United States Pharmaceuticals

OPKO Health Inc (OPK)

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OPKO Health Inc. recorded its most recent insider trading activity on March 20, 2026, involving a purchase by John A. Paganelli. Prior to this, Phillip Frost executed multiple buy orders throughout November 2025. These transactions represent the latest documented equity acquisitions by company leadership.
Ticker: OPK Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
3.3
PAGANELLI JOHN A Non-Executive Director
Transaction date
Purchase
Price
219.20
Quantity 21,783 +2.1%
Value US$4,510,363
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
177.17
Quantity 98,856 +41.0%
Value US$2,520,948
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
25.48
Quantity 84,896 +3.2%
Value US$2,796,546
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.33
Quantity 89,375 +0.0%
Value US$118,422
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.32
Quantity 3,894 +0.0%
Value US$5,140
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.30
Quantity 102,371 +0.0%
Value US$133,082
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.35
Quantity 13,664 +0.0%
Value US$18,446
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.35
Quantity 1,757 +0.0%
Value US$2,363
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.34
Quantity 24,579 +0.0%
Value US$32,936
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.34
Quantity 161,818 +0.1%
Value US$216,027
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.33
Quantity 211,948 +0.1%
Value US$281,891
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.33
Quantity 47,105 +0.0%
Value US$62,414
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.32
Quantity 119,129 +0.1%
Value US$157,250
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.32
Quantity 155,496 +0.1%
Value US$205,255
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.32
Quantity 198,904 +0.1%
Value US$261,559
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.31
Quantity 66,504 +0.0%
Value US$87,120
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.31
Quantity 12,993 +0.0%
Value US$16,956
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.30
Quantity 30,082 +0.0%
Value US$39,107
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.30
Quantity 21,236 +0.0%
Value US$27,501
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.29
Quantity 300 +0.0%
Value US$387
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.29
Quantity 58,160 +0.0%
Value US$74,736
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.28
Quantity 36,325 +0.0%
Value US$46,496
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.29
Quantity 33,572 +0.0%
Value US$43,308
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.29
Quantity 83,556 +0.0%
Value US$107,369
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.28
Quantity 428 +0.0%
Value US$550
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.28
Quantity 69,728 +0.0%
Value US$89,252
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.28
Quantity 212,608 +0.1%
Value US$271,075
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.27
Quantity 1,772 +0.0%
Value US$2,250
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.27
Quantity 15,000 +0.0%
Value US$18,975
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.26
Quantity 66,635 +0.0%
Value US$83,627
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.25
Quantity 49,590 +0.0%
Value US$61,988
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.25
Quantity 410 +0.0%
Value US$510
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.42
Quantity 150,000 +0.1%
Value US$213,435
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.32
Quantity 675,000 +0.3%
Value US$891,000
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.36
Quantity 125,000 +0.1%
Value US$169,712
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.48
Quantity 125,000 +0.1%
Value US$184,650
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.65
Quantity 100,000 +0.0%
Value US$164,850
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.70
Quantity 150,000 +0.1%
Value US$254,385
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.74
Quantity 200,000 +0.1%
Value US$347,820
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.71
Quantity 67,434 +0.0%
Value US$115,312
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.47
Quantity 47,537 +0.0%
Value US$70,060
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.47
Quantity 150,000 +0.1%
Value US$220,425
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.48
Quantity 500,000 +0.2%
Value US$740,850
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.60
Quantity 125,000 +0.1%
Value US$199,375
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.56
Quantity 500,000 +0.2%
Value US$781,050
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.53
Quantity 199,072 +0.1%
Value US$305,376
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.59
Quantity 100,000 +0.0%
Value US$159,000
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.62
Quantity 100,000 +0.0%
Value US$161,980
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.50
Quantity 280,183 +0.1%
Value US$421,535
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.27
Quantity 770 +0.0%
Value US$974
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.27
Quantity 99,230 +0.0%
Value US$125,963
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
1.29
Quantity 163,997 +0.1%
Value US$211,195
