|
2007-08-07 |
2007-08-06 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
181
-1.1%
6.56
USD 1,187
|
181
-1.1%
|
6.56
|
USD 1,187
|
|
|
2007-08-07 |
2007-08-06 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
600
-3.7%
6.70
USD 4,020
|
600
-3.7%
|
6.70
|
USD 4,020
|
|
|
2007-07-16 |
2007-07-16 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-5.3%
6.05
USD 4,725
|
781
-5.3%
|
6.05
|
USD 4,725
|
|
|
2007-07-09 |
2007-07-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-5.0%
5.33
USD 4,163
|
781
-5.0%
|
5.33
|
USD 4,163
|
|
|
2007-06-19 |
2007-06-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
100
-0.7%
5.18
USD 518
|
100
-0.7%
|
5.18
|
USD 518
|
|
|
2007-06-19 |
2007-06-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
100
-0.7%
5.15
USD 515
|
100
-0.7%
|
5.15
|
USD 515
|
|
|
2007-06-19 |
2007-06-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
581
-4.1%
5.11
USD 2,969
|
581
-4.1%
|
5.11
|
USD 2,969
|
|
|
2007-06-05 |
2007-06-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-5.3%
5.30
USD 4,139
|
781
-5.3%
|
5.30
|
USD 4,139
|
|
|
2007-05-16 |
2007-05-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
200
-1.6%
5.20
USD 1,040
|
200
-1.6%
|
5.20
|
USD 1,040
|
|
|
2007-05-16 |
2007-05-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
100
-0.8%
5.19
USD 519
|
100
-0.8%
|
5.19
|
USD 519
|
|
|
2007-05-16 |
2007-05-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
100
-0.8%
5.18
USD 518
|
100
-0.8%
|
5.18
|
USD 518
|
|
|
2007-05-16 |
2007-05-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
381
-2.9%
5.17
USD 1,970
|
381
-2.9%
|
5.17
|
USD 1,970
|
|
|
2007-05-08 |
2007-05-07 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
281
-2.1%
5.08
USD 1,427
|
281
-2.1%
|
5.08
|
USD 1,427
|
|
|
2007-05-08 |
2007-05-07 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
500
-3.6%
5.00
USD 2,500
|
500
-3.6%
|
5.00
|
USD 2,500
|
|
|
2007-04-17 |
2007-04-16 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
202
-1.7%
5.04
USD 1,018
|
202
-1.7%
|
5.04
|
USD 1,018
|
|
|
2007-04-17 |
2007-04-16 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
200
-1.7%
5.02
USD 1,004
|
200
-1.7%
|
5.02
|
USD 1,004
|
|
|
2007-04-17 |
2007-04-16 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
379
-3.0%
5.01
USD 1,899
|
379
-3.0%
|
5.01
|
USD 1,899
|
|
|
2007-04-05 |
2007-04-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-5.9%
4.61
USD 3,600
|
781
-5.9%
|
4.61
|
USD 3,600
|
|
|
2007-03-15 |
2007-03-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
100
-0.9%
5.53
USD 553
|
100
-0.9%
|
5.53
|
USD 553
|
|
|
2007-03-15 |
2007-03-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
681
-5.8%
5.53
USD 3,766
|
681
-5.8%
|
5.53
|
USD 3,766
|
|
|
2007-03-05 |
2007-03-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-6.2%
4.83
USD 3,772
|
781
-6.2%
|
4.83
|
USD 3,772
|
|
|
2007-02-15 |
2007-02-15 |
PS
Planned sale
|
Reich Siegfried
VP, Drug Discovery
Officer
|
781
-7.1%
5.36
USD 4,186
|
781
-7.1%
|
5.36
|
USD 4,186
|
|
|
2007-02-05 |
2007-02-05 |
PS
Planned sale
|
Myers W Todd
CFO
Officer
|
781
-6.7%
3.90
USD 3,046
|
781
-6.7%
|
3.90
|
USD 3,046
|
|
|
2007-01-16 |
2007-01-16 |
PS
Planned sale
|
Reich Siegfried
Vice President, Drug Discovery
Officer
|
9,375
-50.0%
3.50
USD 32,813
|
9,375
-50.0%
|
3.50
|
USD 32,813
|
|
|
2007-01-08 |
2007-01-05 |
PS
Planned sale
|
Myers W Todd
Chief Financial Officer
Officer
|
150
-1.5%
3.25
USD 488
|
150
-1.5%
|
3.25
|
USD 488
|
|
