United States Biotechnology & Medical Research

Apogee Therapeutics Inc (APGE)

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Apogee Therapeutics experienced significant insider selling over the past ninety days, totaling approximately $54.2 million. Key executives, including the CEO and Chief Medical Officer, executed numerous planned divestments. These activities occurred amid strong stock performance, with shares trading near fifty-two-week highs following a positive earnings report.
Ticker: APGE Exchange: NMS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Planned sale 5 Aug 2026
Value US$3,411,077.93 | Price 126.75 | Shares 84,270 (+10.1%)
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-08-07 2026-08-05 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
84,270 +10.1%
126.75
US$3,411,078 		84,270 +10.1% 126.75 US$3,411,078
2026-07-10 2026-07-08 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
79,213 -6.5%
386.77
US$2,244,473 		79,213 -6.5% 386.77 US$2,244,473
2026-07-02 2026-07-01 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
62,265 -7.5%
353.60
US$3,183,597 		62,265 -7.5% 353.60 US$3,183,597
2026-07-01 2026-07-01 PrS Proposed sale
CARL DAMBKOWSKI

Officer

Officer
16,500
132.73
US$2,190,045 		16,500 132.73 US$2,190,045
2026-06-24 2026-06-22 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
80,000 -7.3%
132.54
US$10,603,200 		80,000 -7.3% 132.54 US$10,603,200
2026-06-24 2026-06-22 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
26,400 -12.8%
132.60
US$3,500,640 		26,400 -12.8% 132.60 US$3,500,640
2026-06-22 2026-06-22 PrS Proposed sale
HENDERSON MICHAEL THOMAS

Officer; Director

Executive Director
80,000
132.54
US$10,603,532 		80,000 132.54 US$10,603,532
2026-06-22 2026-06-22 PrS Proposed sale
HENDERSON MICHAEL THOMAS

Officer; Director

Executive Director
80,000
132.54
US$10,603,532 		80,000 132.54 US$10,603,532
2026-06-22 2026-06-22 PrS Proposed sale
CARL DAMBKOWSKI

Officer

Officer
15,400
90.38
US$1,391,852 		15,400 90.38 US$1,391,852
2026-06-22 2026-06-22 PrS Proposed sale
CARL DAMBKOWSKI

Officer

Officer
15,400
90.38
US$1,391,852 		15,400 90.38 US$1,391,852
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
614 -0.1%
86.89
US$53,350 		614 -0.1% 86.89 US$53,350
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
2,305 -0.2%
86.27
US$198,852 		2,305 -0.2% 86.27 US$198,852
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
1,577 -0.1%
85.19
US$134,345 		1,577 -0.1% 85.19 US$134,345
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
1,080 -0.1%
84.18
US$90,914 		1,080 -0.1% 84.18 US$90,914
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
7,654 -0.7%
82.78
US$633,598 		7,654 -0.7% 82.78 US$633,598
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
614 -0.1%
86.89
US$53,350 		614 -0.1% 86.89 US$53,350
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
2,305 -0.2%
86.27
US$198,852 		2,305 -0.2% 86.27 US$198,852
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
1,577 -0.1%
85.19
US$134,345 		1,577 -0.1% 85.19 US$134,345
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
1,080 -0.1%
84.18
US$90,914 		1,080 -0.1% 84.18 US$90,914
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
7,654 -0.7%
82.78
US$633,598 		7,654 -0.7% 82.78 US$633,598
2026-06-12 2026-06-10 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
6,770 -0.6%
82.21
US$556,562 		6,770 -0.6% 82.21 US$556,562
2026-06-05 2026-06-03 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
5,500 -2.6%
78.71
US$432,905 		5,500 -2.6% 78.71 US$432,905
2026-05-15 2026-05-13 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
1,341 -0.1%
82.58
US$110,740 		1,341 -0.1% 82.58 US$110,740
2026-05-15 2026-05-13 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
18,659 -1.6%
82.05
US$1,530,971 		18,659 -1.6% 82.05 US$1,530,971
2026-05-13 2026-05-13 PrS Proposed sale
HENDERSON MICHAEL THOMAS

Officer; Director

Executive Director
60,000
82.47
US$4,948,200 		60,000 82.47 US$4,948,200
2026-05-08 2026-05-06 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
1,800 -0.9%
84.60
US$152,280 		1,800 -0.9% 84.60 US$152,280
2026-05-08 2026-05-06 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
3,700 -1.7%
83.92
US$310,504 		3,700 -1.7% 83.92 US$310,504
2026-05-06 2026-05-06 PrS Proposed sale
CARL DAMBKOWSKI

Officer

Officer
22,000
83.29
US$1,832,380 		22,000 83.29 US$1,832,380
2026-05-04 2026-05-01 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
289 -0.2%
83.16
US$24,033 		289 -0.2% 83.16 US$24,033
2026-05-04 2026-05-01 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
900 -0.5%
82.60
US$74,340 		900 -0.5% 82.60 US$74,340
2026-05-04 2026-05-01 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
811 -0.5%
81.02
US$65,707 		811 -0.5% 81.02 US$65,707
2026-05-01 2026-05-01 PrS Proposed sale
3.6
JANE HENDERSON