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.87
Quantity 500,000 +0.2%
Value US$437,100
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.89
Quantity 500,000 +0.2%
Value US$444,300
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.93
Quantity 500,000 +0.2%
Value US$463,750
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.93
Quantity 600,000 +0.3%
Value US$559,380
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.99
Quantity 500,000 +0.2%
Value US$496,150
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.99
Quantity 1,000,000 +0.5%
Value US$991,700
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.98
Quantity 1,500,000 +0.7%
Value US$1,462,800
3.0
KRASNO RICHARD M Non-Executive Director
Transaction date
Purchase
Price
0.99
Quantity 30,000 +40.9%
Value US$29,838
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.98
Quantity 500,000 +0.2%
Value US$488,650
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.97
Quantity 400,000 +0.2%
Value US$386,200
3.8
HSIAO JANE PH D Vice Chairman & CTO Executive Director
Transaction date
Purchase
Price
0.95
Quantity 150,000 +0.5%
Value US$142,500
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.95
Quantity 1,000,000 +0.5%
Value US$954,300
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.94
Quantity 511,531 +0.3%
Value US$480,379
2.2
Nabel Gary J. Chief Innovation Officer Executive Director
Transaction date
Purchase
Price
0.93
Quantity 106,989 +21397.8%
Value US$99,425
2.2
Nabel Gary J. Chief Innovation Officer Executive Director
Transaction date
Purchase
Price
0.92
Quantity 500 +inf%
Value US$459
2.2
Nabel Gary J. Chief Innovation Officer Executive Director
Transaction date
Purchase
Price
0.93
Quantity 108,695 +44.8%
Value US$100,543
3.8
HSIAO JANE PH D Vice Chairman & CTO Executive Director
Transaction date
Purchase
Price
0.87
Quantity 150,010 +0.5%
Value US$130,899
2.3
FROST PHILLIP MD ET AL CEO & Chairman Executive Director Large shareholder
Transaction date
Purchase
Price
0.90
Quantity 1,500,000 +0.7%
Value US$1,344,600
3.3
PAGANELLI JOHN A Non-Executive Director
Transaction date
Purchase
Price
0.88
Quantity 25,000 +7.0%
Value US$22,080
3.2
Zerhouni Elias A. Vice Chairman and President Executive Director
Transaction date
Purchase
Price
0.94
Quantity 400,000 +2.0%
Value US$376,000
3.2
Zerhouni Elias A. Vice Chairman and President Executive Director
Transaction date
Purchase
Price
0.93
Quantity 100,000 +0.5%
Value US$93,000
3.2
Zerhouni Elias A. Vice Chairman and President Executive Director
Transaction date
Purchase
Price
0.91
Quantity 33,300 +0.2%
Value US$30,303
3.2
Zerhouni Elias A. Vice Chairman and President Executive Director
Transaction date
Purchase
Price
0.87
Quantity 17,000 +0.1%
Value US$14,790
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-03-20 2026-03-20 B Purchase
3.3
PAGANELLI JOHN A
Non-Executive Director
21,783 +2.1%
219.20
US$4,510,363 		21,783 +2.1% 219.20 US$4,510,363
2025-11-21 2025-11-21 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
98,856 +41.0%
177.17
US$2,520,948 		98,856 +41.0% 177.17 US$2,520,948
2025-11-21 2025-11-21 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
84,896 +3.2%
25.48
US$2,796,546 		84,896 +3.2% 25.48 US$2,796,546
2025-11-21 2025-11-21 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
89,375 +0.0%
1.33
US$118,422 		89,375 +0.0% 1.33 US$118,422
2025-11-21 2025-11-21 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
3,894 +0.0%
1.32
US$5,140 		3,894 +0.0% 1.32 US$5,140
2025-11-21 2025-11-21 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
102,371 +0.0%
1.30
US$133,082 		102,371 +0.0% 1.30 US$133,082
2025-11-20 2025-11-20 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
13,664 +0.0%
1.35
US$18,446 		13,664 +0.0% 1.35 US$18,446
2025-11-20 2025-11-20 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
1,757 +0.0%
1.35
US$2,363 		1,757 +0.0% 1.35 US$2,363
2025-11-20 2025-11-20 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
24,579 +0.0%
1.34
US$32,936 		24,579 +0.0% 1.34 US$32,936
2025-11-20 2025-11-20 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
161,818 +0.1%
1.34
US$216,027 		161,818 +0.1% 1.34 US$216,027
2025-11-20 2025-11-20 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
211,948 +0.1%
1.33
US$281,891 		211,948 +0.1% 1.33 US$281,891
2025-11-20 2025-11-20 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
47,105 +0.0%
1.33
US$62,414 		47,105 +0.0% 1.33 US$62,414
2025-11-20 2025-11-20 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
119,129 +0.1%
1.32
US$157,250 		119,129 +0.1% 1.32 US$157,250
2025-11-19 2025-11-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
155,496 +0.1%
1.32
US$205,255 		155,496 +0.1% 1.32 US$205,255
2025-11-19 2025-11-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
198,904 +0.1%
1.32
US$261,559 		198,904 +0.1% 1.32 US$261,559
2025-11-19 2025-11-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
66,504 +0.0%
1.31
US$87,120 		66,504 +0.0% 1.31 US$87,120
2025-11-19 2025-11-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
12,993 +0.0%
1.31
US$16,956 		12,993 +0.0% 1.31 US$16,956
2025-11-19 2025-11-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
30,082 +0.0%
1.30
US$39,107 		30,082 +0.0% 1.30 US$39,107
2025-11-19 2025-11-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
21,236 +0.0%
1.30
US$27,501 		21,236 +0.0% 1.30 US$27,501
2025-11-19 2025-11-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
300 +0.0%
1.29
US$387 		300 +0.0% 1.29 US$387
2025-11-19 2025-11-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
