|
2010-06-29 |
2010-06-28 |
S
Sale
|
WHEELER KURT
Large shareholder
|
30,954
+32.5%
390.83
US$2,438,590
|
30,954
+32.5%
|
390.83
|
US$2,438,590
|
|
|
2010-06-29 |
2010-06-28 |
S
Sale
|
MPM BIOVENTURES II QP LP
Large shareholder
|
55,424
+6.2%
23.46
US$3,998,839
|
55,424
+6.2%
|
23.46
|
US$3,998,839
|
|
|
2010-06-29 |
2010-06-25 |
S
Sale
|
WHEELER KURT
Large shareholder
|
97,162
+7.6%
280.85
US$4,585,450
|
97,162
+7.6%
|
280.85
|
US$4,585,450
|
|
|
2010-06-29 |
2010-06-25 |
S
Sale
|
MPM BIOVENTURES II QP LP
Large shareholder
|
161,293
-7.4%
10.97
US$1,769,384
|
161,293
-7.4%
|
10.97
|
US$1,769,384
|
|
|
2010-04-28 |
2010-04-27 |
S
Sale
|
MPM BIOVENTURES II QP LP
Large shareholder
|
13,900
-0.6%
10.09
US$140,251
|
13,900
-0.6%
|
10.09
|
US$140,251
|
|
|
2010-04-28 |
2010-04-27 |
S
Sale
|
WHEELER KURT
Large shareholder
|
13,900
-0.6%
10.09
US$140,251
|
13,900
-0.6%
|
10.09
|
US$140,251
|
|
|
2010-04-28 |
2010-04-26 |
S
Sale
|
MPM BIOVENTURES II QP LP
Large shareholder
|
1,000
-0.0%
10.05
US$10,050
|
1,000
-0.0%
|
10.05
|
US$10,050
|
|
|
2010-04-28 |
2010-04-26 |
S
Sale
|
WHEELER KURT
Large shareholder
|
1,000
-0.0%
10.05
US$10,050
|
1,000
-0.0%
|
10.05
|
US$10,050
|
|
|
2010-04-26 |
2010-04-23 |
S
Sale
|
WHEELER KURT
Large shareholder
|
1,900
-0.1%
10.07
US$19,133
|
1,900
-0.1%
|
10.07
|
US$19,133
|
|
|
2010-04-26 |
2010-04-23 |
S
Sale
|
MPM BIOVENTURES II QP LP
Large shareholder
|
1,900
-0.1%
10.07
US$19,133
|
1,900
-0.1%
|
10.07
|
US$19,133
|
|
|
2010-04-26 |
2010-04-22 |
S
Sale
|
WHEELER KURT
Large shareholder
|
31,811
-1.4%
10.06
US$320,019
|
31,811
-1.4%
|
10.06
|
US$320,019
|
|
|
2010-04-26 |
2010-04-22 |
S
Sale
|
MPM BIOVENTURES II QP LP
Large shareholder
|
31,811
-1.4%
10.06
US$320,019
|
31,811
-1.4%
|
10.06
|
US$320,019
|
|
|
2009-08-14 |
2009-08-12 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
1,000
+2.9%
4.30
US$4,300
|
1,000
+2.9%
|
4.30
|
US$4,300
|
|
|
2009-08-13 |
2009-08-11 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
2,000
+6.1%
4.20
US$8,400
|
2,000
+6.1%
|
4.20
|
US$8,400
|
|
|
2009-08-13 |
2009-08-10 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
2,000
+6.5%
4.15
US$8,300
|
2,000
+6.5%
|
4.15
|
US$8,300
|
|
|
2009-08-10 |
2009-08-07 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
1,200
+4.0%
4.00
US$4,800
|
1,200
+4.0%
|
4.00
|
US$4,800
|
|
|
2009-08-10 |
2009-08-07 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
2,420
+8.8%
4.05
US$9,801
|
2,420
+8.8%
|
4.05
|
US$9,801
|
|
|
2009-08-10 |
2009-08-07 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
80
+0.3%
3.99
US$319
|
80
+0.3%
|
3.99
|
US$319
|
|
|
2009-08-10 |
2009-08-07 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
300
+1.1%
4.00
US$1,200
|
300
+1.1%
|
4.00
|
US$1,200
|
|
|
2009-05-26 |
2009-05-22 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
2,000
+8.0%
3.38
US$6,760
|
2,000
+8.0%
|
3.38
|
US$6,760
|
|
|
2009-05-21 |
2009-05-21 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
2,000
+8.7%
3.39
US$6,780
|
2,000
+8.7%
|
3.39
|
US$6,780
|
|
|
2009-05-21 |
2009-05-20 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
1,100
+5.0%
3.40
US$3,740
|
1,100
+5.0%
|
3.40
|
US$3,740
|
|
|
2009-05-21 |
2009-05-20 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
100
+0.5%
3.37
US$337
|
100
+0.5%
|
3.37
|
US$337
|
|
|
2009-05-21 |
