|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
78,746
-44.0%
13.85
US$3,578,173
|
78,746
-44.0%
|
13.85
|
US$3,578,173
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
47,914
-28.7%
61.77
US$3,144,547
|
47,914
-28.7%
|
61.77
|
US$3,144,547
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
33,597
-10.1%
163.96
US$3,650,702
|
33,597
-10.1%
|
163.96
|
US$3,650,702
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.55
US$55
|
100
+0.0%
|
0.55
|
US$55
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
963
+0.1%
0.75
US$722
|
963
+0.1%
|
0.75
|
US$722
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
200
+0.0%
0.74
US$148
|
200
+0.0%
|
0.74
|
US$148
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
800
+0.1%
0.70
US$560
|
800
+0.1%
|
0.70
|
US$560
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
500
+0.1%
0.69
US$345
|
500
+0.1%
|
0.69
|
US$345
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
500
+0.1%
0.68
US$340
|
500
+0.1%
|
0.68
|
US$340
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.67
US$67
|
100
+0.0%
|
0.67
|
US$67
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
400
+0.1%
0.63
US$252
|
400
+0.1%
|
0.63
|
US$252
|
|
|
2008-11-19 |
2008-11-19 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.56
US$56
|
100
+0.0%
|
0.56
|
US$56
|
|
|
2008-11-19 |
2008-11-18 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
300
+0.0%
0.59
US$177
|
300
+0.0%
|
0.59
|
US$177
|
|
|
2008-11-19 |
2008-11-18 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
500
+0.1%
0.56
US$280
|
500
+0.1%
|
0.56
|
US$280
|
|
|
2008-11-19 |
2008-11-18 |
B
Purchase
|
Laikind Paul K
Chief Executive Officer
Officer
|
100
+0.0%
0.51
US$51
|
100
+0.0%
|
0.51
|
US$51
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
45,239
+37.6%
2.34
US$105,859
|
45,239
+37.6%
|
2.34
|
US$105,859
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
45,239
+37.6%
2.34
US$105,859
|
45,239
+37.6%
|
2.34
|
US$105,859
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
EVNIN LUKE
Non-Executive Director
Large shareholder
|
71,866
+1.5%
2.34
US$168,166
|
71,866
+1.5%
|
2.34
|
US$168,166
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
MPM BIOVENTURES II QP LP
Large shareholder
|
71,866
+1.5%
2.34
US$168,166
|
71,866
+1.5%
|
2.34
|
US$168,166
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
945,577
+37.7%
2.34
US$2,212,650
|
945,577
+37.7%
|
2.34
|
US$2,212,650
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
CREDIT SUISSE/
Large shareholder
|
196,633
+5.4%
2.34
US$460,121
|
196,633
+5.4%
|
2.34
|
US$460,121
|
|
|
2008-04-18 |
2008-04-16 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
945,577
+37.7%
2.34
US$2,212,650
|
945,577
+37.7%
|
2.34
|
US$2,212,650
|
|
|
2008-04-17 |
2008-04-16 |
B
Purchase
|
HALE DAVID F
Non-Executive Director
|
10,000
+19.9%
2.34
US$23,400
|
10,000
+19.9%
|
2.34
|
US$23,400
|
|
|
2007-06-21 |
2007-06-19 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
2,611
-1.1%
8.08
US$21,097
|
2,611
-1.1%
|
8.08
|
US$21,097
|
|
|
2007-06-21 |
2007-06-19 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
100
-0.0%
8.06
US$806
|
100
-0.0%
|
8.06
|
US$806
|
|
|
2007-06-21 |
2007-06-19 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
100
-0.0%
8.03
US$803
|
100
-0.0%
|
8.03
|
US$803
|
|