58,160 +0.0%
1.29
US$74,736 		58,160 +0.0% 1.29 US$74,736
2025-11-19 2025-11-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
36,325 +0.0%
1.28
US$46,496 		36,325 +0.0% 1.28 US$46,496
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
33,572 +0.0%
1.29
US$43,308 		33,572 +0.0% 1.29 US$43,308
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
83,556 +0.0%
1.29
US$107,369 		83,556 +0.0% 1.29 US$107,369
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
428 +0.0%
1.28
US$550 		428 +0.0% 1.28 US$550
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
69,728 +0.0%
1.28
US$89,252 		69,728 +0.0% 1.28 US$89,252
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
212,608 +0.1%
1.28
US$271,075 		212,608 +0.1% 1.28 US$271,075
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
1,772 +0.0%
1.27
US$2,250 		1,772 +0.0% 1.27 US$2,250
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
15,000 +0.0%
1.27
US$18,975 		15,000 +0.0% 1.27 US$18,975
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
66,635 +0.0%
1.26
US$83,627 		66,635 +0.0% 1.26 US$83,627
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
49,590 +0.0%
1.25
US$61,988 		49,590 +0.0% 1.25 US$61,988
2025-11-18 2025-11-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
410 +0.0%
1.25
US$510 		410 +0.0% 1.25 US$510
2025-10-31 2025-10-31 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
150,000 +0.1%
1.42
US$213,435 		150,000 +0.1% 1.42 US$213,435
2025-08-08 2025-08-08 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
675,000 +0.3%
1.32
US$891,000 		675,000 +0.3% 1.32 US$891,000
2025-04-10 2025-04-10 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
125,000 +0.1%
1.36
US$169,712 		125,000 +0.1% 1.36 US$169,712
2025-04-08 2025-04-08 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
125,000 +0.1%
1.48
US$184,650 		125,000 +0.1% 1.48 US$184,650
2025-04-01 2025-04-01 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
100,000 +0.0%
1.65
US$164,850 		100,000 +0.0% 1.65 US$164,850
2025-03-28 2025-03-28 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
150,000 +0.1%
1.70
US$254,385 		150,000 +0.1% 1.70 US$254,385
2025-03-17 2025-03-17 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
200,000 +0.1%
1.74
US$347,820 		200,000 +0.1% 1.74 US$347,820
2025-02-28 2025-02-28 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
67,434 +0.0%
1.71
US$115,312 		67,434 +0.0% 1.71 US$115,312
2025-01-28 2025-01-28 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
47,537 +0.0%
1.47
US$70,060 		47,537 +0.0% 1.47 US$70,060
2025-01-17 2025-01-17 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
150,000 +0.1%
1.47
US$220,425 		150,000 +0.1% 1.47 US$220,425
2025-01-15 2025-01-15 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
500,000 +0.2%
1.48
US$740,850 		500,000 +0.2% 1.48 US$740,850
2024-12-13 2024-12-13 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
125,000 +0.1%
1.60
US$199,375 		125,000 +0.1% 1.60 US$199,375
2024-12-11 2024-12-11 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
500,000 +0.2%
1.56
US$781,050 		500,000 +0.2% 1.56 US$781,050
2024-11-29 2024-11-29 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
199,072 +0.1%
1.53
US$305,376 		199,072 +0.1% 1.53 US$305,376
2024-11-22 2024-11-22 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
100,000 +0.0%
1.59
US$159,000 		100,000 +0.0% 1.59 US$159,000
2024-11-14 2024-11-14 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
100,000 +0.0%
1.62
US$161,980 		100,000 +0.0% 1.62 US$161,980
2024-11-08 2024-11-08 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
280,183 +0.1%
1.50
US$421,535 		280,183 +0.1% 1.50 US$421,535
2024-05-23 2024-05-23 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
770 +0.0%
1.27
US$974 		770 +0.0% 1.27 US$974
2024-05-23 2024-05-23 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
99,230 +0.0%
1.27
US$125,963 		99,230 +0.0% 1.27 US$125,963
2024-05-17 2024-05-17 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
163,997 +0.1%
1.29
US$211,195 		163,997 +0.1% 1.29 US$211,195
2024-03-18 2024-03-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
500,000 +0.2%
0.87
US$437,100 		500,000 +0.2% 0.87 US$437,100
2024-03-14 2024-03-14 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
500,000 +0.2%
0.89
US$444,300 		500,000 +0.2% 0.89 US$444,300
2024-03-13 2024-03-13 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
500,000 +0.2%
0.93
US$463,750 		500,000 +0.2% 0.93 US$463,750
2024-03-12 2024-03-12 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
600,000 +0.3%
0.93
US$559,380 		600,000 +0.3% 0.93 US$559,380
2024-02-28 2024-02-28 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
500,000 +0.2%
0.99
US$496,150 		500,000 +0.2% 0.99 US$496,150
2024-02-21 2024-02-21 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
1,000,000 +0.5%
0.99
US$991,700 		1,000,000 +0.5% 0.99 US$991,700
2024-02-07 2024-02-07 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
1,500,000 +0.7%
0.98
US$1,462,800 		1,500,000 +0.7% 0.98 US$1,462,800
2024-01-29 2024-01-29 B Purchase
3.0
KRASNO RICHARD M
Non-Executive Director
30,000 +40.9%
0.99
US$29,838 		30,000 +40.9% 0.99 US$29,838
2024-01-19 2024-01-19 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
500,000 +0.2%
0.98
US$488,650 		500,000 +0.2% 0.98 US$488,650
2024-01-18 2024-01-18 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
400,000 +0.2%
0.97
US$386,200 		400,000 +0.2% 0.97 US$386,200
2024-01-17 2024-01-17 B Purchase
3.8
HSIAO JANE PH D

