United States Biotechnology & Medical Research

Protagonist Therapeutics Inc (PTGX)

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Protagonist Therapeutics experienced significant insider trading activity recently, totaling nine transactions. Executives and directors offloaded shares valued at approximately 41.3 million dollars. These divestments followed positive results financiers, occurring while the stock price traded near its fifty-two-week peak after a 44.4 percent quarterly gain.
Ticker: PTGX Exchange: NMS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Proposed sale 10 Aug 2026
Value US$2,720,096.18 | Price 242.58 | Shares 86,307
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-08-10 2026-08-10 PrS Proposed sale
2.2
Dinesh Patel

CEO
86,307
242.58
US$2,720,096 		86,307 242.58 US$2,720,096
2026-06-25 2026-06-23 S Sale
2.2
Waddill William D.
Non-Executive Director
36,935 +36.6%
82.21
US$2,653,459 		36,935 +36.6% 82.21 US$2,653,459
2026-06-23 2026-06-23 PrS Proposed sale
2.2
WILLIAM WADDILL

Director

Non-Executive Director
74,803
484.51
US$4,402,703 		74,803 484.51 US$4,402,703
2026-06-11 2026-06-10 S Sale
2.2
Waddill William D.
Non-Executive Director
9,000 -53.5%
107.68
US$969,120 		9,000 -53.5% 107.68 US$969,120
2026-06-11 2026-06-10 S Sale
2.2
Waddill William D.
Non-Executive Director
9,000 -53.5%
107.68
US$969,120 		9,000 -53.5% 107.68 US$969,120
2026-06-11 2026-06-10 S Sale
2.2
Waddill William D.
Non-Executive Director
9,000 -53.5%
107.68
US$969,120 		9,000 -53.5% 107.68 US$969,120
2026-06-10 2026-06-10 PrS Proposed sale
2.2
WILLIAM WADDILL

Director

Non-Executive Director
9,000
105.87
US$952,830 		9,000 105.87 US$952,830
2026-06-01 2026-05-29 S Sale
2.2
Waddill William D.
Non-Executive Director
9,000 -53.5%
99.64
US$896,760 		9,000 -53.5% 99.64 US$896,760
2026-05-29 2026-05-29 PrS Proposed sale
2.2
WILLIAM WADDILL

Director

Non-Executive Director
9,000
100.41
US$903,690 		9,000 100.41 US$903,690
2026-05-12 2026-05-12 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
75,000 -12.5%
100.12
US$7,509,000 		75,000 -12.5% 100.12 US$7,509,000
2026-05-12 2026-05-12 PrS Proposed sale
2.2
Dinesh Patel

CEO
75,000
103.50
US$7,762,500 		75,000 103.50 US$7,762,500
2026-05-11 2026-05-08 S Sale
2.6
Giraudo Bryan
Non-Executive Director
5,130 -28.8%
100.00
US$513,000 		5,130 -28.8% 100.00 US$513,000
2026-05-11 2026-05-08 S Sale
2.6
Giraudo Bryan
Non-Executive Director
6,000 -100.0%
100.00
US$600,000 		6,000 -100.0% 100.00 US$600,000
2026-05-08 2026-05-08 PrS Proposed sale
2.6
BRYAN M & COURTNEY L GIRAUDO RT

Director

Non-Executive Director
11,130
100.00
US$1,113,000 		11,130 100.00 US$1,113,000
2026-05-11 2026-05-07 S Sale
2.6
Giraudo Bryan
Non-Executive Director
12,000 -66.7%
100.07
US$1,200,840 		12,000 -66.7% 100.07 US$1,200,840
2026-05-11 2026-05-07 S Sale
2.6
Giraudo Bryan
Non-Executive Director
36,000 -56.4%
100.14
US$3,605,040 		36,000 -56.4% 100.14 US$3,605,040
2026-05-07 2026-05-07 PrS Proposed sale
2.6
BRYAN GIRAUDO

Director

Non-Executive Director
36,000
100.14
US$3,604,968 		36,000 100.14 US$3,604,968
2026-05-07 2026-05-07 PrS Proposed sale
2.6
BRYAN M & COURTNEY L GIRAUDO RT

Director

Non-Executive Director
12,000
100.07
US$1,200,874 		12,000 100.07 US$1,200,874
2026-04-21 2026-04-20 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
1,750 -2.9%
105.47
US$184,572 		1,750 -2.9% 105.47 US$184,572
2026-04-21 2026-04-20 PrS Proposed sale
2.7
Asif Ali

Officer

Officer
1,750
105.47
US$184,572 		1,750 105.47 US$184,572
2026-03-27 2026-03-26 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
24,765 -29.0%
104.24
US$2,581,504 		24,765 -29.0% 104.24 US$2,581,504
2026-03-27 2026-03-26 S Sale
2.9
MOLINA ARTURO MD

Chief Medical Officer

Officer
15,000 -15.1%
104.79
US$1,571,850 		15,000 -15.1% 104.79 US$1,571,850
2026-03-27 2026-03-26 S Sale
2.7
SELICK HAROLD E
Non-Executive Director
24,000 -28.3%
105.00
US$2,520,000 		24,000 -28.3% 105.00 US$2,520,000
2026-03-26 2026-03-26 PrS Proposed sale
2.9
ARTURO MOLINA