Officer

Officer
2,000
82.89
US$165,780 		2,000 82.89 US$165,780
2026-04-17 2026-04-16 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
2,000 -1.1%
90.00
US$180,000 		2,000 -1.1% 90.00 US$180,000
2026-04-10 2026-04-08 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
200 -0.0%
85.00
US$17,000 		200 -0.0% 85.00 US$17,000
2026-04-10 2026-04-08 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
2,000 -0.2%
83.26
US$166,520 		2,000 -0.2% 83.26 US$166,520
2026-04-10 2026-04-08 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
17,800 -1.5%
82.48
US$1,468,144 		17,800 -1.5% 82.48 US$1,468,144
2026-04-03 2026-04-01 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
100 -0.0%
85.89
US$8,589 		100 -0.0% 85.89 US$8,589
2026-04-03 2026-04-01 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
2,702 -1.3%
85.33
US$230,562 		2,702 -1.3% 85.33 US$230,562
2026-04-03 2026-04-01 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
2,698 -1.3%
84.31
US$227,468 		2,698 -1.3% 84.31 US$227,468
2026-04-03 2026-04-01 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
1,100 -0.6%
85.46
US$94,006 		1,100 -0.6% 85.46 US$94,006
2026-04-03 2026-04-01 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
900 -0.5%
84.46
US$76,014 		900 -0.5% 84.46 US$76,014
2026-03-27 2026-03-25 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
2,000 -1.1%
85.00
US$170,000 		2,000 -1.1% 85.00 US$170,000
2026-03-25 2026-03-25 PrS Proposed sale
3.6
JANE HENDERSON

Officer

Officer
6,000
73.00
US$438,000 		6,000 73.00 US$438,000
2026-03-13 2026-03-11 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
3,418 -0.3%
75.86
US$259,289 		3,418 -0.3% 75.86 US$259,289
2026-03-13 2026-03-11 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
8,219 -0.7%
74.83
US$615,028 		8,219 -0.7% 74.83 US$615,028
2026-03-13 2026-03-11 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
8,363 -0.7%
74.29
US$621,287 		8,363 -0.7% 74.29 US$621,287
2026-03-06 2026-03-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
200 -0.1%
73.26
US$14,652 		200 -0.1% 73.26 US$14,652
2026-03-06 2026-03-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
2,075 -1.0%
71.98
US$149,358 		2,075 -1.0% 71.98 US$149,358
2026-03-06 2026-03-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
3,225 -1.5%
70.33
US$226,814 		3,225 -1.5% 70.33 US$226,814
2026-03-04 2026-03-02 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
406 -0.2%
71.66
US$29,094 		406 -0.2% 71.66 US$29,094
2026-03-04 2026-03-02 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
994 -0.5%
70.45
US$70,027 		994 -0.5% 70.45 US$70,027
2026-03-04 2026-03-02 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
300 -0.2%
69.43
US$20,829 		300 -0.2% 69.43 US$20,829
2026-03-04 2026-03-02 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
300 -0.2%
68.27
US$20,481 		300 -0.2% 68.27 US$20,481
2026-02-13 2026-02-11 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
955 -0.1%
64.99
US$62,065 		955 -0.1% 64.99 US$62,065
2026-02-13 2026-02-11 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
7,551 -0.6%
63.73
US$481,225 		7,551 -0.6% 63.73 US$481,225
2026-02-13 2026-02-11 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
11,494 -1.0%
62.96
US$723,662 		11,494 -1.0% 62.96 US$723,662
2026-02-11 2026-02-11 PrS Proposed sale
HENDERSON MICHAEL THOMAS

Officer; Director

Executive Director
60,000
64.00
US$3,840,000 		60,000 64.00 US$3,840,000
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
200 -0.1%
68.94
US$13,788 		200 -0.1% 68.94 US$13,788
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
100 -0.0%
67.88
US$6,788 		100 -0.0% 67.88 US$6,788
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
1,299 -0.6%
66.85
US$86,838 		1,299 -0.6% 66.85 US$86,838
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
1,420 -0.7%
65.83
US$93,479 		1,420 -0.7% 65.83 US$93,479
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
2,481 -1.1%
64.88
US$160,967 		2,481 -1.1% 64.88 US$160,967
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
200 -0.1%
68.94
US$13,788 		200 -0.1% 68.94 US$13,788
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
100 -0.0%
67.88
US$6,788 		100 -0.0% 67.88 US$6,788
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
1,299 -0.6%
66.85
US$86,838 		1,299 -0.6% 66.85 US$86,838
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
1,420 -0.7%
65.83
US$93,479 		1,420 -0.7% 65.83 US$93,479
2026-02-04 2026-02-04 PlS Planned sale
Dambkowski Carl

Chief Medical Officer

Officer
2,481 -1.1%
64.88
US$160,967 		2,481 -1.1% 64.88 US$160,967
2026-02-04 2026-02-02 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
100 -0.1%
66.89
US$6,689 		100 -0.1% 66.89 US$6,689
2026-02-04 2026-02-02 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
1,108 -0.6%
66.15
US$73,294 		1,108 -0.6% 66.15 US$73,294
2026-02-04 2026-02-02 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
100 -0.1%
66.89
US$6,689 		100 -0.1% 66.89 US$6,689
2026-02-04 2026-02-02 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
1,108 -0.6%
66.15
US$73,294 		1,108 -0.6% 66.15 US$73,294
2026-02-04 2026-02-02 PlS Planned sale
3.6
Henderson Jane

Chief Financial Officer

Officer
792 -0.4%
65.21
US$51,646 		792 -0.4% 65.21 US$51,646
2026-01-22 2026-01-22 PrS Proposed sale
3.3
Fairmount Healthcare Fund II L.P.

Director

Non-Executive Director
1,750,000
76.30
US$133,525,000 		1,750,000 76.30 US$133,525,000
2026-01-22 2026-01-22 S Sale
3.3
Fairmount Funds Management LLC
Non-Executive Director
1,750,000 -85.4%
76.30
US$133,525,000 		1,750,000 -85.4% 76.30 US$133,525,000
2026-01-16 2026-01-14 PlS Planned sale
HENDERSON MICHAEL THOMAS

Chief Executive Officer

Executive Director
470 -0.0%
83.79
US$39,381 		470 -0.0% 83.79 US$39,381
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