|
2007-06-21 |
2007-06-19 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
100
-0.0%
8.04
US$804
|
100
-0.0%
|
8.04
|
US$804
|
|
|
2007-06-21 |
2007-06-19 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
489
-0.2%
8.05
US$3,936
|
489
-0.2%
|
8.05
|
US$3,936
|
|
|
2007-06-05 |
2007-06-01 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
400
-100.0%
8.01
US$3,204
|
400
-100.0%
|
8.01
|
US$3,204
|
|
|
2007-06-05 |
2007-06-01 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
9,635
-96.0%
8.00
US$77,080
|
9,635
-96.0%
|
8.00
|
US$77,080
|
|
|
2007-05-24 |
2007-05-22 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
300
-0.1%
8.00
US$2,400
|
300
-0.1%
|
8.00
|
US$2,400
|
|
|
2007-04-25 |
2007-04-25 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,300
-1.4%
8.13
US$26,829
|
3,300
-1.4%
|
8.13
|
US$26,829
|
|
|
2007-04-25 |
2007-04-24 |
PlS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP of Business Development
Officer
|
1,800
-37.4%
8.24
US$14,832
|
1,800
-37.4%
|
8.24
|
US$14,832
|
|
|
2007-04-25 |
2007-04-24 |
PlS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP of Business Development
Officer
|
2,500
-34.2%
8.18
US$20,450
|
2,500
-34.2%
|
8.18
|
US$20,450
|
|
|
2007-04-10 |
2007-04-10 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
6,172
-38.1%
8.00
US$49,376
|
6,172
-38.1%
|
8.00
|
US$49,376
|
|
|
2007-04-10 |
2007-04-09 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
1,828
-10.1%
8.00
US$14,624
|
1,828
-10.1%
|
8.00
|
US$14,624
|
|
|
2007-02-28 |
2007-02-26 |
PlS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP of Business Development
Officer
|
700
-8.7%
8.00
US$5,600
|
700
-8.7%
|
8.00
|
US$5,600
|
|
|
2007-02-27 |
2007-02-26 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,300
-1.3%
8.00
US$26,400
|
3,300
-1.3%
|
8.00
|
US$26,400
|
|
|
2006-12-05 |
2006-12-05 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,000
-32.1%
8.00
US$24,000
|
3,000
-32.1%
|
8.00
|
US$24,000
|
|
|
2006-12-05 |
2006-12-05 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,000
-32.1%
8.00
US$24,000
|
3,000
-32.1%
|
8.00
|
US$24,000
|
|
|
2006-12-05 |
2006-12-05 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
3,000
-32.1%
8.00
US$24,000
|
3,000
-32.1%
|
8.00
|
US$24,000
|
|
|
2006-11-29 |
2006-11-27 |
PlS
Planned sale
|
Beck John W
CFO
Officer
|
100
-0.0%
8.00
US$800
|
100
-0.0%
|
8.00
|
US$800
|
|
|
2006-11-29 |
2006-11-27 |
PlS
Planned sale
|
Beck John W
CFO
Officer
|
200
-0.1%
8.01
US$1,602
|
200
-0.1%
|
8.01
|
US$1,602
|
|
|
2006-11-29 |
2006-11-27 |
PlS
Planned sale
|
Beck John W
CFO
Officer
|
200
-0.1%
8.02
US$1,604
|
200
-0.1%
|
8.02
|
US$1,604
|
|
|
2006-11-13 |
2006-11-08 |
PlS
Planned sale
|
Beck John W
Sr. VP, Finance & CFO
Officer
|
3,000
-24.3%
8.00
US$24,000
|
3,000
-24.3%
|
8.00
|
US$24,000
|
|
|
2006-11-13 |
2006-11-08 |
PlS
Planned sale
|
Beck John W
Sr. VP, Finance & CFO
Officer
|
3,000
-24.3%
8.00
US$24,000
|
3,000
-24.3%
|
8.00
|
US$24,000
|
|
|
2006-11-13 |
2006-11-08 |
PlS
Planned sale
|
Beck John W
Sr. VP, Finance & CFO
Officer
|
3,000
-24.3%
8.00
US$24,000
|
3,000
-24.3%
|
8.00
|
US$24,000
|
|
|
2006-11-07 |
2006-11-03 |
B
Purchase
|
CREDIT SUISSE/
Large shareholder
|
527,000
+17.4%
7.17
US$3,776,324
|
527,000
+17.4%
|
7.17
|
US$3,776,324
|
|
|
2006-06-28 |
