|
2016-09-01 |
2016-04-21 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
91,653
-15.8%
193.24
US$2,589,565
|
91,653
-15.8%
|
193.24
|
US$2,589,565
|
|
|
2016-09-01 |
2016-04-21 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
39,257
-39.6%
259.38
US$2,406,336
|
39,257
-39.6%
|
259.38
|
US$2,406,336
|
|
|
2016-04-25 |
2016-04-21 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
97,685
+14.7%
125.80
US$2,844,679
|
97,685
+14.7%
|
125.80
|
US$2,844,679
|
|
|
2016-04-25 |
2016-04-21 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
17
-0.1%
13.55
US$230
|
17
-0.1%
|
13.55
|
US$230
|
|
|
2016-04-25 |
2016-04-21 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
1,982
-0.1%
13.55
US$26,856
|
1,982
-0.1%
|
13.55
|
US$26,856
|
|
|
2016-04-25 |
2016-04-21 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
2,299
-0.1%
13.55
US$31,151
|
2,299
-0.1%
|
13.55
|
US$31,151
|
|
|
2015-11-04 |
2015-11-04 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
3,898
-13.3%
15.45
US$60,224
|
3,898
-13.3%
|
15.45
|
US$60,224
|
|
|
2015-11-04 |
2015-11-04 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
532,119
-13.3%
15.45
US$8,221,239
|
532,119
-13.3%
|
15.45
|
US$8,221,239
|
|
|
2015-11-04 |
2015-11-04 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
5,382
-13.3%
15.45
US$83,152
|
5,382
-13.3%
|
15.45
|
US$83,152
|
|
|
2015-11-04 |
2015-11-04 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
458,601
-13.3%
15.45
US$7,085,385
|
458,601
-13.3%
|
15.45
|
US$7,085,385
|
|
|
2015-11-04 |
2015-11-03 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
490
-1.6%
16.32
US$7,997
|
490
-1.6%
|
16.32
|
US$7,997
|
|
|
2015-11-04 |
2015-11-03 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
66,793
-1.6%
16.32
US$1,090,062
|
66,793
-1.6%
|
16.32
|
US$1,090,062
|
|
|
2015-11-04 |
2015-11-03 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
675
-1.6%
16.32
US$11,016
|
675
-1.6%
|
16.32
|
US$11,016
|
|
|
2015-11-04 |
2015-11-03 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
57,565
-1.6%
16.32
US$939,461
|
57,565
-1.6%
|
16.32
|
US$939,461
|
|
|
2015-11-04 |
2015-11-02 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
680
-2.2%
16.87
US$11,471
|
680
-2.2%
|
16.87
|
US$11,471
|
|
|
2015-11-04 |
2015-11-02 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
939
-2.2%
16.87
US$15,840
|
939
-2.2%
|
16.87
|
US$15,840
|
|
|
2015-11-04 |
2015-11-02 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
92,843
-2.2%
16.87
US$1,566,215
|
92,843
-2.2%
|
16.87
|
US$1,566,215
|
|
|
2015-11-04 |
2015-11-02 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
80,015
-2.2%
16.87
US$1,349,813
|
80,015
-2.2%
|
16.87
|
US$1,349,813
|
|
|
2015-01-28 |
2015-01-27 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
50,000
-1.6%
26.19
US$1,309,475
|
50,000
-1.6%
|
26.19
|
US$1,309,475
|
|
|
2015-01-28 |
2015-01-26 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
28,041
-0.9%
26.12
US$732,313
|
28,041
-0.9%
|
26.12
|
US$732,313
|
|
|
2015-01-26 |
2015-01-23 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
61,883
-1.9%
25.90
US$1,602,912
|
61,883
-1.9%
|
25.90
|
US$1,602,912
|
|
|
2015-01-26 |
2015-01-22 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
150,000
-4.4%
25.49
US$3,823,140
|
150,000
-4.4%
|
25.49
|
US$3,823,140
|
|
|
2015-01-22 |
2015-01-21 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
44,316
-1.3%
25.22
US$1,117,645
|
44,316
-1.3%
|
25.22
|
US$1,117,645
|
|
|
2015-01-22 |
2015-01-20 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
25,000
-0.7%
25.24
US$630,932
|
25,000
-0.7%
|
25.24
|
US$630,932
|
|
|
2015-01-20 |
2015-01-16 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
50,000
-1.4%
25.26
US$1,262,900
|
50,000
-1.4%
|
25.26
|
US$1,262,900
|
|
|
