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Ticker: DTIL Exchange: NSM


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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Total value Details
Sept. 26, 2022 Sept. 23, 2022 B Purchase

Kelly John Alexander

Chief Financial Officer

Officer
8,200 +5.3%
1.23
10,086 USD 		8,200 +5.3% 1.23 10,086 USD
Sept. 26, 2022 Sept. 22, 2022 B Purchase

Kelly John Alexander

Chief Financial Officer

Officer
37,037 +31.5%
1.34
49,630 USD 		37,037 +31.5% 1.34 49,630 USD
June 24, 2022 June 22, 2022 B Purchase

Kelly John Alexander

Chief Financial Officer

Officer
33,784 +40.3%
1.50
50,676 USD 		33,784 +40.3% 1.50 50,676 USD
March 21, 2022 March 17, 2022 B Purchase

Kelly John Alexander

Chief Financial Officer

Officer
16,677 +85.5%
3.08
51,365 USD 		16,677 +85.5% 3.08 51,365 USD
June 25, 2021 June 23, 2021 S Sale

THOMSON DAVID S.

Chief Operating Officer

Officer
30,000 -21.2%
10.65
319,500 USD 		30,000 -21.2% 10.65 319,500 USD
June 23, 2021 June 21, 2021 S Sale

THOMSON DAVID S.

Chief Operating Officer

Officer
15,000 -11.9%
10.77
161,550 USD 		15,000 -11.9% 10.77 161,550 USD
June 21, 2021 June 18, 2021 S Sale

THOMSON DAVID S.

Chief Operating Officer

Officer
10,000 -8.2%
11.00
110,000 USD 		10,000 -8.2% 11.00 110,000 USD
June 21, 2021 June 17, 2021 S Sale

THOMSON DAVID S.

Chief Operating Officer

Officer
10,000 -8.2%
10.44
104,400 USD 		10,000 -8.2% 10.44 104,400 USD
June 16, 2021 June 15, 2021 S Sale

THOMSON DAVID S.

Chief Operating Officer

Officer
2,858 -2.5%
11.20
32,010 USD 		2,858 -2.5% 11.20 32,010 USD
June 15, 2021 June 11, 2021 S Sale

THOMSON DAVID S.