Vice Chairman & CTO

Executive Director
150,000 +0.5%
0.95
US$142,500 		150,000 +0.5% 0.95 US$142,500
2024-01-16 2024-01-16 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
1,000,000 +0.5%
0.95
US$954,300 		1,000,000 +0.5% 0.95 US$954,300
2024-01-11 2024-01-11 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
511,531 +0.3%
0.94
US$480,379 		511,531 +0.3% 0.94 US$480,379
2024-01-10 2024-01-08 B Purchase
2.2
Nabel Gary J.

Chief Innovation Officer

Executive Director
106,989 +21397.8%
0.93
US$99,425 		106,989 +21397.8% 0.93 US$99,425
2024-01-10 2024-01-08 B Purchase
2.2
Nabel Gary J.

Chief Innovation Officer

Executive Director
500 +inf%
0.92
US$459 		500 +inf% 0.92 US$459
2024-01-10 2024-01-08 B Purchase
2.2
Nabel Gary J.

Chief Innovation Officer

Executive Director
108,695 +44.8%
0.93
US$100,543 		108,695 +44.8% 0.93 US$100,543
2024-01-08 2024-01-05 B Purchase
3.8
HSIAO JANE PH D

Vice Chairman & CTO

Executive Director
150,010 +0.5%
0.87
US$130,899 		150,010 +0.5% 0.87 US$130,899
2024-01-08 2024-01-05 B Purchase
2.3
FROST PHILLIP MD ET AL

CEO & Chairman

Executive Director Large shareholder
1,500,000 +0.7%
0.90
US$1,344,600 		1,500,000 +0.7% 0.90 US$1,344,600
2024-01-05 2024-01-05 B Purchase
3.3
PAGANELLI JOHN A
Non-Executive Director
25,000 +7.0%
0.88
US$22,080 		25,000 +7.0% 0.88 US$22,080
2024-01-05 2024-01-05 B Purchase
3.2
Zerhouni Elias A.

Vice Chairman and President

Executive Director
400,000 +2.0%
0.94
US$376,000 		400,000 +2.0% 0.94 US$376,000
2024-01-05 2024-01-05 B Purchase
3.2
Zerhouni Elias A.

Vice Chairman and President

Executive Director
100,000 +0.5%
0.93
US$93,000 		100,000 +0.5% 0.93 US$93,000
2024-01-05 2024-01-05 B Purchase
3.2
Zerhouni Elias A.

Vice Chairman and President

Executive Director
33,300 +0.2%
0.91
US$30,303 		33,300 +0.2% 0.91 US$30,303
2024-01-05 2024-01-05 B Purchase
3.2
Zerhouni Elias A.

Vice Chairman and President

Executive Director
17,000 +0.1%
0.87
US$14,790 		17,000 +0.1% 0.87 US$14,790
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