Officer

Officer
15,000
104.79
US$1,571,919 		15,000 104.79 US$1,571,919
2026-03-26 2026-03-26 PrS Proposed sale
2.7
ASIF ALI

Officer

Officer
24,765
104.24
US$2,581,546 		24,765 104.24 US$2,581,546
2026-03-26 2026-03-26 PrS Proposed sale
2.7
HAROLD SELICK

Director

Non-Executive Director
24,000
105.00
US$2,520,000 		24,000 105.00 US$2,520,000
2026-03-25 2026-03-25 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
54,641 -9.4%
101.00
US$5,518,741 		54,641 -9.4% 101.00 US$5,518,741
2026-03-25 2026-03-24 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
59 -0.0%
101.00
US$5,959 		59 -0.0% 101.00 US$5,959
2026-03-24 2026-03-24 PrS Proposed sale
2.2
Dinesh Patel

CEO
54,700
98.54
US$5,390,138 		54,700 98.54 US$5,390,138
2026-02-18 2026-02-17 S Sale
0.6
Williams Lewis T
Non-Executive Director
18,000 -69.7%
82.42
US$1,483,560 		18,000 -69.7% 82.42 US$1,483,560
2026-02-17 2026-02-17 PrS Proposed sale
0.6
LEWIS T WILLIAMS

Director

Non-Executive Director
18,000
82.42
US$1,483,495 		18,000 82.42 US$1,483,495
2026-02-06 2026-02-06 S Sale
2.2
Waddill William D.
Non-Executive Director
20,000 -71.9%
83.68
US$1,673,600 		20,000 -71.9% 83.68 US$1,673,600
2026-02-06 2026-02-06 PrS Proposed sale
2.2
WILLIAM D WADDILL

Director

Non-Executive Director
20,000
83.68
US$1,673,672 		20,000 83.68 US$1,673,672
2026-01-27 2026-01-27 PrS Proposed sale
2.7
ASIF ALI

Officer

Officer
46,203
83.14
US$3,841,128 		46,203 83.14 US$3,841,128
2026-01-27 2026-01-27 PrS Proposed sale
2.9
ARTURO MOLINA

Officer

Officer
5,000
82.00
US$410,000 		5,000 82.00 US$410,000
2026-01-27 2026-01-27 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
4,068 -0.7%
83.19
US$338,417 		4,068 -0.7% 83.19 US$338,417
2026-01-27 2026-01-27 S Sale
2.9
MOLINA ARTURO MD

Chief Medical Officer

Officer
5,000 -5.6%
82.00
US$410,000 		5,000 -5.6% 82.00 US$410,000
2026-01-27 2026-01-27 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
18,203 -23.2%
83.14
US$1,513,397 		18,203 -23.2% 83.14 US$1,513,397
2026-01-27 2026-01-27 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
28,000 -26.3%
83.13
US$2,327,640 		28,000 -26.3% 83.13 US$2,327,640
2026-01-27 2026-01-26 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
14,205 -2.4%
84.05
US$1,193,930 		14,205 -2.4% 84.05 US$1,193,930
2026-01-27 2026-01-26 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
10,685 -1.8%
84.00
US$897,540 		10,685 -1.8% 84.00 US$897,540
2026-01-27 2026-01-26 S Sale
2.9
MOLINA ARTURO MD

Chief Medical Officer

Officer
5,000 -5.6%
82.28
US$411,400 		5,000 -5.6% 82.28 US$411,400
2026-01-26 2026-01-26 PrS Proposed sale
2.9
ARTURO MOLINA

Officer

Officer
5,000
82.28
US$411,396 		5,000 82.28 US$411,396
2026-01-27 2026-01-23 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
19,315 -3.3%
84.59
US$1,633,856 		19,315 -3.3% 84.59 US$1,633,856
2026-01-27 2026-01-23 S Sale
2.9
MOLINA ARTURO MD

Chief Medical Officer

Officer
13,151 -13.5%
82.42
US$1,083,905 		13,151 -13.5% 82.42 US$1,083,905
2026-01-23 2026-01-23 PrS Proposed sale
2.2
Dinesh Patel

CEO
108,273
84.62
US$9,162,061 		108,273 84.62 US$9,162,061
2026-01-23 2026-01-23 PrS Proposed sale
2.9
ARTURO MOLINA

Officer

Officer
13,151
83.42
US$1,097,116 		13,151 83.42 US$1,097,116
2026-01-21 2026-01-20 PrS Proposed sale
2.9
ARTURO MOLINA MD

Officer

Officer
9,514
82.48
US$784,715 		9,514 82.48 US$784,715
2026-01-21 2026-01-20 PrS Proposed sale
2.2
DINESH V PATEL PH D

Officer, Director

Executive Director
34,438
82.48
US$2,840,446 		34,438 82.48 US$2,840,446
2026-01-21 2026-01-20 PrS Proposed sale
2.7
Asif Ali