2009-05-20 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
100
+0.5%
3.34
US$334
|
100
+0.5%
|
3.34
|
US$334
|
|
|
2009-05-21 |
2009-05-20 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
600
+2.8%
3.09
US$1,854
|
600
+2.8%
|
3.09
|
US$1,854
|
|
|
2009-05-21 |
2009-05-20 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
100
+0.5%
3.08
US$308
|
100
+0.5%
|
3.08
|
US$308
|
|
|
2009-05-20 |
2009-05-19 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
912
+4.5%
3.09
US$2,818
|
912
+4.5%
|
3.09
|
US$2,818
|
|
|
2009-05-20 |
2009-05-19 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
200
+1.0%
3.08
US$616
|
200
+1.0%
|
3.08
|
US$616
|
|
|
2009-05-20 |
2009-05-19 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
100
+0.5%
3.07
US$307
|
100
+0.5%
|
3.07
|
US$307
|
|
|
2009-05-20 |
2009-05-19 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
788
+4.1%
3.00
US$2,364
|
788
+4.1%
|
3.00
|
US$2,364
|
|
|
2009-05-20 |
2009-05-18 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
1,300
+7.3%
2.99
US$3,887
|
1,300
+7.3%
|
2.99
|
US$3,887
|
|
|
2009-05-20 |
2009-05-18 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
100
+0.6%
2.98
US$298
|
100
+0.6%
|
2.98
|
US$298
|
|
|
2009-05-20 |
2009-05-18 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
100
+0.6%
2.97
US$297
|
100
+0.6%
|
2.97
|
US$297
|
|
|
2009-05-20 |
2009-05-18 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
500
+2.9%
2.96
US$1,480
|
500
+2.9%
|
2.96
|
US$1,480
|
|
|
2009-05-18 |
2009-05-15 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
1,600
+8.7%
2.99
US$4,784
|
1,600
+8.7%
|
2.99
|
US$4,784
|
|
|
2009-05-18 |
2009-05-15 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
400
+2.2%
2.98
US$1,193
|
400
+2.2%
|
2.98
|
US$1,193
|
|
|
2009-05-18 |
2009-05-15 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
500
+2.8%
2.98
US$1,490
|
500
+2.8%
|
2.98
|
US$1,490
|
|
|
2009-05-18 |
2009-05-15 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
500
+2.9%
2.97
US$1,485
|
500
+2.9%
|
2.97
|
US$1,485
|
|
|
2009-05-18 |
2009-05-14 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
166
+1.0%
2.97
US$493
|
166
+1.0%
|
2.97
|
US$493
|
|
|
2009-05-18 |
2009-05-14 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
700
+4.3%
2.96
US$2,072
|
700
+4.3%
|
2.96
|
US$2,072
|
|
|
2009-05-18 |
2009-05-14 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
834
+5.4%
2.95
US$2,460
|
834
+5.4%
|
2.95
|
US$2,460
|
|
|
2009-05-18 |
2009-05-14 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
200
+1.3%
2.92
US$584
|
200
+1.3%
|
2.92
|
US$584
|
|
|
2009-05-18 |
2009-05-14 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
100
+0.7%
2.91
US$291
|
100
+0.7%
|
2.91
|
US$291
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
CAPPS VICKIE L
Non-Executive Director
|
8,800
+141.9%
3.00
US$26,400
|
8,800
+141.9%
|
3.00
|
US$26,400
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
100
+0.3%
2.80
US$280
|
100
+0.3%
|
2.80
|
US$280
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
500
+1.4%
2.76
US$1,380
|
500
+1.4%
|
2.76
|
US$1,380
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
2,700
+8.2%
2.76
US$7,438
|
2,700
+8.2%
|
2.76
|
US$7,438
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
500
+1.5%
2.75
US$1,375
|
500
+1.5%
|
2.75
|
US$1,375
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