2015-01-20 |
2015-01-15 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
75,000
-2.1%
25.10
US$1,882,500
|
75,000
-2.1%
|
25.10
|
US$1,882,500
|
|
|
2015-01-15 |
2015-01-14 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
50,000
-1.4%
25.53
US$1,276,695
|
50,000
-1.4%
|
25.53
|
US$1,276,695
|
|
|
2015-01-15 |
2015-01-13 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
50,000
-1.3%
25.49
US$1,274,635
|
50,000
-1.3%
|
25.49
|
US$1,274,635
|
|
|
2014-10-08 |
2014-10-08 |
PlS
Planned sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.8%
31.96
US$255,680
|
8,000
-1.8%
|
31.96
|
US$255,680
|
|
|
2014-09-25 |
2014-09-25 |
PlS
Planned sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.7%
29.72
US$237,760
|
8,000
-1.7%
|
29.72
|
US$237,760
|
|
|
2014-09-12 |
2014-09-12 |
PlS
Planned sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.7%
28.25
US$226,000
|
8,000
-1.7%
|
28.25
|
US$226,000
|
|
|
2014-08-29 |
2014-08-28 |
PlS
Planned sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.6%
27.07
US$216,560
|
8,000
-1.6%
|
27.07
|
US$216,560
|
|
|
2014-08-13 |
2014-08-12 |
PlS
Planned sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.6%
24.39
US$195,120
|
8,000
-1.6%
|
24.39
|
US$195,120
|
|
|
2014-07-31 |
2014-07-31 |
PlS
Planned sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.5%
25.20
US$201,600
|
8,000
-1.5%
|
25.20
|
US$201,600
|
|
|
2014-07-21 |
2014-07-18 |
S
Sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.5%
26.11
US$208,880
|
8,000
-1.5%
|
26.11
|
US$208,880
|
|
|
2014-07-21 |
2014-07-17 |
S
Sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.4%
26.25
US$210,000
|
8,000
-1.4%
|
26.25
|
US$210,000
|
|
|
2014-07-02 |
2014-07-02 |
S
Sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.4%
26.70
US$213,600
|
8,000
-1.4%
|
26.70
|
US$213,600
|
|
|
2014-07-02 |
2014-07-01 |
S
Sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.4%
26.31
US$210,480
|
8,000
-1.4%
|
26.31
|
US$210,480
|
|
|
2014-06-18 |
2014-06-18 |
S
Sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.4%
23.26
US$186,080
|
8,000
-1.4%
|
23.26
|
US$186,080
|
|
|
2014-06-18 |
2014-06-17 |
S
Sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.4%
23.47
US$187,760
|
8,000
-1.4%
|
23.47
|
US$187,760
|
|
|
2014-06-04 |
2014-06-04 |
S
Sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.3%
22.29
US$178,320
|
8,000
-1.3%
|
22.29
|
US$178,320
|
|
|
2014-06-04 |
2014-06-03 |
S
Sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.3%
22.05
US$176,400
|
8,000
-1.3%
|
22.05
|
US$176,400
|
|
|
2014-05-23 |
2014-05-22 |
S
Sale
|
FLANAGAN ROBERT J
Non-Executive Director
|
8,000
-1.3%
22.02
US$176,160
|
8,000
-1.3%
|
22.02
|
US$176,160
|
|
|
2014-02-28 |
2014-02-27 |
S
Sale
|
Logerfo Michael
Chief Legal Officer
Officer
|
2,021
-5.8%
21.43
US$43,310
|
2,021
-5.8%
|
21.43
|
US$43,310
|
|
|
2014-02-24 |
2014-02-20 |
S
Sale
|
Logerfo Michael
Chief Legal Officer
Officer
|
3,894
-9.7%
21.78
US$84,811
|
3,894
-9.7%
|
21.78
|
US$84,811
|
|
|
2014-02-24 |
2014-02-20 |
S
Sale
|
Logerfo Michael
Chief Legal Officer
Officer
|
4,638
-18.9%
22.05
US$102,268
|
4,638
-18.9%
|
22.05
|
US$102,268
|
|
|
2013-10-07 |
2013-10-03 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
47,826
-1.3%
20.27
US$969,275
|
47,826
-1.3%
|
20.27
|
US$969,275
|
|
|
2013-10-03 |
2013-10-01 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
50,000
-1.3%
20.70
US$1,035,030
|
50,000
-1.3%
|
20.70
|
US$1,035,030
|
|
|
2013-10-01 |
2013-09-30 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
25,000
-0.6%
20.38
US$509,615
|
25,000
-0.6%
|
20.38
|
US$509,615
|
|
|
2013-10-01 |
2013-09-30 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
28,872
-0.7%
20.46
US$590,828
|
28,872
-0.7%
|
20.46
|
US$590,828
|
|
|
2013-10-01 |
