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United States Biotechnology & Medical Research

Protagonist Therapeutics Inc (PTGX)

Track

Over the last 90 days, Protagonist Therapeutics Inc. has seen significant insider selling, with a net value of over $24 million. Executives contributed over $11 million to this net selling. Notable transactions include large sales by CEO Dinesh Patel and Director William Waddill, occurring around the time of the last earnings report which significantly beat expectations.
Stock chart
Ticker: PTGX Exchange: NMS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
WILLIAM WADDILL
Director
1 sale — total 100,000 USD
Proposed sale 23 Jun 2026
Value US$4,402,703.21 | Price 484.51 | Shares 74,803
Sale 10 Jun 2026
Value US$4,794,652.15 | Price 333.16 | Shares 58,329
Sale 10 Jun 2026
Value US$1,692,229.04 | Price 436.73 | Shares 52,600
Sale 10 Jun 2026
Value US$100,000.00 | Price 107.68 | Shares 1,000
Proposed sale 10 Jun 2026
Value US$100,000.00 | Price 105.87 | Shares 1,000
Sale 29 May 2026
Value US$896,760.00 | Price 99.64 | Shares 9,000
Proposed sale 29 May 2026
Value US$903,690.00 | Price 100.41 | Shares 9,000
Sale 12 May 2026
Value US$7,509,000.00 | Price 100.12 | Shares 75,000
Proposed sale 12 May 2026
Value US$7,762,500.00 | Price 103.50 | Shares 75,000
Sale 8 May 2026
Value US$513,000.00 | Price 100.00 | Shares 5,130
Sale 8 May 2026
Value US$600,000.00 | Price 100.00 | Shares 6,000
Proposed sale 8 May 2026
Value US$1,113,000.00 | Price 100.00 | Shares 11,130
Sale 7 May 2026
Value US$1,200,840.00 | Price 100.07 | Shares 12,000
Sale 7 May 2026
Value US$3,605,040.00 | Price 100.14 | Shares 36,000
Proposed sale 7 May 2026
Value US$3,604,968.00 | Price 100.14 | Shares 36,000
Proposed sale 7 May 2026
Value US$1,200,873.60 | Price 100.07 | Shares 12,000
Sale 20 Apr 2026
Value US$184,572.50 | Price 105.47 | Shares 1,750
Proposed sale 20 Apr 2026
Value US$184,572.50 | Price 105.47 | Shares 1,750
Sale 26 Mar 2026
Value US$2,581,503.60 | Price 104.24 | Shares 24,765
Sale 26 Mar 2026
Value US$1,571,850.00 | Price 104.79 | Shares 15,000
Sale 26 Mar 2026
Value US$2,520,000.00 | Price 105.00 | Shares 24,000
Proposed sale 26 Mar 2026
Value US$1,571,919.00 | Price 104.79 | Shares 15,000
Proposed sale 26 Mar 2026
Value US$2,581,545.70 | Price 104.24 | Shares 24,765
Proposed sale 26 Mar 2026
Value US$2,520,000.00 | Price 105.00 | Shares 24,000
Sale 25 Mar 2026
Value US$5,518,741.00 | Price 101.00 | Shares 54,641
Sale 24 Mar 2026
Value US$5,959.00 | Price 101.00 | Shares 59
Proposed sale 24 Mar 2026
Value US$5,390,138.00 | Price 98.54 | Shares 54,700
Sale 17 Feb 2026
Value US$1,483,560.00 | Price 82.42 | Shares 18,000
Proposed sale 17 Feb 2026
Value US$1,483,495.20 | Price 82.42 | Shares 18,000
Sale 6 Feb 2026
Value US$1,673,600.00 | Price 83.68 | Shares 20,000
Proposed sale 6 Feb 2026
Value US$1,673,672.00 | Price 83.68 | Shares 20,000
Proposed sale 27 Jan 2026
Value US$3,841,128.28 | Price 83.14 | Shares 46,203
Proposed sale 27 Jan 2026
Value US$410,000.00 | Price 82.00 | Shares 5,000
Sale 27 Jan 2026