CAPPS VICKIE L
Non-Executive Director
|
1,200
+24.0%
2.85
US$3,420
|
1,200
+24.0%
|
2.85
|
US$3,420
|
|
|
2009-03-02 |
2009-02-26 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
1,300
+4.2%
2.73
US$3,549
|
1,300
+4.2%
|
2.73
|
US$3,549
|
|
|
2009-02-27 |
2009-02-25 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
6,000
+54.5%
2.65
US$15,900
|
6,000
+54.5%
|
2.65
|
US$15,900
|
|
|
2009-02-27 |
2009-02-25 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
3,900
+54.9%
2.64
US$10,296
|
3,900
+54.9%
|
2.64
|
US$10,296
|
|
|
2009-02-27 |
2009-02-25 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
100
+1.4%
2.62
US$262
|
100
+1.4%
|
2.62
|
US$262
|
|
|
2008-12-01 |
2008-11-28 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
900
+3.0%
2.80
US$2,520
|
900
+3.0%
|
2.80
|
US$2,520
|
|
|
2008-12-01 |
2008-11-28 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
500
+1.7%
2.75
US$1,375
|
500
+1.7%
|
2.75
|
US$1,375
|
|
|
2008-12-01 |
2008-11-28 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
200
+0.7%
2.71
US$542
|
200
+0.7%
|
2.71
|
US$542
|
|
|
2008-12-01 |
2008-11-28 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
300
+1.0%
2.66
US$798
|
300
+1.0%
|
2.66
|
US$798
|
|
|
2008-12-01 |
2008-11-26 |
B
Purchase
|
ERB JOHN L
Non-Executive Director
|
5,600
+127.3%
3.00
US$16,800
|
5,600
+127.3%
|
3.00
|
US$16,800
|
|
|
2008-12-01 |
2008-11-26 |
B
Purchase
|
ERB JOHN L
Non-Executive Director
|
400
+10.0%
2.95
US$1,180
|
400
+10.0%
|
2.95
|
US$1,180
|
|
|
2008-12-01 |
2008-11-26 |
B
Purchase
|
ERB JOHN L
Non-Executive Director
|
200
+5.3%
2.86
US$572
|
200
+5.3%
|
2.86
|
US$572
|
|
|
2008-12-01 |
2008-11-26 |
B
Purchase
|
ERB JOHN L
Non-Executive Director
|
100
+2.7%
2.69
US$269
|
100
+2.7%
|
2.69
|
US$269
|
|
|
2008-12-01 |
2008-11-26 |
B
Purchase
|
ERB JOHN L
Non-Executive Director
|
2,200
+146.7%
2.68
US$5,896
|
2,200
+146.7%
|
2.68
|
US$5,896
|
|
|
2008-12-01 |
2008-11-26 |
B
Purchase
|
ERB JOHN L
Non-Executive Director
|
1,000
+200.0%
2.50
US$2,500
|
1,000
+200.0%
|
2.50
|
US$2,500
|
|
|
2008-12-01 |
2008-11-26 |
B
Purchase
|
ERB JOHN L
Non-Executive Director
|
500
+inf%
2.47
US$1,235
|
500
+inf%
|
2.47
|
US$1,235
|
|
|
2008-11-25 |
2008-11-25 |
B
Purchase
|
BENDER A THOMAS
Non-Executive Director
|
2,000
+40.0%
2.25
US$4,500
|
2,000
+40.0%
|
2.25
|
US$4,500
|
|
|
2008-02-27 |
2008-02-26 |
S
Sale
|
TREU JESSE I
Non-Executive Director
|
2,750
-11.1%
8.43
US$23,182
|
2,750
-11.1%
|
8.43
|
US$23,182
|
|
|
2008-02-26 |
2008-02-25 |
B
Purchase
|
CAPPS VICKIE L
Non-Executive Director
|
4,700
+1566.7%
8.60
US$40,420
|
4,700
+1566.7%
|
8.60
|
US$40,420
|
|
|
2008-02-26 |
2008-02-25 |
B
Purchase
|
CAPPS VICKIE L
Non-Executive Director
|
200
+200.0%
8.57
US$1,714
|
200
+200.0%
|
8.57
|
US$1,714
|
|
|
2008-02-26 |
2008-02-25 |
B
Purchase
|
CAPPS VICKIE L
Non-Executive Director
|
100
+inf%
8.56
US$856
|
100
+inf%
|
8.56
|
US$856
|
|
|
2007-11-21 |
2007-11-20 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
1,200
+10.8%
9.11
US$10,930
|
1,200
+10.8%
|
9.11
|
US$10,930
|
|
|
2007-11-21 |
2007-11-20 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
3,700
+50.1%
9.12
US$33,744
|
3,700
+50.1%
|
9.12
|
US$33,744
|
|
|
2007-11-21 |
2007-11-20 |
B
Purchase
|
DOTZLER FREDERICK J
Non-Executive Director
|
100
+1.4%
9.04
US$904
|
100
+1.4%
|
9.04
|
US$904
|
|