Chief Operating Officer

Officer
30,000 -21.2%
11.52
345,600 USD 		30,000 -21.2% 11.52 345,600 USD
May 19, 2021 May 17, 2021 S Sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
20,000 -0.5%
9.38
187,600 USD 		20,000 -0.5% 9.38 187,600 USD
May 18, 2021 May 14, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,673 -0.2%
9.17
88,701 USD 		9,673 -0.2% 9.17 88,701 USD
May 14, 2021 May 13, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,675 -0.5%
8.96
86,688 USD 		9,675 -0.5% 8.96 86,688 USD
May 14, 2021 May 13, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,673 -0.2%
9.15
88,508 USD 		9,673 -0.2% 9.15 88,508 USD
May 14, 2021 May 12, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,676 -0.2%
8.72
84,375 USD 		9,676 -0.2% 8.72 84,375 USD
May 11, 2021 May 10, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,746 -0.5%
8.25
80,405 USD 		9,746 -0.5% 8.25 80,405 USD
May 11, 2021 May 7, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,742 -0.5%
8.57
83,489 USD 		9,742 -0.5% 8.57 83,489 USD
April 21, 2021 April 19, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,676 -0.2%
8.69
84,084 USD 		9,676 -0.2% 8.69 84,084 USD
April 19, 2021 April 16, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,675 -0.2%
8.84
85,527 USD 		9,675 -0.2% 8.84 85,527 USD
April 19, 2021 April 15, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,676 -0.2%
8.76
84,762 USD 		9,676 -0.2% 8.76 84,762 USD
March 22, 2021 March 18, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,665 -0.2%
11.08
107,088 USD 		9,665 -0.2% 11.08 107,088 USD
March 18, 2021 March 17, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,665 -0.2%
10.92
105,542 USD 		9,665 -0.2% 10.92 105,542 USD
March 18, 2021 March 16, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,661 -0.2%
11.97
115,642 USD 		9,661 -0.2% 11.97 115,642 USD
March 16, 2021 March 12, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,712 -0.5%
11.36
110,328 USD 		9,712 -0.5% 11.36 110,328 USD
March 12, 2021 March 11, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,711 -0.5%
11.38
110,511 USD 		9,711 -0.5% 11.38 110,511 USD
March 12, 2021 March 10, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,710 -0.5%
11.79
114,481 USD 		9,710 -0.5% 11.79 114,481 USD
Feb. 24, 2021 Feb. 22, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,660 -0.2%
12.04
116,306 USD 		9,660 -0.2% 12.04 116,306 USD
Feb. 22, 2021 Feb. 19, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
9,663 -0.2%
11.55
111,608 USD 		9,663 -0.2% 11.55 111,608 USD
Feb. 22, 2021 Feb. 18, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
6,871 -0.2%
12.20
83,826 USD 		6,871 -0.2% 12.20 83,826 USD
Feb. 22, 2021 Feb. 18, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,705 -0.5%
12.23
118,692 USD 		9,705 -0.5% 12.23 118,692 USD
Feb. 18, 2021 Feb. 17, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,705 -0.5%
12.28
119,177 USD 		9,705 -0.5% 12.28 119,177 USD
Feb. 18, 2021 Feb. 16, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,697 -0.5%
13.30
128,970 USD 		9,697 -0.5% 13.30 128,970 USD
Feb. 2, 2021 Jan. 29, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
6,444 -0.2%
12.25
78,939 USD 		6,444 -0.2% 12.25 78,939 USD
Jan. 29, 2021 Jan. 28, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
6,444 -0.2%
11.97
77,135 USD 		6,444 -0.2% 11.97 77,135 USD
Jan. 29, 2021 Jan. 27, 2021 PS Planned sale

JANTZ DEREK

Chief Scientific Officer

Executive Director
7,048 -0.2%
11.68
82,321 USD 		7,048 -0.2% 11.68 82,321 USD
Jan. 28, 2021 Jan. 26, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,697 -0.5%
13.37
129,649 USD 		9,697 -0.5% 13.37 129,649 USD
Jan. 26, 2021 Jan. 25, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
9,695 -0.5%
13.74
133,209 USD 		9,695 -0.5% 13.74 133,209 USD
Jan. 26, 2021 Jan. 22, 2021 PS Planned sale

KANE MATTHEW R.

President and CEO

Executive Director
10,218 -0.6%
13.53
138,250 USD 		10,218 -0.6% 13.53 138,250 USD
Jan. 25, 2021 Jan. 21, 2021 PS Planned sale

THOMSON DAVID S.

Chief Operating Officer

Officer
10,000 -8.4%
16.49
164,900 USD 		10,000 -8.4% 16.49 164,900 USD
Dec. 20, 2019 Dec. 19, 2019 B Purchase

Heery Christopher

Chief Medical Officer

Officer
2,235 +894.0%
12.08
26,999 USD 		2,235 +894.0% 12.08 26,999 USD
Dec. 20, 2019 Dec. 19, 2019 B Purchase

Heery Christopher

Chief Medical Officer

Officer
250 +inf%
12.09
3,023 USD 		250 +inf% 12.09 3,023 USD
April 4, 2019 April 3, 2019 B Purchase

YAO TONY DUNG LING

6,487 +4.3%
15.42
100,030 USD 		6,487 +4.3% 15.42 100,030 USD
April 3, 2019 April 1, 2019 B Purchase

FMR LLC

See Remark 1
50,000 +1.4%
16.00
800,000 USD 		50,000 +1.4% 16.00 800,000 USD
April 1, 2019 April 1, 2019 B Purchase

venBio Global Strategic Fund, L.P.

Major owner
50,000 +inf%
16.00
800,000 USD 		50,000 +inf% 16.00 800,000 USD

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