2013-09-27 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
10,000
-0.3%
20.60
US$206,000
|
10,000
-0.3%
|
20.60
|
US$206,000
|
|
|
2013-10-01 |
2013-09-27 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
31,300
-0.8%
20.52
US$642,188
|
31,300
-0.8%
|
20.52
|
US$642,188
|
|
|
2013-09-27 |
2013-09-26 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
67,965
-1.7%
20.37
US$1,384,304
|
67,965
-1.7%
|
20.37
|
US$1,384,304
|
|
|
2013-09-26 |
2013-09-25 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
33,431
-0.8%
21.22
US$709,352
|
33,431
-0.8%
|
21.22
|
US$709,352
|
|
|
2013-09-26 |
2013-09-24 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
14,693
-0.4%
21.50
US$315,839
|
14,693
-0.4%
|
21.50
|
US$315,839
|
|
|
2013-09-24 |
2013-09-23 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
27,843
-0.7%
21.42
US$596,358
|
27,843
-0.7%
|
21.42
|
US$596,358
|
|
|
2013-09-24 |
2013-09-20 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
91,714
-2.2%
21.96
US$2,013,819
|
91,714
-2.2%
|
21.96
|
US$2,013,819
|
|
|
2013-09-20 |
2013-09-19 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
39,842
-0.9%
22.15
US$882,421
|
39,842
-0.9%
|
22.15
|
US$882,421
|
|
|
2013-09-20 |
2013-09-18 |
S
Sale
|
MORGAN STANLEY INVESTMENT MANAGEMENT INC
Large shareholder
|
49,043
-1.1%
22.84
US$1,119,975
|
49,043
-1.1%
|
22.84
|
US$1,119,975
|
|
|
2013-09-18 |
2013-09-16 |
S
Sale
|
FLANAGAN ROBERT J
|
500,000
-45.1%
20.03
US$10,014,100
|
500,000
-45.1%
|
20.03
|
US$10,014,100
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
KUNG FRANK
Non-Executive Director
|
622,700
-13.0%
21.25
US$13,232,375
|
622,700
-13.0%
|
21.25
|
US$13,232,375
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
6,252
-13.0%
21.25
US$132,855
|
6,252
-13.0%
|
21.25
|
US$132,855
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
4,529
-13.0%
21.25
US$96,241
|
4,529
-13.0%
|
21.25
|
US$96,241
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
KUNG FRANK
|
539,017
-13.0%
21.25
US$11,454,111
|
539,017
-13.0%
|
21.25
|
US$11,454,111
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
Vivo Ventures V, LLC
Large shareholder
|
532,765
-13.0%
21.25
US$11,321,256
|
532,765
-13.0%
|
21.25
|
US$11,321,256
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
Vivo Ventures VI, LLC
Large shareholder
|
618,171
-13.0%
21.25
US$13,136,134
|
618,171
-13.0%
|
21.25
|
US$13,136,134
|
|
|
2013-09-17 |
2013-09-16 |
S
Sale
|
YORDON JEFFREY
Chief Executive Officer
|
85,813
-11.4%
20.03
US$1,718,680
|
85,813
-11.4%
|
20.03
|
US$1,718,680
|
|
|
2013-08-13 |
2013-08-12 |
S
Sale
|
Drake Lorin
Corporate VP, Sales
Officer
|
1,000
-4.4%
23.69
US$23,690
|
1,000
-4.4%
|
23.69
|
US$23,690
|
|
|
2012-11-20 |
2012-11-19 |
S
Sale
|
Logerfo Michael
Chief Legal Officer
Officer
|
6,867
-33.5%
14.64
US$100,533
|
6,867
-33.5%
|
14.64
|
US$100,533
|
|
|
2012-11-20 |
2012-11-16 |
S
Sale
|
Logerfo Michael
Chief Legal Officer
Officer
|
2,271
-10.0%
14.68
US$33,338
|
2,271
-10.0%
|
14.68
|
US$33,338
|
|
|
2012-11-16 |
2012-11-15 |
S
Sale
|
Logerfo Michael
Chief Legal Officer
Officer
|
9,000
-28.3%
14.38
US$129,420
|
9,000
-28.3%
|
14.38
|
US$129,420
|
|
|
2012-11-16 |
2012-11-14 |
S
Sale
|
Logerfo Michael
Chief Legal Officer
Officer
|
1,000
-6.5%
14.56
US$14,560
|
1,000
-6.5%
|
14.56
|
US$14,560
|
|
|
2012-05-29 |
2012-05-25 |
S
Sale
|
Logerfo Michael
Chief Legal Officer
Officer
|
7,000
-34.0%
15.86
US$111,020
|
7,000
-34.0%
|
15.86
|
US$111,020
|
|
|
2012-05-18 |
2012-05-17 |
B
Purchase
|
Logerfo Michael
Chief Legal Officer
Officer
|
2,000
+10.7%
15.69
US$31,380
|
2,000
+10.7%
|
15.69
|
US$31,380
|
|
|
2012-02-17 |
2012-02-17 |
S
Sale
|
China Renaissance Capital Investment II GP
Large shareholder
|
76,700
-2.7%
22.07
US$1,692,769
|
76,700
-2.7%
|
22.07
|
US$1,692,769
|
|