Value US$338,416.92 | Price 83.19 | Shares 4,068
Sale 27 Jan 2026
Value US$410,000.00 | Price 82.00 | Shares 5,000
Sale 27 Jan 2026
Value US$1,513,397.42 | Price 83.14 | Shares 18,203
Sale 27 Jan 2026
Value US$2,327,640.00 | Price 83.13 | Shares 28,000
Sale 26 Jan 2026
Value US$1,193,930.25 | Price 84.05 | Shares 14,205
Sale 26 Jan 2026
Value US$897,540.00 | Price 84.00 | Shares 10,685
Sale 26 Jan 2026
Value US$411,400.00 | Price 82.28 | Shares 5,000
Proposed sale 26 Jan 2026
Value US$411,396.00 | Price 82.28 | Shares 5,000
Sale 23 Jan 2026
Value US$1,633,855.85 | Price 84.59 | Shares 19,315
Sale 23 Jan 2026
Value US$1,083,905.42 | Price 82.42 | Shares 13,151
Proposed sale 23 Jan 2026
Value US$9,162,061.00 | Price 84.62 | Shares 108,273
Proposed sale 23 Jan 2026
Value US$1,097,115.60 | Price 83.42 | Shares 13,151
Proposed sale 20 Jan 2026
Value US$784,714.72 | Price 82.48 | Shares 9,514
Proposed sale 20 Jan 2026
Value US$2,840,446.24 | Price 82.48 | Shares 34,438
Proposed sale 20 Jan 2026
Value US$708,338.24 | Price 82.48 | Shares 8,588
Sale 20 Jan 2026
Value US$784,714.72 | Price 82.48 | Shares 9,514
Sale 20 Jan 2026
Value US$2,840,446.24 | Price 82.48 | Shares 34,438
Sale 20 Jan 2026
Value US$708,338.24 | Price 82.48 | Shares 8,588
Sale 17 Nov 2025
Value US$229,896.24 | Price 84.77 | Shares 2,712
Planned sale 10 Oct 2025
Value US$702,480.00 | Price 87.81 | Shares 8,000
Planned sale 10 Oct 2025
Value US$277,000.00 | Price 69.25 | Shares 4,000
Proposed sale 10 Oct 2025
Value US$804,480.00 | Price 67.04 | Shares 12,000
Planned sale 22 Sep 2025
Value US$257,000.00 | Price 64.25 | Shares 4,000
Proposed sale 22 Sep 2025
Value US$248,800.00 | Price 62.20 | Shares 4,000
Planned sale 27 Aug 2025
Value US$237,000.00 | Price 59.25 | Shares 4,000
Proposed sale 27 Aug 2025
Value US$227,960.00 | Price 56.99 | Shares 4,000
Sale 25 Jul 2025
Value US$570,533.70 | Price 54.78 | Shares 10,415
Sale 23 Jul 2025
Value US$959,920.80 | Price 54.79 | Shares 17,520
Sale 22 Jul 2025
Value US$1,214,678.25 | Price 55.05 | Shares 22,065
Proposed sale 22 Jul 2025
Value US$2,761,000.00 | Price 55.22 | Shares 50,000
Sale 21 Jul 2025
Value US$705,444.74 | Price 54.86 | Shares 12,859
Sale 10 Jun 2025
Value US$570,300.00 | Price 57.03 | Shares 10,000
Proposed sale 10 Jun 2025
Value US$570,269.00 | Price 57.03 | Shares 10,000
Sale 9 Jun 2025
Value US$555,100.00 | Price 55.51 | Shares 10,000
Proposed sale 9 Jun 2025
Value US$555,077.00 | Price 55.51 | Shares 10,000
Sale 22 Apr 2025
Value US$80,776.00 | Price 46.00 | Shares 1,756
Planned sale 17 Mar 2025
Value US$217,000.00 | Price 54.25 | Shares 4,000
Proposed sale 17 Mar 2025
Value US$219,120.00 | Price 54.78 | Shares 4,000
Sale 13 Mar 2025
Value US$1,700,850.36 | Price 55.74 | Shares 30,514
Proposed sale 13 Mar 2025
Value US$1,678,270.00 | Price 55.00 | Shares 30,514
Sale 12 Mar 2025
Value US$1,462,553.19 | Price 58.73 | Shares 24,903
Proposed sale 12 Mar 2025
Value US$1,462,587.48 | Price 58.73 | Shares 24,903
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-06-23 2026-06-23 PrS Proposed sale
2.3
WILLIAM WADDILL

