ISOTIS S.A.

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Wolters P.

1 purchase — total 18,700 CHF

Buy 2 May 2006

Value CHF2,674,077.82 | Price 36.32 | Shares 68,341

Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Insider and/or position	Nb. shares Price Value	Number of shares	Price	Value	Details
2006-05-02	2006-05-02	B Purchase	Wolters P.	68,341 36.32 CHF2,674,078	68,341	36.32	CHF2,674,078

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