2006-06-26 |
PlS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP, Business Development
Officer
|
250
-21.9%
8.35
US$2,088
|
250
-21.9%
|
8.35
|
US$2,088
|
|
|
2006-06-28 |
2006-06-26 |
PlS
Planned sale
|
Baracchini Edgardo Jr
Sr. VP, Business Development
Officer
|
250
-21.9%
8.35
US$2,088
|
250
-21.9%
|
8.35
|
US$2,088
|
|
|
2006-05-24 |
2006-05-22 |
B
Purchase
|
CASH HARVEY B
Large shareholder
|
39,836
+391.9%
8.02
US$319,648
|
39,836
+391.9%
|
8.02
|
US$319,648
|
|
|
2006-05-24 |
2006-05-19 |
B
Purchase
|
CASH HARVEY B
Large shareholder
|
5,000
+96.8%
8.10
US$40,500
|
5,000
+96.8%
|
8.10
|
US$40,500
|
|
|
2006-05-24 |
2006-05-18 |
B
Purchase
|
CASH HARVEY B
Large shareholder
|
700
+15.7%
8.10
US$5,670
|
700
+15.7%
|
8.10
|
US$5,670
|
|
|
2006-05-24 |
2006-05-16 |
B
Purchase
|
CASH HARVEY B
Large shareholder
|
4,464
+inf%
8.00
US$35,706
|
4,464
+inf%
|
8.00
|
US$35,706
|
|
|
2007-03-09 |
2006-03-01 |
PlS
Planned sale
|
Beck John W
Chief Financial Officer
Officer
|
1,000
-5.3%
8.00
US$8,000
|
1,000
-5.3%
|
8.00
|
US$8,000
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
CREDIT SUISSE/
Large shareholder
|
341,297
+20.7%
5.86
US$2,000,000
|
341,297
+20.7%
|
5.86
|
US$2,000,000
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
19,497
+19.4%
5.86
US$114,252
|
19,497
+19.4%
|
5.86
|
US$114,252
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
407,124
+19.4%
5.86
US$2,385,747
|
407,124
+19.4%
|
5.86
|
US$2,385,747
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
19,497
+19.4%
5.86
US$114,252
|
19,497
+19.4%
|
5.86
|
US$114,252
|
|
|
2005-10-04 |
2005-09-30 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
407,124
+19.4%
5.86
US$2,385,747
|
407,124
+19.4%
|
5.86
|
US$2,385,747
|
|
|
2005-11-04 |
2005-09-07 |
B
Purchase
|
Gschwend Heinz W
Non-Executive Director
|
2,000
+5.7%
4.00
US$8,000
|
2,000
+5.7%
|
4.00
|
US$8,000
|
|
|
2005-11-04 |
2005-08-22 |
B
Purchase
|
Gschwend Heinz W
Non-Executive Director
|
3,000
+9.4%
4.36
US$13,080
|
3,000
+9.4%
|
4.36
|
US$13,080
|
|
|
2005-01-24 |
2004-12-22 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
500
+inf%
6.84
US$3,420
|
500
+inf%
|
6.84
|
US$3,420
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
5,941
+inf%
7.00
US$41,587
|
5,941
+inf%
|
7.00
|
US$41,587
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
124,059
+inf%
7.00
US$868,413
|
124,059
+inf%
|
7.00
|
US$868,413
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
5,941
+inf%
7.00
US$41,587
|
5,941
+inf%
|
7.00
|
US$41,587
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
INTERWEST PARTNERS VII L P
Large shareholder
|
124,059
+inf%
7.00
US$868,413
|
124,059
+inf%
|
7.00
|
US$868,413
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
5,941
+inf%
7.00
US$41,587
|
5,941
+inf%
|
7.00
|
US$41,587
|
|
|
2004-06-23 |
2004-06-21 |
B
Purchase
|
ORONSKY ARNOLD L
Non-Executive Director
Large shareholder
|
124,059
+inf%
7.00
US$868,413
|
124,059
+inf%
|
7.00
|
US$868,413
|
|
|
2004-06-21 |
2004-06-21 |
B
Purchase
|
MPM BIOVENTURES II QP LP
Large shareholder
|
357,000
+10.4%
7.00
US$2,499,000
|
357,000
+10.4%
|
7.00
|
US$2,499,000
|
|
|
2004-06-21 |
2004-06-21 |
B
Purchase
|
EVNIN LUKE
Non-Executive Director
Large shareholder
|
357,000
+10.4%
7.00
US$2,499,000
|
357,000
+10.4%
|
7.00
|
US$2,499,000
|
|