Director

Non-Executive Director
74,803
484.51
US$4,402,703 		74,803 484.51 US$4,402,703
2026-06-11 2026-06-10 S Sale
2.3
Waddill William D.
Non-Executive Director
58,329 -1.7%
333.16
US$4,794,652 		58,329 -1.7% 333.16 US$4,794,652
2026-06-11 2026-06-10 S Sale
2.3
Waddill William D.
Non-Executive Director
52,600 +49.5%
436.73
US$1,692,229 		52,600 +49.5% 436.73 US$1,692,229
2026-06-11 2026-06-10 S Sale
2.3
Waddill William D.
Non-Executive Director
1,000 -53.5%
107.68
US$100,000 		1,000 -53.5% 107.68 US$100,000
2026-06-10 2026-06-10 PrS Proposed sale
2.3
WILLIAM WADDILL

Director

Non-Executive Director
1,000
105.87
US$100,000 		1,000 105.87 US$100,000
2026-06-01 2026-05-29 S Sale
2.3
Waddill William D.
Non-Executive Director
9,000 -53.5%
99.64
US$896,760 		9,000 -53.5% 99.64 US$896,760
2026-05-29 2026-05-29 PrS Proposed sale
2.3
WILLIAM WADDILL

Director

Non-Executive Director
9,000
100.41
US$903,690 		9,000 100.41 US$903,690
2026-05-12 2026-05-12 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
75,000 -12.5%
100.12
US$7,509,000 		75,000 -12.5% 100.12 US$7,509,000
2026-05-12 2026-05-12 PrS Proposed sale
2.2
Dinesh Patel

CEO
75,000
103.50
US$7,762,500 		75,000 103.50 US$7,762,500
2026-05-11 2026-05-08 S Sale
3.0
Giraudo Bryan
Non-Executive Director
5,130 -28.8%
100.00
US$513,000 		5,130 -28.8% 100.00 US$513,000
2026-05-11 2026-05-08 S Sale
3.0
Giraudo Bryan
Non-Executive Director
6,000 -100.0%
100.00
US$600,000 		6,000 -100.0% 100.00 US$600,000
2026-05-08 2026-05-08 PrS Proposed sale
3.0
BRYAN M & COURTNEY L GIRAUDO RT

Director

Non-Executive Director
11,130
100.00
US$1,113,000 		11,130 100.00 US$1,113,000
2026-05-11 2026-05-07 S Sale
3.0
Giraudo Bryan
Non-Executive Director
12,000 -66.7%
100.07
US$1,200,840 		12,000 -66.7% 100.07 US$1,200,840
2026-05-11 2026-05-07 S Sale
3.0
Giraudo Bryan
Non-Executive Director
36,000 -56.4%
100.14
US$3,605,040 		36,000 -56.4% 100.14 US$3,605,040
2026-05-07 2026-05-07 PrS Proposed sale
3.0
BRYAN GIRAUDO

Director

Non-Executive Director
36,000
100.14
US$3,604,968 		36,000 100.14 US$3,604,968
2026-05-07 2026-05-07 PrS Proposed sale
3.0
BRYAN M & COURTNEY L GIRAUDO RT

Director

Non-Executive Director
12,000
100.07
US$1,200,874 		12,000 100.07 US$1,200,874
2026-04-21 2026-04-20 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
1,750 -2.9%
105.47
US$184,572 		1,750 -2.9% 105.47 US$184,572
2026-04-21 2026-04-20 PrS Proposed sale
2.7
Asif Ali

Officer

Officer
1,750
105.47
US$184,572 		1,750 105.47 US$184,572
2026-03-27 2026-03-26 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
24,765 -29.0%
104.24
US$2,581,504 		24,765 -29.0% 104.24 US$2,581,504
2026-03-27 2026-03-26 S Sale
3.0
MOLINA ARTURO MD

Chief Medical Officer

Officer
15,000 -15.1%
104.79
US$1,571,850 		15,000 -15.1% 104.79 US$1,571,850
2026-03-27 2026-03-26 S Sale
3.4
SELICK HAROLD E
Non-Executive Director
24,000 -28.3%
105.00
US$2,520,000 		24,000 -28.3% 105.00 US$2,520,000
2026-03-26 2026-03-26 PrS Proposed sale
3.0
ARTURO MOLINA

Officer

Officer
15,000
104.79
US$1,571,919 		15,000 104.79 US$1,571,919
2026-03-26 2026-03-26 PrS Proposed sale
2.7
ASIF ALI

Officer

Officer
24,765
104.24
US$2,581,546 		24,765 104.24 US$2,581,546
2026-03-26 2026-03-26 PrS Proposed sale
3.4
HAROLD SELICK

Director

Non-Executive Director
24,000
105.00
US$2,520,000 		24,000 105.00 US$2,520,000
2026-03-25 2026-03-25 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
54,641 -9.4%
101.00
US$5,518,741 		54,641 -9.4% 101.00 US$5,518,741
2026-03-25 2026-03-24 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
59 -0.0%
101.00
US$5,959 		59 -0.0% 101.00 US$5,959
2026-03-24 2026-03-24 PrS Proposed sale
2.2
Dinesh Patel