Officer

Officer
8,588
82.48
US$708,338 		8,588 82.48 US$708,338
2026-01-21 2026-01-20 S Sale
2.9
MOLINA ARTURO MD

Chief Medical Officer

Officer
9,514 -8.9%
82.48
US$784,715 		9,514 -8.9% 82.48 US$784,715
2026-01-21 2026-01-20 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
34,438 -5.6%
82.48
US$2,840,446 		34,438 -5.6% 82.48 US$2,840,446
2026-01-21 2026-01-20 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
8,588 -9.9%
82.48
US$708,338 		8,588 -9.9% 82.48 US$708,338
2025-11-19 2025-11-17 S Sale
2.9
MOLINA ARTURO MD

Chief Medical Officer

Officer
2,712 -3.2%
84.77
US$229,896 		2,712 -3.2% 84.77 US$229,896
2025-10-14 2025-10-10 PlS Planned sale
2.2
Waddill William D.
Non-Executive Director
8,000 -60.9%
87.81
US$702,480 		8,000 -60.9% 87.81 US$702,480
2025-10-14 2025-10-10 PlS Planned sale
2.2
Waddill William D.
Non-Executive Director
4,000 -23.4%
69.25
US$277,000 		4,000 -23.4% 69.25 US$277,000
2025-10-10 2025-10-10 PrS Proposed sale
2.2
WILLIAM WADDILL

Director

Non-Executive Director
12,000
67.04
US$804,480 		12,000 67.04 US$804,480
2025-09-24 2025-09-22 PlS Planned sale
2.2
Waddill William D.
Non-Executive Director
4,000 -43.8%
64.25
US$257,000 		4,000 -43.8% 64.25 US$257,000
2025-09-22 2025-09-22 PrS Proposed sale
2.2
WILLIAM WADDILL

Director

Non-Executive Director
4,000
62.20
US$248,800 		4,000 62.20 US$248,800
2025-08-29 2025-08-27 PlS Planned sale
2.2
Waddill William D.
Non-Executive Director
4,000 -30.5%
59.25
US$237,000 		4,000 -30.5% 59.25 US$237,000
2025-08-27 2025-08-27 PrS Proposed sale
2.2
WILLIAM WADDILL

Director

Non-Executive Director
4,000
56.99
US$227,960 		4,000 56.99 US$227,960
2025-07-28 2025-07-25 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
10,415 -2.0%
54.78
US$570,534 		10,415 -2.0% 54.78 US$570,534
2025-07-23 2025-07-23 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
17,520 -3.2%
54.79
US$959,921 		17,520 -3.2% 54.79 US$959,921
2025-07-23 2025-07-22 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
22,065 -3.9%
55.05
US$1,214,678 		22,065 -3.9% 55.05 US$1,214,678
2025-07-22 2025-07-22 PrS Proposed sale
2.2
Dinesh Patel

CEO
50,000
55.22
US$2,761,000 		50,000 55.22 US$2,761,000
2025-07-23 2025-07-21 S Sale
2.2
PATEL DINESH V PH D

President and CEO

Executive Director
12,859 -2.2%
54.86
US$705,445 		12,859 -2.2% 54.86 US$705,445
2025-06-11 2025-06-10 S Sale
2.9
MOLINA ARTURO MD

Chief Medical Officer

Officer
10,000 -10.7%
57.03
US$570,300 		10,000 -10.7% 57.03 US$570,300
2025-06-10 2025-06-10 PrS Proposed sale
2.9
ARTURO MOLINA

Officer

Officer
10,000
57.03
US$570,269 		10,000 57.03 US$570,269
2025-06-11 2025-06-09 S Sale
2.9
MOLINA ARTURO MD

Chief Medical Officer

Officer
10,000 -10.7%
55.51
US$555,100 		10,000 -10.7% 55.51 US$555,100
2025-06-09 2025-06-09 PrS Proposed sale
2.9
ARTURO MOLINA

Officer

Officer
10,000
55.51
US$555,077 		10,000 55.51 US$555,077
2025-04-23 2025-04-22 S Sale
2.7
Ali Asif

Chief Financial Officer

Officer
1,756 -2.8%
46.00
US$80,776 		1,756 -2.8% 46.00 US$80,776
2025-03-19 2025-03-17 PlS Planned sale
2.2
Waddill William D.
Non-Executive Director
4,000 -23.4%
54.25
US$217,000 		4,000 -23.4% 54.25 US$217,000
2025-03-17 2025-03-17 PrS Proposed sale
2.2
WILLIAM D WADDILL

Director

Non-Executive Director
4,000
54.78
US$219,120 		4,000 54.78 US$219,120
2025-03-14 2025-03-13 S Sale
2.9
MOLINA ARTURO MD

Chief Medical Officer

Officer
30,514 -26.7%
55.74
US$1,700,850 		30,514 -26.7% 55.74 US$1,700,850
2025-03-13 2025-03-13 PrS Proposed sale
2.9
MOLINA ARTURO MD

Officer

Officer
30,514
55.00
US$1,678,270 		30,514 55.00 US$1,678,270
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