CEO
54,700
98.54
US$5,390,138 		54,700 98.54 US$5,390,138
2026-02-18 2026-02-17 S Sale
Williams Lewis T
Non-Executive Director
18,000 -69.7%
82.42
US$1,483,560 		18,000 -69.7% 82.42 US$1,483,560
2026-02-17 2026-02-17 PrS Proposed sale
LEWIS T WILLIAMS

Director

Non-Executive Director
18,000
82.42
US$1,483,495 		18,000 82.42 US$1,483,495
2026-02-06 2026-02-06 S Sale
2.3
Waddill William D.
Non-Executive Director
20,000 -71.9%
83.68
US$1,673,600 		20,000 -71.9% 83.68 US$1,673,600
2026-02-06 2026-02-06 PrS Proposed sale
2.3
WILLIAM D WADDILL

Director

Non-Executive Director
20,000
83.68
US$1,673,672 		20,000 83.68 US$1,673,672
2026-01-27 2026-01-27 PrS Proposed sale
2.7
ASIF ALI

Officer

Officer
46,203
83.14
US$3,841,128 		46,203 83.14 US$3,841,128
2026-01-27 2026-01-27 PrS Proposed sale
3.0
ARTURO MOLINA

Officer

Officer
5,000
82.00
US$410,000 		5,000 82.00 US$410,000
2026-01-27 2026-01-27 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
4,068 -0.7%
83.19
US$338,417 		4,068 -0.7% 83.19 US$338,417
2026-01-27 2026-01-27 S Sale
3.0
MOLINA ARTURO MD

Chief Medical Officer

Officer
5,000 -5.6%
82.00
US$410,000 		5,000 -5.6% 82.00 US$410,000
2026-01-27 2026-01-27 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
18,203 -23.2%
83.14
US$1,513,397 		18,203 -23.2% 83.14 US$1,513,397
2026-01-27 2026-01-27 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
28,000 -26.3%
83.13
US$2,327,640 		28,000 -26.3% 83.13 US$2,327,640
2026-01-27 2026-01-26 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
14,205 -2.4%
84.05
US$1,193,930 		14,205 -2.4% 84.05 US$1,193,930
2026-01-27 2026-01-26 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
10,685 -1.8%
84.00
US$897,540 		10,685 -1.8% 84.00 US$897,540
2026-01-27 2026-01-26 S Sale
3.0
MOLINA ARTURO MD

Chief Medical Officer

Officer
5,000 -5.6%
82.28
US$411,400 		5,000 -5.6% 82.28 US$411,400
2026-01-26 2026-01-26 PrS Proposed sale
3.0
ARTURO MOLINA

Officer

Officer
5,000
82.28
US$411,396 		5,000 82.28 US$411,396
2026-01-27 2026-01-23 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
19,315 -3.3%
84.59
US$1,633,856 		19,315 -3.3% 84.59 US$1,633,856
2026-01-27 2026-01-23 S Sale
3.0
MOLINA ARTURO MD

Chief Medical Officer

Officer
13,151 -13.5%
82.42
US$1,083,905 		13,151 -13.5% 82.42 US$1,083,905
2026-01-23 2026-01-23 PrS Proposed sale
2.2
Dinesh Patel

CEO
108,273
84.62
US$9,162,061 		108,273 84.62 US$9,162,061
2026-01-23 2026-01-23 PrS Proposed sale
3.0
ARTURO MOLINA

Officer

Officer
13,151
83.42
US$1,097,116 		13,151 83.42 US$1,097,116
2026-01-21 2026-01-20 PrS Proposed sale
3.0
ARTURO MOLINA MD

Officer

Officer
9,514
82.48
US$784,715 		9,514 82.48 US$784,715
2026-01-21 2026-01-20 PrS Proposed sale
2.2
DINESH V PATEL PH D

Officer, Director

Executive Director
34,438
82.48
US$2,840,446 		34,438 82.48 US$2,840,446
2026-01-21 2026-01-20 PrS Proposed sale
2.7
Asif Ali

Officer

Officer
8,588
82.48
US$708,338 		8,588 82.48 US$708,338
2026-01-21 2026-01-20 S Sale
3.0
MOLINA ARTURO MD

Chief Medical Officer

Officer
9,514 -8.9%
82.48
US$784,715 		9,514 -8.9% 82.48 US$784,715
2026-01-21 2026-01-20 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
34,438 -5.6%
82.48
US$2,840,446 		34,438 -5.6% 82.48 US$2,840,446
2026-01-21 2026-01-20 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
8,588 -9.9%
82.48
US$708,338 		8,588 -9.9% 82.48 US$708,338
2025-11-19 2025-11-17 S Sale
3.0
MOLINA ARTURO MD

Chief Medical Officer

Officer
2,712 -3.2%
84.77
US$229,896 		2,712 -3.2% 84.77 US$229,896
2025-10-14 2025-10-10 PlS Planned sale
2.3
Waddill William D.
Non-Executive Director
8,000 -60.9%
87.81
US$702,480 		8,000 -60.9% 87.81 US$702,480
2025-10-14 2025-10-10 PlS Planned sale
2.3
Waddill William D.
Non-Executive Director
4,000 -23.4%
69.25
US$277,000 		4,000 -23.4% 69.25 US$277,000
2025-10-10 2025-10-10 PrS Proposed sale
2.3
WILLIAM WADDILL

Director

Non-Executive Director
12,000
67.04
US$804,480 		12,000 67.04 US$804,480
2025-09-24 2025-09-22 PlS Planned sale
2.3
Waddill William D.
Non-Executive Director
4,000 -43.8%
64.25
US$257,000 		4,000 -43.8% 64.25 US$257,000
2025-09-22 2025-09-22 PrS Proposed sale
2.3
WILLIAM WADDILL

Director

Non-Executive Director
4,000
62.20
US$248,800 		4,000 62.20 US$248,800
2025-08-29 2025-08-27 PlS Planned sale
2.3
Waddill William D.
Non-Executive Director
4,000 -30.5%
59.25
US$237,000 		4,000 -30.5% 59.25 US$237,000
2025-08-27 2025-08-27 PrS Proposed sale
2.3
WILLIAM WADDILL

Director

Non-Executive Director
4,000
56.99
US$227,960 		4,000 56.99 US$227,960
2025-07-28 2025-07-25 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
10,415 -2.0%
54.78
US$570,534 		10,415 -2.0% 54.78 US$570,534
2025-07-23 2025-07-23 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
17,520 -3.2%
54.79
US$959,921 		17,520 -3.2% 54.79 US$959,921
2025-07-23 2025-07-22 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
22,065 -3.9%
55.05
US$1,214,678 		22,065 -3.9% 55.05 US$1,214,678
2025-07-22 2025-07-22 PrS Proposed sale
2.2
Dinesh Patel

CEO
50,000
55.22
US$2,761,000 		50,000 55.22 US$2,761,000
2025-07-23 2025-07-21 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
12,859 -2.2%
54.86
US$705,445 		12,859 -2.2% 54.86 US$705,445
2025-06-11 2025-06-10 S Sale
3.0
MOLINA ARTURO MD

Chief Medical Officer

Officer
10,000 -10.7%
57.03
US$570,300 		10,000 -10.7% 57.03 US$570,300
2025-06-10 2025-06-10 PrS Proposed sale
3.0
ARTURO MOLINA

Officer

Officer
10,000
57.03
US$570,269 		10,000 57.03 US$570,269
2025-06-11 2025-06-09 S Sale
3.0
MOLINA ARTURO MD

Chief Medical Officer

Officer
10,000 -10.7%
55.51
US$555,100 		10,000 -10.7% 55.51 US$555,100
2025-06-09 2025-06-09 PrS Proposed sale
3.0
ARTURO MOLINA

Officer

Officer
10,000
55.51
US$555,077 		10,000 55.51 US$555,077
2025-04-23 2025-04-22 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
1,756 -2.8%
46.00
US$80,776 		1,756 -2.8% 46.00 US$80,776
2025-03-19 2025-03-17 PlS Planned sale
2.3
Waddill William D.
Non-Executive Director
4,000 -23.4%
54.25
US$217,000 		4,000 -23.4% 54.25 US$217,000
2025-03-17 2025-03-17 PrS Proposed sale
2.3
WILLIAM D WADDILL

Director

Non-Executive Director
4,000
54.78
US$219,120 		4,000 54.78 US$219,120
2025-03-14 2025-03-13 S Sale
3.0
MOLINA ARTURO MD

Chief Medical Officer

Officer
30,514 -26.7%
55.74
US$1,700,850 		30,514 -26.7% 55.74 US$1,700,850
2025-03-13 2025-03-13 PrS Proposed sale
3.0
MOLINA ARTURO MD

Officer

Officer
30,514
55.00
US$1,678,270 		30,514 55.00 US$1,678,270
2025-03-14 2025-03-12 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
24,903 -28.4%
58.73
US$1,462,553 		24,903 -28.4% 58.73 US$1,462,553
2025-03-12 2025-03-12 PrS Proposed sale
2.7
Ali Asif

Officer

Officer
24,903
58.73
US$1,462,587 		24,903 58.73 US$1,462,587
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